Biotechnology and Bioengineering

Papers
(The TQCC of Biotechnology and Bioengineering is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)
ArticleCitations
Technology outlook for real‐time quality attribute and process parameter monitoring in biopharmaceutical development—A review88
Scale‐up economics for cultured meat82
Metabolic engineering of Pichia pastoris for malic acid production from methanol59
“High‐risk” host cell proteins (HCPs): A multi‐company collaborative view58
Current technologies to endotoxin detection and removal for biopharmaceutical purification58
The role of extracellular DNA in the formation, architecture, stability, and treatment of bacterial biofilms58
Advances in encapsulin nanocompartment biology and engineering53
Hybrid‐EKF: Hybrid model coupled with extended Kalman filter for real‐time monitoring and control of mammalian cell culture49
Biogenesis and mechanisms of microRNA‐mediated gene regulation49
Improving lysine production through construction of an Escherichia coli enzyme‐constrained model45
Consolidated bioprocessing performance of a two‐species microbial consortium for butanol production from lignocellulosic biomass44
A review of manufacturing capabilities of cell spheroid generation technologies and future development43
Microbial microdroplet culture system (MMC): An integrated platform for automated, high‐throughput microbial cultivation and adaptive evolution40
Moving from the bench towards a large scale, industrial platform process for adeno‐associated viral vector purification40
Novel nucleic acid detection strategies based on CRISPR‐Cas systems: From construction to application39
Overview on immobilization of enzymes on synthetic polymeric nanofibers fabricated by electrospinning39
A genome‐scale metabolic network model and machine learning predict amino acid concentrations in Chinese Hamster Ovary cell cultures38
Optimizing the biosynthesis of oxygenated and acetylated Taxol precursors in Saccharomyces cerevisiae using advanced bioprocessing strategies38
Ultrahigh‐cell‐density heterotrophic cultivation of the unicellular green alga Chlorella sorokiniana for biomass production37
Advances in mapping the epigenetic modifications of 5‐methylcytosine (5mC), N6‐methyladenine (6mA), and N4‐methylcytosine (4mC)37
Manufacturing a chimpanzee adenovirus‐vectored SARS‐CoV‐2 vaccine to meet global needs36
A common framework for integrated and continuous biomanufacturing36
A CRISPR‐Cas12a‐derived biosensor enabling portable personal glucose meter readout for quantitative detection of SARS‐CoV‐236
Metabolic engineering of E. coli for improving mevalonate production to promote NADPH regeneration and enhance acetyl‐CoA supply36
High‐level production of 3‐hydroxypropionic acid from glycerol as a sole carbon source using metabolically engineered Escherichia coli35
Rewiring central carbon metabolism for tyrosol and salidroside production in Saccharomyces cerevisiae32
Extraction, isolation, purification, derivatization, bioactivity, structure–activity relationship, and application of polysaccharides from White jellyfungus32
Modeling of photosynthesis and respiration rate for microalgae–bacteria consortia32
Pilot‐scale demonstration of an end‐to‐end integrated and continuous biomanufacturing process32
Three‐dimensional culture models to study drug resistance in breast cancer32
Tailoring bacterial cellulose structure through CRISPR interference‐mediated downregulation of galU in Komagataeibacter xylinus CGMCC 295531
Production of β‐carotene in Saccharomyces cerevisiae through altering yeast lipid metabolism31
End‐to‐end continuous bioprocessing: Impact on facility design, cost of goods, and cost of development for monoclonal antibodies30
Bioprocess development for scalable production of cultivated meat30
Production of trimeric SARS‐CoV‐2 spike protein by CHO cells for serological COVID‐19 testing29
Developing a base‐editing system to expand the carbon source utilization spectra of Shewanella oneidensis MR‐1 for enhanced pollutant degradation29
Chromosome‐scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome29
High‐level β‐carotene production from xylose by engineered Saccharomyces cerevisiae without overexpression of a truncated HMG1 (tHMG1)29
Beyond heuristics: CFD‐based novel multiparameter scale‐up for geometrically disparate bioreactors demonstrated at industrial 2kL–10kL scales29
The usage of composite nanomaterials in biomedical engineering applications28
Extension of cell membrane boosting squalene production in the engineered Escherichia coli28
Autofluorescence of blood and its application in biomedical and clinical research28
Transforming data to information: A parallel hybrid model for real‐time state estimation in lignocellulosic ethanol fermentation27
Combined evolutionary engineering and genetic manipulation improve low pH tolerance and butanol production in a synthetic microbial Clostridium community27
Miniaturized electrochemical biosensor based on whole‐cell for heavy metal ions detection in water27
Extracellular vesicles from organoids and 3D culture systems27
Machine learning and statistical analyses for extracting and characterizing “fingerprints” of antibody aggregation at container interfaces from flow microscopy images27
Flux redistribution of central carbon metabolism for efficient production of l‐tryptophan in Escherichia coli27
Effect of alginate matrix engineered to mimic the pancreatic microenvironment on encapsulated islet function27
Exploiting heterologous and endogenous CRISPR‐Cas systems for genome editing in the probiotic Clostridium butyricum27
Toward in silico CMC: An industrial collaborative approach to model‐based process development26
Human trabecular meshwork cell behavior is influenced by collagen scaffold pore architecture and glycosaminoglycan composition26
End‐to‐end collaboration to transform biopharmaceutical development and manufacturing26
Production and monitoring of biomass and fucoxanthin with brown microalgae under outdoor conditions25
Evaluating potential of tissue‐engineered cryogels and chondrocyte derived exosomes in articular cartilage repair25
A transfer learning approach for predictive modeling of bioprocesses using small data25
Scaffolds obtained from decellularized human extrahepatic bile ducts support organoids to establish functional biliary tissue in a dish25
3D bioprinting and microscale organization of vascularized tissue constructs using collagen‐based bioink25
Production of high‐quality SARS‐CoV‐2 antigens: Impact of bioprocess and storage on glycosylation, biophysical attributes, and ELISA serologic tests performance25
Amino acid supplementation for enhancing recombinant protein production in E. coli25
Online/at‐line measurement, analysis and control of product titer and critical product quality attributes (CQAs) during process development25
Functional expression of eukaryotic cytochrome P450s in yeast25
Simulated oxygen and glucose gradients as a prerequisite for predicting industrial scale performance a priori24
The transition of Rhodobacter sphaeroides into a microbial cell factory24
Dynamics of microbial competition, commensalism, and cooperation and its implications for coculture and microbiome engineering24
Integrated continuous biomanufacturing on pilot scale for acid‐sensitive monoclonal antibodies24
In vivo evaluation of bioprinted prevascularized bone tissue24
Outer membrane vesicles (OMVs) enabled bio‐applications: A critical review24
Plasticized poly(vinylalcohol) and poly(vinylpyrrolidone) based patches with tunable mechanical properties for cardiac tissue engineering applications24
Real‐time monitoring of quality attributes by in‐line Fourier transform infrared spectroscopic sensors at ultrafiltration and diafiltration of bioprocess24
Construction of ajmalicine and sanguinarine de novo biosynthetic pathways using stable integration sites in yeast24
Evaluating the effects of microparticle addition on mycelial morphology, natural yellow pigments productivity, and key genes regulation in submerged fermentation of Monascus purpureus23
Microbial fatty acid transport proteins and their biotechnological potential23
Process development and optimization of continuous capture with three‐column periodic counter‐current chromatography23
Microfluidics for microalgal biotechnology23
Kinetic and hybrid modeling for yeast astaxanthin production under uncertainty23
Dual cytoplasmic‐peroxisomal engineering for high‐yield production of sesquiterpene α‐humulene in Yarrowia lipolytica23
Directed evolution of unspecific peroxygenase in organic solvents22
Scalable, two‐stage, autoinduction of recombinant protein expression in E. coli utilizing phosphate depletion22
Combined genomic and transcriptomic analysis of the dibutyl phthalate metabolic pathway in Arthrobacter sp. ZJUTW22
Technoeconomic analysis of semicontinuous bioreactor production of biopharmaceuticals in transgenic rice cell suspension cultures22
Increased metal tolerance and bioaccumulation of zinc and cadmium in Chlamydomonas reinhardtii expressing a AtHMA4 C‐terminal domain protein22
Downregulation of T7 RNA polymerase transcription enhances pET‐based recombinant protein production in Escherichia coli BL21 (DE3) by suppressing autolysis22
Microparticles globally reprogram Streptomyces albus toward accelerated morphogenesis, streamlined carbon core metabolism, and enhanced production of the antituberculosis polyketide pamamycin22
A mass spectrometry‐based high‐throughput screening method for engineering fatty acid synthases with improved production of medium‐chain fatty acids22
Combining model structure identification and hybrid modelling for photo‐production process predictive simulation and optimisation22
Assessment of quality attributes for adeno‐associated viral vectors22
Cell‐free protein synthesis enables one‐pot cascade biotransformation in an aqueous‐organic biphasic system22
Mining of UDP‐glucosyltrfansferases in licorice for controllable glycosylation of pentacyclic triterpenoids21
A CRISPR/Cas9 eraser strategy for contamination‐free PCR end‐point detection21
Bacteriophage‐receptor binding proteins for multiplex detection of Staphylococcus and Enterococcus in blood21
Strain engineering for high‐level 5‐aminolevulinic acid production in Escherichia coli21
Benzoic acid production via cascade biotransformation and coupled fermentation‐biotransformation21
Semirational engineering of an aldo–keto reductase KmAKR for overcoming trade‐offs between catalytic activity and thermostability21
Enhancing plasmid transformation efficiency and enabling CRISPR‐Cas9/Cpf1‐based genome editing in Clostridium tyrobutyricum21
New horizons in developing cell lysis methods: A review21
Alveolar mimics with periodic strain and its effect on the cell layer formation21
3D printed human organoids: High throughput system for drug screening and testing in current COVID‐19 pandemic21
An “energy‐auxotroph” Escherichia coli provides an in vivo platform for assessing NADH regeneration systems20
Rapid and multiplex detection of nosocomial pathogens on a phage‐based magnetoresistive lab‐on‐chip platform20
Hydrocyclones as cell retention device for CHO perfusion processes in single‐use bioreactors20
Biologically rapid synthesized silver nanoparticles from aqueous Eucalyptus camaldulensis leaf extract: Effects on hyphal growth, hydrolytic enzymes, and biofilm formation in Candida albican20
Recent advances in computational methods for biosensor design20
Increasing cell‐free gene expression yields from linear templates in Escherichia coli and Vibrio natriegens extracts by using DNA‐binding proteins20
Reduced type‐A carbohydrate‐binding module interactions to cellulose I leads to improved endocellulase activity20
Transformation of lignocellulose to starch‐like carbohydrates by organic acid‐catalyzed pretreatment and biological detoxification20
Maximizing mRNA vaccine production with Bayesian optimization20
Transcriptome profiling of human pluripotent stem cell‐derived cerebellar organoids reveals faster commitment under dynamic conditions20
Metabolic engineering of oleaginous yeast Rhodotorula toruloides for overproduction of triacetic acid lactone20
Systematic assessment of process analytical technologies for biologics19
Molecular tools and applications of Euglena gracilis: From biorefineries to bioremediation19
Optimization of 1,2,4‐butanetriol production from xylose in Saccharomyces cerevisiae by metabolic engineering of NADH/NADPH balance19
Virus filtration: A review of current and future practices in bioprocessing19
A high‐throughput and machine learning resistance monitoring system to determine the point of resistance for Escherichia coli with tetracycline: Combining UV‐visible spectrophotometry with prin19
Development of a dynamic in vitro stretch model of the alveolar interface with aerosol delivery19
Spy chemistry‐enabled protein directional immobilization and protein purification19
Design and evaluation of a continuous semipartition bioreactor for in situ liquid‐liquid extractive fermentation19
Halophilic archaea and their potential to generate renewable fuels and chemicals19
Cyclic l‐lactide synthesis from lignocellulose biomass by biorefining with complete inhibitor removal and highly simultaneous sugars assimilation19
Vascularization of iNSC spheroid in a 3D spheroid‐on‐a‐chip platform enhances neural maturation19
Technological tools and strategies for culturing human gut microbiota in engineered in vitro models19
Recombinant protein production‐associated metabolic burden reflects anabolic constraints and reveals similarities to a carbon overfeeding response19
Virus harvesting in perfusion culture: Choosing the right type of hollow fiber membrane19
Leloir glycosyltransferases enabled to flow synthesis: Continuous production of the natural C‐glycoside nothofagin19
A new model to analyze the temperature effect on the microalgae performance at large scale raceway reactors19
Systematic identification of safe harbor regions in the CHO genome through a comprehensive epigenome analysis19
Stretch‐driven microfluidic chip for nucleic acid detection18
Engineered citrate synthase improves citramalic acid generation in Escherichia coli18
New technologies in developing recombinant‐attenuated bacteria for cancer therapy18
Improved two‐stage protein expression and purification via autoinduction of both autolysis and auto DNA/RNA hydrolysis conferred by phage lysozyme and DNA/RNA endonuclease18
Knowledge transfer across cell lines using hybrid Gaussian process models with entity embedding vectors18
Recent trends using natural polymeric nanofibers as supports for enzyme immobilization and catalysis18
Enhanced microbial corrosion of stainless steel by Acidithiobacillus ferrooxidans through the manipulation of substrate oxidation and overexpression of rus18
Development and application of a cultivation platform for mammalian suspension cell lines with single‐cell resolution18
Recent advances, challenges and metabolic engineering strategies in the biosynthesis of 3‐hydroxypropionic acid18
Extracellular vesicles facilitate large‐scale dynamic exchange of proteins and RNA among cultured Chinese hamster ovary and human cells18
A robust soft sensor to monitor 1,3‐propanediol fermentation process by Clostridium butyricum based on artificial neural network18
Scaffold‐free biofabrication of adipocyte structures with magnetic levitation18
Comparative investigation of fine bubble and macrobubble aeration on gas utility and biotransformation productivity18
Hydrogen peroxide‐producing electrochemical bandage controlled by a wearable potentiostat for treatment of wound infections18
Heterogeneous diffusion in aerobic granular sludge18
White paper on high‐throughput process development for integrated continuous biomanufacturing17
Indirect regulation of temperature in raceway reactors by optimal management of culture depth17
How to measure diffusion coefficients in biofilms: A critical analysis17
Improving an intensified and integrated continuous bioprocess platform for biologics manufacturing17
Enhancing biosynthesis of 2'‐Fucosyllactose in Escherichia coli through engineering lactose operon for lactose transport and α ‐1,2‐Fucosyltransferase for solubility17
Rapid RNase inhibitor production to enable low‐cost, on‐demand cell‐free protein synthesis biosensor use in human body fluids17
Metabolic engineering strategies for butanol production in Escherichia coli17
Process intensification for cytochrome P450 BM3‐catalyzed oxy‐functionalization of dodecanoic acid17
Dynamic flux balance analysis of biomass and lipid production by Antarctic thraustochytrid Oblongichytrium sp. RT2316‐1317
Pathway engineering of Escherichia coli for α‐ketoglutaric acid production17
Microdroplet enabled cultivation of single yeast cells correlates with bulk growth and reveals subpopulation phenomena17
An in situ collagen‐HA hydrogel system promotes survival and preserves the proangiogenic secretion of hiPSC‐derived vascular smooth muscle cells17
Enhancing tryptophan production by balancing precursors in Escherichia coli17
3D printing of self‐standing and vascular supportive multimaterial hydrogel structures for organ engineering17
A generalized machine‐learning aided method for targeted identification of industrial enzymes from metagenome: A xylanase temperature dependence case study17
A review of synthesis of esters with aromatic, emulsifying, and lubricant properties by biotransformation using lipases17
Universal law for diffusive mass transport through mycelial networks17
Comparison of UV‐ and Raman‐based monitoring of the Protein A load phase and evaluation of data fusion by PLS models and CNNs16
Engineering Clostridium cellulovorans for highly selective n‐butanol production from cellulose in consolidated bioprocessing16
An integrated continuous downstream process with real‐time control: A case study with periodic countercurrent chromatography and continuous virus inactivation16
Tailoring translational strength using Kozak sequence variants improves bispecific antibody assembly and reduces product‐related impurities in CHO cells16
Display of lead‐binding proteins on Escherichia coli surface for lead bioremediation16
Technical‐scale biophotovoltaics for long‐term photo‐current generation from Synechocystis sp. PCC680316
Linoleic acid inhibits Pseudomonas aeruginosa biofilm formation by activating diffusible signal factor‐mediated quorum sensing16
Control of surge tanks for continuous manufacturing of monoclonal antibodies16
Characterization of HIV‐1 virus‐like particles and determination of Gag stoichiometry for different production platforms16
Characterizing the effect of substrate stiffness on the extravasation potential of breast cancer cells using a 3D microfluidic model16
Scale‐up of an intensified bioprocess for the expansion of bovine adipose‐derived stem cells (bASCs) in stirred tank bioreactors16
Glycosylation as a tool for rational vaccine design16
Systems metabolic engineering of Bacillus subtilis for efficient biosynthesis of 5‐methyltetrahydrofolate16
Rapid cGMP manufacturing of COVID‐19 monoclonal antibody using stable CHO cell pools16
Hydrogel microfluidic‐based liver‐on‐a‐chip: Mimicking the mass transfer and structural features of liver16
Strategies for high‐concentration drug substance manufacturing to facilitate subcutaneous administration: A review16
Live reporting for hypoxia: Hypoxia sensor–modified mesenchymal stem cells as in vitro reporters16
A copper‐specific microbial fuel cell biosensor based on riboflavin biosynthesis of engineered Escherichia coli16
Biomimetic surface delivery of NGF and BDNF to enhance neurite outgrowth15
Rapid and low‐cost sampling for detection of airborne SARS‐CoV‐2 in dehumidifier condensate15
Synergising biomass growth kinetics and transport mechanisms to simulate light/dark cycle effects on photo‐production systems15
PAMAM G4.5 dendrimers for targeted delivery of ferulic acid and paclitaxel to overcome P‐glycoprotein‐mediated multidrug resistance15
Microparticles enhance the formation of seven major classes of natural products in native and metabolically engineered actinobacteria through accelerated morphological development15
Dynamic co‐culture metabolic models reveal the fermentation dynamics, metabolic capacities and interplays of cheese starter cultures15
Fluctuations in glucose availability prevent global proteome changes and physiological transition during prolonged chemostat cultivations of Saccharomyces cerevisiae15
Highly efficient production of diverse rare ginsenosides using combinatorial biotechnology15
Effects of benzyl viologen on increasing NADH availability, acetate assimilation, and butyric acid production by Clostridium tyrobutyricum15
IL‐10 lentivirus‐laden hydrogel tubes increase spinal progenitor survival and neuronal differentiation after spinal cord injury15
Quantification of the HIV‐1 virus‐like particle production process by super‐resolution imaging: From VLP budding to nanoparticle analysis15
Scalable, methanol‐free manufacturing of the SARS‐CoV‐2 receptor‐binding domain in engineered Komagataella phaffii15
Conferring thermotolerant phenotype to wild‐type Yarrowia lipolytica improves cell growth and erythritol production15
Miniature auto‐perfusion bioreactor system with spiral microfluidic cell retention device15
Introduction of glycine synthase enables uptake of exogenous formate and strongly impacts the metabolism in Clostridium pasteurianum15
In vitro vascularized tumor platform for modeling tumor‐vasculature interactions of inflammatory breast cancer15
S‐Nitroso‐N‐acetylpenicillamine impregnated endotracheal tubes for prevention of ventilator‐associated pneumonia15
Metabolically engineered Caldicellulosiruptor bescii as a platform for producing acetone and hydrogen from lignocellulose15
An integrated digital microfluidic bioreactor for fully automatic screening of microalgal growth and stress‐induced lipid accumulation15
Engineered pro‐peptide enhances the catalytic activity of keratinase to improve the conversion ability of feather waste15
A model‐driven approach towards rational microbial bioprocess optimization14
Multi‐information source Bayesian optimization of culture media for cellular agriculture14
Random epigenetic modulation of CHO cells by repeated knockdown of DNA methyltransferases increases population diversity and enables sorting of cells with higher production capacities14
Fungal lipases as biocatalysts: A promising platform in several industrial biotechnology applications14
An integrated biomimetic array chip for establishment of collagen‐based 3D primary human hepatocyte model for prediction of clinical drug‐induced liver injury14
Structure‐function analysis of two closely related cutinases from Thermobifida cellulosilytica14
Bioreactor production of rVSV‐based vectors in Vero cell suspension cultures14
Modeling apoptosis resistance in CHO cells with CRISPR‐mediated knockouts of Bak1, Bax, and Bok14
Increasing yield of in vitro transcription reaction with at‐line high pressure liquid chromatography monitoring14
Sortase A: A chemoenzymatic approach for the labeling of cell surfaces14
Dissolved oxygen concentration regulates human hepatic organoid formation from pluripotent stem cells in a fully controlled bioreactor14
Accelerating and de‐risking CMC development with transposon‐derived manufacturing cell lines14
Application of metabolic modeling for targeted optimization of high seeding density processes14
Genome‐scale modeling for Bacillus coagulans to understand the metabolic characteristics14
Engineered yeast for efficient de novo synthesis of 7‐dehydrocholesterol14
Antibody disulfide bond reduction and recovery during biopharmaceutical process development—A review14
Towards continuous mAb purification: Clearance of host cell proteins from CHO cell culture harvests via “flow‐through affinity chromatography” using peptide‐based adsorbents14
Long‐term biofouling formation mediated by extracellular proteins in Nannochloropsis gaditana microalga cultures at different medium N/P ratios14
The effects of flux on the clearance of minute virus of mice during constant flux virus filtration14
IR780 loaded gelatin‐PEG coated gold core silica shell nanorods for cancer‐targeted photothermal/photodynamic therapy14
Dispersion of sulfur creates a valuable new growth medium formulation that enables earlier sulfur oxidation in relation to iron oxidation in Acidithiobacillus ferrooxidans cultures14
Reducing phenotypic instabilities of a microbial population during continuous cultivation based on cell switching dynamics14
An effective computational‐screening strategy for simultaneously improving both catalytic activity and thermostability of α‐l‐rhamnosidase14
Macroscopic modeling of bioreactors for recombinant protein producingPichia pastorisin defined medium14
Biodegradable and biocompatible graphene‐based scaffolds for functional neural tissue engineering: A strategy approach using dental pulp stem cells and biomaterials14
Endogenous carbohydrate esterases of Clostridium thermocellum are identified and disrupted for enhanced isobutyl acetate production from cellulose14
The design basis for the integrated and continuous biomanufacturing framework13
SDF‐1α gene‐activated collagen scaffold drives functional differentiation of human Schwann cells for wound healing applications13
Optimizing recombineering in Corynebacterium glutamicum13
A scalable bubble‐free membrane aerator for biosurfactant production13
Aggregation‐induced integrated stress response rejuvenates culture‐expanded human mesenchymal stem cells13
Design, fabrication, and characterization of a multimodal reconfigurable bioreactor for bone tissue engineering13
On‐chip determination of tissue‐specific metastatic potential of breast cancer cells13
Quercetin and hydroxytyrosol as modulators of hepatic steatosis: A NAFLD‐on‐a‐chip study13
Assessing the influence of perfusion on cardiac microtissue maturation: A heart‐on‐chip platform embedding peristaltic pump capabilities13
A computational learning paradigm to targeted discovery of biocatalysts from metagenomic data: A case study of lipase identification13
Temperature and oxygen level determine N2O respiration activities of heterotrophic N2O‐reducing bacteria: Biokinetic study13
High‐ and low‐molecular‐weight chitosan act as adjuvants during single‐dose influenza A virus protein vaccination through distinct mechanisms13
Biocatalytic synthesis of dihydroxy fatty acids as lipid mediators from polyunsaturated fatty acids by double dioxygenation of the microbial 12S‐lipoxygenase13
Recent progress on small molecular temperature‐sensitive fluorescent probes13
Plant extract‐based synthesis of metallic nanomaterials, their applications, and safety concerns13
Nonviral siRNA delivery systems for pancreatic cancer therapy13
The importance and future of biochemical engineering13
Strengthening the CAR‐T cell therapeutic application using CRISPR/Cas9 technology13
Stratified microbial structure and activity within anode biofilm during electrochemically assisted brewery wastewater treatment13
Gram‐scale production of the sesquiterpene α‐humulene with Cupriavidus necator13
Protein‐inorganic calcium‐phosphate supraparticles as a robust platform for enzyme co‐immobilization13
Angiogenic and osteogenic effects of flavonoids in bone regeneration13
Resource allocation explains lactic acid production in mixed‐culture anaerobic fermentations13
In‐silico media optimization for continuous cultures using genome scale metabolic networks: The case of CHO‐K112
Tracing production instability in a clonally derived CHO cell line using single‐cell transcriptomics12
Carbohydrate‐binding domains facilitate efficient oligosaccharides synthesis by enhancing mutant catalytic domain transglycosylation activity12
Modeling and simulation‐based design of electroenzymatic batch processes catalyzed by unspecific peroxygenase from A. aegerita12
Rapid at‐line early cell death quantification using capacitance spectroscopy12
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