Chemical & Pharmaceutical Bulletin

Article	Citations
Production Mechanisms of Black Tea Polyphenols	57
Recent Advances in Drug–Antibody Ratio Determination of Antibody–Drug Conjugates	39
Effect of the Molecularly Imprinted Polymer Component Ratio on Analytical Performance	33
A Comprehensive Review on Ulvan Based Hydrogel and Its Biomedical Applications	26
Design and Synthesis of New CDK2 Inhibitors Containing Thiazolone and Thiazolthione Scafold with Apoptotic Activity	26
The New Delivery Strategy of Albumin Carrier Utilizing the Interaction with Albumin Receptors	24
Arctigenin Triggers Apoptosis and Autophagy <i>via</i> PI3K/Akt/mTOR Inhibition in PC-3M Cells	17
Photoinduced Atom Transfer Radical Addition Reaction of Olefins with α-Bromo Carbonyls	17
Development of Lipid Nanoparticles for the Delivery of Macromolecules Based on the Molecular Design of pH-Sensitive Cationic Lipids	16
Impact of COVID-19 Outbreak on the Long-Range Transport of Common Air Pollutants in KUWAMS	15
Chemical Research on Antitumor Isoquinoline Marine Natural Products and Related Compounds	15
Biomimetic Nanoparticle Drug Delivery Systems to Overcome Biological Barriers for Therapeutic Applications	14
<i>N</i>-Nitrosodimethylamine (NDMA) Formation from Ranitidine Impurities: Possible Root Causes of the Presence of NDMA in Ranitidine Hydrochloride	14
A New Inhibitor of ADAM17 Composed of a Zinc-Binding Dithiol Moiety and a Specificity Pocket-Binding Appendage	12
Theoretical Study on the Mechanism of Spirocyclization in Spiroviolene Biosynthesis	12
Progress in Chiral Stationary Phases Based on Proteins and Glycoproteins	12
Determination of Absolute Purities of Hygroscopic Substances by Quantitative NMR Analysis for the Standardization of Quantitative Reagents in the Japanese Pharmacopoeia (Part 2)	12
A Review on the Phytochemical and Pharmacological Properties of <i>Rosa laevigata</i>: A Medicinal and Edible Plant	11
Cellular Uptake and Transport Characteristics of FL118 Derivatives in Caco-2 Cell Monolayers	11
Absolute Purity Determination of a Hygroscopic Substance, Indocyanine Green, Using Quantitative NMR (qNMR)	11
Imbuing an Old Heterocycle with the Power of Modern Catalysis: An Isoxazolidin-5-one Story	11
Development of Novel Methodology Using Diazo Compounds and Metal Catalysts	11
Thiamine Protects Glioblastoma Cells against Glutamate Toxicity by Suppressing Oxidative/Endoplasmic Reticulum Stress	10
UHPLC/MS and NMR-Based Metabolomic Analysis of Dried Water Extract of Citrus-Type Crude Drugs	10
Discovery of C-9 Modified Berberine Derivatives as Novel Lipid-Lowering Agents	10

Functional Peptides That Target Biomembranes: Design and Modes of Action	10
Chiral Bifunctional Selenide Catalysts for Asymmetric Iodolactonizations	10
A Review on the Foodomics Based on Liquid Chromatography Mass Spectrometry	10
Structure–Activity Relationship of Phytoestrogen Analogs as ERα/β Agonists with Neuroprotective Activities	10
Syntheses and Evaluation of 2- or 3-(<i>N</i>-Cyclicamino)chromone Derivatives as Monoamine Oxidase Inhibitors	9
MiR-509-3p Induces Apoptosis and Affects the Chemosensitivity of Cervical Cancer Cells by Targeting the RAC1/PAK1/LIMK1/Cofilin Pathway	9
Fragment-Based Discovery of Irreversible Covalent Inhibitors of Cysteine Proteases Using Chlorofluoroacetamide Library	9
Synthesis and Evaluation of 2-Hydroxy-1,4-naphthoquinone Derivatives as Potent Antimalarial Agents	9
Structure–Activity Relationship Studies of Antimicrobial Naphthoquinones Derived from Constituents of <i>Tabebuia avellanedae</i>	9
MiR-135a Protects against Myocardial Injury by Targeting TLR4	9
Monitoring Analysis of Perfluoroalkyl Substances and F-53B in Bottled Water, Tea and Juice Samples by LC-MS/MS	8
Environmental Risk Assessment of Active Human Pharmaceutical Ingredients in Urban Rivers in Japan	8
Discovery of DS68702229 as a Potent, Orally Available NAMPT (Nicotinamide Phosphoribosyltransferase) Activator	8
Asymmetric Total Syntheses of Mitragynine, Speciogynine, and 7-Hydroxymitragynine	8
μ-Oxo-Hypervalent-Iodine-Catalyzed Oxidative C–H Amination for Synthesis of Benzolactam Derivatives	8
Evaluating the Sun Protection Factor of Cosmetic Formulations Containing Afzelin	8
Isolation of Three New Diterpenes from <i>Dodonaea viscosa</i>	8
Isolation and Characterization of Neuroprotective Components from Citrus Peel and Their Application as Functional Food	8
C–H▪▪▪S Hydrogen Bonds in Ampicillin and Amoxicillin Crystals Investigated by Sulfur K-Edge X-Ray Absorption Near-Edge Structure Spectroscopy and Single-Crystal X-Ray Structure Analysis	8
Effect of Sample Concentration on Nanoparticle Tracking Analysis of Small Extracellular Vesicles and Liposomes Mimicking the Physicochemical Properties of Exosomes	8
Method to Improve Azo-Compound (AAPH)-Induced Hemolysis of Erythrocytes for Assessing Antioxidant Activity of Lipophilic Compounds	8
Monitoring of Cocrystal Dissociation during the Wet Granulation Process in the Presence of Disintegrants by Using Low-Frequency Raman Spectroscopy	7
Quantitative <sup>31</sup>P-NMR for Purity Determination of Sofosbuvir and Method Validation	7
Hepatoprotective Effects of Phloridzin against Isoniazid-Rifampicin Induced Liver Injury by Regulating CYP450 and Nrf2/HO-1 Pathway in Mice	7
Application of Acoustic Ejection MS System to High-Throughput Screening for SARS-CoV-2 3CL Protease Inhibitors	7
Synthesis and Evaluation of Gallotannin Derivatives as Antioxidants and α-Glucosidase Inhibitors	7
A New Bitterness Evaluation Index Obtained Using the Taste Sensor for 48 Active Pharmaceutical Ingredients of Pediatric Medicines	7
An Update Mini-Review on the Progress of Azanucleoside Analogues	7
Determination of Phenolic Compounds in Beverages by Three-Flow Channel Isocratic HPLC with Electrochemical Detections Using a Column-Switching Technique	7
Secorubenine, a Monoterpenoid Indole Alkaloid Glycoside from <i>Adina rubescens</i>: Isolation, Structure Elucidation, and Enantioselective Total Synthesis	7
Effects of Manufacturing Conditions on Pharmaceutical Properties of Petrolatum Ointment—Distribution of Hydrocarbon—	7
A New Glycosidic Acid, Muricatic Acid D, and Resin Glycosides, Muricatins X and XI, from the Crude Resin Glycoside Fraction of the Seeds of <i>Ipomoea muricata</i>	7
Leonurine Preconditioning Attenuates Ischemic Acute Kidney Injury in Rats by Promoting Nrf2 Nuclear Translocation and Suppressing TLR4/NF-κB Pathway	7
Determination of Mogroside V in Luohanguo Extract for Daily Quality Control Operation Using Relative Molar Sensitivity to Single-Reference Caffeine	7
Highly Sensitive Determination of Amino Acids by LC-MS under Neutral Conditions	7
Synthesis of 4,4-Disubstituted 3,4-Dihydropyrimidin-2(1<i>H</i>)-ones and -thiones, the Corresponding Products of Biginelli Reaction Using Ketone, and Their Antiproliferative Effect on HL-	7
2-Thioxothiazolidin-4-one Analogs as Pan-PIM Kinase Inhibitors	7
Bromine K-Edge X-Ray Absorption Near-Edge Structure Analysis on Hydrobromide-Salt Crystals and the Solid Dispersion of Active Pharmaceutical Ingredients	7
Distribution of Domains Formed by Lateral Packing of Intercellular Lipid in the Stratum Corneum	7
Indole Glycosides from <i>Calanthe discolor</i> with Proliferative Activity on Human Hair Follicle Dermal Papilla Cells	6
Three New C<sub>19</sub>-Diterpenoid Alkaloids from <i>Aconitum novoluridum</i>	6
Flip-Flop Promotion Mechanisms by Model Transmembrane Peptides	6
Importance of the Azole Moiety of Cimetidine Derivatives for the Inhibition of Human Multidrug and Toxin Extrusion Transporter 1 (hMATE1)	6
Chemical Constituents from the Leaves of <i>Pachyrhizus erosus</i> Collected in Vietnam	6
Effects and Mode of Action of Oleic Acid and Tween 80 on Skin Permeation of Disulfiram	6
Structure–Activity Relationships of Thiophene Carboxamide Annonaceous Acetogenin Analogs: Shortening the Alkyl Chain in the Tail Part Significantly Affects Their Growth Inhibitory Activity against Hum	6
Purity Determination of Cyclophosphamide Hydrate by Quantitative <sup>31</sup>P-NMR and Method Validation	6
LC-MS/MS Assay for the Measurement of Cannabidiol Profiling in CBD Oil from Japanese Market and Application for Convertible Tetrahydrocannabinol in Acetic Acid Condition	6
Identification of Phenolic Constituents and Inhibitory Activity of Persimmon Calyx and Shiteito against Tumor Cell Proliferation	6
Synthesis of Non-canonical Amino Acids and Peptide Containing Them for Establishment of the Template for Drug Discovery	6

Substrate Specificity and the Direction of Transport in the ABC Transporters ABCD1–3 and ABCD4	6
Near-Infrared Metabolic Profiling for Discrimination of Apricot and Peach Kernels	6
Biological Synergy and Antimicrobial Mechanism of Hydroxypropyltrimethyl Ammonium Chloride Chitosan with Benzalkonium Chloride	6
Design, Synthesis and Pharmacological Evaluation of Some C<sub>3</sub> Heterocyclic-Substituted Ciprofloxacin Derivatives as Chimeric Antitubercular Agents	6
Structure and Stereochemistry of Amphidinolide N Congeners from Marine Dinoflagellate <i>Amphidinium</i> Species	5
Mechanism of Solubility Enhancement of Poorly Water-Soluble Drugs Triggered by Zeolitic Imidazolate Frameworks	5
Elucidation of Degradation Behavior of Nitrazepam and Other Benzodiazepines in Artificial Gastric Juice: Study on Degradability of Drugs in Stomach (II)	5
Immunochromatography—Application Example and POCT Type Genetic Testing	5
Determination of Mineral Elements in Nanyang Mugwort (<i>Artemisia argyi</i>) Leaves Harvested from Different Crops by Inductively Coupled Plasma Mass Spectrometry and Inductively Coupled	5
Paeonol Pretreatment Attenuates Anoxia-Reoxygenation Induced Injury in Cardiac Myocytes <i>via</i> a BRCA1 Dependent Pathway	5
Improvement of Pharmaceutical Properties of Zerumbone, a Multifunctional Compound, Using Cyclodextrin Derivatives	5
Miroestrol Quantification in <i>Pueraria mirifica</i> Crude Drugs and Products by Single-Reference UPLC/PDA/MS Using Relative Molar Sensitivities to Kwakhurin	5
Sequence-Independent Traceless Method for Preparation of Peptide/Protein Thioesters Using CPaseY-Mediated Hydrazinolysis	5
Discoveries and Syntheses of Highly Potent Antimalarial Troponoids	5
Development of Highly Sensitive Chemiluminescence Enzyme Immunostaining Assay to Determine Glycyrrhizin Content Using Anti-glycyrrhizin Monoclonal Antibody	5
Elaboration of Non-naturally Occurring Helical Tripeptides as p53–MDM2/MDMX Interaction Inhibitors	5
<i>Atractylodes macrocephala</i> Rhizomes Contain Anti-inflammatory Sesquiterpenes	5
Effects of Manufacturing Process Variables on the Tablet Weight Variation of Mini-tablets Clarified by a Definitive Screening Design	5
Emerging Separation Techniques in Supercritical Fluid Chromatography	5
Phase Separation in Lipid Lamellae Result from Ceramide Conformations and Lateral Packing Structure	5
Effect of Disintegrants on Prolongation of Tablet Disintegration Induced by Immersion in Xanthan Gum-Containing Thickening Solution: Contribution of Disintegrant Interactions with Disintegration Fluid	5
Design of the N-Terminus Substituted Curvature-Sensing Peptides That Exhibit Highly Sensitive Detection Ability of Bacterial Extracellular Vesicles	5
Regulatory Roles of N- and C-Terminal Cytoplasmic Regions of P4-ATPases	5
Design, Synthesis and Cytotoxicity Evalufation of Substituted Benzimidazole Conjugated 1,3,4-Oxadiazoles	5
Development of Catalytic Reactions for Precise Control of Chemoselectivity	5
Aryne Generation from <i>o</i>-Triazenylarylboronic Acids Induced by Brønsted Acid	5
Prediction of Anti-proliferation Effect of [1,2,3]Triazolo[4,5-<i>d</i>]pyrimidine Derivatives by Random Forest and Mix-Kernel Function SVM with PSO	5
Application of Quantitative NMR Spectroscopy to the Quality Evaluation of Diclofenac Gargles as Hospital Preparations	5
Design, Synthesis and Activity Evaluation of New Phthalazinone PARP Inhibitors	5
Continuous Monitoring of the Hydration Behavior of Hydrophilic Matrix Tablets Using Time-Domain NMR	5
Molecular Capture and Conformational Change of Diketopiperazines Containing Proline Residues by Epigallocatechin-3-<i>O</i>-gallate in Water	5
An Amphipathic Structure of a Dipropylglycine-Containing Helical Peptide with Sufficient Length Enables Safe and Effective Intracellular siRNA Delivery	5
CBDPS 1.0: A Python GUI Application for Machine Learning Models to Predict Bitter-Tasting Children’s Oral Medicines	5
Design, Synthesis, and Structure–Activity Relationships Study of <i>N</i>-Pyrimidyl/Pyridyl-2-thiazolamine Analogues as Novel Positive Allosteric Modulators of M<sub>3</sub> Mu	4
Four Novel Pharmaceutical Cocrystals of Oxyresveratrol, Including a 2 : 3 Cocrystal with Betaine	4
Large-Scale Isolation of Three <i>O</i>-Methyl Anthocyanins from Bilberry (<i>Vaccinium myrtillus</i> L.) Extract	4
Development of Highly Sensitive Method for Sugar Determination in Herbal Medicine; Application of Monosaccharides and Oligosaccharides in Japanese Angelica Root and Rehmannia Root	4
Formylation Reaction of Amines Using <i>N</i>-Formylcarbazole	4
Effects of Physicochemical Properties of Constituent Ions of Ionic Liquid on Its Permeation through a Silicone Membrane	4
Amino Acids and Their <i>N</i>-Acetylated Derivatives Maintain the Skin’s Barrier Function	4
Novel Cyclohexyl Meroterpenes Produced by Combinatorial Biosynthesis	4
Use of Silicone Membrane Permeation to Assess Thermodynamic Activities of Ionic Liquids and Their Component Cation and Anion	4
Protein Chemical Modification Using Highly Reactive Species and Spatial Control of Catalytic Reactions	4
Construction of <i>N</i>-Heterocycles Fused with a Highly Substituted Benzene Ring by a Benzyne-Mediated Cyclization/Functionalization Cascade Reaction and Its Application to the Total Syn	4
Application of <i>in Silico</i> Technologies for Drug Target Discovery and Pharmacokinetic Analysis	4
Impact of Magnesium Stearate Content: Modeling of Drug Degradation Using a Modified Arrhenius Equation	4
Lipase-Catalyzed Kinetic Resolution of <i>C</i><sub>1</sub>-Symmetric Heterocyclic Biaryls	4
Nitroxyl Radical/Copper-Catalyzed Electrooxidation of Alcohols and Amines at Low Potentials	4
Computational Screening of Inhibitory Compounds for SARS-Cov-2 3CL Protease with a Database Consisting of Approved and Investigational Chemicals	4
Ruthenium-on-Carbon-Catalyzed Facile Solvent-Free Oxidation of Alcohols: Efficient Progress under Solid–Solid (Liquid)–Gas Conditions	4
Uric Acid as a Photosensitizer in the Reaction of Deoxyribonucleosides with UV Light of Wavelength Longer than 300 nm: Identification of Products from 2′-Deoxycytidine	4
Synthesis of New 26,27-Difluoro- and 26,26,27,27-Tetrafluoro-25-hydroxyvitamin D<sub>3</sub>: Effects of Terminal Fluorine Atoms on Biological Activity and Half-life	4
A New 1,2-Naphthoquinone Derivative with Anti-lung Cancer Activity	4
Design, Synthesis and Antitumor Activities of Novel Quinazolinone Derivatives as Potential EGFR Inhibitors	4
The Challenge to Deliver Oxaliplatin (l-OHP) to Solid Tumors: Development of Liposomal l-OHP Formulations	4
Biosynthesis of Bioactive Natural Products Derived from Theonellidae Family Marine Sponges	4
<i>In Vitro</i> and <i>in Silico</i> Studies of Potential Coronavirus-Specific 3C-Like Protease Inhibitors	4
Application of the Functionality Transfer Oligodeoxynucleotide for the Site-Selective Modification of RNA with a Divers Molecule	4
Bovine Serum Albumin Hydrogel Formation: pH Dependence and Rheological Analyses	4
Characterization of Novel Paclitaxel Nanoparticles Prepared by Laser Irradiation	4
Stiffening of Cancer Cell Membranes Is a Key Biophysical Mechanism of Primary and Tertiary Cancer Prevention with Green Tea Polyphenols	4
The Effect of Iontophoresis with and without Electroporation on the Penetration of High Molecular Compounds into the Stratum Corneum	4
Site-Selective α-Alkylation of 1,3-Butanediol Using a Thiophosphoric Acid Hydrogen Atom Transfer Catalyst	4
Characterization of the Salt and Free Base of Active Pharmaceutical Ingredients Based on NMR Relaxometry Measured by Time Domain NMR	4
Development of Nitrolactonization Mediated by Iron(III) Nitrate Nonahydrate	4
Synthesis, α-Glucosidase Inhibitory Activity and Molecular Docking Study of Chalcone Derivatives Bearing a 1<i>H</i>-1,2,3-Triazole Unit	3
Synthesis of Visible-Light–Activated Hypervalent Iodine and Photo-oxidation under Visible Light Irradiation <i>via</i> a Direct S<sub>0</sub>→T<sub>n</sub> Transiti	3
Enthalpy–Entropy Compensation in the Structure-Dependent Effect of Nonsteroidal Anti-inflammatory Drugs on the Aqueous Solubility of Diltiazem	3
Development of Novel Bead Milling Technology with Less Metal Contamination by pH Optimization of the Suspension Medium	3
Computational Study on the Synergic Effect of Brønsted Acid and Hydrogen-Bonding Catalysis for the Dearomatization Reaction of Phenols with Diazo Functionality	3
Crotofolane-Type Diterpenoids: Crotocascarins R–V, Rearranged Trinorcrotofolane: Crotocascarin δ and a Phorbol Derivative from the Leaves of <i>Croton cascarilloides</i>	3
Synthesis and Evaluation of a Paclitaxel-Binding Tripeptide Micelle for Lung Cancer Therapy	3
Identification of the Inhibitory Compounds for Metallo-β-lactamases and Structural Analysis of the Binding Modes	3
Identification of a Histone Deacetylase 8 Inhibitor through Drug Screenings Based on Machine Learning	3
Tetracyclic Triterpenoids, Steroids and Lignanes from the Aerial Parts of <i>Oxypetalum caeruleum</i>	3
Development of Transition-Metal-Catalyzed Dearomatization Reactions	3
A Fluorescence Biosensor for Tyrosinase Activity Analysis Based on Silicon-Doped Carbon Quantum Dots	3
Development of a Logic Model for Promoting Incorporation of the Concepts of Impurity-Related ICH Guidelines into Pharmacopoeias Based on Cause and Effect Analysis	3
Formation of pH-Responsive Supramolecular Hydrogels in Basic Buffers: Self-assembly of Amphiphilic Tris-Urea	3
Efficiency of Lithium Cations in Hydrolysis Reactions of Esters in Aqueous Tetrahydrofuran	3

Drug-Tea Polyphenol Interaction (III) Incompatibility between Aripiprazole Oral Solution and Green Tea	3
Fragment Molecular Orbital Based Affinity Prediction toward Pyruvate Dehydrogenase Kinases: Insights into the Charge Transfer in Hydrogen Bond Networks	3
Manufacturability and Properties of Granules and Tablets Using the Eco-Friendly Granulation Method Green Fluidized Bed Granulation Compared to Direct Compression	3
Synthesis and Evaluation of Habiterpenol Analogs	3
Research Progress on the Mechanism of Reducing Toxicity and Increasing the Efficacy of Sini Decoction Compatibility	3
Study on the Synthesis of Methylated Reference and Their Application in the Quantity of Curcuminoids Using Single Reference Liquid Chromatography Based on Relative Molar Sensitivity	3
Synthesis and Anti-dengue Virus Activity of 5-Ethynylimidazole-4-carboxamide (EICA) Nucleotide Prodrugs	3
Bioequivalence Dissolution Test Criteria for Formulation Development of High Solubility-Low Permeability Drugs	3
Development of an Antigen Delivery System for a B Cell-Targeted Vaccine as an Alternative to Dendritic Cell-Targeted Vaccines	3
Site-Selective Molecular Transformation: Acylation of Hydroxy Groups and C–H Amination	3
Chemical Constituents from the Branches and Leaves of <i>Alchornea trewioides</i>	3
Effects of Membrane Cholesterol on Stability of Transmembrane Helix Associations	3
Transport Characteristics of Placenta-Derived Extracellular Vesicles and Their Relevance to Placenta-to-Maternal Tissue Communication	3
Development and Validation of an LC–MS/MS-Based Method for Quantifying Urinary Endogenous 6-Hydroxymelatonin	3
Determination of Hardness of a Pharmaceutical Oral Jelly by Using <i>T</i><sub>2</sub> Relaxation Behavior Measured by Time-Domain NMR	3
Gummi Formulations Comprising Amenamevir Solid Dispersions with Polyvinyl Alcohol	3
Preparation of Novel Functional Drug Particles Embedded in a Gelling–Swelling Layer (PEGS) for Taste Masking and Subsequent Rapid Drug Release	3
Liquiritigenin Attenuated Collagen-Induced Arthritis and Cardiac Complication <i>via</i> Inflammation and Fibrosis Inhibition in Mice	3
Improvement of Skin Permeation of Caffeine, a Hydrophilic Drug, by the Application of Water Droplets Provided by a Novel Humidifier Device	3
Synthesis and Formation Mechanism of a Compound with an Unprecedented Skeleton: Dodecahydro-4,10:5,9-diepoxydipyrrolo[3,4-<i>b</i>:3′,4′-<i>f</i>][1,5]diazocine	3
Approach to Establishment of Control Strategy for Oral Solid Dosage Forms Using Continuous Manufacturing	3
A Facile Method to Determine Prolidase Activity Using a Peptide-Specific Fluorometric Reaction	3
Inhibition of Acetylcholinesterase by Wood Creosote and Simple Phenolic Compounds	3
Synthesis and Evaluation of a Novel Series of 2,7-Substituted-6-tetrazolyl-1,2,3,4-tetrahydroisoquinoline Derivatives as Selective Peroxisome Proliferator-Activated Receptor γ Partial Agonists	3
<sup>1</sup>H-NMR-Based Metabolomics for the Classification of the Roots of <i>Paeonia lactiflora</i>, a Constituent of Kampo Medicines	3
Bivalent β-Carbolines Inhibit Colorectal Cancer Growth through Inducing Autophagy	3
Characteristics of Raw and Acid-Activated Bentonite and Its Application for Improving Electrical Conductivity of Tap Water	3
Shanpanootols G and H, Diterpenoids from the Rhizomes of <i>Kaempferia pulchra</i> Collected in Myanmar and Their Vpr Inhibitory Activities	3
Design, Synthesis and Biological Evaluation of Novel 4-(4-Methoxynaphthalen-1-yl)-5-arylpyrimidin-2-amines as Tubulin Polymerization Inhibitors	3
Chemical Components in <i>Hedera rhombea</i> Leaves and Their Cytotoxicity	3
Symplocosins C–P: Fourteen Triterpene Saponins from the Leaves of <i>Symplocos cochinchinensis</i> var. <i>philippinensis</i>	3
Concise Syntheses of Violaceoids A and C	3
Synthesis of Chloro-Substituted 6<i>H</i>-Dibenzo[<i>b</i>,<i>d</i>]pyran-6-one Natural Products, Graphislactone G, and Palmariols A and B	3
Design, Synthesis and Structure–Activity Relationship Studies of Protein Kinase CK2 Inhibitors Containing a Purine Scaffold	3
Influence of Purification Process on the Function of Synthetic Polymer Nanoparticles	3
Antiproliferative Effect of <i>N</i>-Heterocyclo-Coumarin Derivatives against Multidrug-Resistant Cells	3
Pyrrolactams from Marine Sponge <i>Stylissa massa</i> Collected from Myanmar and Their Anti-Vpr Activities	3
Electrophilic Epoxidation of α,β-Unsaturated Oximes with Dioxiranes and Ring Opening of the Epoxides	3
Protective Effect of Apple Polyphenols on H<sub>2</sub>O<sub>2</sub>-Induced Oxidative Stress Damage in Human Colon Adenocarcinoma Caco-2 Cells	3
Evaluation of the Effect of Disintegrant Distribution on the Dissolution Behavior of Pharmaceutical Tablets Using Raman Chemical Imaging	3
An Ornithine-Free Gramicidin S Analogue Using Norleucine, Cyclo(Val–Nle–Leu–D-Phe–Pro)<sub>2</sub>, Forms Helically Aligned β-Sheets	2
Topical Formulations of Propranolol for Infantile Hemangiomas: Characteristics of Formulations and Three Cases of Infants Administered Topical Propranolol Cream	2
Direct <i>N</i><sup>1</sup>-Selective Alkylation of Hydantoins Using Potassium Bases	2
Rational Design of Amphipathic Antimicrobial Peptides with Alternating L-/D-Amino Acids That Form Helical Structures	2
Advanced Formulation Design for Topical Creams Assisted with Vibrational Spectroscopic Imaging	2
Formulation of Biopharmaceutical Dry Powder Inhaler Using the Void Forming Index (VFI) to Detect and Avoid Powder Caking in Dry Powder Inhaler Formulations	2
Effects of Substituting Disubstituted Amino Acids into the Amphipathic Cell Penetrating Peptide Pep-1	2
Characterization of Tableting Speed-Dependent Deformation Properties of Active Pharmaceutical Ingredients in Powder Mixtures Using Out-of-Die Method	2
Separation and Identification of Isoleucine Enantiomers and Diastereomers Using an Original Chiral Resolution Labeling Reagent	2
Masking the Taste of Fixed-Dose Combination Drugs: Particular NSAIDs Can Efficiently Mask the Bitterness of Famotidine	2
Numerical Study on Spray Drying Process: Effect of Nonuniform Temperature Field and Interaction between Droplets on Evaporation Rates of Individual Droplets	2
Theoretical Study of the Mechanism of Ribosomal Peptide Bond Formation Using the ONIOM Method	2
Four New Pregnane-10,2-carbolactones from an <i>Epipolasis</i> sp. Marine Sponge	2
Advanced Solid-State NMR Analysis of Two Crystal Forms of Ranitidine Hydrochloride: Detection of <sup>1</sup>H–<sup>14</sup>N Intra-/Intermolecular Correlations	2
Comparative Study of General Notices in Pharmacopoeias in Japan, the United States, and Europe	2
Elucidation of Degradation Behavior of Hydroxy Group-Containing Benzodiazepines in Artificial Gastric Juice: Study on Degradability of Drugs in Stomach (III)	2
Engineered Biosynthesis of Pharmaceutically Important Compounds	2
A Novel Amphotericin B Hydrogel Composed of Poly(Vinyl Alcohol)/Borate Complex for Ophthalmic Formulation	2
Halichonic Acid B, a Rearranged Nitrogenous Bisabolene-Type Sesquiterpene from a Marine Sponge <i>Axinyssa</i> sp.	2
Effect of the Physicochemical Properties of Liquid Paraffin on the Phase State and Rheological Properties of Lecithin Reverse Wormlike Micelles	2
Syntheses of Aryl Thioethers <i>via</i> Aromatic Substitution of Aryl Halides at 0 to 25 °C	2
Characterization of Ambroxol and Its Hydrochloride Salt Crystals by Bromine K-Edge X-Ray Absorption Near-Edge Structure Spectroscopy and X-Ray Crystal Structure Analysis	2
Structure–Activity Relationships of UTX-121 Derivatives for the Development of Novel Matrix Metalloproteinase-2/9 Inhibitors	2
Advances in Understanding the Mechanism of Ophthalmic Viscosurgical Device Retention in the Anterior Chamber or on the Corneal Surface during Ocular Surgery	2
Identification of a Functionally Efficient and Thermally Stable Outward Sodium-Pumping Rhodopsin (<i>Be</i>NaR) from a Thermophilic Bacterium	2
Selection of Small Amounts of Glidant Capable of Improving the Tensile Strength of Ibuprofen Tablets	2
Antiproliferative Activities of Cynaropicrin and Related Compounds against Cancer Stem Cells	2
Characterization of Ibuprofen-Loaded MgO by One-Step Mid- and Far-FT-IR Spectroscopy	2
Method Development and Validation for Simultaneous Determination of Six Flavonoids in Rat Eyes after Oral Administration of <i>Diospyros kaki</i> Leaves Extract by UPLC-MS/MS	2
Copper-Catalyzed Aerobic C(<i>sp</i><sup>3</sup>)–H Oxidation of β-(Alkoxy)imino Carbonyl Compounds	2
The Inhibitory Effect of Adenylic Acid on the Bitterness of the Antibacterial Combination Drug Trimethoprim/Sulfamethoxazole	2
Pharmaceutical Food Science: Search for Bio-Functional Molecules Obtained from Natural Resources to Prevent and Ameliorate Lifestyle Diseases	2
Effect of Iontophoresis on the Intradermal Migration Rate of Medium Molecular Weight Drugs	2
Enhancing Anticancer Potency of a 13-Substituted Berberine Derivative with Cationic Liposomes	2
Fluorescent-Oxaboroles: Synthesis and Optical Property by Sugar Recognition	2
Natural Compounds with BMI1 Promoter Inhibitory Activity from <i>Mammea siamensis</i> and <i>Andrographis paniculata</i>	2
Chemical Constituents of the Leaves of <i>Thujopsis dolabrata</i> and Their Cytotoxicity	2
Species Difference in the Metabolism of Mulberrin <i>in Vitro</i> and Its Inhibitory Effect on Cytochrome P450 and UDP-Glucuronosyltransferase Enzymes	2
Design, Synthesis and Antibacterial Activities of Novel Amide Derivatives Bearing Dioxygenated Rings as Potential β-Ketoacyl-acyl Carrier Protein Synthase III (FabH) Inhibitors	2
Targeted Therapy for Prostate Cancer by Prostate-Specific Membrane Antigen-Targeted Small-Molecule Drug Conjugates	2
Potential Interaction between Sodium Polystyrene Sulfonate and Prescription Drugs in Artificial Intestinal Juice	2
Construction of 7-Diethylaminocoumarins Promoted by an Electron-Withdrawing Group	2
Cyclopsammocinamides A and B, Enantiomeric Cyclic Peptides of Cyclocinamide A, from the Marine Sponge <i>Psammocinia</i> sp.	2
Modulating Wnt/β-Catenin Signaling Pathway on U251 and T98G Glioblastoma Cell Lines Using a Combination of Paclitaxel and Temozolomide, A Molecular Docking Simulations and Gene Expression Study	2
Discovery of Indole-Piperazine Hybrid Structures as Potent Selective Class I Histone Deacetylases Inhibitors	2
Development of Bitter-Taste Masked Instant Jelly Formulations of Diphenhydramine Hydrochloride with Easy-to-Consume Granules	2
A Facile α-Glucuronidation Using Methyl 1,2,3,4-Tetra-<i>O</i>-acetyl-D-glucuronate as Glycosyl Donor	2
Cocrystallization of Active Pharmaceutical Ingredients Derived from Traditional Chinese Medicines	2
Expansion of Substrate Scope for Nitroxyl Radical/Copper-Catalyzed Aerobic Oxidation of Primary Alcohols: A Guideline for Catalyst Selection	2
Development of Spray Formulations Applied to the Oral Mucosa Using Non-lamellar Liquid Crystal-Forming Lipids	2
Gray-box Soft Sensor for Water Content Monitoring in Fluidized Bed Granulation	2
Structural, Theoretical Analysis, and Molecular Docking of Two Benzamide Isomers. Halogen Bonding and Its Role in the Diverse Ways of Coupling with Protein Residues	2
Target Protein-Oriented Isolations for Bioactive Natural Products	2
Development of Scaled-Up Synthetic Method for Retinoid X Receptor Agonist NEt-3IB Contributing to Sustainable Development Goals	2
CTRP12 Alleviates Isoproterenol Induced Cardiac Fibrosis <i>via</i> Inhibiting the Activation of P38 Pathway	2