OOIR: Observatory of International Research

Papers

(The H4-Index of Chemico-Biological Interactions is 38. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Essential metals in health and disease	338
Nuclear factor-kappa B and its role in inflammatory lung disease	140
Salidroside: A review of its recent advances in synthetic pathways and pharmacological properties	113
Polystyrene microplastics induce apoptosis via ROS-mediated p53 signaling pathway in zebrafish	100
Multifunctional roles and pharmacological potential of β-sitosterol: Emerging evidence toward clinical applications	97
Activation of autophagy and suppression of apoptosis by dapagliflozin attenuates experimental inflammatory bowel disease in rats: Targeting AMPK/mTOR, HMGB1/RAGE and Nrf2/HO-1 pathways	97
Sodium butyrate ameliorates the impairment of synaptic plasticity by inhibiting the neuroinflammation in 5XFAD mice	86
Colon cancer and colorectal cancer: Prevention and treatment by potential natural products	82
Baicalein ameliorates cerebral ischemia-reperfusion injury by inhibiting ferroptosis via regulating GPX4/ACSL4/ACSL3 axis	81
Antioxidant and anti-inflammatory effects of hesperidin methyl chalcone in experimental ulcerative colitis	70
Transforming growth factor-β signaling: From tissue fibrosis to therapeutic opportunities	63
Galangin as an inflammatory response modulator: An updated overview and therapeutic potential	55
Dihydroartemisinin induces pyroptosis by promoting the AIM2/caspase-3/DFNA5 axis in breast cancer cells	54
Rapamycin as a potential repurpose drug candidate for the treatment of COVID-19	53
A review on epidermal growth factor receptor's role in breast and non-small cell lung cancer	52
Exploring the binding mechanism and adverse toxic effects of persistent organic pollutant (dicofol) to human serum albumin: A biophysical, biochemical and computational approach	51
Artesunate induces autophagy dependent apoptosis through upregulating ROS and activating AMPK-mTOR-ULK1 axis in human bladder cancer cells	51
Astaxanthin attenuates osteoarthritis progression via inhibiting ferroptosis and regulating mitochondrial function in chondrocytes	49
In silico analysis of selected alkaloids against main protease (Mpro) of SARS-CoV-2	48
Alcohol consumption and risk of stomach cancer: A meta-analysis	48
Renal damage induced by cadmium and its possible therapy by mitochondrial transplantation	47
2D materials, synthesis, characterization and toxicity: A critical review	47
Chalcones: Promising therapeutic agents targeting key players and signaling pathways regulating the hallmarks of cancer	46
Erythrocytes as model cells for biocompatibility assessment, cytotoxicity screening of xenobiotics and drug delivery	46
Effects of low-level imidacloprid oral exposure on cholinesterase activity, oxidative stress responses, and primary DNA damage in the blood and brain of male Wistar rats	46

Fluoride regulates chondrocyte proliferation and autophagy via PI3K/AKT/mTOR signaling pathway	45
Neuroprotective effects of protocatechuic acid on sodium arsenate induced toxicity in mice: Role of oxidative stress, inflammation, and apoptosis	44
Nuclear factor-κB signaling inhibitors revert multidrug-resistance in breast cancer cells	44
Resveratrol protects against cisplatin-induced ovarian and uterine toxicity in female rats by attenuating oxidative stress, inflammation and apoptosis	44
Aptamer-conjugated carbon-based nanomaterials for cancer and bacteria theranostics: A review	43
Alcohol consumption. A leading risk factor for cancer	43
Asperuloside suppressing oxidative stress and inflammation in DSS-induced chronic colitis and RAW 264.7 macrophages via Nrf2/HO-1 and NF-κB pathways	41
Catalpol ameliorates endothelial dysfunction and inflammation in diabetic nephropathy via suppression of RAGE/RhoA/ROCK signaling pathway	41
Artificial neural networks in contemporary toxicology research	41
2-Pyridone natural products as inhibitors of SARS-CoV-2 main protease	40
Identification of a new class of potent aldose reductase inhibitors: Design, microwave-assisted synthesis, in vitro and in silico evaluation of 2-pyrazolines	39
Polysaccharides from Dendrobium officinale ameliorate colitis-induced lung injury via inhibiting inflammation and oxidative stress	39
Chlorogenic acid abates male reproductive dysfunction in arsenic-exposed mice via attenuation of testicular oxido-inflammatory stress and apoptotic responses	38
Potent toxic effects of Taroxaz-104 on the replication of SARS-CoV-2 particles	38