OOIR: Observatory of International Research

Papers

(The H4-Index of Chemico-Biological Interactions is 36. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Roles of flavonoids against coronavirus infection	233
Essential metals in health and disease	187
Mechanism and regulation of pyroptosis-mediated in cancer cell death	161
High fat diet-triggered non-alcoholic fatty liver disease: A review of proposed mechanisms	118
Nuclear factor-kappa B and its role in inflammatory lung disease	111
The role of reactive oxygen species in the biological activity of antimicrobial agents: An updated mini review	85
Activation of autophagy and suppression of apoptosis by dapagliflozin attenuates experimental inflammatory bowel disease in rats: Targeting AMPK/mTOR, HMGB1/RAGE and Nrf2/HO-1 pathways	84
Salidroside: A review of its recent advances in synthetic pathways and pharmacological properties	77
Polystyrene microplastics induce apoptosis via ROS-mediated p53 signaling pathway in zebrafish	76
Sodium butyrate ameliorates the impairment of synaptic plasticity by inhibiting the neuroinflammation in 5XFAD mice	72
Thymoquinone suppresses invasion and metastasis in bladder cancer cells by reversing EMT through the Wnt/β-catenin signaling pathway	66
Triaryl dicationic DNA minor-groove binders with antioxidant activity display cytotoxicity and induce apoptosis in breast cancer	60
Cytochrome P450 2E1 and its roles in disease	59
Antioxidant and anti-inflammatory effects of hesperidin methyl chalcone in experimental ulcerative colitis	58
Multifunctional roles and pharmacological potential of β-sitosterol: Emerging evidence toward clinical applications	52
Colon cancer and colorectal cancer: Prevention and treatment by potential natural products	51
Baicalein ameliorates cerebral ischemia-reperfusion injury by inhibiting ferroptosis via regulating GPX4/ACSL4/ACSL3 axis	50
Rapamycin as a potential repurpose drug candidate for the treatment of COVID-19	47
Exploring the binding mechanism and adverse toxic effects of persistent organic pollutant (dicofol) to human serum albumin: A biophysical, biochemical and computational approach	46
Perspectives and advancements in the design of nanomaterials for targeted cancer theranostics	45
In silico analysis of selected alkaloids against main protease (Mpro) of SARS-CoV-2	44
Molecular and cellular basis of the anticancer activity of the prenylated flavonoid icaritin in hepatocellular carcinoma	43
Artesunate induces autophagy dependent apoptosis through upregulating ROS and activating AMPK-mTOR-ULK1 axis in human bladder cancer cells	41
Alcohol consumption and risk of stomach cancer: A meta-analysis	40
Modulation of TRPV1 channel function by natural products in the treatment of pain	40

Plants derived therapeutic strategies targeting chronic respiratory diseases: Chemical and immunological perspective	39
Catalpol ameliorates endothelial dysfunction and inflammation in diabetic nephropathy via suppression of RAGE/RhoA/ROCK signaling pathway	39
Transforming growth factor-β signaling: From tissue fibrosis to therapeutic opportunities	39
Dihydroartemisinin induces pyroptosis by promoting the AIM2/caspase-3/DFNA5 axis in breast cancer cells	39
A review on epidermal growth factor receptor's role in breast and non-small cell lung cancer	37
Taxifolin ameliorates iron overload-induced hepatocellular injury: Modulating PI3K/AKT and p38 MAPK signaling, inflammatory response, and hepatocellular regeneration	37
p-Coumaric acid attenuates alcohol exposed hepatic injury through MAPKs, apoptosis and Nrf2 signaling in experimental models	37
Alcohol consumption. A leading risk factor for cancer	37
Neuroprotective effects of protocatechuic acid on sodium arsenate induced toxicity in mice: Role of oxidative stress, inflammation, and apoptosis	37
Erythrocytes as model cells for biocompatibility assessment, cytotoxicity screening of xenobiotics and drug delivery	36
Targeting cell cycle by β-carboline alkaloids in vitro: Novel therapeutic prospects for the treatment of cancer	36