Cellular Immunology

Article	Citations
The roles of tumor-associated macrophages in tumor angiogenesis and metastasis	197
IL-6 as a major regulator of MDSC activity and possible target for cancer immunotherapy	136
Intranasal delivery of cationic liposome-protamine complex mRNA vaccine elicits effective anti-tumor immunity	88
The exosomes derived from CAR-T cell efficiently target mesothelin and reduce triple-negative breast cancer growth	79
Regulation of ROS in myeloid-derived suppressor cells through targeting fatty acid transport protein 2 enhanced anti-PD-L1 tumor immunotherapy	64
Galectin-9 as a biomarker of disease severity	57
Regulatory B cells in infection, inflammation, and autoimmunity	50
Building a CAR-Treg: Going from the basic to the luxury model	45
Role of orally induced regulatory T cells in immunotherapy and tolerance	44
Regulatory T cell therapy: Current and future design perspectives	39
Protective immunity after COVID-19 has been questioned: What can we do without SARS-CoV-2-IgG detection?	38
Engineered regulatory T cells expressing myelin-specific chimeric antigen receptors suppress EAE progression	35
Myeloid-derived suppressor cells (MDSC): When good intentions go awry	35
Radiotherapy and cGAS/STING signaling: Impact on MDSCs in the tumor microenvironment	34
MDSCs, ageing and inflammageing	30
Regulatory T cells: Master thieves of the immune system	30
Sex differences in EAE reveal common and distinct cellular and molecular components	29
MDSCs in liver cancer: A critical tumor-promoting player and a potential therapeutic target	28
STING agonist and IDO inhibitor combination therapy inhibits tumor progression in murine models of colorectal cancer	27
Combined antitumor effects of anti-EGFR variant III CAR-T cell therapy and PD-1 checkpoint blockade on glioblastoma in mouse model	27
Effects of vitamin D on macrophages and myeloid-derived suppressor cells (MDSCs) hyperinflammatory response in the lungs of COVID-19 patients	26
Functional responsiveness of memory T cells from COVID-19 patients	26
CD4+ T cell phenotypes in the pathogenesis of immune thrombocytopenia	26
Human and murine memory γδ T cells: Evidence for acquired immune memory in bacterial and viral infections and autoimmunity	25
MS4A1 expression and function in T cells in the colorectal cancer tumor microenvironment	23

Piper Nigrum extract improves OVA-induced nasal epithelial barrier dysfunction via activating Nrf2/HO-1 signaling	23
New disease old vaccine: Is recombinant BCG vaccine an answer for COVID-19?	22
Resveratrol attenuates TNBC lung metastasis by down-regulating PD-1 expression on pulmonary T cells and converting macrophages to M1 phenotype in a murine tumor model	21
CD8+ T cells: The past and future of immune regulation	20
Regulating the regulators: Is introduction of an antigen-specific approach in regulatory T cells the next step to treat autoimmunity?	20
Sex differences in M2 polarization, chemokine and IL-4 receptors in monocytes and macrophages from asthmatics	20
The neoepitopes on methylglyoxal (MG) glycated LDL create autoimmune response; autoimmunity detection in T2DM patients with varying disease duration	19
Neutrophil recruitment mediated by sphingosine 1-phosphate (S1P)/S1P receptors during chronic liver injury	19
SARS-CoV-2 peptides bind to NKG2D and increase NK cell activity	18
CD4+ T cells engineered with FVIII-CAR and murine Foxp3 suppress anti-factor VIII immune responses in hemophilia a mice	18
Towards antigen-specific Tregs for type 1 diabetes: Construction and functional assessment of pancreatic endocrine marker, HPi2-based chimeric antigen receptor	18
HMGB1-induced ILC2s activate dendritic cells by producing IL-9 in asthmatic mouse model	18
Molecular cargo in myeloid-derived suppressor cells and their exosomes	17
B7-H3: A promising therapeutic target for autoimmune diseases	16
Curdlan stimulates tissue mast cells to synthesize pro-inflammatory mediators, generate ROS, and migrate via Dectin-1 receptor	16
Roles of the tissue-type plasminogen activator in immune response	16
CD36 regulates LPS-induced acute lung injury by promoting macrophages M1 polarization	16
Cytokine stimulation of the choriocarcinoma cell line JEG-3 leads to alterations in the HLA-G expression profile	15
Distinct roles of ICOS and CD40L in human T-B cell adhesion and antibody production	15
SIRT1 induces the accumulation of TAMs at colorectal cancer tumor sites via the CXCR4/CXCL12 axis	15
Interleukin 27 as an inducer of antiviral response against chikungunya virus infection in human macrophages	15
IL-1β enhances human placenta-derived mesenchymal stromal cells ability to mediate Th1/Th2 and Th1/CD4+IL-10+ T cell balance and regulates its adhesion, proliferation and migration via PD-L1	15
Distinct anti-inflammatory properties of alpha1-antitrypsin and corticosteroids reveal unique underlying mechanisms of action	15
Schwann cells promote lung cancer proliferation by promoting the M2 polarization of macrophages	15
The effects of delta-9-tetrahydrocannabinol (THC) on inflammation: A review	14
Inclusion of Dap10 or 4-1BB costimulation domains in the chPD1 receptor enhances anti-tumor efficacy of T cells in murine models of lymphoma and melanoma	14
Blockade of TLRs-triggered macrophage activation by caffeic acid exerted protective effects on experimental ulcerative colitis	14
The receptor for advanced glycation endproducts (RAGE) decreases survival of tumor-bearing mice by enhancing the generation of lung metastasis-associated myeloid-derived suppressor cells	14
Epigallocatechin-3 gallate regulates macrophage subtypes and immunometabolism to ameliorate experimental autoimmune encephalomyelitis	14
Myeloid-derived suppressor cells as cellular immunotherapy in transplantation and autoimmune diseases	14
Rapamycin facilitates differentiation of regulatory T cells via enhancement of oxidative phosphorylation	14
The role of the BTLA-HVEM complex in the pathogenesis of autoimmune diseases	14
Identification, selection, and expansion of non-gene modified alloantigen-reactive Tregs for clinical therapeutic use	14
Regulation and dysregulation of CARD14 signalling and its physiological consequences in inflammatory skin disease	14
Long non-coding RNA GAS5 regulates Th17/Treg imbalance in childhood pneumonia by targeting miR-217/STAT5	13
Human splenic myeloid derived suppressor cells: Phenotypic and clustering analysis	13
Lipid metabolism in asthma: Immune regulation and potential therapeutic target	13
MiR-1294 suppresses ROS-dependent inflammatory response in atopic dermatitis via restraining STAT3/NF-κB pathway	13
C C chemokine receptor 5 antagonist alleviates inflammation by regulating IFN-γ/IL-10 and STAT4/Smad3 signaling in a mouse model of autoimmune encephalomyelitis	13
The hepatic microenvironment and regulatory T cells	13
Stem cell-like memory T cells: A perspective from the dark side	13
The lncRNA PVT1 regulates autophagy in regulatory T cells to suppress heart transplant rejection in mice by targeting miR-146a	13
Type 1 helper T cells generate CXCL9/10-producing T-bet+ effector B cells potentially involved in the pathogenesis of rheumatoid arthritis	13
Early recruited neutrophils promote asthmatic inflammation exacerbation by release of neutrophil elastase	13
Roxithromycin inhibits compound 48/80-induced pseudo-allergy via the MrgprX2 pathway both in vitro and in vivo	12
Regulation of humoral immune response by HIF-1α-dependent metabolic reprogramming of the germinal center reaction	12
Importance of myeloid derived suppressor cells in cancer from a biomarker perspective	12
Overexpression of DAPK1-mediated inhibition of IKKβ/CSN5/PD-L1 axis enhances natural killer cell killing ability and inhibits tumor immune evasion in gastric cancer	12
Understanding natural killer cell biology from a single cell perspective	12
Activated mesangial cells acquire the function of antigen presentation	12

Recombinant Rv3261 protein of Mycobacterium tuberculosis induces apoptosis through a mitochondrion-dependent pathway in macrophages and inhibits intracellular bacterial growth	12
Down-regulation of LncRNA 2900052N01Rik inhibits LPS-induced B cell function in vitro	12
Gene polymorphisms of LGALS2, LGALS3 and LGALS9 in patients with rheumatoid arthritis	12
Targeting of myeloid-derived suppressor cells by all-trans retinoic acid as host-directed therapy for human tuberculosis	11
G-CSF promotes alloregulatory function of MDSCs through a c-Kit dependent mechanism	11
Cellular uptake and anti-inflammatory effects of palm oil-derived delta (δ)-tocotrienol in microglia	11
Tissue-resident macrophage inflammaging aggravates homeostasis dysregulation in age-related diseases	11
Application of mesenchymal stem cell-derived exosomes in kidney diseases	11
Effects of omalizumab on basophils: Potential biomarkers in asthma and chronic spontaneous urticaria	11
Exploration of the effect of mixed probiotics on microbiota of allergic asthma mice	11
Lck signaling inhibition causes improvement in clinical features of psoriatic inflammation through reduction in inflammatory cytokines in CD4+ T cells in imiquimod mouse model	11
Genomic, proteomic, and systems biology approaches in biomarker discovery for multiple sclerosis	11
Modulation of PD-1/PD-L1 axis in myeloid-derived suppressor cells by anti-cancer treatments	11
Consequences and mechanisms of myelin debris uptake and processing by cells in the central nervous system	11
The role of miRNA-155 in the immunopathogenesis of obliterative airway disease in mice induced by circulating exosomes from human lung transplant recipients with chronic lung allograft dysfunction	11
Skin well-being in diabetes: Role of macrophages	11
Lactic acid suppresses MRGPRX2 mediated mast cell responses	11
NK cells modulate T cell responses via interaction with dendritic cells in Chlamydophila pneumoniae infection	11
Tumor-related stress regulates functional plasticity of MDSCs	10
Overexpression of early T cell differentiation-specific transcription factors transforms the terminally differentiated effector T cells into less differentiated state	10
Comparing thermal stress reduction strategies that influence MDSC accumulation in tumor bearing mice	10
A transgene-encoded truncated human epidermal growth factor receptor for depletion of anti- B-cell maturation antigen CAR-T cells	10
Extracellular vesicles released by myeloid-derived suppressor cells from pregnant women modulate adaptive immune responses	10
The role of PAK4 in the immune system and its potential implication in cancer immunotherapy	10
Imaging the neutrophil: Intravital microscopy provides a dynamic view of neutrophil functions in host immunity	10
Development, phenotypes of immune cells in BTBR TItpr3/J mice	10
Age-associated B cells indicate disease activity in rheumatoid arthritis	10
Differential recognition and cytokine induction by the peptidorhamnomannan from Sporothrix brasiliensis and S. Schenckii	9
Promoter anchored interaction landscape of THP-1 macrophages captures early immune response processes	9
CCR5 attenuates neutrophilic airway inflammation exacerbated by infection with rhinovirus	9
Sorted B cell transcriptomes point towards actively regulated B cell responses during ongoing chronic hepatitis B infections	9
The diverse roles of myeloid derived suppressor cells in mucosal immunity	9
MiR-451a enhances the phagocytosis and affects both M1 and M2 polarization in macrophages	9
Microbiota in organ transplantation: An immunological and therapeutic conundrum?	9
Loss of HLA-class-I expression in non-small-cell lung cancer: Association with prognosis and anaerobic metabolism	9
Exosomal miR-27a-3p derived from tumor-associated macrophage suppresses propranolol sensitivity in infantile hemangioma	9
Modulating glutamine metabolism to control viral immuno-inflammatory lesions	9
Potential therapeutic effect of low-dose paclitaxel in melanoma patients resistant to immune checkpoint blockade: A pilot study	8
MicroRNA-26b-5p alleviates murine collagen-induced arthritis by modulating Th17 cell plasticity	8
Mast cells modulate early responses to Mycobacterium bovis Bacillus Calmette-Guerin by phagocytosis and formation of extracellular traps	8
Lipid metabolism and neutrophil function	8
A novel missense mutation in TNFAIP3 causes haploinsufficiency of A20	8
Tolerogenic vaccines: Targeting the antigenic and cytokine niches of FOXP3+ regulatory T cells	8
Causal link between immunoglobulin G glycosylation and cancer: A potential glycobiomarker for early tumor detection	8
HDAC1 potentiates CD4 + T cell activation by inhibiting miR-124 and promoting IRF1 in systemic lupus erythematosus	8
IL-33 priming amplifies ATP-mediated mast cell cytokine production	8
Deciphering the role of calcium homeostasis in T cells functions during mycobacterial infection	8
Combined TLR4 and TLR9 agonists induce distinct phenotypic changes in innate immunity in vitro and in vivo	8
Full-length IL-33 regulates Smad3 phosphorylation and gene transcription in a distinctive AP2-dependent manner	8
Mechanism of taurine reducing inflammation and organ injury in sepsis mice	8
IL-33 induced airways inflammation is partially dependent on IL-9	8
Th1 polarization in the tumor microenvironment upregulates the myeloid-derived suppressor-like function of macrophages	8
The role of sirtuin 1 on the induction of trained immunity	8
DIM mitigates the development of experimental autoimmune encephalomyelitis by maintaining the stability and suppressive function of regulatory T cells	7
Critical protein-protein interactions within the CARMA1-BCL10-MALT1 complex: Take-home points for the cell biologist	7
Exploiting immunometabolism and T cell function for solid organ transplantation	7
IL-7 receptor alpha defines heterogeneity and signature of human effector memory CD8+ T cells in high dimensional analysis	7
HMGB1 aggravates lipopolysaccharide-induced acute lung injury through suppressing the activity and function of Tregs	7
d-mannose administration improves autoimmune hepatitis by upregulating regulatory T cells	7
Evaluation of autophagy mediators in myeloid-derived suppressor cells during human tuberculosis	7
Expression regulation and function of PD-1 and PD-L1 in T lymphoma cells	7
Monocytic myeloid-derived suppressor cells home to tumor-draining lymph nodes via CCR2 and locally modulate the immune response	7
CRISPR/Cas9-mediated demethylation of FOXP3-TSDR toward Treg-characteristic programming of Jurkat T cells	7
Artemisinin derivative TPN10466 suppresses immune cell migration and Th1/Th17 differentiation to ameliorate disease severity in experimental autoimmune encephalomyelitis	7
Rubicon promotes the M2 polarization of Kupffer cells via LC3-associated phagocytosis-mediated clearance to improve liver transplantation	7
FGFR1 promotes tumor immune evasion via YAP-mediated PD-L1 expression upregulation in lung squamous cell carcinoma	7
Tumor-infiltrating neutrophils and peripheral neutrophil-to-lymphocyte ratio conversely predicted the prognosis of patients with non-small cell lung cancer	7
Multiple genetic programs contribute to CD4 T cell memory differentiation and longevity by maintaining T cell quiescence	7
Live imaging of the pulmonary immune environment	7
Evaluation of mechanisms of action of re-purposed drugs for treatment of COVID-19	6
In vitro 2D and 3D cancer models to evaluate compounds that modulate macrophage polarization	6
Regulation of an adaptor protein STING by Hsp90β to enhance innate immune responses against microbial infections	6
Infectious tolerance. What are we missing?	6
IFN-γ+ CD4+T cell-driven prophylactic potential of recombinant LDBPK_252400 hypothetical protein of Leishmania donovani against visceral leishmaniasis	6
THP-1 cells increase TNF-α production upon LPS + soluble human IgG co-stimulation supporting evidence for TLR4 and Fcγ receptors crosstalk	6
Role of formyl peptide receptor 2 (FPR2) in modulating immune response and heart inflammation in an experimental model of acute and chronic Chagas disease	6
Gain-of-function mutations in CARD11 promote enhanced aggregation and idiosyncratic signalosome assembly	6
The impact of TLR7 agonist R848 treatment on mast cell phenotype and activity	6
An unmet need: Harmonization of IL-7 and IL-15 combination for the ex vivo generation of minimally differentiated T cells	6
Bcl10 is associated with actin dynamics at the T cell immune synapse	6

The impact of MDSCs on the efficacy of preventive and therapeutic HIV vaccines	6
Neutralization of IL-17 and treatment with IL-2 protects septic arthritis by regulating free radical production and antioxidant enzymes in Th17 and Tregs: An immunomodulatory TLR2 versus TNFR response	6
Deltex-1 is indispensible for the IL-6 and TGF-β treatment-triggered differentiation of Th17 cells	6
Par3 regulates the asymmetric division of basal stem cells in psoriasis via the Par3/mInsc/LGN signaling axis	6
Humoral autoimmunity after solid organ transplantation: Germinal ideas may not be natural	6
The splicing factor SRSF1 stabilizes the mRNA of TSLP to enhance acute lung injury	6
Usefulness of IL-21, IL-7, and IL-15 conditioned media for expansion of antigen-specific CD8+ T cells from healthy donor-PBMCs suitable for immunotherapy	5
Neutrophils in the tumor microenvironment and their functional modulation by mesenchymal stromal cells	5
Generation and functional assessment of nonhuman primate regulatory dendritic cells and their therapeutic efficacy in renal transplantation	5
Mucosal-Associated Invariant T cells exhibit distinct functional signatures associated with protection against typhoid fever	5
An outlook on antigen-specific adoptive immunotherapy for viral infections with a focus on COVID-19	5
Oral tolerance and oral immunotherapy for food allergy: Evidence for common mechanisms?	5
Pulmonary inflammatory response to influenza virus infection in pigs is regulated by DAP12 and macrophage M1 and M2 phenotypes	5
Suppression of anti-drug antibody formation against coagulation factor VIII by oral delivery of anti-CD3 monoclonal antibody in hemophilia A mice	5
Muscone promotes functional recovery by facilitating microglia polarization into M2 phenotype through PPAR-γ pathway after ischemic stroke	5
Human placenta derived mesenchymal stromal cells alleviate GVHD by promoting the generation of GSH and GST in PD-1+T cells	5
Early-life infection of the airways with Streptococcus pneumoniae exacerbates HDM-induced asthma in a murine model	5
Type 1 and 2 diabetes are associated with reduced natural killer cell cytotoxicity	5
A Leishmania amastigote-specific hypothetical protein evaluated as recombinant protein plus Th1 adjuvant or DNA plasmid-based vaccine to protect against visceral leishmaniasis	5
Impaired plasma cell differentiation associates with increased oxidative metabolism in IκBNS-deficient B cells	5
Itaconate indirectly influences expansion of effector T cells following vaccination with Francisella tularensis live vaccine strain	5
Age-related changes in PD-1 expression coincide with increased cytotoxic potential in Vδ2 T cells during infancy	5
Residual immune activation in HIV-Infected individuals expands monocytic-myeloid derived suppressor cells	5
Genetical engineering for NK and T cell immunotherapy with CRISPR/Cas9 technology: Implications and challenges	5
The ERM protein moesin regulates natural killer cell homeostasis in vivo	5
Deep sequencing reveals the skewed B-cell receptor repertoire in plaques and the association between pathogens and atherosclerosis	5
Gram-positive Staphylococcus aureus LTA promotes distinct memory-like effects in murine bone marrow neutrophils	5
CARD19, the protein formerly known as BinCARD, is a mitochondrial protein that does not regulate Bcl10-dependent NF-κB activation after TCR engagement	5
Macrophages in intestinal fibrosis and regression	5
Imaging: Gear up for mechano-immunology	5
Signal Inhibitory Receptor on Leukocytes-1 is highly expressed on lung monocytes, but absent on mononuclear phagocytes in skin and colon	5
Neutrophils, functions beyond host defense	5
Soluble PD-1 (sPD-1) is expressed in human macrophages	5
Expression and function of SLAMF6 in CD8+ T lymphocytes of patients with severe aplastic anemia	5
Neutrophil extracellular traps: Modulation mechanisms by pathogens	5
Targeting immunosuppressor cells with nanoparticles in autoimmunity: How far have we come to?	4
Lnc-17Rik promotes the immunosuppressive function of Myeloid-Derived suppressive cells in esophageal cancer	4
Cytomegalovirus specific polyfunctional T-cell responses expressing CD107a predict control of CMV infection after liver transplantation	4
Recent advances into the role of pattern recognition receptors in transplantation	4
Brief report: Enhanced DRα1-mMOG-35-55 treatment of severe EAE in MIF-1-deficient male mice	4
A clinical focus on oral tolerance in the development, prevention, and management of food allergy	4
Oral tolerance to prevent anti-drug antibody formation in protein replacement therapies	4
C6orf120 gene knockout in rats mitigates concanavalin A‑induced autoimmune hepatitis via regulating NKT cells	4
TNF contributes to T-cell exhaustion in chronic L. mexicana infections of mice through PD-L1 up-regulation	4
NFAT5 contributes to the pathogenesis of experimental autoimmune encephalomyelitis (EAE) and decrease of T regulatory cells in female mice	4
IL-3 Expands Pre-Basophil and Mast Cell Progenitors by Upregulating the IL-3 Receptor Expression	4
Autophagy efficacy and vitamin D status: Population effects	4
Expression of SARS-CoV-2 receptor angiotensin-converting enzyme 2 by activating protein-1 in human mast cells	4
The aberrant expression of CD69 on peripheral T-helper cells in diet-induced inflammation is ameliorated by low-dose aspirin and metformin treatment	4
Manipulating the microbiome to enhance oral tolerance in food allergy	4
IRF8 and BATF3 interaction enhances the cDC1 specific Pfkfb3 gene expression	4
Programmed T cell differentiation: Implications for transplantation	4
Surviving the storm: Dealing with COVID-19	4
TAK1 lessens the activity of the paracaspase MALT1 during T cell receptor signaling	4
Visualizing immune responses of the airway mucosa	4
The LUBAC participates in lysophosphatidic acid-induced NF-κB activation	4
Comments on the ambiguity of selected surface markers, signaling pathways and omics profiles hampering the identification of myeloid-derived suppressor cells	4
BMDCs induce the generation of the CD103+CD8+ tissue-resident memory T cell subtype, which amplifies local tumor control in the genital tract	4
Zoledronic acid mediated differential activation of NK cells in different organs of WT and Rag2 mice; stark differences between the bone marrow and gingivae	4
Stat5B is required for IgE-Mediated mast cell function in vitro and in vivo	4
ATF6 promotes liver fibrogenesis by regulating macrophage-derived interleukin-1α expression	4
Fine particulate matter (PM2.5) induces inhibitory memory alveolar macrophages through the AhR/IL-33 pathway	4
Methyl butyrate attenuates concanavalin A-induced autoimmune hepatitis by inhibiting Th1-cell activation and homing to the liver	4
Trichinella spiralis excretory-secretory antigens selectively inhibit the release of extracellular traps from neutrophils without affecting their additional antimicrobial functions	4
Dose-dependent immunomodulatory effects of metformin on human neonatal monocyte-derived macrophages	4
VISTA as a ligand downregulates LPS-mediated inflammation in macrophages and neutrophils	4
Caspase-11 regulates lung inflammation in response to house dust mites	4
The Fyn-Stat5 cascade is required for Fcγ receptor-mediated mast cell function	4
The CBM complex: A growing multiplicity of cellular functions, regulatory mechanisms and connections to human disease	4
Repeated exposure to inactivated Streptococcus pneumoniae induces asthma-like pathological changes in mice in the presence of IL-33	4
A specific Leishmania infantum polyepitope vaccine triggers Th1-type immune response and protects against experimental visceral leishmaniasis	4
Reactive myelopoiesis and the onset of myeloid-mediated immune suppression: Implications for adoptive cell therapy	4