Canadian Journal of Physiology and Pharmacology

Article	Citations
Gut microbiota dysbiosis in polycystic ovary syndrome: association with obesity — a preliminary report	55
Ribavirin shows antiviral activity against SARS-CoV-2 and downregulates the activity of TMPRSS2 and the expression of ACE2 in vitro	41
After the storm: an objective appraisal of the efficacy of c-kit+ cardiac progenitor cells in preclinical models of heart disease	25
Effect of casein kinase 1α inhibition on autophagy flux and the AKT/phospho-β-catenin (S552) axis in HCT116, a RAS-mutated colorectal cancer cell line	21
Vascular smooth muscle remodeling in health and disease	21
Cpt1a promoted ROS-induced oxidative stress and inflammation in liver injury via the Nrf2/HO-1 and NLRP3 inflammasome signaling pathway	20
Molecular hydrogen downregulates acute exhaustive exercise-induced skeletal muscle damage	17
Metabolically healthy obesity: is there a link with polyunsaturated fatty acid intake and status?	17
Theobromine ameliorates nonalcoholic fatty liver disease by regulating hepatic lipid metabolism via mTOR signaling pathway in vivo and in vitro	17
Effect of high-intensity interval training and high-intensity resistance training on irisin and fibroblast growth factor 21 in men with overweight and obesity	17
The possible protective effect of colchicine against liver damage induced by renal ischemia–reperfusion injury: role of Nrf2 and NLRP3 inflammasome	16
Quercetin modulates NRF2 and NF-κB/TLR-4 pathways to protect against isoniazid- and rifampicin-induced hepatotoxicity in vivo	16
p75NTR silencing inhibits proliferation, migration, and extracellular matrix deposition of hypertrophic scar fibroblasts by activating autophagy through inhibiting the PI3K/Akt/mTOR pathway	16
Silencing of lncRNA PVT1 ameliorates streptozotocin-induced pancreatic β cell injury and enhances insulin secretory capacity by regulating miR-181a-5p	15
Aprocitentan and the endothelin system in resistant hypertension	14
Mechanisms of action of SGLT2 inhibitors and their beneficial effects on the cardiorenal axis	14
Cyanidin-3-O-glucoside attenuates high glucose–induced podocyte dysfunction by inhibiting apoptosis and promoting autophagy via activation of SIRT1/AMPK pathway	14
Inhibition of YAP activation attenuates renal injury and fibrosis in angiotensin II hypertensive mice	14
Rosuvastatin corrects oxidative stress and inflammation induced by LPS to attenuate cardiac injury by inhibiting the NLRP3/TLR4 pathway	13
Alamandine via MrgD receptor attenuates pulmonary fibrosis via NOX4 and autophagy pathway	13
Epigallocatechin-3-gallate inhibits proliferation and triggers apoptosis in colon cancer via the hedgehog/phosphoinositide 3-kinase pathways	13
miR-30a-5p inhibits the proliferation and collagen formation of cardiac fibroblasts in diabetic cardiomyopathy	13
Effect of parthenolide, an NLRP3 inflammasome inhibitor, on insulin resistance in high-fat diet-obese mice	12
High-methionine diet in skeletal muscle remodeling: epigenetic mechanism of homocysteine-mediated growth retardation	12
Metformin attenuates ischemia/reperfusion-induced apoptosis of cardiac cells by downregulation of p53/microRNA-34a via activation of SIRT1	12

A novel regulatory network of linc00174/miR-150-5p/VEGFA modulates pathological angiogenesis in diabetic retinopathy	12
Hyperhomocysteinemia: an instigating factor for periodontal disease	12
Long non-coding RNA SNHG16 regulates E2F1 expression by sponging miR-20a-5p and aggravating proliferative diabetic retinopathy	11
Nicaraven inhibits TNFα-induced endothelial activation and inflammation through suppression of NF-κB signaling pathway	11
Long noncoding RNA GAS5 ameliorates chronic constriction injury induced neuropathic pain in rats by modulation of the miR-452-5p/CELF2 axis	10
Serum prokineticin-2 in prepubertal and adult Klinefelter individuals	10
Vitexin regulates Epac and NLRP3 and ameliorates chronic cerebral hypoperfusion injury	10
Antifibrotic effects of bezafibrate and pioglitazone against thioacetamide-induced liver fibrosis in albino rats	10
Sex-dependent effect of perinatal hypoxia on cardiac tolerance to oxygen deprivation in adults	10
Dual mechanism of modulation of NaV1.8 sodium channels by ouabain	10
The tyrosine kinase inhibitor crizotinib influences blood glucose and mRNA expression of GLUT4 and PPARs in the heart of rats with experimental diabetes	9
Impact of ellagic acid application on doxorubicin-induced cardiovascular toxicity model	9
Facile synthesis of bromelain copper nanoparticles to improve the primordial therapeutic potential of copper against acute myocardial infarction in diabetic rats	9
Comparative protective effects of N-acetylcysteine and melatonin against obesity-induced testicular dysfunction in rats	9
Long non-coding RNA H19 acts as a microRNA-194 sponge to inhibit the apoptosis and promote the proliferation of hypertrophic scar fibroblasts	9
Cardiac hypertrophy caused by hyperthyroidism in rats: the role of ATF-6 and TRPC1 channels	9
Nicorandil prevents the nephrotoxic effect of cyclosporine-A in albino rats through modulation of HIF-1α/VEGF/eNOS signaling	9
Fluoxetine-induced hepatic lipid accumulation is linked to elevated serotonin production	9
Anti-cancer potential of cannabis terpenes in a Taxol-resistant model of breast cancer	9
Trimethylamine N-oxide promotes hyperlipidemia acute pancreatitis via inflammatory response	9
Midazolam suppresses ischemia/reperfusion-induced cardiomyocyte apoptosis by inhibiting the JNK/p38 MAPK signaling pathway	9
α-Amyrin induces GLUT4 translocation mediated by AMPK and PPARδ/γ in C2C12 myoblasts	9
Gut microbiota and the periodontal disease: role of hyperhomocysteinemia	9
Synergistic effect of aminoguanidine andl-carnosine against thioacetamide-induced hepatic encephalopathy in rats: behavioral, biochemical, and ultrastructural evidence	9
Involvement of Rho-kinase/IκB-α/NF-κB activation in IL-1β-induced inflammatory response and oxidative stress in human chondrocytes	8
S-ketamine alleviates carbon tetrachloride-induced hepatic injury and oxidative stress by targeting the Nrf2/HO-1 signaling pathway	8
Anticancer activity of sinapic acid by inducing apoptosis in HT-29 human colon cancer cell line	8
Paeonol inhibits inflammatory response and protects chondrocytes by upregulating sirtuin 1	8
Hepatoprotective effect of linagliptin against liver fibrosis induced by carbon tetrachloride in mice	8
FoxO3 transcription factor promotes autophagy after oxidative stress injury in HT22 cells	8
Hypoxia-driven secretion of extracellular matrix proteins in the exosomes reflects the asymptomatic pathology of rotator cuff tendinopathies	8
Inducible nitric oxide synthase (iNOS) mediates ethanol-induced redox imbalance and upregulation of inflammatory cytokines in the kidney	8
Exercise ameliorates insulin resistance and improves SIRT6-mediated insulin signaling transduction in liver of obese rats	8
The impact of sex and gender on heart–brain axis dysfunction: current concepts and novel perspectives	8
Antioxidant and anti-inflammatory properties of alpha-lipoic acid protect against valproic acid–induced liver injury	7
MiR-145-5p modulates lipid metabolism and M2 macrophage polarization by targeting PAK7 and regulating β-catenin signaling in hyperlipidemia	7
Two-month administration of methylphenidate improves olfactory sensitivity and suppresses appetite in individuals with obesity	7
Inhibition of microRNA-297 alleviates THLE-2 cell injury induced by hypoxia/reoxygenation by inhibiting NLRP3 inflammasome activation via sirtuin 3	7
Participation of the opioid receptor – nitric oxide – cGMP – K+channel pathway in the peripheral antinociceptive effect of nalbuphine and buprenorphine in rats	7
New approaches to the design of analgesic medicinal substances	7
Regulatory role of cardiomyocyte metabolism via AMPK activation in modulating atrial structural, contractile, and electrical properties following atrial fibrillation	7
Upregulation of exonuclease 1 caused by homology-dependent repair confers cisplatin resistance to gastric cancer cells	7
Anisomycin inhibits angiogenesis, growth, and survival of triple-negative breast cancer through mitochondrial dysfunction, AMPK activation, and mTOR inhibition	7
Fibroblast growth factor 21 improves lipopolysaccharide-induced pulmonary microvascular endothelial cell dysfunction and inflammatory response through SIRT1-mediated NF-κB deacetylation	7
Role of the JAK2/STAT3 pathway in angiotensin II-induced enhanced expression of Giα proteins and hyperproliferation of aortic vascular smooth muscle cells	7
Overexpression of mm9_circ_013935 alleviates renal inflammation and fibrosis in diabetic nephropathy via the miR-153-3p/NFIC axis	6
Redox and apoptotic potential of novel ruthenium complexes in rat blood and heart	6
In vivo protective effects of upper zone of growth plate and cartilage matrix associated protein against cartilage degeneration in a monosodium iodoacetate induced osteoarthritis model	6
Melatonin modulates acute cardiac muscle damage induced by carbon tetrachloride — involvement of oxidative damage, glutathione, and arginine and nitric oxide metabolism	6
Therapeutic effect of rupatadine against l-arginine-induced acute pancreatitis in rats: role of inflammation	6

Protective effects of selenium in tacrolimus-induced lung toxicity: potential role of heme oxygenase 1	6
Effects of oleuropein on rat’s atria and thoracic aorta: a study of antihypertensive mechanisms	6
Tetrahydroxystilbene glucoside alleviates angiotensin II induced HUVEC senescence via SIRT1	6
Cardioprotective effects of liraglutide pretreatment on isoprenaline-induced myocardial injury in rats	6
Possible protective effect of TNF-α inhibition and triad NO/cGMP/VEGF activation on gastric ulcer in rats	6
Gender-specific side effects of chemotherapy in pancreatic cancer patients	6
Colchicine attenuates renal ischemia-reperfusion-induced liver damage: implication of TLR4/NF-κB, TGF-β, and BAX and Bcl-2 gene expression	6
Mild hyperhomocysteinemia induces blood–brain barrier dysfunction but not neuroinflammation in the cerebral cortex and hippocampus of wild-type mice	6
COVID-19 and the cardiovascular system: insights into effects and treatments	6
Protecting the aging eye with hydrogen sulfide	6
Role of 7-chloro-4-(phenylselanyl) quinoline in the treatment of oxaliplatin-induced hepatic toxicity in mice	6
The antioxidant and anti-inflammatory activities of caffeine effectively attenuate nonalcoholic steatohepatitis and thioacetamide-induced hepatic injury in male rats	6
Modulation of hydrogen sulfide synthesis improves heart function and endothelium-dependent vasorelaxation in diabetes	6
Cannabinoid 2 receptor agonist and L-arginine combination attenuates diabetic cardiomyopathy in rats via NF-ĸβ inhibition	6
Reorienting of pramipexole as a promising therapy for acute pancreatitis in a rat model by suppressing TLR4\NF-κB p65\NLRP3 inflammasome signaling	6
Taurine alleviates kidney injury in a thioacetamide rat model by mediating Nrf2/HO-1, NQO-1, and MAPK/NF-κB signaling pathways	5
Possible cardioprotective role of NaHS on ECG and oxidative stress markers in an unpredictable chronic mild stress model in rats	5
Systemic study of selected histone deacetylase inhibitors in cardiac complications associated with cancer cachexia	5
Association of blood pressure and BMI to corrected QT interval in young adults	5
Naringin prevents diabetic nephropathy in rats through blockage of oxidative stress and attenuation of the mitochondrial dysfunction	5
Downregulation of acylglycerol kinase suppresses high-glucose-induced endothelial-mesenchymal transition in human retinal microvascular endothelial cells through regulating the LPAR1/TGF-β/Notch signa	5
Exercise training suppresses Mst1 activation and attenuates myocardial dysfunction in mice with type 1 diabetes	5
Vascular and renal telomere shortening in mice exposed to chronic intermittent hypoxia	5
MicroRNA regulation of vascular smooth muscle cells and its significance in cardiovascular diseases	5
Nanoparticle-eluting stents for coronary intervention: formulation, characterization, and in vitro evaluation	5
The protective effect of apelin-13 on cardiorenal toxicity induced by cyclophosphamide	5
The OPG/RANKL/RANK system modulates calcification of common carotid artery in simulated microgravity rats by regulating NF-κB pathway	5
Endothelin A receptors contribute to senescence of brain microvascular endothelial cells	5
7-Chloro-4-(phenylselanyl) quinoline reduces renal oxidative stress induced by oxaliplatin in mice	5
Clinical study of pulmonary CT lesions and associated bronchiectasis in 115 convalescent patients with novel coronavirus pneumonia (COVID-19) in China	5
Galectin-3 mediates high-glucose-induced cardiomyocyte injury by the NADPH oxidase/reactive oxygen species pathway	5
The intervention oftert-butylhydroquinone protects ethanol-induced gastric ulcer in type II diabetic rats: the role of Nrf2 pathway	5
Ghrelin receptor agonist hexarelin attenuates antinociceptive tolerance to morphine in rats	5
4,4′-Dichloro-diphenyl diselenide modulated oxidative stress that differently affected peripheral tissues in streptozotocin-exposed mice	5
Effects of phytocannabinoids on heart rate variability and blood pressure variability in female post-concussion syndrome patients: case series	5
Pterostilbene and its nicotinate derivative ameliorated vascular endothelial senescence and elicited endothelium-dependent relaxations via activation of sirtuin 1	5
L-ergothioneine and metformin alleviates liver injury in experimental type-2 diabetic rats via reduction of oxidative stress, inflammation, and hypertriglyceridemia	5
Knockdown of bone morphogenetic protein type II receptor leads to decreased aquaporin 1 expression and function in human pulmonary microvascular endothelial cells	5
The screening of albumin as a key serum component in preventing release of neutrophil extracellular traps by selectively inhibiting mitochondrial ROS generation	5
Toxicity of silver nanoparticles on endometrial receptivity in female mice	5
Lack of renoprotective effects of targeting the endothelin A receptor and (or) sodium glucose transporter 2 in a mouse model of Type 2 diabetic kidney disease	5
A high dose of estrogen can improve renal ischemia-reperfusion-induced pulmonary injury in ovariectomized female rats	5
Vitamin D3 potentiates the nephroprotective effects of metformin in a rat model of metabolic syndrome: role of AMPK/SIRT1 activation and DPP-4 inhibition	5
Metformin alleviates hydrogen peroxide–induced inflammation and oxidative stress via inhibiting P2X7R signaling in spinal cord tissue cells neurons	5
The role of aldosterone inhibitors in cardiac ischemia–reperfusion injury	4
Unveiling the antibacterial and antioxidant potential of Hedera helix leaf extracts: recent findings	4
Blockade of chloride channel-3 enhances cisplatin sensitivity of cholangiocarcinoma cells though inhibiting autophagy	4
Innate and adaptive immune cells associate with arteriovenous fistula maturation and failure	4
Activation of the Akt/FoxO3 signaling pathway enhances oxidative stress-induced autophagy and alleviates brain damage in a rat model of ischemic stroke	4
Endothelin-1 alters BMP signaling to promote proliferation of pulmonary artery smooth muscle cells	4
Stem cell therapy for cardiac regeneration: past, present, and future	4
Effect of ivabradine in heart failure: a meta-analysis of heart failure patients with reduced versus preserved ejection fraction	4
Neonatal fluoxetine exposure delays reflex ontogeny, somatic development, and food intake similarly in male and female rats	4
Early predictive blood markers of hemorrhagic stroke — influence of cytoflavin therapy	4
CF3-substituted diselenide modulatory effects on oxidative stress, induced by single and repeated morphine administrations, in susceptible tissues of mice	4
Transgenerational impact of topical steroid application on superoxide dismutase activities of hypothalamus-pituitary-adrenal axis in rats	4
Opioid receptor μ, not δ and κ, modulate food intake induced by ghrelin in laying chickens	4
Inhibition of endoplasmic reticulum stress combined with activation of angiotensin-converting enzyme 2: novel approach for the prevention of endothelial dysfunction in type 1 diabetic rats	4
Citral inhibits the nociception in the rat formalin test: effect of metformin and blockers of opioid receptor and the NO-cGMP-K+ channel pathway	4
Intracellular pH regulation and the acid delusion	4
Structure–activity relationship of three new piperazine derivates with anxiolytic-like and antidepressant-like effects	3
Potential role of d-chiro-inositol in reducing oxidative stress in the blood of nonobese women with polycystic ovary syndrome	3
Biased signaling in platelet G-protein coupled receptors	3
The influences of chokeberry extract supplementation on redox status and body composition in handball players during competition phase	3
Involvement of G proteins and Rho kinase in α1-adrenoceptor mediated contractions of the rat portal vein	3
Therapeutic metformin concentrations positively regulate proliferation in endometrial epithelial cells via mTOR activation and augmented mitochondrial strength	3
Effect of nitric oxide–cyclic GMP–K+ channel pathway blockers, naloxone and metformin, on the antinociception induced by the diuretic pamabrom	3
Effect of intracutaneous pyonex on analgesia and sedation in critically ill patients with mechanical ventilation	3
Species-dependent differences in the inhibition of various potassium currents and in their effects on repolarization in cardiac ventricular muscle	3
Circadian regulation of genetic and hormonal risk factors of cardiovascular disease in women	3
Influence of carvedilol and thyroid hormones on inflammatory proteins and cardioprotective factor HIF-1α in the infarcted heart	3
Therapeutic enzymes as non-conventional targets in cardiovascular impairments: A comprehensive review	3
Overexpression of miR-365a-3p relieves sepsis-induced acute myocardial injury by targeting MyD88/NF-κB pathway	3
Role of the NO-cGMP-K+ channels pathway in the peripheral antinociception induced by α-bisabolol	3
Generation of prolactin-inducible protein (Pip) knockout mice by CRISPR/Cas9-mediated gene engineering	3
Ethanol and cyclophosphamide induce similar nephrotoxic effects: possible role for Nox4 and superoxide	3
p-Chloro-diphenyl diselenide modulates Nrf2/Keap1 signaling and counteracts renal oxidative stress in mice exposed to repeated dexamethasone administrations	3
LINC01857 promotes the proliferation, migration, and invasion of gastric cancer cells via regulating miR-4731-5p/HOXC6	3
An animal model of gestational obesity and prediabetes: HISS-dependent insulin resistance induced by a high-sucrose diet in Sprague Dawley rats	3
Cardiopulmonary values and organ blood flows before and during heat stress: data in nine subjects at rest in the upright position	3

The role of visfatin and resistin in an in vitro model of obesity-induced invasive liver cancer	3
The S1PR1 agonist SEW2871 promotes the survival of skin flap	3
Porphyromonas gingivalis infection upregulates the endothelin (ET) system in brain microvascular endothelial cells	3
Adaptive and maladaptive roles of different angiotensin receptors in the development of cardiac hypertrophy and heart failure	3
The protein tyrosine kinase inhibitor genistein suppresses hypoxia-induced atrial natriuretic peptide secretion mediated by the PI3K/Akt-HIF-1α pathway in isolated beating rat atria	3
Novel mediators regulating angiogenesis in diabetic foot ulcer healing	3
Differential regulation of TGFβ type-I receptor expressions in TGFβ1-induced myofibroblast differentiation	3
New insight on the role of liraglutide in alleviating dexamethasone-induced pancreatic cytotoxicity via improving redox status, autophagy flux, and PI3K/Akt/Nrf2 signaling	3
Lipopolysaccharide induces BV2 microglial cell migration via a decrease in SET8 expression	3
Irisin relaxes rat thoracic aorta: MEK1/2 signaling pathway, KV channels, SKCa channels, and BKCa channels are involved in irisin-induced vasodilation	3
The protective effect of muscimol against systemic inflammatory response in endotoxemic mice is independent of GABAergic and cholinergic receptors	3
Effects of physical exercise on baroreflex sensitivity and renal sympathetic nerve activity in chronic nicotine-treated rats	3
The effect of dapagliflozin on myocardial ischemia–reperfusion injury in diabetic rats	3
Effect of high-fat diet on mechanosensitive transient receptor potential channel activation in vagal afferent neurons	3
Nicotinamide adenine dinucleotide attenuates acetaminophen-induced acute liver injury via activation of PARP1, Sirt1, and Nrf2 in mice	3
Inhibitory effect of resveratrol on the pharmacokinetics of ticagrelor in vivo and in vitro	3
Crosstalk among apoptosis, inflammation, and autophagy in relation to melatonin protective effect against contrast-induced nephropathy in rats	3
miR-193a as a potential mediator of WT-1/synaptopodin in the renoprotective effect of Losartan on diabetic kidney	3
The circadian clock protein PER1 is important in maintaining endothelin axis regulation in Dahl salt-sensitive rats	3
TLR/mTOR inflammatory signaling pathway: novel insight for the treatment of schizophrenia	3
Future scope and challenges for congestive heart failure: moving toward development of pharmacotherapy	3
Anti-hyperglycaemic effects of dioxidovanadium complexcis-[VO2(obz)py] avert kidney dysfunction in streptozotocin-induced diabetic male Sprague–Dawley rats	3
Inhibition of angiotensin II–induced hypertrophy and cardiac dysfunction by North American ginseng (Panax quinquefolius)	3
Doxorubicin-induced apoptosis enhances monocyte infiltration and adverse cardiac remodeling in diabetic animals	3
Vasorelaxant effect of monoterpene carvacrol on isolated human umbilical artery	3
Leptin induces a contracting effect on guinea pig tracheal smooth muscle via the Ob-R receptor mechanism: novel evidence	2
Preventing broken hearts in women with breast cancer: a concise review on chemotherapy-mediated cardiotoxicity	2
Ethanol consumption increases renal dysfunction and mortality in a mice model of sub-lethal sepsis	2
Alleviation of adipose–hepatic glycolipid dysregulation by acetate in experimental PCOS model is associated with NF-κB/NLRP3 repression	2
Upregulation of circFOXP1 attenuates inflammation and apoptosis induced by ox-LDL in human umbilical vein endothelial cells by regulating the miR-185-5p/BCL-2 axis	2
Discussion: Drinking hydrogen water enhances endurance and relieves psychometric fatigue: a randomized, double-blind, placebo-controlled study	2
Endothelin system expression in the kidney following cisplatin-induced acute kidney injury in male and female mice	2
Clinical efficacy and safety of two concentrations of intravenous nicardipine hydrochloride for nicardipine-related phlebitis in patients with preeclampsia	2
Telomere shortening velocity of patients administered with hypnotics is accelerated in a gender-differential manner	2
Prolongation of experimental diabetes mellitus increased susceptibility to reperfusion ventricular tachyarrhythmias	2
Involvement of the transient receptor potential A1 in morphine-induced conditioned place preference and physical dependence in mice	2
Sirtuin 3 overexpression preserves maximal sarco(endo)plasmic reticulum calcium ATPase activity in the skeletal muscle of mice subjected to high fat – high sucrose feeding	2
Paradoxical effects of acidosis on the noradrenaline-induced and neurogenic constriction of the rat tail artery at low temperatures	2
Role of cyclic AMP response element binding protein (CREB) in angiotensin II-induced responses in vascular smooth muscle cells	2
Smoothelin-like 1 knockout mice display sex-dependent alterations in blood flow and cardiac function	2
mTOR inhibition as a possible pharmacological target in the management of systemic inflammatory response and associated neuroinflammation by lipopolysaccharide challenge in rats	2
The myokine decorin improves the cardiac function in a rat model of isoprenaline-induced myocardial infarction	2
PPARα/γ, adiponectin, and GLUT4 overexpression induced by moronic acid methyl ester influenced glucose and triglyceride levels of experimental diabetic mice	2
Paraoxonase and oxidative stress changes in left and right ventricles of exhaustively exercised rats	2
Simultaneous intervention against oxidative stress and inflammation by targeting Nrf2/ARE and NLRP3 inflammasome pathway mitigates thioacetamide-induced liver fibrosis in rat	2
Role of mitochondria in the differential action of sodium deoxycholate and ursodeoxycholic acid on rat duodenum	2
Krešimir Krnjević (1927–2021) and GABAergic inhibition: a lifetime dedication	2
Molecular hydrogen: prospective treatment strategy of kidney damage after cardiac surgery	2
Neonatal pain modulates in adolescent rats the antinociceptive effects of fluoxetine and buspirone administrated to their depressive dams during gestation	2
Role of phospholipase C in catecholamine-induced increase in myocardial protein synthesis	2
Modulatory effect of simvastatin on redox status, caspase-3 expression, p-protein kinase B (p-Akt), and brain-derived neurotrophic factor (BDNF) in an ethanol-induced neurodegeneration model	2
The impacts of vorinostat on NADPH oxidase and mitochondrial biogenesis gene expression in the heart of mice model of depression	2
Endurance training-induced cardiac remodeling in a guinea pig athlete's heart model	2
Anti-inflammatory, antinociceptive, and vasorelaxant effects of a new pyrazole compound 5-(1-(2-fluorophenyl)-1H-pyrazol-4-yl)-1H-tetrazole: role of NO/cGMP pathway and calcium channels	2
Knockdown of lysyl oxidase like 1 inhibits the proliferation and pro-fibrotic effects of transforming growth factor-β1-induced hypertrophic scar fibroblasts	2
SNHG8 promotes cell proliferation, migration, and invasion of nasopharyngeal carcinoma cells as an oncogene through miR-588/HMGA2 axis	2
Porphyromonas gingivalis induces cardiovascular dysfunction	2
The effect of selected drugs on the mitigation of myocardial injury caused by gamma radiation	2
High salt-induced morphological and glycocalyx remodeling of human vascular smooth muscle cells is reversible but induces a high sodium salt-like sensitive memory	2
Endothelin antagonism reduces hemoglobin A1c in patients with pulmonary hypertension	2
Mechanism and effects of artesunate on the liver function of rats with type 1 diabetic periodontitis	2
Sex-specific effects of frailty on cardiac structure and function: insights from preclinical models	2
SET8 participates in lipopolysaccharide-mediated BV2 cell inflammation via modulation of TICAM-2 expression	2
Oxygen sensor of the heart	2
Melatonin decreases circulating Trypanosoma cruzi load with no effect on tissue parasite replication	2
COVID-19 pathophysiology and pharmacology: what do we know and how did Canadians respond? A review of Health Canada authorized clinical vaccine and drug trials	2
Inhibition of dipeptidyl peptidase-4 averts free fatty acids deposition in the hearts of oral estrogen–progestin contraceptive-induced hyperinsulinemic female rats	2
Ascorbic acid reduces insulin resistance and pancreatic steatosis by regulating adipocyte hypertrophy in obese ovariectomized mice	2
TMEM98, a novel secretory protein, promotes endothelial cell adhesion as well as vascular smooth muscle cell proliferation and migration	2
Changes in c-fos and p-CREB signaling following exposure to forced swim stress or exogenous corticosterone during morphine-induced place preference are dependent on glucocorticoid receptor in the baso	2
Thyroid hormones regulate reelin expression in neuropsychiatric disorders	2
The non-nutritive sweetener sucralose increases β-arrestin signaling at the constitutively active orphan G protein-coupled receptor GPR52	2
Phosphodiesterase 4D7 selectively regulates cAMP-mediated control of human arterial endothelial cell transcriptomic responses to fluid shear stress	2
β-elemene relieves neuropathic pain in mice through the regulation on C-X-C motif chemokine receptor 3 and GABAA receptor	2
Endothelin A receptor antagonist attenuated renal iron accumulation in iron overload heme oxygenase-1 knockout mice	2
Inhibition of glutamatergic transmission and neuronal excitability by oxycodone in the rat hippocampal CA3 neurons	2
Protective effects of BiP inducer X (BIX) against diabetic cardiomyopathy in rats	2
Short-term effects induced by nicotinamide in ovariectomized females	2
Female-biased association of NOS2-c.1823C>T (rs2297518) with co-susceptibility to metabolic syndrome and asthma	2
Modification of ischemia/reperfusion induced infarct size by ischemic preconditioning in hypertrophied hearts	2
Exchange proteins directly activated by cAMP mediate cardiac repolarization and arrhythmogenesis during chronic heart failure	2
Erythropoietin alters the pharmacokinetics of organic anions mainly eliminated by the kidney in rats	2