Cellular Immunology

Article	Citations
IL-6 as a major regulator of MDSC activity and possible target for cancer immunotherapy	168
The exosomes derived from CAR-T cell efficiently target mesothelin and reduce triple-negative breast cancer growth	101
Galectin-9 as a biomarker of disease severity	73
Regulation of ROS in myeloid-derived suppressor cells through targeting fatty acid transport protein 2 enhanced anti-PD-L1 tumor immunotherapy	70
Role of orally induced regulatory T cells in immunotherapy and tolerance	54
Building a CAR-Treg: Going from the basic to the luxury model	48
Engineered regulatory T cells expressing myelin-specific chimeric antigen receptors suppress EAE progression	44
MDSCs in liver cancer: A critical tumor-promoting player and a potential therapeutic target	42
Myeloid-derived suppressor cells (MDSC): When good intentions go awry	41
Radiotherapy and cGAS/STING signaling: Impact on MDSCs in the tumor microenvironment	40
MDSCs, ageing and inflammageing	34
Sex differences in EAE reveal common and distinct cellular and molecular components	32
STING agonist and IDO inhibitor combination therapy inhibits tumor progression in murine models of colorectal cancer	30
MS4A1 expression and function in T cells in the colorectal cancer tumor microenvironment	29
Human and murine memory γδ T cells: Evidence for acquired immune memory in bacterial and viral infections and autoimmunity	28
Effects of vitamin D on macrophages and myeloid-derived suppressor cells (MDSCs) hyperinflammatory response in the lungs of COVID-19 patients	28
Functional responsiveness of memory T cells from COVID-19 patients	27
Resveratrol attenuates TNBC lung metastasis by down-regulating PD-1 expression on pulmonary T cells and converting macrophages to M1 phenotype in a murine tumor model	26
SIRT1 induces the accumulation of TAMs at colorectal cancer tumor sites via the CXCR4/CXCL12 axis	26
CD8+ T cells: The past and future of immune regulation	24
Blockade of TLRs-triggered macrophage activation by caffeic acid exerted protective effects on experimental ulcerative colitis	23
Towards antigen-specific Tregs for type 1 diabetes: Construction and functional assessment of pancreatic endocrine marker, HPi2-based chimeric antigen receptor	23
CD4+ T cells engineered with FVIII-CAR and murine Foxp3 suppress anti-factor VIII immune responses in hemophilia a mice	22
SARS-CoV-2 peptides bind to NKG2D and increase NK cell activity	22
Sex differences in M2 polarization, chemokine and IL-4 receptors in monocytes and macrophages from asthmatics	22

Roles of the tissue-type plasminogen activator in immune response	21
The role of the BTLA-HVEM complex in the pathogenesis of autoimmune diseases	21
Neutrophil recruitment mediated by sphingosine 1-phosphate (S1P)/S1P receptors during chronic liver injury	21
Regulating the regulators: Is introduction of an antigen-specific approach in regulatory T cells the next step to treat autoimmunity?	21
Molecular cargo in myeloid-derived suppressor cells and their exosomes	21
Lipid metabolism in asthma: Immune regulation and potential therapeutic target	21
CD36 regulates LPS-induced acute lung injury by promoting macrophages M1 polarization	21
Interleukin 27 as an inducer of antiviral response against chikungunya virus infection in human macrophages	20
Schwann cells promote lung cancer proliferation by promoting the M2 polarization of macrophages	19
Rapamycin facilitates differentiation of regulatory T cells via enhancement of oxidative phosphorylation	19
Importance of myeloid derived suppressor cells in cancer from a biomarker perspective	19
Distinct roles of ICOS and CD40L in human T-B cell adhesion and antibody production	17
C C chemokine receptor 5 antagonist alleviates inflammation by regulating IFN-γ/IL-10 and STAT4/Smad3 signaling in a mouse model of autoimmune encephalomyelitis	17
Exploration of the effect of mixed probiotics on microbiota of allergic asthma mice	17
MiR-1294 suppresses ROS-dependent inflammatory response in atopic dermatitis via restraining STAT3/NF-κB pathway	17
Overexpression of DAPK1-mediated inhibition of IKKβ/CSN5/PD-L1 axis enhances natural killer cell killing ability and inhibits tumor immune evasion in gastric cancer	16
Type 1 helper T cells generate CXCL9/10-producing T-bet+ effector B cells potentially involved in the pathogenesis of rheumatoid arthritis	16
Stem cell-like memory T cells: A perspective from the dark side	16
Identification, selection, and expansion of non-gene modified alloantigen-reactive Tregs for clinical therapeutic use	16
Myeloid-derived suppressor cells as cellular immunotherapy in transplantation and autoimmune diseases	16
Epigallocatechin-3 gallate regulates macrophage subtypes and immunometabolism to ameliorate experimental autoimmune encephalomyelitis	16
Lck signaling inhibition causes improvement in clinical features of psoriatic inflammation through reduction in inflammatory cytokines in CD4+ T cells in imiquimod mouse model	16
Roxithromycin inhibits compound 48/80-induced pseudo-allergy via the MrgprX2 pathway both in vitro and in vivo	16
Understanding natural killer cell biology from a single cell perspective	16
Consequences and mechanisms of myelin debris uptake and processing by cells in the central nervous system	16
The lncRNA PVT1 regulates autophagy in regulatory T cells to suppress heart transplant rejection in mice by targeting miR-146a	15
The receptor for advanced glycation endproducts (RAGE) decreases survival of tumor-bearing mice by enhancing the generation of lung metastasis-associated myeloid-derived suppressor cells	15
The hepatic microenvironment and regulatory T cells	15
A transgene-encoded truncated human epidermal growth factor receptor for depletion of anti- B-cell maturation antigen CAR-T cells	15
Application of mesenchymal stem cell-derived exosomes in kidney diseases	15
Tissue-resident macrophage inflammaging aggravates homeostasis dysregulation in age-related diseases	15
Regulation of humoral immune response by HIF-1α-dependent metabolic reprogramming of the germinal center reaction	15
Development, phenotypes of immune cells in BTBR TItpr3/J mice	15
Long non-coding RNA GAS5 regulates Th17/Treg imbalance in childhood pneumonia by targeting miR-217/STAT5	14
Genomic, proteomic, and systems biology approaches in biomarker discovery for multiple sclerosis	14
Effects of omalizumab on basophils: Potential biomarkers in asthma and chronic spontaneous urticaria	14
Lactic acid suppresses MRGPRX2 mediated mast cell responses	14
Down-regulation of LncRNA 2900052N01Rik inhibits LPS-induced B cell function in vitro	13
Modulating glutamine metabolism to control viral immuno-inflammatory lesions	13
Activated mesangial cells acquire the function of antigen presentation	13
Human splenic myeloid derived suppressor cells: Phenotypic and clustering analysis	13
The role of PAK4 in the immune system and its potential implication in cancer immunotherapy	12
Lipid metabolism and neutrophil function	12
Gene polymorphisms of LGALS2, LGALS3 and LGALS9 in patients with rheumatoid arthritis	12
Age-associated B cells indicate disease activity in rheumatoid arthritis	12
Exosomal miR-27a-3p derived from tumor-associated macrophage suppresses propranolol sensitivity in infantile hemangioma	12
Comparing thermal stress reduction strategies that influence MDSC accumulation in tumor bearing mice	12
G-CSF promotes alloregulatory function of MDSCs through a c-Kit dependent mechanism	12
Modulation of PD-1/PD-L1 axis in myeloid-derived suppressor cells by anti-cancer treatments	12
Tumor-related stress regulates functional plasticity of MDSCs	11

Causal link between immunoglobulin G glycosylation and cancer: A potential glycobiomarker for early tumor detection	11
Tumor-infiltrating neutrophils and peripheral neutrophil-to-lymphocyte ratio conversely predicted the prognosis of patients with non-small cell lung cancer	11
Targeting of myeloid-derived suppressor cells by all-trans retinoic acid as host-directed therapy for human tuberculosis	11
Extracellular vesicles released by myeloid-derived suppressor cells from pregnant women modulate adaptive immune responses	11
Cellular uptake and anti-inflammatory effects of palm oil-derived delta (δ)-tocotrienol in microglia	11
Loss of HLA-class-I expression in non-small-cell lung cancer: Association with prognosis and anaerobic metabolism	10
MicroRNA-26b-5p alleviates murine collagen-induced arthritis by modulating Th17 cell plasticity	10
Par3 regulates the asymmetric division of basal stem cells in psoriasis via the Par3/mInsc/LGN signaling axis	10
Differential recognition and cytokine induction by the peptidorhamnomannan from Sporothrix brasiliensis and S. Schenckii	10
The role of sirtuin 1 on the induction of trained immunity	10
The diverse roles of myeloid derived suppressor cells in mucosal immunity	10
In vitro 2D and 3D cancer models to evaluate compounds that modulate macrophage polarization	10
Mast cells modulate early responses to Mycobacterium bovis Bacillus Calmette-Guerin by phagocytosis and formation of extracellular traps	10
Sorted B cell transcriptomes point towards actively regulated B cell responses during ongoing chronic hepatitis B infections	10
Potential therapeutic effect of low-dose paclitaxel in melanoma patients resistant to immune checkpoint blockade: A pilot study	10
Mechanism of taurine reducing inflammation and organ injury in sepsis mice	10
MiR-451a enhances the phagocytosis and affects both M1 and M2 polarization in macrophages	10
Th1 polarization in the tumor microenvironment upregulates the myeloid-derived suppressor-like function of macrophages	10
Rubicon promotes the M2 polarization of Kupffer cells via LC3-associated phagocytosis-mediated clearance to improve liver transplantation	9
Immune system changes in those with hypertension when infected with SARS-CoV-2	9
IL-33 priming amplifies ATP-mediated mast cell cytokine production	9
Deciphering the role of calcium homeostasis in T cells functions during mycobacterial infection	9
HDAC1 potentiates CD4 + T cell activation by inhibiting miR-124 and promoting IRF1 in systemic lupus erythematosus	9
DIM mitigates the development of experimental autoimmune encephalomyelitis by maintaining the stability and suppressive function of regulatory T cells	9
A novel missense mutation in TNFAIP3 causes haploinsufficiency of A20	9
CRISPR/Cas9-mediated demethylation of FOXP3-TSDR toward Treg-characteristic programming of Jurkat T cells	9
Gram-positive Staphylococcus aureus LTA promotes distinct memory-like effects in murine bone marrow neutrophils	8
Monocytic myeloid-derived suppressor cells home to tumor-draining lymph nodes via CCR2 and locally modulate the immune response	8
Neutrophil extracellular traps: Modulation mechanisms by pathogens	8
Type 1 and 2 diabetes are associated with reduced natural killer cell cytotoxicity	8
Evaluation of autophagy mediators in myeloid-derived suppressor cells during human tuberculosis	8
Full-length IL-33 regulates Smad3 phosphorylation and gene transcription in a distinctive AP2-dependent manner	8
Early-life infection of the airways with Streptococcus pneumoniae exacerbates HDM-induced asthma in a murine model	8
Oral tolerance and oral immunotherapy for food allergy: Evidence for common mechanisms?	8
Muscone promotes functional recovery by facilitating microglia polarization into M2 phenotype through PPAR-γ pathway after ischemic stroke	8
Tandem CAR-T cells targeting MUC1 and PSCA combined with anti-PD-1 antibody exhibit potent preclinical activity against non-small cell lung cancer	7
Multiple genetic programs contribute to CD4 T cell memory differentiation and longevity by maintaining T cell quiescence	7
Reactive myelopoiesis and the onset of myeloid-mediated immune suppression: Implications for adoptive cell therapy	7
Macrophages in intestinal fibrosis and regression	7
Mucosal-Associated Invariant T cells exhibit distinct functional signatures associated with protection against typhoid fever	7
Expression regulation and function of PD-1 and PD-L1 in T lymphoma cells	7
Dose-dependent immunomodulatory effects of metformin on human neonatal monocyte-derived macrophages	7
Maternal immune factors involved in the prevention or facilitation of neonatal bacterial infections	7
The impact of MDSCs on the efficacy of preventive and therapeutic HIV vaccines	7
Genetical engineering for NK and T cell immunotherapy with CRISPR/Cas9 technology: Implications and challenges	7
The impact of TLR7 agonist R848 treatment on mast cell phenotype and activity	7
Artemisinin derivative TPN10466 suppresses immune cell migration and Th1/Th17 differentiation to ameliorate disease severity in experimental autoimmune encephalomyelitis	7
IFN-γ+ CD4+T cell-driven prophylactic potential of recombinant LDBPK_252400 hypothetical protein of Leishmania donovani against visceral leishmaniasis	7
Age-related changes in PD-1 expression coincide with increased cytotoxic potential in Vδ2 T cells during infancy	7
Manipulating the microbiome to enhance oral tolerance in food allergy	7
Evaluation of mechanisms of action of re-purposed drugs for treatment of COVID-19	7
TNF contributes to T-cell exhaustion in chronic L. mexicana infections of mice through PD-L1 up-regulation	7
The ERM protein moesin regulates natural killer cell homeostasis in vivo	7
d-mannose administration improves autoimmune hepatitis by upregulating regulatory T cells	7
Usefulness of IL-21, IL-7, and IL-15 conditioned media for expansion of antigen-specific CD8+ T cells from healthy donor-PBMCs suitable for immunotherapy	7
FGFR1 promotes tumor immune evasion via YAP-mediated PD-L1 expression upregulation in lung squamous cell carcinoma	7
Soluble PD-1 (sPD-1) is expressed in human macrophages	7
Fine particulate matter (PM2.5) induces inhibitory memory alveolar macrophages through the AhR/IL-33 pathway	7
Neutrophils in the tumor microenvironment and their functional modulation by mesenchymal stromal cells	6
IRF8 and BATF3 interaction enhances the cDC1 specific Pfkfb3 gene expression	6
Cytomegalovirus specific polyfunctional T-cell responses expressing CD107a predict control of CMV infection after liver transplantation	6
Itaconate indirectly influences expansion of effector T cells following vaccination with Francisella tularensis live vaccine strain	6
Regulatory network of BLIMP1, IRF4, and XBP1 triad in plasmacytic differentiation and multiple myeloma pathogenesis	6
Neutralization of IL-17 and treatment with IL-2 protects septic arthritis by regulating free radical production and antioxidant enzymes in Th17 and Tregs: An immunomodulatory TLR2 versus TNFR response	6
IL-3 Expands Pre-Basophil and Mast Cell Progenitors by Upregulating the IL-3 Receptor Expression	6
Targeting immunosuppressor cells with nanoparticles in autoimmunity: How far have we come to?	6
Lnc-17Rik promotes the immunosuppressive function of Myeloid-Derived suppressive cells in esophageal cancer	6
Trichinella spiralis excretory-secretory antigens selectively inhibit the release of extracellular traps from neutrophils without affecting their additional antimicrobial functions	6
Tumor-associated macrophages mediate gastrointestinal stromal tumor cell metastasis through CXCL2/CXCR2	6
Residual immune activation in HIV-Infected individuals expands monocytic-myeloid derived suppressor cells	6
Repeated exposure to inactivated Streptococcus pneumoniae induces asthma-like pathological changes in mice in the presence of IL-33	6
An unmet need: Harmonization of IL-7 and IL-15 combination for the ex vivo generation of minimally differentiated T cells	6
The splicing factor SRSF1 stabilizes the mRNA of TSLP to enhance acute lung injury	6
VISTA as a ligand downregulates LPS-mediated inflammation in macrophages and neutrophils	6
Neutrophils, functions beyond host defense	6
Role of formyl peptide receptor 2 (FPR2) in modulating immune response and heart inflammation in an experimental model of acute and chronic Chagas disease	6
Role of Suppressor of cytokine signaling 2 during the development and resolution of an experimental arthritis	6
Signal Inhibitory Receptor on Leukocytes-1 is highly expressed on lung monocytes, but absent on mononuclear phagocytes in skin and colon	5
Eosinophils increase macrophage ability to control intracellular Leishmania amazonensis infection via PGD2 paracrine activity in vitro	5
Differential roles of regulatory T cells in Alzheimer's disease	5

An outlook on antigen-specific adoptive immunotherapy for viral infections with a focus on COVID-19	5
Expression and function of SLAMF6 in CD8+ T lymphocytes of patients with severe aplastic anemia	5
Deep sequencing reveals the skewed B-cell receptor repertoire in plaques and the association between pathogens and atherosclerosis	5
Human decidual gamma/delta T cells possess unique effector and TCR repertoire profiles during pregnancy	5
Suppression of anti-drug antibody formation against coagulation factor VIII by oral delivery of anti-CD3 monoclonal antibody in hemophilia A mice	5
Paeonol attenuates Substance P-induced urticaria by inhibiting Src kinase phosphorylation in mast cells	5
TREX1 plays multiple roles in human diseases	5
Immunomodulatory action of synbiotic comprising of newly isolated lactic acid producing bacterial strains against allergic asthma in mice	5
Living on the border of the CNS: Dural immune cells in health and disease	5
Impaired plasma cell differentiation associates with increased oxidative metabolism in IκBNS-deficient B cells	5
Oral tolerance to prevent anti-drug antibody formation in protein replacement therapies	5
Piperine suppresses inflammatory fibroblast-like synoviocytes derived from rheumatoid arthritis patients Via NF-κB inhibition	5
Comments on the ambiguity of selected surface markers, signaling pathways and omics profiles hampering the identification of myeloid-derived suppressor cells	5
A clinical focus on oral tolerance in the development, prevention, and management of food allergy	4
Polymorphisms in TNFAIP3, but not in STAT4, BANK1, BLK, and TNFSF4, are associated with susceptibility to Takayasu arteritis	4
C6orf120 gene knockout in rats mitigates concanavalin A‑induced autoimmune hepatitis via regulating NKT cells	4
Full-length IL-33 augments pulmonary fibrosis in an ST2- and Th2-independent, non-transcriptomic fashion	4
Interactions of mesenchymal stromal/stem cells and immune cells following MSC-based therapeutic approaches in rheumatoid arthritis	4
BMDCs induce the generation of the CD103+CD8+ tissue-resident memory T cell subtype, which amplifies local tumor control in the genital tract	4
AMPK activator AICAR in combination with anti-mouse IL10 mAb restores the functionality of intra-tumoral Tfh cells in the 4T1 mouse model	4
Soluble CD25 imposes a low-zone IL-2 signaling environment that favors competitive outgrowth of antigen-experienced CD25high regulatory and memory T cells	4
The aberrant expression of CD69 on peripheral T-helper cells in diet-induced inflammation is ameliorated by low-dose aspirin and metformin treatment	4
The CD36 and SR-A/CD204 scavenger receptors fine-tune Staphylococcus aureus-stimulated cytokine production in mouse macrophages	4
Activated neutrophils inhibit chemotactic migration of activated T lymphocytes to CXCL11 by multiple mechanisms	4
Mast cell phenotypic plasticity and their activity under the influence of cathelicidin-related antimicrobial peptide (CRAMP) and IL-33 alarmins	4
Inhibition of hexokinase 2 with 3-BrPA promotes MDSCs differentiation and immunosuppressive function	4
Expression of SARS-CoV-2 receptor angiotensin-converting enzyme 2 by activating protein-1 in human mast cells	4
Vaccination against SARS-CoV-2 using extracellular blebs derived from spike protein-expressing dendritic cells	4
Fluvastatin enhances IL-33-mediated mast cell IL-6 and TNF production	4
Stat5B is required for IgE-Mediated mast cell function in vitro and in vivo	4
Methyl butyrate attenuates concanavalin A-induced autoimmune hepatitis by inhibiting Th1-cell activation and homing to the liver	4
Brief report: Enhanced DRα1-mMOG-35-55 treatment of severe EAE in MIF-1-deficient male mice	4
Thebaine induces anaphylactic reactions via the MRGPRX2 receptor pathway on mast cells	4
Caspase-11 regulates lung inflammation in response to house dust mites	4
The frequency and dynamics of CD4+ mucosal‐associated invariant T (MAIT) cells in active pulmonary tuberculosis	4
The effects of age, origin, and biological sex on rodent mast cell (BMMC and MC/9) and basophil (RBL-2H3) phenotype and function	4
NFAT5 contributes to the pathogenesis of experimental autoimmune encephalomyelitis (EAE) and decrease of T regulatory cells in female mice	4
Zoledronic acid mediated differential activation of NK cells in different organs of WT and Rag2 mice; stark differences between the bone marrow and gingivae	4
Protective immune response mediated by neutrophils in experimental visceral leishmaniasis is enhanced by IL-32γ	4
A specific Leishmania infantum polyepitope vaccine triggers Th1-type immune response and protects against experimental visceral leishmaniasis	4
ATF6 promotes liver fibrogenesis by regulating macrophage-derived interleukin-1α expression	4
Hsp65-producing Lactococcus lactis inhibits experimental autoimmune encephalomyelitis by preventing cell migration into spinal cord	3
Phosphatidylserine-mediated oral tolerance	3
Attenuated airways inflammation and remodeling in IL-37a and IL-37b transgenic mice with an ovalbumin-induced chronic asthma	3
TRPV4 is not the molecular sensor for bacterial lipopolysaccharides-induced calcium signaling	3
Pharmacological MEK inhibition promotes polyclonal T-cell reconstitution and suppresses xenogeneic GVHD	3
PHF14 is required for germinal center B cell development	3
Changes in the natural killer cell repertoire and function induced by the cancer immune adjuvant candidate IMMUNEPOTENT-CRP	3
Mocravimod, a S1P receptor modulator, increases T cell counts in bone marrow biopsies from patients undergoing allogeneic hematopoietic stem cell transplantation	3
Cellular and humoral responses to SARS-CoV-2 vaccination in immunosuppressed patients	3
Dipeptidylcarboxypeptidase of Leishmania donovani: A potential vaccine molecule against experimental visceral leishmaniasis	3
Phloretin suppresses intestinal inflammation and maintained epithelial tight junction integrity by modulating cytokines secretion in in vitro model of gut inflammation	3
B16 melanomas evade antitumor immunity by the loss of epitope presentation and the acquisition of tumor resistance to granzyme B	3
Downregulation of a tumor suppressor gene LKB1 in lung transplantation as a biomarker for chronic murine lung allograft rejection	3
BLK and BANK1 variants and interactions are associated with susceptibility for primary Sjögren’s syndrome and with some clinical features	3
The interferon regulatory factors, a double-edged sword, in the pathogenesis of type 1 diabetes	3
Substrate-specific presentation of MHC class I-restricted antigens via autophagy pathway	3
Immunogenic properties of immunoglobulin superfamily members within complex biological networks	3
Interferon-gamma increases monocyte PD-L1 but does not diminish T-cell activation	3
Restoring tolerance to β-cells in Type 1 diabetes: Current and emerging strategies	3
Human dental pulp cells modulate CD8+ T cell proliferation and efficiently degrade extracellular ATP to adenosine in vitro	3
Exposure of ovalbumin during pregnancy prevents the development of allergic rhinitis in offspring through the induction of mast cell autophagy	3
T-cell evasion and invasion during HIV-1 infection: The role of HIV-1 Tat protein	3
Immunoglobulin A promotes IL-6 and IL-8 production, proliferation, and migration by the human bronchial smooth muscle cells	3
Chronic IFNα treatment induces leukopoiesis, increased plasma succinate and immune cell metabolic rewiring	3
Trichinella spiralis cystatin, TsCstN, modulates STAT4/IL-12 to specifically suppress IFN-γ production	3
“Near Cure” treatment of severe acute EAE in MIF-1-deficient female and male mice with a bifunctional MHCII-derived molecular construct	3
Dampening of cytotoxic innate lymphoid cells: A new tumour immune escape mechanism in B cell non-Hodgkin's lymphoma	3
Potential role for oral tolerance in gene therapy	3
Dectin-2 promotes house dust mite-skewed Th2 response through the activation of cDC2s	3
Developmental pathways of myeloid-derived suppressor cells in neoplasia	3
Glucan particles as a novel adjuvant for the induction of experimental autoimmune encephalomyelitis	3
Functional responses of resident human T cells in intact liver tissue	3