OOIR: Observatory of International Research

Papers

(The H4-Index of Chemico-Biological Interactions is 46. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Editorial Board	1015
ER stress-enhanced HMGA2 plays an important role in Cr (VI)-induced glycolysis and inhibited oxidative phosphorylation by targeting the transcription of ATF4	320
The influence of alkyl substitution on the in vitro metabolism and mutagenicity of benzo[a]pyrene	230
Computational study to find the goat serum albumin (GSA) binding site as A-esterase	228
Editorial Board	203
Retraction notice to “Quinone oxidoreductases in protection against myelogenous hyperplasia and benzene toxicity” [Chem. Biol. Interact. 153–154 (2005) 147–157]	146
Low levels of endogenous cholinesterases support the choice of cows, sheep and goats for the transgenic expression of human butyrylcholinesterase in milk	141
F–53B triggers ovarian granulosa cell senescence and ovarian dysfunction by triggering mitochondrial dysfunction	111
Characterization of a novel porcine carbonyl reductase activated by glutathione: Relationship to carbonyl reductase 1, 3α/β-hydroxysteroid dehydrogenase and prostaglandin 9-ketoreductase	111
Implications of early-life BPS-induced thyroid disruption on adult female reproductive disorders	109
Thymol ameliorates ethanol-induced hepatotoxicity via regulating metabolism and autophagy	107
Synergistic kidney toxicity of polylactic acid nanoplastics and Cr(VI): Ferroptosis aggravated by mitophagy	100
Benzo[a]pyrene treatment modulates Nrf2/Keap1 axis and changes the metabolic profile in rat lung cancer	96
Antiviral potential of diminazene aceturate against SARS-CoV-2 proteases using computational and in vitro approaches	94
Inflammatory response and DNA damage induced by dry tobacco exposure in rural workers: A study on complex mixtures and their health impacts	85
Corrigendum to “Hepatoprotective effect of anemoside B4 against sepsis-induced acute liver injury through modulating the mTOR/p70S6K-mediated autophagy” [Chem. Biol. Interact. 345 (2021) 109534]	82
Alternative splicing affects synapses in the hippocampus of offspring after maternal fructose exposure during gestation and lactation	80
BjussuMP-II, a venom metalloproteinase, induces the release and cleavage of pro-inflammatory cytokines and disrupts human umbilical vein endothelial cells	76
Modeling of a near-attack conformation of oxime in phosphorylated acetylcholinesterase via a reactivation product, a phosphorylated oxime	73
Non-targeting siRNA-mediated responses are associated with apoptosis in chemotherapy-induced senescent skin cancer cells	71
Recalling the reported toxicity assessment of deoxynivalenol, mitigating strategies and its toxicity mechanisms: Comprehensive review	70
Potent genotoxicity of phenytoin in adult male C57BL/6J mice, an effect requiring metabolic activation (possibly by Cyp2c enzymes)	67
Chlorquinaldol inhibits the activation of nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing protein 3 inflammasome and ameliorates imiquimod-induced psoriasis-like	67
Discovery and characterization of the flavonoids in Cortex Mori Radicis as naturally occurring inhibitors against intestinal nitroreductases	66
Anti-inflammatory effects of β-ionone-curcumin hybrid derivatives against ulcerative colitis	64

In vitro and in vivo anti-inflammatory effects of 5-hydroxyconiferaldehyde via NF-κB, MAPK/AP-1, and Nrf2 modulation	62
Aspirin alleviates cisplatin-induced acute kidney injury through the AMPK-PGC-1α signaling pathway	60
Metabolic reprogramming by baicalein disrupts fibroblast–macrophage crosstalk in idiopathic pulmonary fibrosis	60
Structure-dependent inhibition of human carboxylesterase 1 by organophosphate esters: integrated in vitro profiling and 3D-QSAR interpretation	59
Drug-drug interaction potentials of tucatinib inhibition of human UDP-glucuronosyltransferases	58
Differences between human and rat 5α-Reductase 1 inhibition by phenolic disinfectants: Comparative kinetics and binding modes for neurosteroid synthesis	58
Selenium binding protein 1 protects renal tubular epithelial cells from ferroptosis by upregulating glutathione peroxidase 4	56
Preconception paternal exposure to zearalenone impairs male fertility and IVF embryo survival in mice	56
HIF-1α: A potential therapeutic opportunity in renal fibrosis	56
Inhibition of AT1R/IP3/IP3R-mediated Ca2+ release protects against calcium oxalate crystals-induced renal oxidative stress	55
Molecular mechanisms underlying the effects of beta-sitosterol on TGF-β1/Nrf2/SIRT1/p53-mediated signaling in the kidney of a high-fat diet and sucrose-induced type-2 diabetic rat	54
Copper homeostasis and its dysregulation in diseases: A focus on cuproptosis	53
Honokiol inhibits interleukin-induced angiogenesis in the NSCLC microenvironment through the NF-κB signaling pathway	53
Interaction between ethanol and flunitrazepam in rats: Pharmacokinetic mechanisms and toxicological implications	52
HO-1 activation contributes to cadmium-induced ferroptosis in renal tubular epithelial cells via increasing the labile iron pool and promoting mitochondrial ROS generation	50
Equol promotes osteogenic differentiation of hPDLSCs by inhibiting oxidative stress via IL1B/NF-κB/CXCL1 signaling axis	48
Involvement of esterases in the pulmonary metabolism of beclomethasone dipropionate and the potential influence of cannabis use	47
Exposure to polyethylene microplastics induces a male testosterone synthesis disorder via oxidative stress-mediated ferroptosis	47
Diagnosis of drug-induced liver injury in model mice by studying the inhibitory effect of serum components on P450 inhibition assay	46
Editorial Board	46
Editorial Board	46
In memoriam of Professor Eugenio Vilanova	46
Bone–muscle crosstalk following exercise plus Ursolic acid by myomiR-133a/Cx43-Runx2 axis in aged type 2 diabetes rat models	46