Brain

Article	Citations
Reply: Is postural tachycardia syndrome a psychogenic disorder?; Notes on establishing fear conditioning as causal in the postural orthostatic tachycardia syndrome; Patients with POTS fear that data o	373
Clinical dimensions along the non-fluent variant primary progressive aphasia spectrum	338
Correction to: Variants in the SK2 channel gene (KCNN2) lead to dominant neurodevelopmental movement disorders	329
Methodological drawbacks in the alleged association between foetal sonographic anomalies and autism	183
Biallelic ADAM22 pathogenic variants cause progressive encephalopathy and infantile-onset refractory epilepsy	181
Genetically identical twin-pair difference models support the amyloid cascade hypothesis	180
Optogenetic stimulation of the superior colliculus suppresses genetic absence seizures	177
Gain-of-function and loss-of-function variants in GRIA3 lead to distinct neurodevelopmental phenotypes	177
De novo variants in ATXN7L3 lead to developmental delay, hypotonia and distinctive facial features	177
The axon initial segment as a source of neuropathic pain	176
Clinical and genetic spectrum of 355 Chinese children with epilepsy: a trio-sequencing-based study	170
Choroid plexus mis-splicing and altered cerebrospinal fluid composition in myotonic dystrophy type 1	164
Clinical and genetic characterization of a progressive RBL2-associated neurodevelopmental disorder	163
Deep brain stimulation: a tale of two targets … and closing the loop	159
Trigeminal nerve microstructure is linked with neuroinflammation and brainstem activity in migraine	153
Dysregulated cortical excitability and tau phosphorylation in a β3 integrin mouse model of autism	151
Mapping the peripheral immune landscape of Parkinson’s disease patients with single-cell sequencing	148
Genetic evaluation of dementia with Lewy bodies implicates distinct disease subgroups	147
We’re all in this together: a rejoinder to Masud Husain’s (rant) editorial	138
Biallelic FRA10AC1 variants cause a neurodevelopmental disorder with growth retardation	136
Somatic variants of MAP3K3 are sufficient to cause cerebral and spinal cord cavernous malformations	136
Lesion correlates of impaired acoustic-phonetic perception after unilateral left hemisphere stroke	134
Cerebral amyloid angiopathy interacts with neuritic amyloid plaques to promote tau and cognitive decline	130
The inferior fronto-occipital fasciculus: bridging phylogeny, ontogeny and functional anatomy	129
Thalamostriatal disconnection underpins long-term seizure freedom in frontal lobe epilepsy surgery	128

3T MRI of rapid brain activity changes driven by subcallosal cingulate deep brain stimulation	122
Speech and language markers of neurodegeneration: a call for global equity	120
Impaired ribosome-associated quality control of C9orf72 arginine-rich dipeptide-repeat proteins	120
Brain repair mechanisms after cell therapy for stroke	118
‘Seeding’ the idea of early diagnostics in synucleinopathies	113
A data-driven study of Alzheimer's disease related amyloid and tau pathology progression	112
Distinct subcellular autophagy impairments in induced neurons from patients with Huntington's disease	104
18F-MK-6240 tau-PET in genetic frontotemporal dementia	104
From bugs to brain: unravelling the GABA signalling networks in the brain–gut–microbiome axis	102
The use of optical coherence tomography in neurology: a review	97
‘Hippocampal innate inflammatory gliosis only’ in pharmacoresistant temporal lobe epilepsy	95
Associations between accelerated forgetting, amyloid deposition and brain atrophy in older adults	94
Peripherin is a biomarker of axonal damage in Guillain-Barré syndrome: a pathophysiological annotation	93
The vascular contribution of apolipoprotein E to Alzheimer’s disease	92
Source-sink connectivity: a novel interictal EEG marker for seizure localization	92
Diffusion MRI tracks cortical microstructural changes during the early stages of Alzheimer’s disease	90
ActivatingRAC1variants in the switch II region cause a developmental syndrome and alter neuronal morphology	89
Dysfunction of the magnocellular subdivision of the visual thalamus in developmental dyslexia	88
Brain cholesterol and Alzheimer's disease: challenges and opportunities in probe and drug development	87
Correction to: New genotype-phenotype correlations in a large European cohort of patients with sarcoglycanopathy	87
Reply: Unblinding in the lecanemab trial in Alzheimer’s disease	86
Hitching a ride on exosomes: a new approach for the delivery of siRNA-mediated therapies	86
Demystifying interictal discharges and seizure initiation in focal epilepsy	86
Activation and sensitization of meningeal nociceptors by PACAP-38: implications for migraine headache	85
Multiple lines of evidence for disruption of nuclear lamina and nucleoporins in FUS amyotrophic lateral sclerosis	85
Structural covariance analysis for neurodegenerative and neuroinflammatory brain disorders	84
Defective lipid signalling caused by mutations inPIK3C2Bunderlies focal epilepsy	84
Biallelic null variants in PNPLA8 cause microcephaly by reducing the number of basal radial glia	83
Molecular and clinical spectrum of epilepsy-dyskinesia syndromes: a cross-sectional study of 609 patients	81
Integrative miRNA–mRNA profiling of human epidermis: unique signature of SCN9A painful neuropathy	81
Clinical features and prognostic factors in adults with brain abscess	81
Multicentre analysis of seizure outcome predicted by removal of high-frequency oscillations	79
Hippocampal synaptic failure is an early event in experimental parkinsonism with subtle cognitive deficit	79
Stuttering associated with a pathogenic variant in the chaperone protein cyclophilin 40	79
Long-term neuropsychological trajectories in children with epilepsy: does surgery halt decline?	78
Loss-of-function variants inMYCBP2cause neurobehavioural phenotypes and corpus callosum defects	78
Clinical and MRI measures to identify non-acute MOG-antibody disease in adults	78
The three deceits of bureaucracy	77
Extra-cranial cholinergic lesions in dementia with Lewy bodies	77
Cytotoxic T cells and plasma cells dominate early in temporal lobe epilepsy with GAD antibodies	76
Evolutionary perspectives on mRNA signatures of neurodegeneration-related brain remodelling	76
New mechanistic insights into hereditary spastic paraplegias	75
GGC repeat expansions in NOTCH2NLC cause uN2CpolyG cerebral amyloid angiopathy	75
Functional network reorganization precedes apathy in Parkinson’s disease: a neural marker of risk?	74
The interictal suppression hypothesis is the dominant differentiator of seizure onset zones in focal epilepsy	73
The low dimensionality of post-stroke cognitive deficits: it’s the lesion anatomy!	73
Preclinical type 2 diabetes mellitus subtypes: new insights into diabetes, depression and dementia	73
Periventricular remyelination failure in multiple sclerosis: a substrate for neurodegeneration	71
Midbrain cytotoxic T cells as a distinct neuropathological feature of progressive supranuclear palsy	71
Genome-wide association study of neuropathological features in Lewy body disease	71

The spectrum of disease and tau pathology of nodding syndrome in Uganda	71
Disruption of DNA methylation underpins the neuroinflammation induced by targeted CNS radiotherapy	70
Multiple sclerosis in Denmark (1950–2023): mean age, sex distribution, incidence and prevalence	69
Treatment resistant recurrent unipolar and bipolar depression: associative learning abnormalities	69
Deciphering the impact of coding and non-coding SCN1A gene variants on RNA splicing	68
How COVID-19 affects microvessels in the brain	68
Cross-seeding by prion protein inactivates TDP-43	66
Multifaceted nanoparticles: emerging mechanisms and therapies in neurodegenerative diseases	65
Synaptic dysregulation in a mouse model of GRIN2D developmental and epileptic encephalopathy	65
Biallelic LGI1 and ADAM23 variants cause hippocampal epileptic encephalopathy via the LGI1–ADAM22/23 pathway	65
Loss of DOT1L disrupts neuronal transcription and leads to a neurodevelopmental disorder	65
Extracellular vesicle biomarkers for complement dysfunction in schizophrenia	64
A generalizable data-driven model of atrophy heterogeneity and progression in memory clinic settings	64
Multimodal mapping of regional brain vulnerability to focal cortical dysplasia	64
Novel insight into TRPV1-induced mitochondrial dysfunction in neuropathic pain	63
Integrative genomics reveals pathogenic mediator of valproate-induced neurodevelopmental disability	63
Clinically relevant mitochondrial-targeted therapy improves chronic outcomes after traumatic brain injury	62
Correction to: Blood–brain barrier opening of the default mode network in Alzheimer's disease with magnetic resonance-guided focused ultrasound	61
Neural stem cell therapies for spinal cord injury repair: an update on recent preclinical and clinical advances	61
How modular are modules in visual cortex?	61
A sensory neuron-specific long non-coding RNA reduces neuropathic pain by rescuing KCNN1 expression	61
From shadows to spotlight: the evolution of migraine stigma since the 17th century	60
Correction to: Sex-specific modulation of amyloid-β on tau phosphorylation underlies faster tangle accumulation in females	60
Correction to: Expanded clinical phenotype spectrum correlates with variant function in SCN2A-related disorders	58
Untangling white matter fibre changes in Alzheimer's disease and small vessel disease	58
A novel eye-movement impairment in multiple sclerosis indicating widespread cortical damage	58
Sorting out Parkinson’s disease: one cell at a time	58
Corrigendum to: Imaging protein aggregates in the serum and cerebrospinal fluid in Parkinson’s disease	58
JC virus spread is potentiated by glial replication and demyelination-linked glial proliferation	58
A journey towards the pot of gold	57
Reply: The correlation of behavioural deficits post-stroke: a trivial issue?	57
Delineation of functionally essential protein regions for 242 neurodevelopmental genes	56
Random forest: random results or meaningful insights for patients with facioscapulohumeral muscular dystrophy?	56
Reply: Do we need new MRI criteria for the diagnosis of radiologically isolated syndrome?	56
Reply: Lecanemab: turning point, or status quo? An ethics perspective	56
Neuromelanin as a nidus for neurodegeneration	56
Wheelchair use in genetically confirmed FSHD1 from a large cohort study in Chinese population	55
Endosomal 2Cl−/H+ exchangers regulate neuronal excitability by tuning Kv7/KCNQ channel density	55
Sleep and seizure risk in epilepsy: bed and wake times are more important than sleep duration	55
Repeat conformation heterogeneity in cerebellar ataxia, neuropathy, vestibular areflexia syndrome	55
Early onset hereditary neuronopathies: an update on non-5qmotor neuron diseases	54
Genetic variability in sporadic amyotrophic lateral sclerosis	54
Multicompartmental models and diffusion abnormalities in paediatric mild traumatic brain injury	54
White matter connections within the central sulcus subserving the somato-cognitive action network	54
Amyloid-β predominant Alzheimer’s disease neuropathologic change	54
Misdirected yet intact TREX1 exonuclease activity causes human cerebral and systemic small vessel disease	54
Occludin modulates HIV and ischaemic stroke response via mitochondrial antiviral signalling pathway	54
In silico versus functional characterization of genetic variants: lessons from muscle channelopathies	53
Anatomo-functional basis of emotional and motor resonance elicited by facial expressions	53
Motor neuron TDP-43 proteinopathy in progressive supranuclear palsy and corticobasal degeneration	53
Age-related and amyloid-beta-independent tau deposition and its downstream effects	53
Plasma VEGFA and PGF impact longitudinal tau and cognition in preclinical Alzheimer’s disease	52
Role of CD5 signalling for pro-inflammatory Th17 response in multiple sclerosis	52
Large-scale rare variant burden testing in Parkinson's disease	52
Interferon-γ controls aquaporin 4-specific Th17 and B cells in neuromyelitis optica spectrum disorder	51
Nigrostriatal tau pathology in parkinsonism and Parkinson’s disease	51
Human lesions and animal studies link the claustrum to perception, salience, sleep and pain	51
Basal forebrain integrity, cholinergic innervation and cognition in idiopathic Parkinson’s disease	50
Startle responses in Duchenne muscular dystrophy: a novel biomarker of brain dystrophin deficiency	50
Widespread white matter oedema in subacute COVID-19 patients with neurological symptoms	50
A passive and objective measure of recognition memory in Alzheimer’s disease using Fastball memory assessment	50
UNC13B and focal epilepsy	50
Failure of C9orf72 sense repeat-targeting antisense oligonucleotides: lessons learned and the path forward	49
The lysosomal β-glucocerebrosidase strikes mitochondria: implications for Parkinson’s therapeutics	49
Common and distinct fronto-striatal volumetric changes in heroin and cocaine use disorders	49
Recovery from aphasia in the first year after stroke	49
The human subthalamic nucleus transiently inhibits active attentional processes	49
Cdc42GAP deficiency contributes to the Alzheimer’s disease phenotype	49
Imaging chronic active lesions in multiple sclerosis: a consensus statement	48
Impaired value-based decision-making in Parkinson’s disease apathy	48
Neural basis of speech and grammar symptoms in non-fluent variant primary progressive aphasia spectrum	48
How patients with multiple sclerosis acquire disability	48
CGRP signalling in migraine: time to look downstream?	47
Effort avoidance as a core mechanism of apathy in frontotemporal dementia	47
Is it time to rename hereditary cases of cerebral palsy?	47
Characterizing proteomic and transcriptomic features of missense variants in amyotrophic lateral sclerosis genes	47
Motor compensation in Parkinson’s disease: an empirical challenge with clinical implications	47
Development of a novel tau propagation mouse model endogenously expressing 3 and 4 repeat tau isoforms	46
Correction to: Bidirectional gut-to-brain and brain-to-gut propagation of synucleinopathy in non-human primates	46
Cul-4 inhibition rescues spastin levels and reduces defects in hereditary spastic paraplegia models	46

Stimulation of frontal pathways disrupts hand muscle control during object manipulation	45
C-terminal TMEM106B fragments in human brain correlate with disease-associated TMEM106B haplotypes	45
Emotional bias modification weakens game-related compulsivity and reshapes frontostriatal pathways	45
Bridging the gaps between JCV infection models and human disease	45
ZSCAN10 deficiency causes a neurodevelopmental disorder with characteristic oto-facial malformations	45
Seeding, maturation and propagation of amyloid β-peptide aggregates in Alzheimer’s disease	45
The visual cortex in the blind but not the auditory cortex in the deaf becomes multiple-demand regions	44
Amyloid-β-activated microglia can induce compound proteinopathies	44
Tiam1 is part of a novel mechanism for morphine tolerance and hyperalgesia	44
Decomposing MRI phenotypic heterogeneity in epilepsy: a step towards personalized classification	44
Shedding light on a novel circuit within primary motor cortex as a target for neuromodulation	44
Four dimensions of naturalistic language production in aphasia after stroke	44
Biomarker evidence of neurodegeneration in mid-life former rugby players	44
Localizing epileptogenic tissues in epilepsy: are we losing (the) focus?	43
Morc2a variants cause hydroxyl radical-mediated neuropathy and are rescued by restoring GHKL ATPase	43
Smarter adaptive platform clinical trials in neurology	43
The basal forebrain cholinergic system as target for cell replacement therapy in Parkinson’s disease	43
Diffusely abnormal white matter converts to T2 lesion volume in the absence of MRI-detectable acute inflammation	43
PTPA variants and the risk for Parkinson’s disease in diverse ancestry populations	43
Alzheimer proteopathic tau seeds are biochemically a forme fruste of mature paired helical filaments	43
Thalamic stereo-EEG in epilepsy surgery: where do we stand?	42
The functional role of the precuneus	42
Cervical lymph nodes and ovarian teratomas as germinal centres in NMDA receptor-antibody encephalitis	42
The ageing central nervous system in multiple sclerosis: the imaging perspective	42
Broad activation of the Parkin pathway induces synaptic mitochondrial deficits in early tauopathy	42
Synaptic and cognitive impairment associated with L444P heterozygous glucocerebrosidase mutation	42
Motor network gamma oscillations in chronic home recordings predict dyskinesia in Parkinson’s disease	42
Brain accumulation of lactosylceramide characterizes GALC deficiency in a zebrafish model of Krabbe disease	42
Understanding brain calcification via N-terminal acetylation at the Golgi apparatus	42
Interpretable surface-based detection of focal cortical dysplasias: a Multi-centre Epilepsy Lesion Detection study	42
Anterior optic pathway pathology in CNS demyelinating diseases	41
Corrigendum to: Myopathic mitochondrial DNA depletion syndrome associated with biallelic variants in LIG3	41
Reply: An epigenetic basis for genetic anticipation in facioscapulohumeral muscular dystrophy type 1	41
Right temporal degeneration and socioemotional semantics: semantic behavioural variant frontotemporal dementia	41
Imbalanced basal ganglia connectivity is associated with motor deficits and apathy in Huntington’s disease	41
Reply: The challenge of assessing invasive biomarkers for epilepsy surgery and To plan efficacious epilepsy surgery	41
Resting-state EEG reveals four subphenotypes of amyotrophic lateral sclerosis	41
Interleukin-17B is a new biomarker of human muscle regeneration in dystrophinopathies	41
One transgene, two myopathies: an MTM1 ‘cross gene therapy’ for BIN1 deficiency?	41
TGFβ4 alleviates the phenotype of Charcot–Marie–Tooth disease type 1A	41
Direct electrical brain stimulation of human memory: lessons learnt and future perspectives	40
Reply: Methodological drawbacks in the alleged association between foetal sonographic anomalies and autism	40
Of networked lesions and lesioned networks	40
Reply: Neural substrates of the link between dual-task gait and dementia: an intermediary step in which direction?	40
Ockham’s razor, not a barber’s weapon but a writer’s tool	40
Poor statistical reporting in a spinal cord injury clinical trial	40
Plasma biomarkers in chronic single moderate/severe traumatic brain injury	40
Chasing MOG antibodies down … assays and lumbar punctures	40
Reply: Putative benefits of vitamin D supplements in multiple sclerosis out of reach due to sample size	40
Brainstem cavernous malformations: observation, microsurgical resection or stereotactic radiosurgery	39
Efficacy of MEDI0618, a pH-dependent monoclonal antibody targeting PAR2, in preclinical models of migraine	39
Clinicopathological correlates in the frontotemporal lobar degeneration–motor neuron disease spectrum	39
Myelination potential and injury susceptibility of grey versus white matter human oligodendrocytes	39
Genome-wide epistasis analysis reveals significant epistatic signals associated with Parkinson’s disease risk	39
Medial temporal lobe structural changes when Down syndrome and Alzheimer’s disease collide	39
Interaction of motor behaviour, cortical oscillations and deep brain stimulation in Parkinson’s disease	39
Uncovering the distinct macro-scale anatomy of dysexecutive and behavioural degenerative diseases	39
Nifuroxazide rescues the deleterious effects due to CHCHD10-associated MICOS defects in disease models	38
The Wernicke conundrum revisited: evidence from connectome-based lesion-symptom mapping	38
The importance of offering early genetic testing in everyone with amyotrophic lateral sclerosis	38
Predictors of functional outcomes in patients with facioscapulohumeral muscular dystrophy	38
Noradrenergic alterations in Parkinson’s disease: a combined 11C-yohimbine PET/neuromelanin MRI study	38
Motivational and cognitive predictors of apathy after subthalamic nucleus stimulation in Parkinson’s disease	38
An extended amygdala circuit at the core of long-term post-sepsis psychiatric disorders	38
Genome-wide contribution of common short-tandem repeats to Parkinson’s disease genetic risk	38
Mitochondrial dynamics and bioenergetics in Alzheimer’s induced pluripotent stem cell-derived neurons	38
Heterozygous PRKN mutations are common but do not increase the risk of Parkinson’s disease	38
Great science does not communicate itself: but who should and how?	38
Spreading depolarizations in ischaemia after subarachnoid haemorrhage, a diagnostic phase III study	38
Phenoconversion in pure autonomic failure: a multicentre prospective longitudinal cohort study	38
Neurophysiological consequences of synapse loss in progressive supranuclear palsy	37
Role of pattern recognition receptors in chemotherapy-induced neuropathic pain	37
Mitochondrial damage is associated with an early immune response in inclusion body myositis	37
Defining repetitive behaviours in frontotemporal dementia	37
Dopamine and deep brain stimulation accelerate the neural dynamics of volitional action in Parkinson's disease	37
Intra-putaminal muscarinic receptor agonist infusion induces a dystonic phenotype in non-human primate	37
Limitation of life sustaining therapy in disorders of consciousness: ethics and practice	37
Ligand-free mitochondria-localized mutant AR-induced cytotoxicity in spinal bulbar muscular atrophy	37
Multimodal layer modelling reveals in vivo pathology in amyotrophic lateral sclerosis	37
Cation leak through the ATP1A3 pump causes spasticity and intellectual disability	37
Neurovascular injury with complement activation and inflammation in COVID-19	36
Expedited epilepsy surgery prior to drug resistance in children: a frontier worth crossing?	36
Correction to: TMEM63C mutations cause mitochondrial morphology defects and underlie hereditary spastic paraplegia	36
Dynamic reorganization of task-related network interactions in post-stroke aphasia recovery	36
Seronegative autoimmune encephalitis: clinical characteristics and factors associated with outcomes	36
Functional connectivity drives stroke recovery: shifting the paradigm from correlation to causation	36
Analysing an allelic series of rare missense variants of CACNA1I in a Swedish schizophrenia cohort	36
Clinical features and prognostic factors in adults with viral meningitis	36
Increase of HCN current in SOD1-associated amyotrophic lateral sclerosis	36
CSF1R inhibition depletes brain macrophages and reduces brain virus burden in SIV-infected macaques	35
Prognostic value of single-subject grey matter networks in early multiple sclerosis	35
The risk of secondary progressive multiple sclerosis is geographically determined but modifiable	35
Who am I?	35
ILAE position on early surgery for drug sensitive lesional focal epilepsy	35
The emerging field of non-invasive brain stimulation in Alzheimer’s disease	35