OOIR: Observatory of International Research

Papers

(The TQCC of Laboratory Medicine is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Machine Learning Prediction of SARS-CoV-2 Polymerase Chain Reaction Results with Routine Blood Tests	31
A High-Level Overview of the Regulations Surrounding a Clinical Laboratory and Upcoming Regulatory Challenges for Laboratory Developed Tests	31
Absolute Lymphocytes, Ferritin, C-Reactive Protein, and Lactate Dehydrogenase Predict Early Invasive Ventilation in Patients With COVID-19	27
MiR-150 Expression in Chronic Myeloid Leukemia: Relation to Imatinib Response	22
Potential Use of Antigen-Based Rapid Test for SARS-CoV-2 in Respiratory Specimens in Low-Resource Settings in Egypt for Symptomatic Patients and High-Risk Contacts	21
Review of the Clinical Presentation, Pathology, Diagnosis, and Treatment of Leishmaniasis	19
Clinical Utility of Midregional Proadrenomedullin in Patients with COVID-19	17
Utility of Antigen-Based Rapid Diagnostic Test for Detection of SARS-CoV-2 Virus in Routine Hospital Settings	15
The Network That Never Sleeps	14
Trimethylamine N-Oxide is Associated with Heart Failure Risk in Patients with Preserved Ejection Fraction	14
Association of CEA, NSE, CYFRA 21-1, SCC-Ag, and ProGRP with Clinicopathological Characteristics and Chemotherapeutic Outcomes of Lung Cancer	12
MicroRNA-138 Regulates T-Cell Function by Targeting PD-1 in Patients with Hepatitis B Virus–Related Liver Diseases	12
Estimation of Low-Density Lipoprotein Cholesterol Concentration Using Machine Learning	12
Variation in LOD Across SARS-CoV-2 Assay Systems: Need for Standardization	12
Serum IL-6 and TNF-α Levels Are Correlated with Disease Severity in Patients with Ankylosing Spondylitis	11
CRISPR-Based Approaches for Efficient and Accurate Detection of SARS-CoV-2	11
Performance Evaluation of the Siemens SARS-CoV-2 Total Antibody and IgG Antibody Test	10
Evaluation of Serum GDF15, AFP, and PIVKA-II as Diagnostic Markers for HBV-Associated Hepatocellular Carcinoma	10
Initial Clinical Laboratory Response to COVID-19: A Survey of Medical Laboratory Professionals	10
Light Chain Predominant Intact Immunoglobulin Monoclonal Gammopathy Disorders: Shorter Survival in Light Chain Predominant Multiple Myelomas	9
Urinary Exosomes: A Promising Biomarker for Disease Diagnosis	9
Clinical Value of Pepsinogen in the Screening, Prevention, and Diagnosis of Gastric Cancer	8
First Case of Bloodstream Infection Caused by Ruminococcus gnavus in an 85 Year Old Man in China	8
A Literature Review on How We Can Address Medical Laboratory Scientist Staffing Shortages	8
A Meta-Analysis on the Association of Colibactin-Producing pks+ Escherichia coli with the Development of Colorectal Cancer	8

Acquired Thrombotic Thrombocytopenic Purpura After BNT162b2 COVID-19 Vaccine: Case Report and Literature Review	8
Plasma LncRNA MALAT1 Expressions Are Negatively Associated with Disease Severity of Postmenopausal Osteoporosis	7
Light Chain–Predominant Multiple Myeloma Subgroup: Impaired Renal Function Correlates with Decreased Survival	7
Impact of Pool Testing in Detection of Asymptomatic Patients with COVID-19	7
Quantitative Detection of Anti-SARS-CoV-2 Antibodies Using Indirect ELISA	7
Performance of High Throughput SARS-CoV-2 Antigen Testing Compared to Nucleic Acid Testing	7
Looking into the Laboratory Staffing Issues that Affected Ambulatory Care Clinical Laboratory Operations during the COVID-19 Pandemic	7
A Fluorescence-Based Quantitative Analysis for Total Bilirubin in Blood and Urine	7
Novel Methods for Detecting Human Cholesterol Crystals from Sampled Blood	7
Smudge Cells in Chronic Lymphocytic Leukemia: Pathophysiology, Laboratory Considerations, and Clinical Significance	6
Dysregulation of Long Noncoding RNANEAT1/miR-199a-5/BiP Axis in Patients with Diabetic Neuropathy	6
Adequate Antibody Response to COVID-19 Vaccine in Patients with Monoclonal Gammopathies and Light Chain Amyloidosis	6
Criticality of In-House Preparation of Viral Transport Medium in Times of Shortage During COVID-19 Pandemic	6
LINC00205 Promotes Tumor Malignancy of Lung Adenocarcinoma Through Sponging miR-185-5p	6
Highly Sensitive Serum miRNA Panel for the Diagnosis of Hepatocellular Carcinoma in Egyptian Patients with HCV-Related HCC	6
Modified Proline Metabolism and Prolidase Enzyme in COVID-19	6
Clinical Predictors of SARS-CoV-2 Testing Pressure on Clinical Laboratories: A Multinational Study Analyzing Google Trends and Over 100 Million Diagnostic Tests	5
Comparison between the Sofia SARS Antigen FIA Test and the PCR Test in Detection of SARS-CoV-2 Infection	5
Platelet MicroRNA-484 as a Novel Diagnostic Biomarker for Acute Coronary Syndrome	5
Determination of Glyphosate and AMPA in Blood Can Predict the Severity of Acute Glyphosate Herbicide Poisoning	5
Meteorin-like Protein and Asprosin Levels in Children and Adolescents with Obesity and Their Relationship with Insulin Resistance and Metabolic Syndrome	5
Need for Confirmatory Neutralization Tests for Hepatitis B Surface Antigen Tests in Populations with Intermediate Prevalence	5
Chemerin Levels in Acute Coronary Syndrome: Systematic Review and Meta-Analysis	5
Oncology Patients Who Develop Transfusion-Associated Circulatory Overload: An Observational Study	5
Myeloid Sarcoma Expressing Keratins and Mimicking Carcinoma—Case Report and Literature Review	5
EDTA-Induced Pseudothrombocytopenia up to 9 Months after Initial COVID-19 Infection Associated with Persistent Anti-SARS-CoV-2 IgM/IgG Seropositivity	5
Validation of Two Revised, Simplified Criteria for Assessing Sepsis-Associated Disseminated Intravascular Coagulation in ICU Patients with Sepsis-3: A Retrospective Study	4
Clinical Significance of Anti-Modified Citrullinated Vimentin Antibodies in Palindromic Rheumatism	4
Association of SLC22A1,SLCO1B3 Drug Transporter Polymorphisms and Smoking with Disease Risk and Cytogenetic Response to Imatinib in Patients with Chronic Myeloid Leukemia	4
Anti-S Antibody: A Rare Cause of Fetal Hydrops in a Previously Sensitized Mother	4
Urinary MMP-7: A Predictive, Noninvasive Early Marker for Chronic Kidney Disease Development in Patients with Hypertension	4
Circulating Levels of C1q/TNF-Related Protein 3 (CTRP3) and CTRP9 in Gestational Diabetes and Their Association with Insulin Resistance and Inflammatory Cytokines	4
T Cell Senescence by Extensive Phenotyping: An Emerging Feature of COVID-19 Severity	4
Anti-Saccharomyces cerevisiae Antibodies in Rheumatoid Arthritis	4
Incidence of Hepatotoxicity in Iranian Patients With HIV on Antiretroviral Therapies and Its Correlation with Virologic Response to HIV Treatment	4
Diagnostic Value of Circular RNA hsa_circ_0002874 Expression in Peripheral Blood of Patients with Gastric Cancer	4
Whole-Exome Sequencing Reveals a Novel Mutation of FLNA Gene in an Iranian Family with Nonsyndromic Tetralogy of Fallot	4
MALDI-TOF-MS Analysis in the Discovery and Identification of the Serum Peptide Pattern of Pancreatic Ductal Adenocarcinoma	4
Lean Six Sigma Methodologies to Reduce the Cardiac Troponin Turnaround Time in the Core Laboratory	4
Serum Leukocyte Cell-Derived Chemotaxin 2 (LECT2) Level Is Associated with Osteoporosis	4
The Clinical Significance of Staphylococcus aureus Small Colony Variants	4
Evaluation of RNA Isolation Methods in Human Adipose Tissue	4
Metabolomics: A New Tool to Reveal the Nature of Diabetic Kidney Disease	4
Cell-Derived Microparticles in Blood Products from Blood Donors Deficient in Glucose-6-Phosphate Dehydrogenase	4
A Hemolytic Transfusion Reaction Caused by an Unexpected Leb Antibody	4
Application of the Single-Molecule Real-Time Technology (SMRT) for Identification of HKαα Thalassemia Allele	3
Variations in Nomenclature of Clinical Variants between Annotation Tools	3
Acquired FVII Deficiency and Acute Myeloid Leukemia: A Case Report and Literature Review	3
Lymphocyte Aggregation in Low-Grade B-Cell Lymphoma	3
Strategies for Sustainability of University-Based Medical Laboratory Sciences Programs	3

Evaluation of Serum FGL1 as Diagnostic Markers for HBV-Related Hepatocellular Carcinoma	3
Usage of Plasma Presepsin, C-Reactive Protein, Procalcitonin and Proadrenomedullin to Predict Bacteremia in Febril Neutropenia of Pediatric Hematological Malignancy Patients	3
Serum Ferritin Has Limited Prognostic Value on Mortality Risk in Patients with Decompensated Cirrhosis: A Propensity Score Matching Analysis	3
Evaluation of RT-LAMP Assay for Rapid Detection of SARS-CoV-2	3
Cutoff Value of Qualitative HBsAg for Confirmatory HBsAg Using the Chemiluminescence Microparticle Immunoassay Method	3
Pretreatment of Body Fluid Specimens Using Hyaluronidase and Ultracentrifugation	3
Urine Protein Immunofixation Electrophoresis: Free Light Chain Urine Immunofixation Electrophoresis Is More Sensitive than Conventional Assays for Detecting Monoclonal Light Chains and Could Serve as	3
Mycoplasma hominis Meningitis Diagnosed by Metagenomic Next-Generation Sequencing in a Preterm Newborn: a Case Report and Literature Review	3
Kanamycin Supplement for the Disaggregation of Platelet Clumps in EDTA-Dependent Pseudothrombocytopenia Specimens	3
Daratumumab Interference in Flow Cytometry Producing a False Kappa Light Chain Restriction in Plasma Cells	3
A New Auto-RPA-Fluorescence Detection Platform for SARS-CoV-2	3
The Interpretation of Mirror Pattern Bands During Oligoclonal Immunoglobulin Isoelectric Focusing Electrophoresis: A Retrospective Study	3
Serum aspartate aminotransferase is an adverse prognostic indicator for patients with resectable pancreatic ductal adenocarcinoma	3
Lean Principles to Improve Quality in High-Throughput COVID-19 Testing Using SwabSeq: A Barcoded Sequencing-Based Testing Platform	3
Evaluation of Polarized Light and Fluorescence Microscopy of Congo Red Stain in the Diagnosis of Renal Amyloidosis	3
Elevated Kynurenine Levels in Patients with Primary Sjögren’s Syndrome	3
Blood Donors with Thalassemic Trait, Glucose-6-Phosphate Dehydrogenase Deficiency Trait, and Sickle Cell Trait and Their Blood Products: Current Status and Future Perspective	3
Reliable Detection of T-Cell Clonality by Flow Cytometry in Mature T-Cell Neoplasms Using TRBC1: Implementation as a Reflex Test and Comparison with PCR-Based Clonality Testing	3
HbA1c Below the Reportable Range	3
High C-Reactive Protein-to-Lymphocyte Ratio Is Predictive of Unfavorable Prognosis in HBV-Associated Decompensated Cirrhosis	3
Evaluation of the NG-Test CARBA 5 Kit for Rapid Detection of Carbapenemase Resistant Enterobacteriaceae	3
Diagnostic Value of Metagenomic Next Generation Sequencing for Ureaplasma urealyticum Infection: A Case Report	3
Trimethylamine-N-Oxide and Precursors as Novel Potential Biomarkers for Anxiety Disorder	3
Sialic Acid as a Suitable Marker of Clinical Disease Activity in Patients with Crohn’s Disease	3
Use of Self-Collected Saliva Samples for the Detection of SARS-CoV-2	3
Detection of a Cryptic KMT2A/AFDN Gene Fusion [ins(6;11)(q27;q23q23)] in a Pediatric Patient with Newly Diagnosed Acute Myeloid Leukemia	3
Pancreatic Cancer Insights: Optimization of the Diagnostic Capacity of Tumor Biomarkers	3
Storage Duration and Red Blood Cell–Derived Microparticles in Packed Red Blood Cells Obtained from Donors with Thalassemia	3
Pathology—The Beginnings of Laboratory Medicine	3
Erythrocyte Sedimentation Rate in Patients with Renal Insufficiency and Renal Replacement Therapy	2
Trimester-Specific Reference Intervals of Serum Urea, Creatinine, and Uric Acid Among Healthy Pregnant Women in Zhengzhou, China	2
Oxidative Stress Levels and Dynamic Thiol-Disulfide Balance in Preterm Newborns with Bronchopulmonary Dysplasia	2
A Novel USP25::PDGFRA Gene Fusion in a 78 Year Old Patient with a Myeloid Neoplasm	2
Anti-Golgi Antibody as a Potential Indicator for Rheumatoid Arthritis	2
Development of an LC-MS/MS Method for Measurement of Irinotecan and Its Major Metabolites in Plasma: Technical Considerations	2
N-Terminal Prohormone Brain Natriuretic Peptide as a Prognostic Biomarker for the Risk of Complications in Type 2 Diabetes: A Systematic Review and Meta-Analysis	2
Reassessment of Critical Anti-D Antibody Titer in RhD Alloimmunized Antenatal Women	2
Pathogenic Homozygous Mutations in the DBT Gene (c.1174A>C) Result in Maple Syrup Urine Disease in a rs12021720 Carrier	2
Association of Interleukin-6 Polymorphisms with Schizophrenia and Depression: A Case-Control Study	2
Comparison of RhD Typing Results by Serology and Molecular Methods	2
A Novel Mutation of the Membrane Metallo-Endopeptidase Gene Related to Late-Onset Hereditary Polyneuropathy: Case Report and Review of the Literature	2
A Scoping Review of Medical Laboratory Science and Simulation: Promoting a Path Forward with Best Practices	2
Association of Plasma Fibrinogen Levels on Postoperative Day 1 with 2-Year Survival of Orthotopic Liver Transplantation for HBV-Related HCC	2
Evaluation of methods to eliminate analytical interference in multiple myeloma patients with spurious hyperphosphatemia	2
Multisite Pseudomonas aeruginosa Infections Detected by Metagenomic Next-Generation Sequencing in a Child with Aplastic Anemia: A Case Report	2
Topical Application of Methyl Nicotinate Solution Enhances Peripheral Blood Collection	2
Hemolytic Disease of the Fetus and Newborn Caused by Maternal Autoantibody with Mimicking Anti-E Specificity	2
Comparative Evaluation of the Modified Carbapenem Inactivation Method for Phenotypic Detection of Guiana Extended-Spectrum β-Lactamase-Type Carbapenemases in Enterobacterales	2
Protocols to Dissolve Amorphous Urate Crystals in Urine	2
Whole-Exome Sequencing Identifies a Recurrent Small In-Frame Deletion in MYO15A Causing Autosomal Recessive Nonsyndromic Hearing Loss in 3 Iranian Pedigrees	2
Association of rs5742612 Polymorphism in the Promoter Region of IGF1 Gene with Nonalcoholic Fatty Liver Disease: A Case-Control Study	2
The Viability of Hematopoietic Progenitor Cell Grafts after Cryopreservation Does Not Predict Delayed Engraftment in Allogeneic Hematopoietic Stem Cell Transplantation	2
Application of the Fluorescence Method on Sysmex XN9000 Hematology Analyzer for Correcting Platelet Count in Individuals with Microcytosis	2
An Assessment of Gender Equity and Parity Among “Nontraditional” Pathology Awards	2
Validation of a Spectrophotometric Method for Urinary Iodine Determination on Microplate Based on Sandell-Kolthoff Reaction	2
Compound Heterozygous VPS13A Variants in a Patient with Neuroacanthocytosis: A Case Report and Review of the Literature	2
Macroprolactinoma-Induced Syndrome of Inappropriate Antidiuresis and Its Reversal with Dopamine Agonist Therapy	2
D-Dimer Combined With CRP Can Improve the Differential Value of Bacterial Meningitis and Tuberculous Meningitis	2
A meta-analysis of urinary transferrin for early diagnosis of diabetic nephropathy	2
Consistency Between Thyrotropin Receptor Antibody (TRAb) and Thyroid-Stimulating Antibody (TSAb) Levels in Patients with Graves Disease	2
Droplet digital polymerase chain reaction to measure heteroplasmic m.3243A>G mitochondrial mutations	2
Stat Laboratory Interventions to Improve Patient Management in the Emergency Department and Resource Expenditure: A 10-Year Study	2
Loss and Reappearance of A Antigen After Chemotherapy Leading to Blood Group Discrepancy in Acute Myeloid Leukemia: A Case Report	2
Verification and Implementation of HIV Antibody Differentiation Testing to Improve Turnaround Time for the HIV Diagnostic Algorithm	2
Incidental Discovery of a Patient with the Bombay Phenotype	2
SARS-CoV-2 Antibody Testing: Where Are We Now?	2
Methods to Correct Drug-Induced Coagulopathy in Bleeding Emergencies: A Comparative Review	2
Outcome of ABO-Incompatible Kidney Transplantation According to ABO Type of Transfused Plasma: Comparative Analysis Between “Universal” AB and Donor-Type Plasma	2
Accurate Quantification of Monoclonal Immunoglobulins Migrating in the Beta Region on Protein Electrophoresis	2
Evaluation of Intra- and Interlaboratory Variations in SARS-CoV-2 Real-Time RT-PCR Through Nationwide Proficiency Testing	2
The value of metagenomic next-generation sequencing for the diagnosis of pulmonary tuberculosis using bronchoalveolar lavage fluid	2
Prospective Validation of a Machine Learning Model for Low-Density Lipoprotein Cholesterol Estimation	2
Laboratory Strategies to Improve Allergy First-Line Screening in Primary Care	2
Combined Diagnosis of SARS-CoV-2: Rapid Antigen Detection as an Adjunct to Nucleic Acid Detection	2
Serum Ribonucleotide Reductase Subunit M2 in Patients with Chronic Liver Diseases and Hepatocellular Carcinoma	2
Achondroplasia—First Report from India of a Rare FGFR3 Gene Variant	2
Diagnostic Efficiency of Serum-Based Infrared Spectroscopy in Detecting Breast Cancer: A Meta-Analysis	2
Using the BDFX40 Automated Continuous Blood Culture System to Isolate and RecoverStreptobacillus moniliformisin the Presence of 0.05% SPS: A 55-Year, 56-Strain Retrospective Study	2