Brain

Papers
(The TQCC of Brain is 18. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-02-01 to 2024-02-01.)
ArticleCitations
The emerging spectrum of COVID-19 neurology: clinical, radiological and laboratory findings794
Brain-first versus body-first Parkinson’s disease: a multimodal imaging case-control study364
Microglial exosomes facilitate α-synuclein transmission in Parkinson’s disease241
COVID-19 neuropathology at Columbia University Irving Medical Center/New York Presbyterian Hospital228
Cognitive impairment and altered cerebral glucose metabolism in the subacute stage of COVID-19223
Cerebrovascular disease in patients with COVID-19: neuroimaging, histological and clinical description208
Impaired glymphatic function and clearance of tau in an Alzheimer’s disease model202
Development and validation of an interpretable deep learning framework for Alzheimer’s disease classification202
Epidemiological and cohort study finds no association between COVID-19 and Guillain-Barré syndrome199
Plasma tau, neurofilament light chain and amyloid-β levels and risk of dementia; a population-based cohort study178
Plasma GFAP is an early marker of amyloid-β but not tau pathology in Alzheimer’s disease173
MRI signatures of brain age and disease over the lifespan based on a deep brain network and 14 468 individuals worldwide170
Consensus on the reporting and experimental design of clinical and cognitive-behavioural neurofeedback studies (CRED-nf checklist)164
Post-stroke deficit prediction from lesion and indirect structural and functional disconnection162
Myelin oligodendrocyte glycoprotein antibody-associated disease: an immunopathological study159
Phosphorylated tau interactome in the human Alzheimer’s disease brain157
Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state154
Neurofilaments: neurobiological foundations for biomarker applications153
Medial temporal lobe connectivity and its associations with cognition in early Alzheimer’s disease151
Two distinct neuroanatomical subtypes of schizophrenia revealed using machine learning145
Recommendations to distinguish behavioural variant frontotemporal dementia from psychiatric disorders143
18F-MK-6240 PET for early and late detection of neurofibrillary tangles139
Longitudinal plasma p-tau217 is increased in early stages of Alzheimer’s disease136
Sleep deprivation impairs molecular clearance from the human brain134
Definitions and classification of malformations of cortical development: practical guidelines133
Bidirectional gut-to-brain and brain-to-gut propagation of synucleinopathy in non-human primates130
Cerebellar ataxia, neuropathy, vestibular areflexia syndrome due to RFC1 repeat expansion130
Tissue-resident memory T cells invade the brain parenchyma in multiple sclerosis white matter lesions123
Alzheimer’s disease brain-derived extracellular vesicles spread tau pathology in interneurons123
Time course of phosphorylated-tau181 in blood across the Alzheimer’s disease spectrum119
Long-term evolution of multiple sclerosis iron rim lesions in 7 T MRI115
Untangling the association of amyloid-β and tau with synaptic and axonal loss in Alzheimer’s disease114
CD8 T cell nigral infiltration precedes synucleinopathy in early stages of Parkinson’s disease111
CD4 T cells mediate brain inflammation and neurodegeneration in a mouse model of Parkinson's disease111
Clinical and experimental insight into pathophysiology, comorbidity and therapy of absence seizures110
The role of gut dysbiosis in Parkinson’s disease: mechanistic insights and therapeutic options108
How patients with multiple sclerosis acquire disability105
Diabetes medications and risk of Parkinson’s disease: a cohort study of patients with diabetes102
White matter abnormalities across different epilepsy syndromes in adults: an ENIGMA-Epilepsy study102
Microglial activation and tau burden predict cognitive decline in Alzheimer’s disease101
Dynamics of language reorganization after left temporo-parietal and frontal stroke100
Mitochondrial damage-associated inflammation highlights biomarkers in PRKN/PINK1 parkinsonism99
Beneficial effects of autologous mesenchymal stem cell transplantation in active progressive multiple sclerosis99
Neurovascular injury with complement activation and inflammation in COVID-1995
Acute and chronic neurological disorders in COVID-19: potential mechanisms of disease94
18F-flortaucipir PET to autopsy comparisons in Alzheimer’s disease and other neurodegenerative diseases94
Comorbid neuropathological diagnoses in early versus late-onset Alzheimer’s disease93
The potential of serum neurofilament as biomarker for multiple sclerosis93
The role of genetics in Parkinson’s disease: a large cohort study in Chinese mainland population92
Relationship between cortical iron and tau aggregation in Alzheimer’s disease91
Redefining the multidimensional clinical phenotypes of frontotemporal lobar degeneration syndromes90
Emerging roles for dynamic aquaporin-4 subcellular relocalization in CNS water homeostasis89
Recalibrating the epigenetic clock: implications for assessing biological age in the human cortex89
Acute and non-resolving inflammation associate with oxidative injury after human spinal cord injury89
Alpha-synuclein seeds in olfactory mucosa of patients with isolated REM sleep behaviour disorder86
Prognosis for patients with cognitive motor dissociation identified by brain-computer interface86
Genetic variants and functional pathways associated with resilience to Alzheimer’s disease86
Pathophysiological subtypes of Alzheimer’s disease based on cerebrospinal fluid proteomics84
NLRP3 inflammasome as prognostic factor and therapeutic target in primary progressive multiple sclerosis patients84
Natural history of motor symptoms in Parkinson’s disease and the long-duration response to levodopa83
To what degree is late life cognitive decline driven by age-related neuropathologies?82
Head-to-head comparison of 10 plasma phospho-tau assays in prodromal Alzheimer’s disease82
Hearing and dementia: from ears to brain78
Functional cognitive disorder: dementia’s blind spot76
CSF tau microtubule binding region identifies tau tangle and clinical stages of Alzheimer’s disease76
COVID-19 vaccine and Guillain-Barré syndrome: let’s not leap to associations75
Quantitative magnetic resonance imaging towards clinical application in multiple sclerosis75
The GGC repeat expansion inNOTCH2NLCis associated with oculopharyngodistal myopathy type 374
Detection of neuron-derived pathological α-synuclein in blood74
In vivo CRISPRa decreases seizures and rescues cognitive deficits in a rodent model of epilepsy74
Depression, dementia and immune dysregulation74
Basal forebrain volume reliably predicts the cortical spread of Alzheimer’s degeneration74
Developmental and epileptic encephalopathies: what we do and do not know73
Gut metagenomics-derived genes as potential biomarkers of Parkinson’s disease72
A clinical-radiological framework of the right temporal variant of frontotemporal dementia72
Predicting future rates of tau accumulation on PET70
Pharmacological SARM1 inhibition protects axon structure and function in paclitaxel-induced peripheral neuropathy70
Ageing promotes pathological alpha-synuclein propagation and autonomic dysfunction in wild-type rats70
Painful and non-painful diabetic neuropathy, diagnostic challenges and implications for future management70
The synapse in traumatic brain injury70
Early stages of tau pathology and its associations with functional connectivity, atrophy and memory69
Studying human nociceptors: from fundamentals to clinic69
Corticospinal-motor neuronal plasticity promotes exercise-mediated recovery in humans with spinal cord injury69
The development and convergence of co-pathologies in Alzheimer’s disease69
The role of noradrenaline in cognition and cognitive disorders69
Variants in saposin D domain of prosaposin gene linked to Parkinson’s disease68
Brain TSPO-PET predicts later disease progression independent of relapses in multiple sclerosis68
The extracellular matrix as modifier of neuroinflammation and remyelination in multiple sclerosis68
Network degeneration in Parkinson’s disease: multimodal imaging of nigro-striato-cortical dysfunction67
Distinct responses of neurons and astrocytes to TDP-43 proteinopathy in amyotrophic lateral sclerosis67
The microglial component of amyotrophic lateral sclerosis67
Distinctive binding properties of human monoclonal LGI1 autoantibodies determine pathogenic mechanisms66
Acute ischaemic stroke alters the brain’s preference for distinct dynamic connectivity states66
Diffuse axonal injury predicts neurodegeneration after moderate–severe traumatic brain injury63
Segregation of functional networks is associated with cognitive resilience in Alzheimer’s disease62
Glymphatic system impairment in multiple sclerosis: relation with brain damage and disability62
Local sleep-like cortical reactivity in the awake brain after focal injury62
An MRI radiomics approach to predict survival and tumour-infiltrating macrophages in gliomas62
Increased perception-action binding in Tourette syndrome62
Models of psychedelic drug action: modulation of cortical-subcortical circuits61
Consciousness among delta waves: a paradox?61
Neuroinflammation and protein aggregation co-localize across the frontotemporal dementia spectrum61
CYLD is a causative gene for frontotemporal dementia – amyotrophic lateral sclerosis61
A genetic link between risk for Alzheimer's disease and severe COVID-19 outcomes via the OAS1 gene60
Plasma markers predict changes in amyloid, tau, atrophy and cognition in non-demented subjects60
The accumulation rate of tau aggregates is higher in females and younger amyloid-positive subjects60
Modulation of beta bursts in subthalamic sensorimotor circuits predicts improvement in bradykinesia59
Diagnostic value of cerebrospinal fluid alpha-synuclein seed quantification in synucleinopathies59
Recent progress in translational engineeredin vitromodels of the central nervous system59
The spatiotemporal changes in dopamine, neuromelanin and iron characterizing Parkinson’s disease59
Reduced oligodendrocyte exosome secretion in multiple system atrophy involves SNARE dysfunction58
Detecting axonal injury in individual patients after traumatic brain injury58
Damage to Broca’s area does not contribute to long-term speech production outcome after stroke57
RFC1 expansions are a common cause of idiopathic sensory neuropathy57
A catalogue of new incidence estimates of monogenic neurodevelopmental disorders caused by de novo variants57
Dopaminergic imaging and clinical predictors for phenoconversion of REM sleep behaviour disorder57
Psychosis in neurodegenerative disease: differential patterns of hallucination and delusion symptoms56
Early childhood epilepsies: epidemiology, classification, aetiology, and socio-economic determinants56
Stage-specific links between plasma neurofilament light and imaging biomarkers of Alzheimer’s disease56
Genotype-phenotype correlations in SCN8A-related disorders reveal prognostic and therapeutic implications56
Myelin and axon pathology in multiple sclerosis assessed by myelin water and multi-shell diffusion imaging55
Molecular signature of slowly expanding lesions in progressive multiple sclerosis55
Sleep and longitudinal cognitive performance in preclinical and early symptomatic Alzheimer’s disease55
Structural and functional footprint of visual snow syndrome54
Evolution of neuroinflammation across the lifespan of individuals with Down syndrome54
Microglial activation and blood–brain barrier permeability in cerebral small vessel disease53
Spatiotemporal changes in substantia nigra neuromelanin content in Parkinson’s disease53
The apparently milder course of multiple sclerosis: changes in the diagnostic criteria, therapy and natural history53
GABA and glutamate deficits from frontotemporal lobar degeneration are associated with disinhibition53
Repetitive transcranial magnetic stimulation for neuropathic pain: a randomized multicentre sham-controlled trial53
Macrophage phagocytosis after spinal cord injury: when friends become foes52
Baseline reward processing and ventrostriatal dopamine function are associated with pramipexole response in depression52
Reactive microglia enhance the transmission of exosomal α-synuclein via toll-like receptor 251
COVID-19 induces CNS cytokine expression and loss of hippocampal neurogenesis51
Regional locus coeruleus degeneration is uncoupled from noradrenergic terminal loss in Parkinson’s disease51
COVID-19 vaccination and Guillain-Barré syndrome: analyses using the National Immunoglobulin Database51
Blunted medial prefrontal cortico-limbic reward-related effective connectivity and depression51
Long-term post-mortem studies following neurturin gene therapy in patients with advanced Parkinson’s disease51
KMT2B-related disorders: expansion of the phenotypic spectrum and long-term efficacy of deep brain stimulation51
Driving motor cortex oscillations modulates bradykinesia in Parkinson’s disease50
Precision medicine in stroke: towards personalized outcome predictions using artificial intelligence49
Splicing machinery dysregulation drives glioblastoma development/aggressiveness: oncogenic role of SRSF349
Sex effects on brain structure in de novo Parkinson’s disease: a multimodal neuroimaging study49
Modelling and treating GRIN2A developmental and epileptic encephalopathy in mice49
Diffuse axonal injury has a characteristic multidimensional MRI signature in the human brain49
SomaticMAP3K3andPIK3CAmutations in sporadic cerebral and spinal cord cavernous malformations49
Longitudinal neuroimaging biomarkers differ across Alzheimer’s disease phenotypes49
Dystonia genes functionally converge in specific neurons and share neurobiology with psychiatric disorders48
Tau immunophenotypes in chronic traumatic encephalopathy recapitulate those of ageing and Alzheimer’s disease48
O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease48
Disease-modifying drugs can reduce disability progression in relapsing multiple sclerosis47
Epilepsy subtype-specific copy number burden observed in a genome-wide study of 17 458 subjects47
Sequence of clinical and neurodegeneration events in Parkinson’s disease progression47
Stop that! It’s not Tourette’s but a new type of mass sociogenic illness47
A unified model of post-stroke language deficits including discourse production and their neural correlates47
Cross-frequency coupling between gamma oscillations and deep brain stimulation frequency in Parkinson’s disease47
Dopamine-dependent early synaptic and motor dysfunctions induced by α-synuclein in the nigrostriatal circuit47
Locus coeruleus integrity and the effect of atomoxetine on response inhibition in Parkinson’s disease46
Network localization of clinical, cognitive, and neuropsychiatric symptoms in Alzheimer’s disease46
Brain-derived tau: a novel blood-based biomarker for Alzheimer’s disease-type neurodegeneration46
rs34331204 regulates TSPAN13 expression and contributes to Alzheimer’s disease with sex differences46
A novel RFC1 repeat motif (ACAGG) in two Asia-Pacific CANVAS families46
From biomechanics to pathology: predicting axonal injury from patterns of strain after traumatic brain injury45
Novel congenital disorder of O-linked glycosylation caused by GALNT2 loss of function45
APOE4 derived from astrocytes leads to blood–brain barrier impairment45
Dopamine and reward hypersensitivity in Parkinson’s disease with impulse control disorder45
Soluble TREM2 is elevated in Parkinson’s disease subgroups with increased CSF tau45
Genetic, cellular, and connectomic characterization of the brain regions commonly plagued by glioma45
Cortical disinhibition in Parkinson’s disease44
Post-stroke outcomes predicted from multivariate lesion-behaviour and lesion network mapping44
Brain responsivity provides an individual readout for motor recovery after stroke44
Towards network-guided neuromodulation for epilepsy44
Improved relapse recovery in paediatric compared to adult multiple sclerosis44
Opening of ATP sensitive potassium channels causes migraine attacks with aura44
Sex-dependent autosomal effects on clinical progression of Alzheimer’s disease44
Variant-specific changes in persistent or resurgent sodium current in SCN8A-related epilepsy patient-derived neurons44
Severe COVID-19-related encephalitis can respond to immunotherapy43
Limbic-predominant age-related TDP-43 encephalopathy differs from frontotemporal lobar degeneration43
Reimagining cholinergic therapy for Alzheimer’s disease43
Longitudinal 18F-MK-6240 tau tangles accumulation follows Braak stages43
Towards realizing the vision of precision medicine: AI based prediction of clinical drug response43
New genotype-phenotype correlations in a large European cohort of patients with sarcoglycanopathy43
Loss of TMEM106B leads to myelination deficits: implications for frontotemporal dementia treatment strategies42
Protein contributions to brain atrophy acceleration in Alzheimer’s disease and primary age-related tauopathy42
Precuneus magnetic stimulation for Alzheimer’s disease: a randomized, sham-controlled trial42
5′ UTR CGG repeat expansion inGIPC1is associated with oculopharyngodistal myopathy42
Beyond the average patient: how neuroimaging models can address heterogeneity in dementia42
Riluzole, a glutamate modulator, slows cerebral glucose metabolism decline in patients with Alzheimer’s disease42
Cortical hypometabolism reflects local atrophy and tau pathology in symptomatic Alzheimer’s disease41
A daily temperature rhythm in the human brain predicts survival after brain injury41
Comparative connectivity correlates of dystonic and essential tremor deep brain stimulation41
Antibodies to the Caspr1/contactin-1 complex in chronic inflammatory demyelinating polyradiculoneuropathy41
Central opioid receptors mediate morphine-induced itch and chronic itch via disinhibition41
A Māori specific RFC1 pathogenic repeat configuration in CANVAS, likely due to a founder allele41
The neuroethics of disorders of consciousness: a brief history of evolving ideas40
Subthalamic nucleus activity dynamics and limb movement prediction in Parkinson’s disease40
Transcranial alternating current stimulation for treating depression: a randomized controlled trial40
Neuropathological correlates of cortical superficial siderosis in cerebral amyloid angiopathy40
Platelet-derived growth factor beta is a potent inflammatory driver in paediatric high-grade glioma40
Closed-loop stimulation of the medial septum terminates epileptic seizures40
Imaging meningeal inflammation in CNS autoimmunity identifies a therapeutic role for BTK inhibition40
Brain cancer induces systemic immunosuppression through release of non-steroid soluble mediators40
BACE inhibition causes rapid, regional, and non-progressive volume reduction in Alzheimer’s disease brain39
The structural connectome and motor recovery after stroke: predicting natural recovery39
Slow blood-to-brain transport underlies enduring barrier dysfunction in American football players39
α-Synuclein oligomers in skin biopsy of idiopathic and monozygotic twin patients with Parkinson’s disease39
Anti-amyloid antibody therapies in Alzheimer’s disease39
Structural white matter connectometry of word production in aphasia: an observational study39
Multimodal neuroimaging in post-COVID syndrome and correlation with cognition39
Cognitive load amplifies Parkinson’s tremor through excitatory network influences onto the thalamus38
Propagated α-synucleinopathy recapitulates REM sleep behaviour disorder followed by parkinsonian phenotypes in mice38
Distinct patterns of structural damage underlie working memory and reasoning deficits after traumatic brain injury38
Cardiovascular brain impulses in Alzheimer’s disease38
The multifaceted role of kinases in amyotrophic lateral sclerosis: genetic, pathological and therapeutic implications38
Molecular and cellular correlates of human nerve regeneration: ADCYAP1/PACAP enhance nerve outgrowth38
A new science of emotion: implications for functional neurological disorder38
Persistent white matter changes in recovered COVID-19 patients at the 1-year follow-up38
Regional brain iron and gene expression provide insights into neurodegeneration in Parkinson’s disease38
Impaired theta phase coupling underlies frontotemporal dysconnectivity in schizophrenia37
Three-dimensional analysis of synaptic organization in the hippocampal CA1 field in Alzheimer’s disease37
Bacterial neurotoxic metabolites in multiple sclerosis cerebrospinal fluid and plasma37
Spreading depolarizations in ischaemia after subarachnoid haemorrhage, a diagnostic phase III study37
Functional maps of direct electrical stimulation-induced speech arrest and anomia: a multicentre retrospective study37
In vivo stress granule misprocessing evidenced in a FUS knock-in ALS mouse model37
The gain of function SCN1A disorder spectrum: novel epilepsy phenotypes and therapeutic implications37
Preventing amyotrophic lateral sclerosis: insights from pre-symptomatic neurodegenerative diseases37
Autoimmune encephalitis mediated by B-cell response against N-methyl-d-aspartate receptor36
Quantitative spinal cord MRI in MOG-antibody disease, neuromyelitis optica and multiple sclerosis36
Mitochondrial UQCRC1 mutations cause autosomal dominant parkinsonism with polyneuropathy36
UNC13B variants associated with partial epilepsy with favourable outcome36
Motor and cognitive outcomes of cerebello-spinal stimulation in neurodegenerative ataxia36
Guillain-Barré syndrome after SARS-CoV-2 infection in an international prospective cohort study36
Progression is independent of relapse activity in early multiple sclerosis: a real-life cohort study36
RNA profiling of human dorsal root ganglia reveals sex differences in mechanisms promoting neuropathic pain35
Spatiotemporal features of β-γ phase-amplitude coupling in Parkinson’s disease derived from scalp EEG35
Differential medication overuse risk of novel anti-migraine therapeutics35
Allosteric modulation of NMDA receptors prevents the antibody effects of patients with anti-NMDAR encephalitis35
Dissecting autism and schizophrenia through neuroimaging genomics35
Activation of Wnt/β-catenin pathway mitigates blood–brain barrier dysfunction in Alzheimer’s disease35
Unravelling the enigma of cortical tremor and other forms of cortical myoclonus35
Staging of astrocytopathy and complement activation in neuromyelitis optica spectrum disorders35
Gene variant effects across sodium channelopathies predict function and guide precision therapy35
Intrinsic blood–brain barrier dysfunction contributes to multiple sclerosis pathogenesis34
Deep brain stimulation modulates directional limbic connectivity in obsessive-compulsive disorder34
SLC12A2 variants cause a neurodevelopmental disorder or cochleovestibular defect34
Natural history of Charcot-Marie-Tooth disease type 2A: a large international multicentre study34
Assessing the landscape of STXBP1-related disorders in 534 individuals34
Morphometric network differences in ageing versus Alzheimer’s disease dementia34
Cortical interneuron-mediated inhibition delays the onset of amyotrophic lateral sclerosis34
Astrocyte–neuron interplay is critical for Alzheimer's disease pathogenesis and is rescued by TRPA1 channel blockade34
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