OOIR: Observatory of International Research

Papers

(The TQCC of Laboratory Medicine is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Types of Assays for SARS-CoV-2 Testing: A Review	53
3D-Printing to Address COVID-19 Testing Supply Shortages	47
Thrombocytopenia Is Associated with COVID-19 Severity and Outcome: An Updated Meta-Analysis of 5637 Patients with Multiple Outcomes	46
Machine Learning Prediction of SARS-CoV-2 Polymerase Chain Reaction Results with Routine Blood Tests	27
Absolute Lymphocytes, Ferritin, C-Reactive Protein, and Lactate Dehydrogenase Predict Early Invasive Ventilation in Patients With COVID-19	27
A High-Level Overview of the Regulations Surrounding a Clinical Laboratory and Upcoming Regulatory Challenges for Laboratory Developed Tests	26
MiR-150 Expression in Chronic Myeloid Leukemia: Relation to Imatinib Response	21
Mesenchymal Stem Cells in COVID-19: A Journey from Bench to Bedside	20
Potential Use of Antigen-Based Rapid Test for SARS-CoV-2 in Respiratory Specimens in Low-Resource Settings in Egypt for Symptomatic Patients and High-Risk Contacts	19
Clinical Utility of Midregional Proadrenomedullin in Patients with COVID-19	17
Clinical Laboratory Employees’ Attitudes Toward Artificial Intelligence	14
Utility of Antigen-Based Rapid Diagnostic Test for Detection of SARS-CoV-2 Virus in Routine Hospital Settings	13
Review of the Clinical Presentation, Pathology, Diagnosis, and Treatment of Leishmaniasis	13
Double-Edged Spike—Are SARS-CoV-2 Serologic Tests Safe Right Now?	13
Verification of 20 Mathematical Formulas for Discriminating Between Iron Deficiency Anemia and Thalassemia Trait in Microcytic Anemia	13
Safety Considerations in the Laboratory Testing of Specimens Suspected or Known to Contain the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)	12
Neurogranin as a Novel Biomarker in Alzheimer’s Disease	12
Incident Command in the Time of COVID-19	11
Variation in LOD Across SARS-CoV-2 Assay Systems: Need for Standardization	11
Comparison of Serum Free and Bioavailable 25-Hydroxyvitamin D Levels in Alzheimer’s Disease and Healthy Control Patients	10
The Network That Never Sleeps	10
MicroRNA-138 Regulates T-Cell Function by Targeting PD-1 in Patients with Hepatitis B Virus–Related Liver Diseases	10
Trimethylamine N-Oxide is Associated with Heart Failure Risk in Patients with Preserved Ejection Fraction	10
CRISPR-Based Approaches for Efficient and Accurate Detection of SARS-CoV-2	10
The Frequency of Discordant Variant Classification in the Human Gene Mutation Database: A Comparison of the American College of Medical Genetics and Genomics Guidelines and ClinVar	9

Quantification by Ultrafiltration and Immunofixation Electrophoresis Testing for Monoclonal Serum Free Light Chains	9
Estimation of Low-Density Lipoprotein Cholesterol Concentration Using Machine Learning	9
Initial Clinical Laboratory Response to COVID-19: A Survey of Medical Laboratory Professionals	8
Serum and Saliva Levels of Cancer Antigen 15-3, Carcinoembryonic Antigen, Estradiol, Vaspin, and Obestatin as Biomarkers for the Diagnosis of Breast Cancer in Postmenopausal Women	8
First Case of Bloodstream Infection Caused by Ruminococcus gnavus in an 85 Year Old Man in China	8
Performance Evaluation of the Siemens SARS-CoV-2 Total Antibody and IgG Antibody Test	8
Light Chain Predominant Intact Immunoglobulin Monoclonal Gammopathy Disorders: Shorter Survival in Light Chain Predominant Multiple Myelomas	8
Soluble CD14 Subtype in Peripheral Blood is a Biomarker for Early Diagnosis of Sepsis	8
Acquired Thrombotic Thrombocytopenic Purpura After BNT162b2 COVID-19 Vaccine: Case Report and Literature Review	8
Impact of Pool Testing in Detection of Asymptomatic Patients with COVID-19	7
A Fluorescence-Based Quantitative Analysis for Total Bilirubin in Blood and Urine	7
Light Chain–Predominant Multiple Myeloma Subgroup: Impaired Renal Function Correlates with Decreased Survival	7
Myeloid Sarcoma Expressing Keratins and Mimicking Carcinoma—Case Report and Literature Review	6
The Association Between Serum Leptin Levels and Cardiovascular Events in Patients with Rheumatoid Arthritis	6
Evaluation of Serum GDF15, AFP, and PIVKA-II as Diagnostic Markers for HBV-Associated Hepatocellular Carcinoma	6
Adequate Antibody Response to COVID-19 Vaccine in Patients with Monoclonal Gammopathies and Light Chain Amyloidosis	6
Quantitative Detection of Anti-SARS-CoV-2 Antibodies Using Indirect ELISA	6
LINC00205 Promotes Tumor Malignancy of Lung Adenocarcinoma Through Sponging miR-185-5p	6
A Meta-Analysis on the Association of Colibactin-Producing pks+ Escherichia coli with the Development of Colorectal Cancer	6
Plasma LncRNA MALAT1 Expressions Are Negatively Associated with Disease Severity of Postmenopausal Osteoporosis	6
Performance of High Throughput SARS-CoV-2 Antigen Testing Compared to Nucleic Acid Testing	6
Criticality of In-House Preparation of Viral Transport Medium in Times of Shortage During COVID-19 Pandemic	5
Urine S-Adenosylmethionine are Related to Degree of Renal Insufficiency in Patients with Chronic Kidney Disease	5
Oncology Patients Who Develop Transfusion-Associated Circulatory Overload: An Observational Study	5
Evaluation of Transforming Growth Factor-β1 and Interleukin-35 Serum Levels in Patients with Placenta Accreta	5
Smudge Cells in Chronic Lymphocytic Leukemia: Pathophysiology, Laboratory Considerations, and Clinical Significance	5
Dysregulation of Long Noncoding RNANEAT1/miR-199a-5/BiP Axis in Patients with Diabetic Neuropathy	5
Urinary Exosomes: A Promising Biomarker for Disease Diagnosis	5
Looking into the Laboratory Staffing Issues that Affected Ambulatory Care Clinical Laboratory Operations during the COVID-19 Pandemic	5
Intravenous Immunoglobulin-Associated Hemolytic Anemia	5
EDTA-Induced Pseudothrombocytopenia up to 9 Months after Initial COVID-19 Infection Associated with Persistent Anti-SARS-CoV-2 IgM/IgG Seropositivity	5
Clinical Predictors of SARS-CoV-2 Testing Pressure on Clinical Laboratories: A Multinational Study Analyzing Google Trends and Over 100 Million Diagnostic Tests	5
Novel Methods for Detecting Human Cholesterol Crystals from Sampled Blood	5
A Rapid and Accurate Detection Approach for Multidrug-Resistant Tuberculosis Based on PCR-ELISA Microplate Hybridization Assay	5
Serum IL-6 and TNF-α Levels Are Correlated with Disease Severity in Patients with Ankylosing Spondylitis	5
Molecular Epidemiology of Carbapenem-Resistant Enterobacterales Strains Isolated from Blood Cultures in Antalya, Turkey	4
Transfusion Requirements and Blood Bank Support in Heart and Lung Transplantation	4
Determination of Glyphosate and AMPA in Blood Can Predict the Severity of Acute Glyphosate Herbicide Poisoning	4
Chemerin Levels in Acute Coronary Syndrome: Systematic Review and Meta-Analysis	4
Cell-Derived Microparticles in Blood Products from Blood Donors Deficient in Glucose-6-Phosphate Dehydrogenase	4
Cell-Derived Microparticles in Blood Products from Thalassemic Blood Donors	4
Incidence of Hepatotoxicity in Iranian Patients With HIV on Antiretroviral Therapies and Its Correlation with Virologic Response to HIV Treatment	4
Need for Confirmatory Neutralization Tests for Hepatitis B Surface Antigen Tests in Populations with Intermediate Prevalence	4
MALDI-TOF-MS Analysis in the Discovery and Identification of the Serum Peptide Pattern of Pancreatic Ductal Adenocarcinoma	4
T Cell Senescence by Extensive Phenotyping: An Emerging Feature of COVID-19 Severity	4
Novel PKD1 Mutations in Patients with Autosomal Dominant Polycystic Kidney Disease	4
The Association Between Serum Human Epididymis Protein 4 Level and Cardiovascular Events in Patients with Chronic Obstructive Pulmonary Disease	4
Clinical Value of Pepsinogen in the Screening, Prevention, and Diagnosis of Gastric Cancer	4
Quantitative Assessment of the Effects ofIL-1ß-511 C>T Variant on Breast Cancer Risk: An Updated Meta-Analysis of 3331 Cases and 3609 Controls	4
Elevated Kynurenine Levels in Patients with Primary Sjögren’s Syndrome	3

Modified Proline Metabolism and Prolidase Enzyme in COVID-19	3
Pancreatic Cancer Insights: Optimization of the Diagnostic Capacity of Tumor Biomarkers	3
Urinary MMP-7: A Predictive, Noninvasive Early Marker for Chronic Kidney Disease Development in Patients with Hypertension	3
Evaluation of RNA Isolation Methods in Human Adipose Tissue	3
Daratumumab Interference in Flow Cytometry Producing a False Kappa Light Chain Restriction in Plasma Cells	3
Association of SLC22A1,SLCO1B3 Drug Transporter Polymorphisms and Smoking with Disease Risk and Cytogenetic Response to Imatinib in Patients with Chronic Myeloid Leukemia	3
A Hemolytic Transfusion Reaction Caused by an Unexpected Leb Antibody	3
Blood Donors with Thalassemic Trait, Glucose-6-Phosphate Dehydrogenase Deficiency Trait, and Sickle Cell Trait and Their Blood Products: Current Status and Future Perspective	3
Trimethylamine-N-Oxide and Precursors as Novel Potential Biomarkers for Anxiety Disorder	3
Highly Sensitive Serum miRNA Panel for the Diagnosis of Hepatocellular Carcinoma in Egyptian Patients with HCV-Related HCC	3
Serum Ferritin Has Limited Prognostic Value on Mortality Risk in Patients with Decompensated Cirrhosis: A Propensity Score Matching Analysis	3
Association of CEA, NSE, CYFRA 21-1, SCC-Ag, and ProGRP with Clinicopathological Characteristics and Chemotherapeutic Outcomes of Lung Cancer	3
Whole-Exome Sequencing Reveals a Novel Mutation of FLNA Gene in an Iranian Family with Nonsyndromic Tetralogy of Fallot	3
Clinical Significance of Anti-Modified Citrullinated Vimentin Antibodies in Palindromic Rheumatism	3
Meteorin-like Protein and Asprosin Levels in Children and Adolescents with Obesity and Their Relationship with Insulin Resistance and Metabolic Syndrome	3
Pretreatment of Body Fluid Specimens Using Hyaluronidase and Ultracentrifugation	3
Variations in Nomenclature of Clinical Variants between Annotation Tools	3
Storage Duration and Red Blood Cell–Derived Microparticles in Packed Red Blood Cells Obtained from Donors with Thalassemia	3
Evaluation of the NG-Test CARBA 5 Kit for Rapid Detection of Carbapenemase Resistant Enterobacteriaceae	3
Strategies for Sustainability of University-Based Medical Laboratory Sciences Programs	3
Serum Leukocyte Cell-Derived Chemotaxin 2 (LECT2) Level Is Associated with Osteoporosis	3
Usage of Plasma Presepsin, C-Reactive Protein, Procalcitonin and Proadrenomedullin to Predict Bacteremia in Febril Neutropenia of Pediatric Hematological Malignancy Patients	3
A Literature Review on How We Can Address Medical Laboratory Scientist Staffing Shortages	3
Use of Self-Collected Saliva Samples for the Detection of SARS-CoV-2	3
Application of the Single-Molecule Real-Time Technology (SMRT) for Identification of HKαα Thalassemia Allele	3
Platelet MicroRNA-484 as a Novel Diagnostic Biomarker for Acute Coronary Syndrome	3
Rapid Molecular Detection for Differentiation of Homozygous HbE and ß0-Thalassemia/HbE in Samples Related With HbE >80% and Variable HbF Levels	3
Associations of Serum Pepsinogens and Helicobacter Pylori Infection with High-Sensitivity C-Reactive Protein in Medical Examination Population	3
Acquired FVII Deficiency and Acute Myeloid Leukemia: A Case Report and Literature Review	3
Diagnostic Value of Circular RNA hsa_circ_0002874 Expression in Peripheral Blood of Patients with Gastric Cancer	3
Validation of Two Revised, Simplified Criteria for Assessing Sepsis-Associated Disseminated Intravascular Coagulation in ICU Patients with Sepsis-3: A Retrospective Study	3
Effects of Cell-Derived Microparticles on Immune Cells and Potential Implications in Clinical Medicine	3
Evaluation of Polarized Light and Fluorescence Microscopy of Congo Red Stain in the Diagnosis of Renal Amyloidosis	3
Lean Principles to Improve Quality in High-Throughput COVID-19 Testing Using SwabSeq: A Barcoded Sequencing-Based Testing Platform	2
Cutoff Value of Qualitative HBsAg for Confirmatory HBsAg Using the Chemiluminescence Microparticle Immunoassay Method	2
Urine Protein Immunofixation Electrophoresis: Free Light Chain Urine Immunofixation Electrophoresis Is More Sensitive than Conventional Assays for Detecting Monoclonal Light Chains and Could Serve as	2
Anti-S Antibody: A Rare Cause of Fetal Hydrops in a Previously Sensitized Mother	2
Pathology—The Beginnings of Laboratory Medicine	2
Accurate Quantification of Monoclonal Immunoglobulins Migrating in the Beta Region on Protein Electrophoresis	2
Using the BDFX40 Automated Continuous Blood Culture System to Isolate and RecoverStreptobacillus moniliformisin the Presence of 0.05% SPS: A 55-Year, 56-Strain Retrospective Study	2
Circulating Levels of C1q/TNF-Related Protein 3 (CTRP3) and CTRP9 in Gestational Diabetes and Their Association with Insulin Resistance and Inflammatory Cytokines	2
SARS-CoV-2 Antibody Testing: Where Are We Now?	2
Clinical Value of Detecting Anti-Mutated Citrullinated Vimentin, Anti-Cyclic Citrullinated Peptide, Red Cell Distribution Width and 25-Hydroxyvitamin D in the Diagnosis of Rheumatoid Arthritis	2
Sialic Acid as a Suitable Marker of Clinical Disease Activity in Patients with Crohn’s Disease	2
Oxidative Stress Levels and Dynamic Thiol-Disulfide Balance in Preterm Newborns with Bronchopulmonary Dysplasia	2
The Utility of Elevated Serum Lactate Dehydrogenase in Current Clinical Practice	2
Evaluation of RT-LAMP Assay for Rapid Detection of SARS-CoV-2	2
N-Terminal Prohormone Brain Natriuretic Peptide as a Prognostic Biomarker for the Risk of Complications in Type 2 Diabetes: A Systematic Review and Meta-Analysis	2
Unexpected Cholera Bacteremia in a 91 Year Old Caucasian Male Patient	2
HbA1c Below the Reportable Range	2
D-Dimer Combined With CRP Can Improve the Differential Value of Bacterial Meningitis and Tuberculous Meningitis	2
Mycoplasma hominis Meningitis Diagnosed by Metagenomic Next-Generation Sequencing in a Preterm Newborn: a Case Report and Literature Review	2
Protocols to Dissolve Amorphous Urate Crystals in Urine	2
Laboratory Assay Evaluation Demystified: A Review of Key Factors Influencing Interpretation of Test Results Using Different Assays for SARS-CoV-2 Infection Diagnosis	2
High C-Reactive Protein-to-Lymphocyte Ratio Is Predictive of Unfavorable Prognosis in HBV-Associated Decompensated Cirrhosis	2
Whole-Exome Sequencing Identifies a Recurrent Small In-Frame Deletion in MYO15A Causing Autosomal Recessive Nonsyndromic Hearing Loss in 3 Iranian Pedigrees	2
Comparison between the Sofia SARS Antigen FIA Test and the PCR Test in Detection of SARS-CoV-2 Infection	2
The Diagnostic Performance of lncRNAs from Blood Specimens in Patients with Hepatocellular Carcinoma: A Meta-Analysis	2
Anti-Saccharomyces cerevisiae Antibodies in Rheumatoid Arthritis	2
Evaluation of Intra- and Interlaboratory Variations in SARS-CoV-2 Real-Time RT-PCR Through Nationwide Proficiency Testing	2
Metabolomics: A New Tool to Reveal the Nature of Diabetic Kidney Disease	2
Reliable Detection of T-Cell Clonality by Flow Cytometry in Mature T-Cell Neoplasms Using TRBC1: Implementation as a Reflex Test and Comparison with PCR-Based Clonality Testing	2
A Novel Mutation of the Membrane Metallo-Endopeptidase Gene Related to Late-Onset Hereditary Polyneuropathy: Case Report and Review of the Literature	2
Consistency Between Thyrotropin Receptor Antibody (TRAb) and Thyroid-Stimulating Antibody (TSAb) Levels in Patients with Graves Disease	2
Macroprolactinoma-Induced Syndrome of Inappropriate Antidiuresis and Its Reversal with Dopamine Agonist Therapy	2
Achondroplasia—First Report from India of a Rare FGFR3 Gene Variant	2
The Viability of Hematopoietic Progenitor Cell Grafts after Cryopreservation Does Not Predict Delayed Engraftment in Allogeneic Hematopoietic Stem Cell Transplantation	2
Lymphocyte Aggregation in Low-Grade B-Cell Lymphoma	2
COVID-19 Pandemic Once Again Exposes the Weakest Link in Laboratory Services: Specimen Delivery	2
A Novel USP25::PDGFRA Gene Fusion in a 78 Year Old Patient with a Myeloid Neoplasm	2
Methods to Correct Drug-Induced Coagulopathy in Bleeding Emergencies: A Comparative Review	2
ABL Kinase Domain Mutations in Iranian Chronic Myeloid Leukemia Patients with Resistance to Tyrosine Kinase Inhibitors	2
An Assessment of Gender Equity and Parity Among “Nontraditional” Pathology Awards	2