Chemico-Biological Interactions

Papers
(The median citation count of Chemico-Biological Interactions is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)
ArticleCitations
Retraction notice to “Agonism of GPR120 prevents ox-LDL-induced attachment of monocytes to endothelial cells” [Chem. Biol. Interact. 316 (2020) 108916]372
Retraction notice to “Zinc moderates circular RNA CircFOXP1 expression in order to regulate ferroptosis during lung adenocarcinoma” [Chem. Biol. Interact. 352 (25 January 2022) 109760]158
Retraction notice to “Potential of β-elemene induced ferroptosis through Pole2-mediated p53 and PI3K/AKT signaling in lung cancer cells” [Chem. Biol. Interact. 365 (25 September 2022) 110088]118
The modulator action of thiamine against pentylenetetrazole-induced seizures, apoptosis, nitric oxide, and oxidative stress in rats and SH-SY5Y neuronal cell line116
Human carboxylesterase 1A plays a predominant role in the hydrolytic activation of remdesivir in humans109
Targeting eosinophils in chronic respiratory diseases using nanotechnology-based drug delivery100
Alpha-tubulin relocalization is involved in calcium oxalate-induced tight junction disruption in renal epithelial cells95
Vascular endothelial effects of dibutyl phthalate: In vitro and in vivo evidence92
ER stress-enhanced HMGA2 plays an important role in Cr (VI)-induced glycolysis and inhibited oxidative phosphorylation by targeting the transcription of ATF487
Inhibitory effect of imperatorin on dabrafenib metabolism in vitro and in vivo71
Cytotoxic and radical activities of metal-organic framework modified with iron oxide: Biological and physico-chemical analyses63
Proteomic profiling reveals an association between ALDH and oxidative phosphorylation and DNA damage repair pathways in human colon adenocarcinoma stem cells61
Effects of the antitumor drugs adagrasib and asciminib on apixaban metabolism in vitro and in vivo61
α-Lipoic acid improves mitochondrial biogenesis and dynamics by enhancing antioxidant and inhibiting Wnt/Ca2+ pathway to relieve fluoride-induced hepatotoxic injury54
Ligand-independent activation of AhR by hydroquinone mediates benzene-induced hematopoietic toxicity52
Bisphenol A and genistein have opposite effects on adult chicken ovary by acting on ERα/Nrf2-Keap1-signaling pathway51
HO-1 activation contributes to cadmium-induced ferroptosis in renal tubular epithelial cells via increasing the labile iron pool and promoting mitochondrial ROS generation49
Solid lipid nanoparticle: A potent vehicle of the kaempferol for brain delivery through the blood-brain barrier in the focal cerebral ischemic rat49
Selenium binding protein 1 protects renal tubular epithelial cells from ferroptosis by upregulating glutathione peroxidase 448
A 50-gene biomarker identifies estrogen receptor-modulating chemicals in a microarray compendium48
Methylglyoxal induces cardiac dysfunction through mechanisms involving altered intracellular calcium handling in the rat heart46
Theaflavin-3-gallate, a natural antagonist for Hsp90: In-silico and in-vitro approach46
Galium aparine L. protects against acetaminophen-induced hepatotoxicity in rats46
Air pollution-regulated E-cadherin mediates contact inhibition of proliferation via the hippo signaling pathways in emphysema45
Icaritin activates p53 and inhibits aerobic glycolysis in liver cancer cells44
Metformin promotes the survival of random skin flaps via the activation of Nrf2/HO-1 signaling44
Biochemical interaction of pyrvinium in gentamicin-induced acute kidney injury by modulating calcium dyshomeostasis and mitochondrial dysfunction43
Non-targeting siRNA-mediated responses are associated with apoptosis in chemotherapy-induced senescent skin cancer cells42
Testing of the inhibitory effects of loratadine and desloratadine on SARS-CoV-2 spike pseudotyped virus viropexis42
Antiviral potential of diminazene aceturate against SARS-CoV-2 proteases using computational and in vitro approaches41
3-MCPD (3-monochloro-1,2-propanediol) inhibit myogenic differentiation in murine skeletal myoblasts41
Re-appraising the role of flavonols, flavones and flavonones on osteoblasts and osteoclasts- A review on its molecular mode of action40
Urea cycle promotion via ammonia-upregulated CPS1 is involved in arsenite-induced pulmonary fibrosis through enhancing collagen synthesis39
Physiological oxygen and co-culture with human fibroblasts facilitate in vivo-like properties in human renal proximal tubular epithelial cells39
Hydroxygenkwanin suppresses peritoneal metastasis in colorectal cancer by modulating tumor-associated macrophages polarization39
Characterization of a LuxR repressor for 3,17β-HSD in Comamonas testosteroni ATCC1199638
Taurine induces hormesis in multiple biological models: May have transformative implications for overall societal health35
The role of cyclin-dependent kinase inhibitor 3 in the proliferation and migration of renal cell carcinoma35
γ-Glutamylcysteine attenuates amyloid-β oligomers-induced neuroinflammation in microglia via blocking NF-κB signaling pathway35
Exploring Asphodelus microcarpus as a source of xanthine oxidase inhibitors: Insights from in silico and in vitro studies35
7, 8-Dihydroxy-4-methyl coumarin alleviates cholestasis via activation of the Farnesoid X receptor in vitro and in vivo34
Gypenoside XLIX alleviates intestinal injury by inhibiting sepsis-induced inflammation, oxidative stress, apoptosis, and autophagy34
Cisatracurium regulates the CXCR4/let-7a-5p axis to inhibit colorectal cancer progression by suppressing TGF-β/SMAD2/3 signalling33
Myrsinoic acid B from Myrsine coriacea reverses depressive-like behavior and brain oxidative stress in streptozotocin-diabetic rats33
Toxicity of nanomixtures to human macrophages: Joint action of silver and polystyrene nanoparticles33
BjussuMP-II, a venom metalloproteinase, induces the release and cleavage of pro-inflammatory cytokines and disrupts human umbilical vein endothelial cells32
Dipyridophenazine iridium(III) complex as a phototoxic cancer stem cell selective, mitochondria targeting agent32
Molecular mechanisms underlying chemopreventive potential of butein: Current trends and future perspectives32
Harnessing the dual role of polysaccharides in treating gastrointestinal diseases: As therapeutics and polymers for drug delivery32
Sodium aescinate induces renal toxicity by promoting Nrf2/GPX4-mediated ferroptosis32
Autophagy aggravates multi-walled carbon nanotube-induced ferroptosis by suppressing PGC-1 dependent-mitochondrial biogenesis in lung epithelial cells31
TRP channels in COVID-19 disease: Potential targets for prevention and treatment31
Salvianolic acid A attenuates non-alcoholic fatty liver disease by regulating the AMPK-IGFBP1 pathway31
Editorial Board31
Hemocompatible L-Type amino acid transporter 1 (LAT1)-Utilizing prodrugs of perforin inhibitors can accumulate into the pancreas and alleviate inflammation-induced apoptosis31
Natural soluble epoxide hydrolase inhibitors from Inula britanica and their potential interactions with soluble epoxide hydrolase: Insight from inhibition kinetics and molecular dynamics30
Modulation of the miR-122/Sirt-6/ACE2 axis on experimentally-induced myocardial infarction30
Induction of cardiotoxicity in zebrafish embryos by 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene through the JAK-STAT and NOTCH signaling pathways29
Molecular interactions of hesperidin with DMPC/cholesterol bilayers29
Editorial Board28
Editorial Board28
Comparisons of the immunological landscape of COVID-19 patients based on sex and disease severity by multi-omics analysis28
An in vitro alveolar model allows for the rapid assessment of chemical respiratory sensitization with modifiable biomarker endpoints28
Bis-(3-amino-2-pyridine) diselenide improves psychiatric disorders –atopic dermatitis comorbidity by regulating inflammatory and oxidative status in mice28
Editorial Board28
Computational study to find the goat serum albumin (GSA) binding site as A-esterase27
Discovery of a novel jellyfish venom metalloproteinase inhibitor from secondary metabolites isolated from jellyfish-derived fungus Aspergillus versicolor SmT0727
Role of Wnt/β-catenin signaling pathway in ameloblast differentiation in relevance to dental fluorosis26
Perspectives on using bacteriophages in biogerontology research and interventions26
Emerging applications and prospects of NFκB decoy oligodeoxynucleotides in managing respiratory diseases26
Comments on “Dihydroartemisinin induces pyroptosis by promoting the AIM2/caspase-3/DFNA5 axis in breast cancer cells."25
Behavioral and neurochemical effects in mice after one-generation exposure to low doses of manganese: Focus on offspring development25
Regulatory effects of non-steroidal anti-inflammatory drugs on cardiac ion channels Nav1.5 and Kv11.125
Aucubin produces anti-osteoporotic effects under mechanical stretch stress and orthodontic tooth movement25
Editorial Board25
Editorial Board25
Nickel induces mitochondrial damage in renal cells in vitro and in vivo through its effects on mitochondrial biogenesis, fusion, and fission25
Different concentrations of betaxolol switch cell fate between necroptosis, apoptosis, and senescence in human corneal stromal cells25
Evi1 involved in benzene-induced haematotoxicity via modulation of PI3K/mTOR pathway and negative regulation Serpinb224
Comprehensive analysis of cellular estrogen signaling in representative estrogen receptor ligands24
Inactivation of ricin by constituents present in a skin decontamination lotion24
Honokiol inhibits interleukin-induced angiogenesis in the NSCLC microenvironment through the NF-κB signaling pathway24
Chromenopyrimidinone exhibit antitumor effects through inhibition of CAP1 (Adenylyl cyclase-associated protein 1) expression in hepatocellular carcinoma24
AhR regulates VEGF expression by promoting STAT1 transcriptional activity, thereby affecting endothelial angiogenesis in acute limb ischemia24
Epinephrine facilitates the growth of T cell lymphoma by altering cell proliferation, apoptosis, and glucose metabolism24
A new reduced chalcone-derivative affects the membrane permeability and electric potential of multidrug-resistant Enterococcus faecalis24
Inhibition of AKR1Cs by liquiritigenin and the structural basis23
Solidagenone in vivo leishmanicidal activity acting in tissue repair response, and immunomodulatory capacity in Leishmania amazonensis23
Risk prediction of drug-drug interaction potential of phenytoin and miconazole topical formulations23
Editorial Board23
No-observed-adverse-effect-level (NOAEL) assessment as an optimized dose of cholinesterase reactivators for the treatment of exposure to warfare nerve agents in mice22
Antitumor activity, DNA and BSA interactions of novel copper(II) complexes with 3,4-dihydro-2(1H)-quinoxalinones22
Editorial Board22
Editorial Board22
Casticin ameliorates osteoarthritic cartilage damage in rats through PI3K/AKT/HIF-1α signaling22
Effects of myricetin and quercetin on ticagrelor metabolism and the underlying mechanism22
Investigation of the relaxing effect of a camphor nanoemulsion on rat isolated trachea22
Cadmium induces triglyceride levels via microsomal triglyceride transfer protein (MTTP) accumulation caused by lysosomal deacidification regulated by endoplasmic reticulum (ER) Ca2+ homeostasis21
Tubeimoside II inhibits TGF-β1-induced metastatic progression of human retinoblastoma cells through suppressing redoxosome-dependent EGFR activation21
Amygdalin alleviated TGF-β-induced epithelial-mesenchymal transition in bronchial epithelial cells21
TRPC6 is altered in COVID-19 pneumonia21
The influence of alkyl substitution on the in vitro metabolism and mutagenicity of benzo[a]pyrene21
SIRT6 activates PPARα to improve doxorubicin-induced myocardial cell aging and damage21
Novel indole-guanidine hybrids as potential anticancer agents: Design, synthesis and biological evaluation21
Review: Organophosphorus toxicants, in addition to inhibiting acetylcholinesterase activity, make covalent adducts on multiple proteins and promote protein crosslinking into high molecular weight aggr21
Geraniol isolated from lemon grass to mitigate doxorubicin-induced cardiotoxicity through Nrf2 and NF-κB signaling20
Doping gadolinium versus lanthanum into hydroxyapatite particles for better biocompatibility in bone marrow stem cells20
Cytotoxic activity and influence on acetylcholinesterase of series dinuclear platinum(II) complexes with aromatic nitrogen-containing heterocyclic bridging ligands: Insights in the mechanisms of actio20
Morusin inhibits breast cancer-induced osteolysis by decreasing phosphatidylinositol 3-kinase (PI3K)-mTOR signalling20
Plant defence mechanisms against mycotoxin Fumonisin B120
Guttiferones: An insight into occurrence, biosynthesis, and their broad spectrum of pharmacological activities20
Sodium butyrate ameliorates the impairment of synaptic plasticity by inhibiting the neuroinflammation in 5XFAD mice20
Lipopolysaccharide modification enhances the inhibitory effect of clodronate liposomes on hepatic fibrosis by depletion of macrophages and hepatic stellate cells20
Role of phytoconstituents in the management of COVID-1920
Small-molecule MX-C2/3 suppresses non-small cell lung cancer progression via p53 activation19
Fibroblast activation protein alpha: Comprehensive detection methods for drug target and tumor marker19
Selenite induced breast cancer MCF7 cells apoptosis through endoplasmic reticulum stress and oxidative stress pathway19
Ferroptosis is involved in the benzene-induced hematotoxicity in mice via iron metabolism, oxidative stress and NRF2 signaling pathway19
Long-term copper exposure caused hepatocytes autophagy in broiler via miR-455-3p-OXSR1 axis19
Upregulation of Nrf2 signaling and suppression of ferroptosis and NF-κB pathway by leonurine attenuate iron overload-induced hepatotoxicity18
Homogentisic acid, a main phenolic constituent of strawberry tree honey, protects human peripheral blood lymphocytes against irinotecan-induced cytogenetic damage in vitro18
Lauric acid alleviates deoxynivalenol-induced intestinal stem cell damage by potentiating the Akt/mTORC1/S6K1 signaling axis18
Assessments of carbon nanotubes toxicities in zebrafish larvae using multiple physiological and molecular endpoints18
In silico and in vitro antileishmanial effects of gamma-terpinene: Multifunctional modes of action18
Tuberostemonine alleviates high-fat diet-induced obesity and hepatic steatosis by increasing energy consumption18
Chlorquinaldol inhibits the activation of nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing protein 3 inflammasome and ameliorates imiquimod-induced psoriasis-like18
Anticancer effects of oleanolic acid on human melanoma cells18
Exosomal miR-181a-2-3p derived from citreoviridin-treated hepatocytes activates hepatic stellate cells trough inducing mitochondrial calcium overload18
Thymol ameliorates ethanol-induced hepatotoxicity via regulating metabolism and autophagy18
Harnessing the therapeutic potential of fisetin and its nanoparticles: Journey so far and road ahead18
Potential food-drug interaction risk of thymoquinone with warfarin18
Resveratrol inhibits glioblastoma cells and chemoresistance progression through blockade P-glycoprotein and targeting AKT/PTEN signaling pathway18
Cryoprotective isoliquiritigenin-zein phosphatidylcholine nanoparticles inhibits breast cancer-bone metastasis by targeting JAK-STAT signaling pathways17
Oxymatrine inhibits migration and invasion of esophageal squamous cell carcinoma cell lines via the MEK1/ERK/β-catenin pathway17
The role of ALDH1A1 in glioblastoma proliferation and invasion17
Cellular responses following ex vivo lung exposure to the nerve agent VX – Potential for additional treatment targets?17
The assessment of the phototoxic potential of drugs forming complexes with melanin - Screening in vitro studies using normal skin cells with varying pigmentation irradiated by a sunlight simulator17
Oleanolic acid promotes liver regeneration after partial hepatectomy via regulating pregnane X receptor signaling pathway in mice17
Arecoline induces cardiotoxicity by upregulating and activating cardiac hypertrophy-related pathways in Sprague–Dawley rats17
Neuroprotective thiourea derivative uncouples mitochondria and exerts weak protonophoric action on lipid membranes17
EGCG inhibits migration, invasion and epithelial-mesenchymal transition of renal cell carcinoma by activating TFEB-mediated autophagy17
Synthesis of biocompatible nanocrystalline cellulose against folate receptors as a novel carrier for targeted delivery of doxorubicin17
Paracetamol suppresses neutrophilic oxygen radicals through competitive inhibition and scavenging17
Integrated analysis reveals the immunotoxicity mechanism of BPs on human lymphocytes17
Synthesis of glucosamine-selenium compound and evaluation of its oral toxicity and in vitro anti-hepatitis B virus activity17
Mitigation of lens opacification by a functional food in a diabetic rodent model17
Icariin inhibits hypertrophy by regulation of GPER1 and CaMKII/HDAC4/MEF2C signaling crosstalk in ovariectomized mice16
α-Hederin induces human colorectal cancer cells apoptosis through disturbing protein homeostasis16
SERS spectroscopy as a tool for the study of thiopurine drug pharmacokinetics in a model of human B leukemia cells16
Synthesis, characterization, DFT calculation, antioxidant activity, ADMET and molecular docking of thiosemicarbazide derivatives and their Cu (II) complexes16
Catalpol ameliorates endothelial dysfunction and inflammation in diabetic nephropathy via suppression of RAGE/RhoA/ROCK signaling pathway16
Perfluorooctanoic acid induces hepatocellular endoplasmic reticulum stress and mitochondrial-mediated apoptosis in vitro via endoplasmic reticulum-mitochondria communication16
Isovitexin prevents DSS-induced colitis through inhibiting inflammation and preserving intestinal barrier integrity through activating AhR16
Berberine hydrochloride ameliorates PM2.5-induced pulmonary fibrosis in mice through inhibiting oxidative stress and inflammatory16
Novel coumarin-chalcone derivatives: Synthesis, characterization, antioxidant, cyclic voltammetry, molecular modelling and biological evaluation studies as acetylcholinesterase, α-glycosidase, and car16
Nanocarrier design–function relationship: The prodigious role of properties in regulating biocompatibility for drug delivery applications16
Advances in designing of polymeric micelles for biomedical application in brain related diseases16
Development of a conduit of PLGA-gelatin aligned nanofibers produced by electrospinning for peripheral nerve regeneration16
Oleanolic acid induces HCT116 colon cancer cell death through the p38/FOXO3a/Sirt6 pathway16
Research progress of small-molecule drugs in targeting telomerase in human cancer and aging16
Assessment of doxorubicin toxicity using human cardiac organoids: A novel model for evaluating drug cardiotoxicity16
Depleted uranium induces thyroid damage through activation of ER stress via the thrombospondin 1-PERK pathway16
A photoactivatable chemotherapeutic Ru(II) complex bearing bathocuproine ligand efficiently induces cell death in human malignant melanoma cells through a multi-mechanistic pathway16
Drug-drug interaction potentials of tucatinib inhibition of human UDP-glucuronosyltransferases16
Aspirin alleviates cisplatin-induced acute kidney injury through the AMPK-PGC-1α signaling pathway16
Aureusidin ameliorates 6-OHDA-induced neurotoxicity via activating Nrf2/HO-1 signaling pathway and preventing mitochondria-dependent apoptosis pathway in SH-SY5Y cells and Caenorhabditis elegans16
Inhibition of AT1R/IP3/IP3R-mediated Ca2+ release protects against calcium oxalate crystals-induced renal oxidative stress15
Intestinal homeostasis disruption in mice chronically exposed to arsenite-contaminated drinking water15
The selective activator protein-1 inhibitor T-5224 regulates the IRF4/MYC axis and exerts cooperative antimyeloma activity with bortezomib15
Corrigendum to “Discovery and characterization of the flavonoids in Cortex Mori Radicis as naturally occurring inhibitors against intestinal nitroreductases” [Chem. Biol. Interact. 368 (2022) 110222]15
Paraoxonase 1 activity in patients with Alzheimer disease: Systematic review and meta-analysis15
Baicalein ameliorates polymyxin B-induced acute renal injury by inhibiting ferroptosis via regulation of SIRT1/p53 acetylation15
Protective effects of phosphocreatine on human vascular endothelial cells against hydrogen peroxide-induced apoptosis and in the hyperlipidemic rat model15
Modeling of a near-attack conformation of oxime in phosphorylated acetylcholinesterase via a reactivation product, a phosphorylated oxime15
Matrine disrupts Nrf2/GPX4 antioxidant system and promotes hepatocyte ferroptosis15
Indole alkaloids from marine resources: Understandings from therapeutic point of view to treat cancers15
Nanoparticle formulations: A smart era of advanced treatment with nanotoxicological imprints on the human body15
Hormetic effects of EGC and EGCG on CES1 activity and its rescue from oxidative stress in rat liver S915
Benzo[a]pyrene treatment modulates Nrf2/Keap1 axis and changes the metabolic profile in rat lung cancer15
Low levels of endogenous cholinesterases support the choice of cows, sheep and goats for the transgenic expression of human butyrylcholinesterase in milk15
Molybdenum and/or cadmium induce NLRP3 inflammasome production by causing mitochondria-associated endoplasmic reticulum membrane dysfunction in sheep hepatocytes15
Malvidin promotes PGC-1α/Nrf2 signaling to attenuate the inflammatory response and restore mitochondrial activity in septic acute kidney injury15
Discovery of mycotoxin alternariol as a potential lead compound targeting xanthine oxidase14
Muller letter reveals scientific scandal that discredits evidence used to support LNT14
Hydroxylated polymethoxyflavones reduce the activity of pancreatic lipase, inhibit adipogenesis and enhance lipolysis in 3T3-L1 mouse embryonic fibroblast cells14
Gut microbiota contribute to Methamphetamine-induced cardiotoxicity in mouse model14
Protective effect of eicosapentaenoic acid against estradiol valerate-induced endometrial hyperplasia via modulation of NF-κB/HIF-1α/VEGF signaling pathway in rats14
Polystyrene microplastics induce male reproductive toxicity in mice by activating spermatogonium mitochondrial oxidative stress and apoptosis14
Wnt/β-catenin antagonist pyrvinium rescues high dose isoproterenol induced cardiotoxicity in rats: Biochemical and immunohistological evidences14
Ursonic acid from Artemisia montana exerts anti-diabetic effects through anti-glycating properties, and by inhibiting PTP1B and activating the PI3K/Akt signaling pathway in insulin-resistant C2C12 cel14
Molecular determinants of the response of cancer cells towards geldanamycin and its derivatives14
Honokiol and its analogues as anticancer compounds: Current mechanistic insights and structure-activity relationship14
Cyclophosphamide reduces gene transcriptional activity and embryo in vitro development by inhibiting NF-κB expression through decreasing AcH4K1214
Targeting PKD2 aggravates ferritinophagy-mediated ferroptosis via promoting autophagosome-lysosome fusion and enhances efficacy of carboplatin in lung adenocarcinoma14
Alternative splicing affects synapses in the hippocampus of offspring after maternal fructose exposure during gestation and lactation14
(m-CF3-PhSe)2 benefits against anxiety-like phenotype associated with synaptic plasticity impairment and NMDAR-mediated neurotoxicity in young mice exposed to a lifestyle model14
2,3,5,4′-Tetrahydroxy stilbene-2-Ο-β-D-glucoside, a mechanism-based inactivator of CYP2C19 and CYP3A4, potentiates hepatic protein adduction and hepatotoxicity induced by emodin in vivo14
Synthesis, anticancer activity and mechanism of action of new phthalimido-1,3-thiazole derivatives14
Mode of action assessment for propylene dichloride as a human carcinogen14
Interfering TRIB3 protects the blood brain barrier through PI3K/Akt pathway to alleviate cerebral ischemia-reperfusion injury in diabetes mellitus mice14
Baicalin exerts neuroprotective actions by regulating the Nrf2-NLRP3 axis in toxin-induced models of Parkinson's disease14
Inflammation- and cancer-related microRNAs in rat renal cortex after subchronic exposure to fluoride14
In‐vitro antiviral screening of some thiopyranothiazoles14
In-Silico molecular screening of natural compounds as a potential therapeutic inhibitor for Methicillin-resistant Staphylococcus aureus inhibition14
Chemicals of environmental concern as inhibitors of human placental 3β-hydroxysteroid dehydrogenase 1 and aromatase: Screening and docking analysis14
ERO1α primes the ryanodine receptor to respond to arsenite with concentration dependent Ca2+ release sequentially triggering two different mechanisms of ROS formation14
Potent toxic effects of Taroxaz-104 on the replication of SARS-CoV-2 particles13
Baicalein ameliorates cerebral ischemia-reperfusion injury by inhibiting ferroptosis via regulating GPX4/ACSL4/ACSL3 axis13
Control of ER-positive breast cancer by ERα expression inhibition, apoptosis induction, cell cycle arrest using semisynthetic isoeugenol derivatives13
Anti-inflammatory effects of β-ionone-curcumin hybrid derivatives against ulcerative colitis13
Effects of whole-life exposure to low-dose cadmium with post-weaning high-fat diet on offspring testes in a male mouse model13
Empagliflozin alleviates endoplasmic reticulum stress and augments autophagy in rotenone-induced Parkinson's disease in rats: Targeting the GRP78/PERK/eIF2α/CHOP pathway and miR-211-5p13
Arsenic trioxide-induced autophagy affected the antioxidant capacity and apoptosis rate of chicken hepatocytes13
Kaempferol alleviates the inflammatory response and stabilizes the pulmonary vascular endothelial barrier in LPS-induced sepsis through regulating the SphK1/S1P signaling pathway13
Novel trajectories of the NK1R antagonist aprepitant in rotenone-induced Parkinsonism-like symptoms in rats: Involvement of ERK5/KLF4/p62/Nrf2 signaling axis13
Inhibition of sphingosine kinase 1 attenuates LPS-induced acute lung injury by suppressing endothelial cell pyroptosis13
Salidroside: A review of its recent advances in synthetic pathways and pharmacological properties13
Neuropathology and cholinesterase expression in the brains of octogenarians and older13
In vitro and in vivo studies reveal the beneficial effects of chlorogenic acid against ER stress mediated ER-phagy and associated apoptosis in the heart of diabetic rat13
Impact of ultra-small silver nanoparticles of 2 nm (AgNP2) on neutrophil biology: AgNP2 alter the actin cytoskeleton and induce karyorrhexis by a mitogen-activated protein kinase-dependent mechanism i13
Vasorelaxant effect of 5,7,4′- Trihydroxyflavanone (Naringenin) via endothelium dependent, potassium and calcium channels in Sprague Dawley rats: Aortic ring model13
Chlorpyrifos oxon crosslinking of amyloid beta 42 peptides is a new route for generation of self-aggregating amyloidogenic oligomers that promote Alzheimer's disease13
Human cell-based estrogen receptor beta dimerization assay13
Reduction of photoswitched, nitrogen bridged N-acetyl diazocines limits inhibition of 17βHSD3 activity in transfected human embryonic kidney 293 cells13
Enantioselective toxic effects of the novel chiral antifungal agrochemical penthiopyrad in the early life stage of zebrafish (Danio rerio)13
Polystyrene microplastics induce apoptosis via ROS-mediated p53 signaling pathway in zebrafish13
Corrigendum to “Adaptive regulations of Nrf2 alleviates silver nanoparticles-induced oxidative stress-related liver cells injury” [Chemico-Biol. Interact. 369 (2023) 110287]13
Trimetazidine alleviates paclitaxel-induced peripheral neuropathy through modulation of TLR4/p38/NF-κB and klotho protein expression13
STIP1 knockdown suppresses colorectal cancer cell proliferation, migration and invasion by inhibiting STAT3 pathway13
The disruption of blood-brain barrier induced by long-term arsenic exposure is associated with the increase of MMP-9 and MMP-2: The characteristics are similar to those caused by senescence13
d-ribose-mediated glycation of fibrinogen: Role in the induction of adaptive immune response13
Identification and biotin receptor-mediated activity of a novel seleno-biotin compound that inhibits viability of and induces apoptosis in ovarian cancer cells13
Von Willebrand factor: A key glycoprotein involved in thrombo-inflammatory complications of COVID-1913
The SPATA2/CYLD pathway contributes to doxorubicin-induced cardiomyocyte ferroptosis via enhancing ferritinophagy13
HNF4A as a potential target of PFOA and PFOS leading to hepatic steatosis: Integrated molecular docking, molecular dynamic and transcriptomic analyses13
In vitro evaluation of the toxicity mechanisms of two functionalized reduced graphene oxide derivatives12
Detection of a glutathionyl-carbonylated group (GS–CO–) on D-dopachrome tautomerase with preferential binding of GS–CO– to MIF proteins in rat livers damaged by carbon tetrachloride12
Fecal microbiota transplantation and short-chain fatty acids improve learning and memory in fluorosis mice by BDNF-PI3K/AKT pathway12
Characterization of a novel porcine carbonyl reductase activated by glutathione: Relationship to carbonyl reductase 1, 3α/β-hydroxysteroid dehydrogenase and prostaglandin 9-ketoreductase12
Probing the anticancer activities of facial trioxorhenium and tricarbonylrhenium compounds with heterocyclic ligands12
HIF-1α: A potential therapeutic opportunity in renal fibrosis12
Green tea actions on miRNAs expression – An update12
Recalling the reported toxicity assessment of deoxynivalenol, mitigating strategies and its toxicity mechanisms: Comprehensive review12
Discovery and characterization of the flavonoids in Cortex Mori Radicis as naturally occurring inhibitors against intestinal nitroreductases12
Long non-coding RNAs: A double-edged sword in aging kidney and renal disease12
Do the hormetic effects of chlorogenic acid mediate some of the beneficial effects of coffee?12
Modulating SIRT1, Nrf2, and NF-κB signaling pathways by bergenin ameliorates the cadmium-induced nephrotoxicity in rats12
Neuroprotective role of vitamin B12 in streptozotocin-induced type 1 diabetic rats12
Urolithin A attenuates Doxorubicin-induced cardiotoxicity by enhancing PINK1-regulated mitophagy via Ambra112
Inhibition of ER stress using tauroursodeoxycholic acid rescues obesity-evoked cardiac remodeling and contractile anomalies through regulation of ferroptosis12
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