OOIR: Observatory of International Research

Papers

(The TQCC of Biotechnology and Bioengineering is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
	79
Optical discrimination of pathological red blood cells	74
	65
	65
Computational fluid dynamics based digital twins of fixed bed bioreactors validate scaling principles for recombinant adeno‐associated virus gene therapy manufacturing	60
Biotechnology and Bioengineering: Volume 122, Number 12, December 2025	58
Effects of biofilm heterogeneity on the apparent mechanical properties obtained by shear rheometry	56
Dynamic D‐Allose Monitoring Via a Toggle‐Programmed Microbial Fluorescent Biosensor	54
Constructing multi‐enzymatic cascade reactions for selective production of 6‐bromoindirubin from tryptophan in Escherichia coli	53
An engineered ultrahigh affinity bi‐paratopic uPAR targeting agent confers enhanced tumor targeting	46
Concentration‐dependent diffusion of unlabeled protein within an in vitro hyaluronic acid matrix	44
Heterologous Expression of Candida antarctica Lipase B in Aspergillus niger Using CRISPR/Cas9‐mediated Multi‐Gene Editing	41
Dual‐targeting multifunctional hyaluronic acid ligand‐capped gold nanorods with enhanced endo‐lysosomal escape ability for synergetic photodynamic–photothermal therapy of cancer	40
High‐throughput screening of optimal process conditions using model predictive control	40
Phenazine‐Based Synthetic Biology to Signal Between Cells and Electrodes	39
Dual‐Stage Cross‐Flow Filtration: Integrated Capture and Purification of Virus‐Like Particles	39
RSEA: A Web Server for Pathway Enrichment Analysis of Metabolic Reaction Sets	39
Double‐reporter‐guided targeted activation of the oxytetracycline silent gene cluster in Streptomyces rimosus M527	39
Engineering Plasmid‐Free Escherichia coli via Synergistic Metabolic Tuning and Fermentation Optimization for High‐Titer Salidroside Biosynthesis	38
Genetically Programmed Control of Overflow Metabolism	38
Recent Advances in Laccase‐Based Nanobiocatalysts for Sustainable Bioremediation Applications	37
Optimizing Pichia Pastoris Cell‐Free Protein Synthesis to Improve Economics	37
Repressing expression of difficult‐to‐express recombinant proteins during the selection process increases productivity of CHO stable pools	37
Harnessing metabolic plasticity in CHO cells for enhanced perfusion cultivation	36
pH Threshold Impacts Chalcopyrite Bioleaching Dynamics for the Extreme Thermoacidophile Sulfurisphaera ohwakuensis	35

Super7 passaging method to improve Chinese hamster ovary cell fed‐batch performance	35
Engineered Stable, Antibiotic‐Free, High‐Level Protein Expression in the Probiotic Chassis Escherichia coli Nissle 1917	35
Elucidating the Interplay Between Resin Media, Feed Constituents, and Process Conditions in AAV Affinity Column Fouling With Confocal Microscopy	35
Current Advances and Future Prospects of Bulk and Microfluidic‐Enabled Electroporation Systems	34
Comparative Analysis of Bioreactor Design and Scale‐Up for Cultivated Meat Using Monte Carlo‐Based Timescale Modeling	34
Iron in blood cells: Function, relation to disease, and potential for magnetic separation	33
Designing the MyoFusion Media: A Serum‐Free Medium Optimized for Bovine Satellite Cell Differentiation	33
Biotechnology and Bioengineering: Volume 122, Number 5, May 2025	33
Expression of filaments of the Geobacter extracellular cytochrome OmcS in Shewanella oneidensis	33
Concentration of clarified pool by single‐pass tangential flow filtration to improve productivity of protein A capture step: Impact of clarification strategies	32
Enhanced bioprocess control to advance the manufacture of mesenchymal stromal cell‐derived extracellular vesicles in stirred‐tank bioreactors	32
Application of gas diffusion electrodes in bioeconomy: An update	31
Application and progress of 3D tumor models in breast cancer	31
Physiological Response of Penicillium chrysogenum to Mimicked Local and Global Perturbations of Substrate and Dissolved Oxygen Gradients at Industrial‐Scale	31
	30
Transferrin Purification, Biophysical Characterization, and Lung Biodistribution in Sickle Cell Disease Mice	30
Optimization of physical microenvironment to maintain the quiescence of human induced pluripotent stem cell‐derived hepatic stellate cells	30
Biocatalytic role of cytochrome P450s to produce antibiotics: A review	30
Continuous polyhydroxybutyrate production from biogas in an innovative two‐stage bioreactor configuration	29
Machine learning approaches to root cause analysis, characterization, and monitoring of subvisible particles in monoclonal antibody formulations	29
Affinity Peptides With pH Sensitivity for the Enrichment of CD38 ⁺ Cells	29
A robust multinutrient kinetic model for enhanced lutein and biomass yields in mixotrophic microalgae cultivation: A step towards successful large‐scale productions	29
Development of generic metabolic Raman calibration models using solution titration in aqueous phase and data augmentation for in‐line cell culture analysis	29
Engineering Bienzymatic Cascade for Efficient Biosynthesis of Citronellal and Citronellol	28
Improved production of heme using metabolically engineered Escherichia coli	28
Characterization and designing of an SAM riboswitch to establish a high‐throughput screening platform for SAM overproduction in Saccharomyces cerevisiae	28
Mediated Electrochemical Probing and Machine Learning for Cysteine and Reduced Monoclonal Antibody Quantification	28
A New Modeling Approach for Predicting the Growth of Filamentous Algae in Outdoor Algae‐Based Wastewater Treatment Systems	27
Analyzing protein conjugation reactions for antibody‐drug conjugate synthesis using polarized excitation emission matrix spectroscopy	27
Engineering an Overflow‐Responsive Regulation System for Balancing Cellular Redox and Optimizing Microbial Production	27
Semiautomated design and soluble expression of a chimeric antigen TbpAB01 from Glaesserella parasuis	27
Increased Mevalonate Production Using Engineered Citrate Synthase and Phosphofructokinase Variants of Escherichia coli	26
Culture system for longitudinal monitoring of bone dynamics ex vivo	26
Microbial production of odd‐chain fatty acids	25
Bioprinted dermis with human adipose tissue‐derived microvascular fragments promotes wound healing	25
Enhancing cell‐based therapies with synthetic gene circuits responsive to molecular stimuli	25
Experimental evolution reveals an effective avenue for d‐lactic acid production from glucose‐xylose mixtures via enhanced Glk activity and a cAMP‐independent CRP mutation	25
Acoustic levitation as a tool for cell‐driven self‐organization of human cell spheroids during long‐term 3D culture	25
An Engineered Multicellular Bacterial Network for Simultaneously Answering Multiple Computational Decision Problems	25
Reviewing the process intensification landscape through the introduction of a novel, multitiered classification for downstream processing	25
Reinforcement learning based temperature control of a fermentation bioreactor for ethanol production	24
A Label‐Free Rapid Fluorescence Screening Approach for Identifying Cell‐Penetrating Peptides Using ANS as an Extrinsic Probe	24
Lactic acid bacteria as a tool for biovanillin production: A review	24
Multi‐cell‐line learning for the data‐driven construction of mechanistic metabolic models	24
Establishment of low‐cost production platforms of polyhydroxyalkanoate bioplastics from Halomonas cupida J9	24
On‐column capping of poly dT media‐tethered mRNA accomplishes high capping efficiency, enhanced mRNA recovery, and improved stability against RNase	24
Single Cell Protein Production From Ethanol: Model‐Based Bioreactor Operation at Industrial Scale	24
Fine and combinatorial regulation of key metabolic pathway for enhanced β‐alanine biosynthesis with non‐inducible Escherichia coli	24
Accelerating attribute‐focused process and product development through the development and deployment of autonomous process analytical technology platform system	24
Effect of protein fouling on filtrate flux and virus breakthrough behaviors during virus filtration process	24

Commitment of human mesenchymal stromal cells towards ACL fibroblast differentiation upon rAAV‐mediated FGF‐2 and TGF‐β overexpression using pNaSS‐grafted PCL films	24
Development of a novel purification method for AAV vectors using tangential flow filtration	23
Biotechnological production of polyphosphate from industrial wash water	23
	23
Investigation of Oxidative Damage Mechanism of Chlorella sorokiniana by Gas–Liquid Phase Plasma	23
Biotechnology and Bioengineering: Volume 122, Number 7, July 2025	23
Biotechnology and Bioengineering: Volume 123, Number 2, February 2026	23
Biotechnology and Bioengineering: Volume 121, Number 2, February 2024	23
Advancing Malic Acid Production of Aspergillus oryzae : Combined Process Optimization and Application of Various Substrates	22
Substrate and nutrient manipulation during continuous cultivation of extremophilic algae, Galdieria spp. RTK 37.1, substantially impacts biomass productivity and composition	22
Fabrication and in vitro evaluation of 3D printed porous silicate substituted calcium phosphate scaffolds for bone tissue engineering	22
Artificial induction of chromosome aneuploidy in CHO cells alters their function as host cells	22
Covalent organic frameworks (COFs) as carrier for improved drug delivery and biosensing applications	22
Elucidating the effects of microbubble pinch‐off dynamics on mammalian cell viability	22
Rapid spectrophotometric detection for optimized production of landomycins and characterization of their therapeutic potential	22
Characterization of Sterilizing‐Grade Membranes/Prefilters and Application to mRNA‐LNP Process Development	22
Techno‐Economic Analysis of Membrane‐Based Purification Platforms for AAV Vector Production	22
Structural variability, implementational irregularities in mathematical modelling of polyhydroxyalkanoates (PHAs) production—A state‐of‐the‐art review	22
Tissue‐Specific Differential Flux Analysis Reveals Metabolic Insights Into Pancreatic β‐Cell Dysfunction in Type 2 Diabetes	21
Enhancing real‐time cell culture monitoring: Automated Raman model optimization with Taguchi method	21
Protein Diffusion in Electroporation‐Based Biopsy: Quantifying Protein Transport From Human Skin for Skin Liquid Sampling With Electroporation	21
Increasing yield of in vitro transcription reaction with at‐line high pressure liquid chromatography monitoring	21
Engineered Bacterial Ligand From Streptococcus pneumoniae on Macroporous Resins for Selective Affinity Capture of Secretory IgA	21
Efficient biosynthesis of α‐aminoadipic acid via lysine catabolism in Escherichia coli	20
Oxygen Consumption in Filamentous Pellets of Aspergillus niger: Microelectrode Measurements and Modeling	20
Streamlined Clarification and Capture Process for Monoclonal Antibodies Using Fluidized Bed Centrifugation and Multi‐Column Chromatography With Membrane Adsorbers	20
Open‐Source Anaerobic Digestion Modeling Platform, Anaerobic Digestion Model No. 1 Fast (ADM1F)	20
Evaluating Isochoric Freezing as a Strategy for Storage of Red Blood Cells	20
Metal cofactor regulation combined with rational genetic engineering of Schizochytrium sp. for high‐yield production of squalene	20
Bringing a scalable adaptive hybrid modeling framework closer to industrial use: Application on a multiscale fungal fermentation	20
PCR‐ and wash‐free detection of serum miRNA via signaling probe hybridization	20
Recent Research on Chondrocyte Dedifferentiation and Insights for Regenerative Medicine	20
Dynamic optimization of an integrated cultivation‐aggregation model for mAb production	20
Enhanced harvest performance predictability through advanced multivariate data analysis of mammalian cell culture particle size distribution	20
Bead to Bead Transfer, an Efficient Strategy to Scale‐up the Mesenchymal Stromal Cells‐Derived Secretome Bioproduction	20
Machine Learning Models of Phase Contrast Images Predict Efficiency of Human Pluripotent Stem Cell Differentiation to Cardiomyocytes	20
Cover Image, Volume 121, Number 8, August 2024	19
Continuous monitoring of IgG using immobilized fluorescent reporters	19
One‐Pot Hetero‐Di‐ C ‐Glycosylation of the Natural Polyphenol Phloretin by a Single C ‐Glycosyltransferase	19
Platform development for high‐throughput optimization of perfusion processes: Part I: Implementation of cell bleeds in microwell plates	19
Engineering Escherichia coli asymmetry distribution‐based synthetic consortium for shikimate production	19
Engineering Yarrowia lipolytica for Efficient Production of Erythritol by Decoding and Harnessing Osmotic‐Stress‐Responsive Genetic Targets	19
Biotechnology and Bioengineering: Volume 122, Number 9, September 2025	19
Plant Cell Organoids of Catharanthus roseus : A Novel Biotechnological Platform for Vinblastine and Indole‐Derived Alkaloids	19
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Corrigendum to “High‐Throughput Investigation of Endothelial‐to‐Mesenchymal Transformation (EndMT) With Combinatorial Cellular Microarrays”	18
Automated calibration and in‐line measurement of product quality during therapeutic monoclonal antibody purification using Raman spectroscopy	18
Real‐Time Auto Controlling of Viable Cell Density in Perfusion Cultivation Aided by In‐Line Dielectric Spectroscopy With Segmented Adaptive PLS Model	18
A Paradigm of Computer Vision and Deep Learning Empowers the Strain Screening and Bioprocess Detection	18
Establishment of a Single‐Cell Minimal Medium: A Case Study for Microfluidic Cultivation of Corynebacterium glutamicum	18
Engineering dense tumor constructs via cellular contraction of extracellular matrix hydrogels	18
Resistive Method for Bacterial Detection Employing a Silicon Nanowire Electrical Chip	18
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Deep hybrid modeling of a HEK293 process: Combining long short‐term memory networks with first principles equations	18
On the Prediction of pDNA Productivity Across Diverse Bioprocesses Using Ensemble Hybrid Models	18
Impact of Hormone on Growth and GA ₃ Regulation of Anthocyanin Biosynthesis in Suspension‐Culture Cells of Cyclocarya paliurus	18
Removal of Empty AAV Capsids to Undetectable Levels Using Orthogonal Purification Steps	18
Model‐based control system design to manage process parameters in mammalian cell culture for biopharmaceutical manufacturing	18
Fungal assisted bio‐treatment of environmental pollutants with comprehensive emphasis on noxious heavy metals: Recent updates	18
H₂O₂ feeding enables LPMO‐assisted cellulose saccharification during simultaneous fermentative production of lactic acid	18
Biointerface engineering through amalgamation of gene technology and site‐specific growth factor conjugation for efficient osteodifferentiation	17
Biotechnology and Bioengineering: Volume 120, Number 5, May 2023	17
Effects of Air Temperature on Transient Expression of Influenza Hemagglutinin in Nicotiana benthamiana : Analysis of Transgene Transcription and Plant St	17
Development of Raman Spectroscopy and Machine Learning Methods for Protein Aggregate Quantification: Application to BSA in Chromatographic Processes	17
Optimized Biosynthetic Pathway for Nonnatural Amino Acids: An Efficient Approach for L‐2‐Aminobutyric Acid Production	17
Engineering a Perfusion Bioreactor System for hiPSC‐Derived Progenitor Co‐Culture Capturing Microglial Features in CNS Development	17
Biotechnology and Bioengineering: Volume 121, Number 11, November 2024	17
Design space determination to optimize DNA complexation and full capsid formation in transient rAAV manufacturing	17
Higher efficiency of vanadate iron in heterogeneous Fenton‐like systems to pretreat sugarcane bagasse and its enzymatic saccharification	17
Biotechnology and Bioengineering: Volume 120, Number 10, October 2023	17
Cast‐Molded Channelized Hydrogel Scaffolds With Stereolithography‐Printed Templates	17
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Structure‐Guided Engineering of Alcohol Dehydrogenase for the Stereodivergent Synthesis of Amino Alcohols via Desymmetrization of Cyclic Diketones	17
Cover Image, Volume 121, Number 2, February 2024	17
Advanced cell technologies: Making protein, cell, and gene therapies a reality	17
Efficient and precise control of gene expression in Geobacter sulfurreducens through new genetic elements and tools for pollutant conversion	17
A computational model for single cell Lamin‐A structural organization after microfluidic compression	17
Modeling large‐scale bioreactors with diffusion equations. Part II: Characterizing substrate, oxygen, temperature, carbon dioxide, and pH profiles	17
Systems engineering Escherichia coli for efficient production p‐coumaric acid from glucose	17
Mesenchymal Stem Cells‐Derived Small Extracellular Vesicles and Their Validation as a Promising Treatment for Chondrosarcoma in a 3D Model in Vitro	16

Engineering an Escherichia coli based in vivo mRNA manufacturing platform	16
Construction of a CRISPR‐Cas9‐Based Genetic Editing Tool for Serratia marcescens Using a Stationary Phase Promoter and Its Application in Putrescine Prod	16
Physiological metabolic topology analysis of Halomonas elongata DSM 2581^T in response to sodium chloride stress	16
Role of carbon nanotubes (CNTs) in transgenic plant development	16
Manipulation of mRNA translation elongation influences the fragmentation of a biotherapeutic Fc‐fusion protein produced in CHO cells	16
Harnessing Cellular Feeling: Epigenetic to Mechanical Memory as a Framework for Stem Cell Manufacturing	16
One Plasmid Is All You Need: Genome Editing in Escherichia coli Using Endogenous TnpB and Endogenous Recombination System	16
Engineering Murine Cross‐Reactivity Into an Affibody to Human Death Receptor 5	16
Interpretable‐AI‐Based Model Structural Transfer Learning to Accelerate Bioprocess Model Construction	16
An adaptive soft‐sensor for advanced real‐time monitoring of an antibody‐drug conjugation reaction	16
Enzyme‐functionalized alginate microparticles enable anaerobic culture under ambient oxygen	16
Genome‐scale metabolic modeling of Thraustochytrium sp. RT2316‐16: Effects of nutrients on metabolism	16
Less Is More: Practical Insights Into Multivariate Regression Models for Raman Spectroscopy in Bioprocess Monitoring	16
Identification of yttrium oxide‐specific peptides for future recycling of rare earth elements from electronic scrap	16
Design an Energy‐Conserving Pathway for Efficient Biosynthesis of 1,5‐Pentanediol and 5‐Amino‐1‐Pentanol	16
Back Cover Image, Volume 120, Number 4, April 2023	15
Hierarchical dynamic regulation of Saccharomyces cerevisiae for enhanced lutein biosynthesis	15
Perfusion Process Intensification for Lentivirus Production Using a Novel Scale‐Down Model	15
Fibrin gel enhanced trilayer structure in cell‐cultured constructs	15
Sensitivity analysis and adaptive mutation strategy differential evolution algorithm for optimizing enzymes' turnover numbers in metabolic models	15
Scalable manufacturing platform for the production of PEGylated heme albumin	15
Transfer learning Bayesian optimization for competitor DNA molecule design for use in diagnostic assays	15
Meso‐ and thermophilic posttreatment of press water coming from a thermophilic municipal solid waste digester	15
In Situ Microscopy for Real‐Time Visualization of Microcarrier Cell Cultures for Live Virus Vaccine Process Development	15
N₂‐fixation can sustain wastewater treatment performance of photogranules under nitrogen‐limiting conditions	15
Designer probiotics: Opening the new horizon in diagnosis and prevention of human diseases	15
A New Aerosol‐Based Photobioreactor for the Cultivation of Cyanobacteria on Luffa	15
A multiscale modeling method for therapeutic antibodies in ion exchange chromatography	15
CFD‐based bioreactor model with proportional–integral–derivative controller functionality for dissolved oxygen and pH	14
Bacterial Laccase: Recent Advances in Production, Engineering Strategies, and Diagnostic Applications	14
Succinic Acid Production by Engineered Mannheimia succiniciproducens and Its Use in Chemoenzymatic Poly(Butylene Succinate) Synthesis	14
Bayesian Optimization in Bioprocess Engineering—Where Do We Stand Today?	14
Inside Front Cover Image, Volume 122, Number 8, August 2025	14
Controlling Enantioselectivity of Halohydrin Dehalogenase for Asymmetric Synthesis of Chiral Epichlorohydrin	14
Thermodynamic Evaluation of Dual Substrate Growth	14
Adjustment of the main biosynthesis modules to enhance the production of l‐homoserine in Escherichia coli W3110	14
Assessment of Anticancer Effects of Aloe vera on 3D Liver Tumor Spheroids in a Microfluidic Platform	14
Quorum sensing unveils the sludge floccule‐assisted stabilization of aerobic granules in granule‐dominated sequencing batch reactors	14
Modular RNAi Pathway Engineering Enhances Plasmid Copy Number Control in Yeast Bioproduction System	14
A Modular Mechanistic In Silico Model for In Vitro Transcription Process Yield and Product Quality Prediction	14
Design Space Assessment of Virus Inactivation in Plasma‐Derived Matrices Establishes a Single Detergent Alternative to TX‐100‐Containing Mixes	14
Reducing Structural Nonidentifiabilities in Upstream Bioprocess Models Using Profile‐Likelihood	14
Exploring the potential of CRISPR/Cas genome editing for vegetable crop improvement: An overview of challenges and approaches	14
Recent advances in biomedical applications of carbon and graphene quantum dots: A review	14
Constraint‐Based Metabolic Modeling of Synechococcus elongatus PCC 11801 and PCC 11802 for Photosynthetic Biomanufacturing	14
Enhancing CHO cell productivity through a dual selection system using Aspg and Gs in glutamine free medium	13
Development of growth selection system and pocket engineering of d‐amino acid oxidase to enhance selective deamination activity toward d‐phosphinothricin	13
Modeling the Performance of an Anaerobic Moving Bed Biofilm Reactor	13
2,6‐diaminopurine (Z)‐containing toehold probes improve genotyping sensitivity	13
Coevolving stability and activity of LsCR by a single point mutation and constructing neat substrate bioreaction system	13
Biotechnology and Bioengineering: Volume 120, Number 4, April 2023	13
The Missing Link: Connecting Cultivation Conditions and Refolding Performance via Inclusion Body Biophysical Properties	13
Fabrication of oxygen‐carrying microparticles functionalized with liver ECM‐proteins to improve phenotypic three‐dimensional in vitro liver assembly, function, and responses	13
Detergent Virus Inactivation in Chromatography Systems	13
Systematic review: External carbon source for biological denitrification for wastewater	13
Design and development of opto‐electrochemical biosensing devices for diagnosing chronic kidney disease	13
Early dynamic changes in iPSC oxygen consumption rate predict future cardiomyocyte differentiation	13
Psilocybin Production With Genetically Modified Aspergillus nidulans Under Pressurized Conditions	13
Biotechnology and Bioengineering: Volume 122, Number 1, January 2025	13
Real‐Time Monitoring of In Vitro Transcription for Production of mRNA Using Raman Spectroscopy	13
Robust platform for inline Raman monitoring and control of perfusion cell culture	13
Real‐time monitoring of biomass during Escherichia coli high‐cell‐density cultivations by in‐line photon density wave spectroscopy	13
Insights into product and process related challenges of lentiviral vector bioprocessing	13
Enhanced acetate utilization for value‐added chemicals production in Yarrowia lipolytica by integration of metabolic engineering and microbial electrosynthesis	13
Multiplexed Metabolic and Protein Engineering for D‐Limonene Overproduction in Saccharomyces cerevisiae	13
Cover Image, Volume 120, Number 3, March 2023	13
Impact of dual‐baculovirus infection on the Sf9 insect cell transcriptome during rAAV production using single‐cell RNA‐seq	13
Modeling Analysis of Oxygen Transfer Efficiency in Rest Cell Catalysis for Extra High‐Titer Xylonic Acid Bioproduction	13
Protein fouling during constant‐flux virus filtration: Mechanisms and modeling	12
Directed Evolution of an (R)‐Selective Transaminase Toward Higher Efficiency of Sitagliptin Analog Biosynthesis	12
LLM‐Guided Parameter Optimization for Mechanistic CHO Cell Bioreactor Models	12
Revisiting the Carbon Footprint of Single‐Use Technologies in Biomanufacturing: A Bottom‐Up Analysis Reveals a Paradigm Shift	12
Combining descriptive and predictive modeling to systematically design depth filtration‐based harvest processes for biologics	12
Computational framework to understand the clinical stages of COVID‐19 and visualization of time course for various treatment strategies	12
A fluidized‐bed‐riser adsorption system for continuous bioproduct recovery from crude feedstock	12
Enrichment of adeno‐associated virus serotype 5 full capsids by anion exchange chromatography with dual salt elution gradients	12
Modeling Multiscale Architecture of Biofilm Extracellular Matrix and Its Role in Oxygen Transport	12
Transcriptional biomarker discovery toward building a load stress reporting system for engineered Escherichia coli strains	12
Effectively Guiding Cell Elongation and Alignment by Constructing Micro/Nano Hierarchical Patterned Titania on Titanium Substrate	12
	12
Predictive scaling of fiber‐based protein A capture chromatography using mechanistic modeling	12
Challenges and opportunities in downstream separation processes for mesenchymal stromal cells cultured in microcarrier‐based stirred suspension bioreactors	12
Unsupervised Machine Learning‐Based Process Analytical Tools for Near Real‐Time Cell Morphology Analysis During CAR‐T Cell Manufacturing	12
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Proteo‐Transcriptomic Analysis Reveals the Mechanisms Underlying Escherichia coli Phenotypic Shifts Under Blue Light	12
Physics‐informed neural networks for biopharmaceutical cultivation processes: Consideration of varying process parameter settings	12
Multi‐lipase gene knockdown in Chinese hamster ovary cells using artificial microRNAs to reduce host cell protein mediated polysorbate degradation	11
Artificial Intelligence‐Powered Algal Biodiesel: The Future of Biofuel Production Through Data‐Driven Biotechnology	11
Balancing Doses of EL222 and Light Improves Optogenetic Induction of Protein Production in Komagataella phaffii	11
Sensors and chemometrics in downstream processing	11
Engineering of CoA‐Acylating Butyraldehyde Dehydrogenase for Enhanced 1,3‐Butanediol Production in Escherichia coli	11
Plasmid‐Free CRISPR/Cpf1 Genome Editing With In Vivo T7 RNA Polymerase‐Transcribed CRISPR RNA From Short Double‐Stranded DNA	11
Leveraging yeast sequestration to study and engineer posttranslational modification enzymes	11
Engineering of the Lrp/AsnC‐type transcriptional regulator DecR as a genetically encoded biosensor for multilevel optimization of L‐cysteine biosynthesis pathway in Escherichia coli	11
Modeling large‐scale bioreactors with diffusion equations. Part I: Predicting axial dispersion coefficient and mixing times	11