OOIR: Observatory of International Research

Papers

(The H4-Index of Chemico-Biological Interactions is 45. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Editorial Board	963
ER stress-enhanced HMGA2 plays an important role in Cr (VI)-induced glycolysis and inhibited oxidative phosphorylation by targeting the transcription of ATF4	253
The influence of alkyl substitution on the in vitro metabolism and mutagenicity of benzo[a]pyrene	219
Aspirin alleviates cisplatin-induced acute kidney injury through the AMPK-PGC-1α signaling pathway	215
Computational study to find the goat serum albumin (GSA) binding site as A-esterase	190
Editorial Board	133
Potent genotoxicity of phenytoin in adult male C57BL/6J mice, an effect requiring metabolic activation (possibly by Cyp2c enzymes)	132
Retraction notice to “Quinone oxidoreductases in protection against myelogenous hyperplasia and benzene toxicity” [Chem. Biol. Interact. 153–154 (2005) 147–157]	107
Low levels of endogenous cholinesterases support the choice of cows, sheep and goats for the transgenic expression of human butyrylcholinesterase in milk	105
Characterization of a novel porcine carbonyl reductase activated by glutathione: Relationship to carbonyl reductase 1, 3α/β-hydroxysteroid dehydrogenase and prostaglandin 9-ketoreductase	102
F–53B triggers ovarian granulosa cell senescence and ovarian dysfunction by triggering mitochondrial dysfunction	97
Implications of early-life BPS-induced thyroid disruption on adult female reproductive disorders	93
Drug-drug interaction potentials of tucatinib inhibition of human UDP-glucuronosyltransferases	93
Antiviral potential of diminazene aceturate against SARS-CoV-2 proteases using computational and in vitro approaches	92
Inflammatory response and DNA damage induced by dry tobacco exposure in rural workers: A study on complex mixtures and their health impacts	91
In vitro and in vivo anti-inflammatory effects of 5-hydroxyconiferaldehyde via NF-κB, MAPK/AP-1, and Nrf2 modulation	78
Discovery and characterization of the flavonoids in Cortex Mori Radicis as naturally occurring inhibitors against intestinal nitroreductases	78
Corrigendum to “Hepatoprotective effect of anemoside B4 against sepsis-induced acute liver injury through modulating the mTOR/p70S6K-mediated autophagy” [Chem. Biol. Interact. 345 (2021) 109534]	74
Alternative splicing affects synapses in the hippocampus of offspring after maternal fructose exposure during gestation and lactation	71
Selenium binding protein 1 protects renal tubular epithelial cells from ferroptosis by upregulating glutathione peroxidase 4	70
HO-1 activation contributes to cadmium-induced ferroptosis in renal tubular epithelial cells via increasing the labile iron pool and promoting mitochondrial ROS generation	70
BjussuMP-II, a venom metalloproteinase, induces the release and cleavage of pro-inflammatory cytokines and disrupts human umbilical vein endothelial cells	66
Preconception paternal exposure to zearalenone impairs male fertility and IVF embryo survival in mice	65
Equol promotes osteogenic differentiation of hPDLSCs by inhibiting oxidative stress via IL1B/NF-κB/CXCL1 signaling axis	65
Honokiol inhibits interleukin-induced angiogenesis in the NSCLC microenvironment through the NF-κB signaling pathway	64

Chlorquinaldol inhibits the activation of nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing protein 3 inflammasome and ameliorates imiquimod-induced psoriasis-like	62
Thymol ameliorates ethanol-induced hepatotoxicity via regulating metabolism and autophagy	62
Interaction between ethanol and flunitrazepam in rats: Pharmacokinetic mechanisms and toxicological implications	60
Synergistic kidney toxicity of polylactic acid nanoplastics and Cr(VI): Ferroptosis aggravated by mitophagy	58
Anti-inflammatory effects of β-ionone-curcumin hybrid derivatives against ulcerative colitis	57
Copper homeostasis and its dysregulation in diseases: A focus on cuproptosis	55
Modeling of a near-attack conformation of oxime in phosphorylated acetylcholinesterase via a reactivation product, a phosphorylated oxime	54
Metabolic reprogramming by baicalein disrupts fibroblast–macrophage crosstalk in idiopathic pulmonary fibrosis	54
Recalling the reported toxicity assessment of deoxynivalenol, mitigating strategies and its toxicity mechanisms: Comprehensive review	53
Structure-dependent inhibition of human carboxylesterase 1 by organophosphate esters: integrated in vitro profiling and 3D-QSAR interpretation	51
Benzo[a]pyrene treatment modulates Nrf2/Keap1 axis and changes the metabolic profile in rat lung cancer	51
Inhibition of AT1R/IP3/IP3R-mediated Ca2+ release protects against calcium oxalate crystals-induced renal oxidative stress	51
HIF-1α: A potential therapeutic opportunity in renal fibrosis	50
Molecular mechanisms underlying the effects of beta-sitosterol on TGF-β1/Nrf2/SIRT1/p53-mediated signaling in the kidney of a high-fat diet and sucrose-induced type-2 diabetic rat	49
Non-targeting siRNA-mediated responses are associated with apoptosis in chemotherapy-induced senescent skin cancer cells	49
Editorial Board	48
Involvement of esterases in the pulmonary metabolism of beclomethasone dipropionate and the potential influence of cannabis use	48
Solvent isotope and mutagenesis studies on the proton relay system in yeast alcohol dehydrogenase 1	47
Bone–muscle crosstalk following exercise plus Ursolic acid by myomiR-133a/Cx43-Runx2 axis in aged type 2 diabetes rat models	47
Protective effect and mechanism of cannabidiol on myocardial injury in exhaustive exercise training mice	45
Editorial Board	45