OOIR: Observatory of International Research

Papers

(The H4-Index of Brain is 74. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Correction to: Variants in the SK2 channel gene (KCNN2) lead to dominant neurodevelopmental movement disorders	399
Reply: Is postural tachycardia syndrome a psychogenic disorder?; Notes on establishing fear conditioning as causal in the postural orthostatic tachycardia syndrome; Patients with POTS fear that data o	374
Methodological drawbacks in the alleged association between foetal sonographic anomalies and autism	362
‘Seeding’ the idea of early diagnostics in synucleinopathies	215
Trigeminal nerve microstructure is linked with neuroinflammation and brainstem activity in migraine	196
PET-MRI biomarkers reveal efficacy of a novel NLRP3 inhibitor in Parkinson’s disease models	194
Apathy, effort-based decisions and brain integrity in Alzheimer’s and Parkinson’s diseases	192
Distinct subcellular autophagy impairments in induced neurons from patients with Huntington's disease	187
Clinical dimensions along the non-fluent variant primary progressive aphasia spectrum	183
Somatic variants of MAP3K3 are sufficient to cause cerebral and spinal cord cavernous malformations	183
The vascular contribution of apolipoprotein E to Alzheimer’s disease	182
Dysfunction of the magnocellular subdivision of the visual thalamus in developmental dyslexia	177
Associations between accelerated forgetting, amyloid deposition and brain atrophy in older adults	171
‘Hippocampal innate inflammatory gliosis only’ in pharmacoresistant temporal lobe epilepsy	162
Brain repair mechanisms after cell therapy for stroke	160
Gain-of-function and loss-of-function variants in GRIA3 lead to distinct neurodevelopmental phenotypes	159
Choroid plexus mis-splicing and altered cerebrospinal fluid composition in myotonic dystrophy type 1	146
Diffusion MRI tracks cortical microstructural changes during the early stages of Alzheimer’s disease	144
Genetically identical twin-pair difference models support the amyloid cascade hypothesis	140
Speech and language markers of neurodegeneration: a call for global equity	140
Source-sink connectivity: a novel interictal EEG marker for seizure localization	139
The inferior fronto-occipital fasciculus: bridging phylogeny, ontogeny and functional anatomy	136
In vivo self-assembled siRNAs ameliorate neurological pathology in TDP-43-associated neurodegenerative disease	136
Peripherin is a biomarker of axonal damage in Guillain-Barré syndrome: a pathophysiological annotation	131
We’re all in this together: a rejoinder to Masud Husain’s (rant) editorial	131

Impaired ribosome-associated quality control of C9orf72 arginine-rich dipeptide-repeat proteins	130
Clinical and genetic characterization of a progressive RBL2-associated neurodevelopmental disorder	122
Deep brain stimulation: a tale of two targets … and closing the loop	120
The axon initial segment as a source of neuropathic pain	118
Optogenetic stimulation of the superior colliculus suppresses genetic absence seizures	114
Dysregulated cortical excitability and tau phosphorylation in a β3 integrin mouse model of autism	111
Thalamostriatal disconnection underpins long-term seizure freedom in frontal lobe epilepsy surgery	108
Biallelic ADAM22 pathogenic variants cause progressive encephalopathy and infantile-onset refractory epilepsy	106
De novo variants in ATXN7L3 lead to developmental delay, hypotonia and distinctive facial features	105
Lesion correlates of impaired acoustic-phonetic perception after unilateral left hemisphere stroke	102
ActivatingRAC1variants in the switch II region cause a developmental syndrome and alter neuronal morphology	102
From bugs to brain: unravelling the GABA signalling networks in the brain–gut–microbiome axis	100
Clinical and genetic spectrum of 355 Chinese children with epilepsy: a trio-sequencing-based study	100
Mapping the peripheral immune landscape of Parkinson’s disease patients with single-cell sequencing	99
Brain cholesterol and Alzheimer's disease: challenges and opportunities in probe and drug development	97
Cerebral amyloid angiopathy interacts with neuritic amyloid plaques to promote tau and cognitive decline	94
3T MRI of rapid brain activity changes driven by subcallosal cingulate deep brain stimulation	94
A data-driven study of Alzheimer's disease related amyloid and tau pathology progression	94
The use of optical coherence tomography in neurology: a review	93
Correction to: New genotype-phenotype correlations in a large European cohort of patients with sarcoglycanopathy	93
Cytotoxic T cells and plasma cells dominate early in temporal lobe epilepsy with GAD antibodies	92
Loss of DOT1L disrupts neuronal transcription and leads to a neurodevelopmental disorder	90
Activation and sensitization of meningeal nociceptors by PACAP-38: implications for migraine headache	89
Molecular and clinical spectrum of epilepsy-dyskinesia syndromes: a cross-sectional study of 609 patients	89
Demystifying interictal discharges and seizure initiation in focal epilepsy	88
Hitching a ride on exosomes: a new approach for the delivery of siRNA-mediated therapies	88
That which we call cortisol awakening response, by any other word would smell as sweet	87
Reply: Unblinding in the lecanemab trial in Alzheimer’s disease	87
The three deceits of bureaucracy	86
Extra-cranial cholinergic lesions in dementia with Lewy bodies	85
New mechanistic insights into hereditary spastic paraplegias	84
Preclinical type 2 diabetes mellitus subtypes: new insights into diabetes, depression and dementia	83
Disruption of DNA methylation underpins the neuroinflammation induced by targeted CNS radiotherapy	81
Multiple sclerosis in Denmark (1950–2023): mean age, sex distribution, incidence and prevalence	80
Stuttering associated with a pathogenic variant in the chaperone protein cyclophilin 40	80
Defective lipid signalling caused by mutations inPIK3C2Bunderlies focal epilepsy	80
The spectrum of disease and tau pathology of nodding syndrome in Uganda	80
Evolutionary perspectives on mRNA signatures of neurodegeneration-related brain remodelling	79
Multiple lines of evidence for disruption of nuclear lamina and nucleoporins in FUS amyotrophic lateral sclerosis	79
Normalization of network activity in an epilepsy model with a constitutively active GABBR2 variant	79
Midbrain cytotoxic T cells as a distinct neuropathological feature of progressive supranuclear palsy	77
Synaptic dysregulation in a mouse model of GRIN2D developmental and epileptic encephalopathy	77
Biallelic LGI1 and ADAM23 variants cause hippocampal epileptic encephalopathy via the LGI1–ADAM22/23 pathway	76
Treatment-resistant recurrent unipolar and bipolar depression: associative learning abnormalities	75
Cortical cerebral microinfarcts spark cognitive decline	75
Clinically relevant mitochondrial-targeted therapy improves chronic outcomes after traumatic brain injury	74
How COVID-19 affects microvessels in the brain	74
Multifaceted nanoparticles: emerging mechanisms and therapies in neurodegenerative diseases	74
Functional network reorganization precedes apathy in Parkinson’s disease: a neural marker of risk?	74