OOIR: Observatory of International Research

Papers

(The H4-Index of Brain is 75. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Correction to: Variants in the SK2 channel gene (KCNN2) lead to dominant neurodevelopmental movement disorders	410
Reply: Is postural tachycardia syndrome a psychogenic disorder?; Notes on establishing fear conditioning as causal in the postural orthostatic tachycardia syndrome; Patients with POTS fear that data o	385
Methodological drawbacks in the alleged association between foetal sonographic anomalies and autism	376
‘Seeding’ the idea of early diagnostics in synucleinopathies	228
Trigeminal nerve microstructure is linked with neuroinflammation and brainstem activity in migraine	203
PET-MRI biomarkers reveal efficacy of a novel NLRP3 inhibitor in Parkinson’s disease models	201
Apathy, effort-based decisions and brain integrity in Alzheimer’s and Parkinson’s diseases	196
Choroid plexus mis-splicing and altered cerebrospinal fluid composition in myotonic dystrophy type 1	194
ActivatingRAC1variants in the switch II region cause a developmental syndrome and alter neuronal morphology	189
Associations between accelerated forgetting, amyloid deposition and brain atrophy in older adults	189
Genetically identical twin-pair difference models support the amyloid cascade hypothesis	185
In vivo self-assembled siRNAs ameliorate neurological pathology in TDP-43-associated neurodegenerative disease	185
We’re all in this together: a rejoinder to Masud Husain’s (rant) editorial	178
Clinical and genetic characterization of a progressive RBL2-associated neurodevelopmental disorder	171
Deep brain stimulation: a tale of two targets … and closing the loop	166
Peripherin is a biomarker of axonal damage in Guillain-Barré syndrome: a pathophysiological annotation	166
Optogenetic stimulation of the superior colliculus suppresses genetic absence seizures	149
The axon initial segment as a source of neuropathic pain	149
Dysregulated cortical excitability and tau phosphorylation in a β3 integrin mouse model of autism	148
Biallelic ADAM22 pathogenic variants cause progressive encephalopathy and infantile-onset refractory epilepsy	143
Lesion correlates of impaired acoustic-phonetic perception after unilateral left hemisphere stroke	141
De novo variants in ATXN7L3 lead to developmental delay, hypotonia and distinctive facial features	141
Mapping the peripheral immune landscape of Parkinson’s disease patients with single-cell sequencing	140
Dysfunction of the magnocellular subdivision of the visual thalamus in developmental dyslexia	137
Somatic variants of MAP3K3 are sufficient to cause cerebral and spinal cord cavernous malformations	136

The vascular contribution of apolipoprotein E to Alzheimer’s disease	136
Clinical and genetic spectrum of 355 Chinese children with epilepsy: a trio-sequencing-based study	125
Clinical dimensions along the non-fluent variant primary progressive aphasia spectrum	124
Global network and local vulnerabilities underlie brain atrophy across Parkinson’s disease stages	124
The use of optical coherence tomography in neurology: a review	117
The inferior fronto-occipital fasciculus: bridging phylogeny, ontogeny and functional anatomy	115
Cerebral amyloid angiopathy interacts with neuritic amyloid plaques to promote tau and cognitive decline	114
Thalamostriatal disconnection underpins long-term seizure freedom in frontal lobe epilepsy surgery	112
Distinct subcellular autophagy impairments in induced neurons from patients with Huntington's disease	109
Diffusion MRI tracks cortical microstructural changes during the early stages of Alzheimer’s disease	108
Source-sink connectivity: a novel interictal EEG marker for seizure localization	107
Speech and language markers of neurodegeneration: a call for global equity	105
3T MRI of rapid brain activity changes driven by subcallosal cingulate deep brain stimulation	103
A data-driven study of Alzheimer's disease related amyloid and tau pathology progression	101
Gain-of-function and loss-of-function variants in GRIA3 lead to distinct neurodevelopmental phenotypes	100
Brain cholesterol and Alzheimer's disease: challenges and opportunities in probe and drug development	99
Impaired ribosome-associated quality control of C9orf72 arginine-rich dipeptide-repeat proteins	99
‘Hippocampal innate inflammatory gliosis only’ in pharmacoresistant temporal lobe epilepsy	98
Brain repair mechanisms after cell therapy for stroke	96
From bugs to brain: unravelling the GABA signalling networks in the brain–gut–microbiome axis	93
Correction to: New genotype-phenotype correlations in a large European cohort of patients with sarcoglycanopathy	92
Loss of DOT1L disrupts neuronal transcription and leads to a neurodevelopmental disorder	91
Demystifying interictal discharges and seizure initiation in focal epilepsy	90
Molecular and clinical spectrum of epilepsy-dyskinesia syndromes: a cross-sectional study of 609 patients	90
Structural covariance analysis for neurodegenerative and neuroinflammatory brain disorders	89
The spectrum of disease and tau pathology of nodding syndrome in Uganda	89
Reply: Unblinding in the lecanemab trial in Alzheimer’s disease	89
Cortical cerebral microinfarcts spark cognitive decline	89
Evolutionary perspectives on mRNA signatures of neurodegeneration-related brain remodelling	88
Normalization of network activity in an epilepsy model with a constitutively active GABBR2 variant	88
Midbrain cytotoxic T cells as a distinct neuropathological feature of progressive supranuclear palsy	87
That which we call cortisol awakening response, by any other word would smell as sweet	86
The three deceits of bureaucracy	84
Extra-cranial cholinergic lesions in dementia with Lewy bodies	84
New mechanistic insights into hereditary spastic paraplegias	83
Treatment-resistant recurrent unipolar and bipolar depression: associative learning abnormalities	81
Disruption of DNA methylation underpins the neuroinflammation induced by targeted CNS radiotherapy	81
Biallelic LGI1 and ADAM23 variants cause hippocampal epileptic encephalopathy via the LGI1–ADAM22/23 pathway	81
Preclinical type 2 diabetes mellitus subtypes: new insights into diabetes, depression and dementia	81
How COVID-19 affects microvessels in the brain	80
Functional network reorganization precedes apathy in Parkinson’s disease: a neural marker of risk?	80
Activation and sensitization of meningeal nociceptors by PACAP-38: implications for migraine headache	79
Integrative genomics reveals pathogenic mediator of valproate-induced neurodevelopmental disability	79
Biallelic null variants in PNPLA8 cause microcephaly by reducing the number of basal radial glia	78
Integrative miRNA–mRNA profiling of human epidermis: unique signature of SCN9A painful neuropathy	78
The interictal suppression hypothesis is the dominant differentiator of seizure onset zones in focal epilepsy	78
Multiple sclerosis in Denmark (1950–2023): mean age, sex distribution, incidence and prevalence	77
Hippocampal synaptic failure is an early event in experimental parkinsonism with subtle cognitive deficit	77
Loss-of-function variants inMYCBP2cause neurobehavioural phenotypes and corpus callosum defects	76
Cross-seeding by prion protein inactivates TDP-43	76

Clinically relevant mitochondrial-targeted therapy improves chronic outcomes after traumatic brain injury