OOIR: Observatory of International Research

Papers

(The TQCC of Biotechnology and Bioengineering is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Concentration of clarified pool by single‐pass tangential flow filtration to improve productivity of protein A capture step: Impact of clarification strategies	67
Biotechnology and Bioengineering: Volume 122, Number 5, May 2025	66
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Optical discrimination of pathological red blood cells	57
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Continuous low pH viral inactivation: Operation and scaling strategy informs viral clearance study	53
Computational fluid dynamics based digital twins of fixed bed bioreactors validate scaling principles for recombinant adeno‐associated virus gene therapy manufacturing	52
Elucidating the Interplay Between Resin Media, Feed Constituents, and Process Conditions in AAV Affinity Column Fouling With Confocal Microscopy	51
Biotechnology and Bioengineering: Volume 122, Number 12, December 2025	48
Application and progress of 3D tumor models in breast cancer	47
Effects of biofilm heterogeneity on the apparent mechanical properties obtained by shear rheometry	43
Current Advances and Future Prospects of Bulk and Microfluidic‐Enabled Electroporation Systems	43
Genetically Programmed Control of Overflow Metabolism	43
Dynamic D‐Allose Monitoring Via a Toggle‐Programmed Microbial Fluorescent Biosensor	42
An engineered ultrahigh affinity bi‐paratopic uPAR targeting agent confers enhanced tumor targeting	41
Constructing multi‐enzymatic cascade reactions for selective production of 6‐bromoindirubin from tryptophan in Escherichia coli	41
RSEA: A Web Server for Pathway Enrichment Analysis of Metabolic Reaction Sets	39
Engineering Plasmid‐Free Escherichia coli via Synergistic Metabolic Tuning and Fermentation Optimization for High‐Titer Salidroside Biosynthesis	39
Concentration‐dependent diffusion of unlabeled protein within an in vitro hyaluronic acid matrix	38
Dual‐targeting multifunctional hyaluronic acid ligand‐capped gold nanorods with enhanced endo‐lysosomal escape ability for synergetic photodynamic–photothermal therapy of cancer	35
Harnessing metabolic plasticity in CHO cells for enhanced perfusion cultivation	35
Engineered Stable, Antibiotic‐Free, High‐Level Protein Expression in the Probiotic Chassis Escherichia coli Nissle 1917	34
High‐throughput screening of optimal process conditions using model predictive control	34
Double‐reporter‐guided targeted activation of the oxytetracycline silent gene cluster in Streptomyces rimosus M527	34

Application of gas diffusion electrodes in bioeconomy: An update	33
Optimizing Pichia Pastoris Cell‐Free Protein Synthesis to Improve Economics	33
Dual‐Stage Cross‐Flow Filtration: Integrated Capture and Purification of Virus‐Like Particles	33
Iron in blood cells: Function, relation to disease, and potential for magnetic separation	33
Repressing expression of difficult‐to‐express recombinant proteins during the selection process increases productivity of CHO stable pools	33
Expression of filaments of the Geobacter extracellular cytochrome OmcS in Shewanella oneidensis	33
Phenazine‐Based Synthetic Biology to Signal Between Cells and Electrodes	32
Super7 passaging method to improve Chinese hamster ovary cell fed‐batch performance	32
Enhanced bioprocess control to advance the manufacture of mesenchymal stromal cell‐derived extracellular vesicles in stirred‐tank bioreactors	32
Heterologous Expression of Candida antarctica Lipase B in Aspergillus niger Using CRISPR/Cas9‐mediated Multi‐Gene Editing	31
From spores to fungal pellets: A new high‐throughput image analysis highlights the structural development of Aspergillus niger	31
Physiological Response of Penicillium chrysogenum to Mimicked Local and Global Perturbations of Substrate and Dissolved Oxygen Gradients at Industrial‐Scale	31
Reinforcement learning based temperature control of a fermentation bioreactor for ethanol production	31
pH Threshold Impacts Chalcopyrite Bioleaching Dynamics for the Extreme Thermoacidophile Sulfurisphaera ohwakuensis	31
Engineering Bienzymatic Cascade for Efficient Biosynthesis of Citronellal and Citronellol	31
Improved production of heme using metabolically engineered Escherichia coli	30
Acoustic levitation as a tool for cell‐driven self‐organization of human cell spheroids during long‐term 3D culture	30
Optimization of physical microenvironment to maintain the quiescence of human induced pluripotent stem cell‐derived hepatic stellate cells	29
Bioprinted dermis with human adipose tissue‐derived microvascular fragments promotes wound healing	29
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Increased Mevalonate Production Using Engineered Citrate Synthase and Phosphofructokinase Variants of Escherichia coli	29
Accelerating attribute‐focused process and product development through the development and deployment of autonomous process analytical technology platform system	29
Semiautomated design and soluble expression of a chimeric antigen TbpAB01 from Glaesserella parasuis	28
A New Modeling Approach for Predicting the Growth of Filamentous Algae in Outdoor Algae‐Based Wastewater Treatment Systems	28
Characterization and designing of an SAM riboswitch to establish a high‐throughput screening platform for SAM overproduction in Saccharomyces cerevisiae	28
Experimental evolution reveals an effective avenue for d‐lactic acid production from glucose‐xylose mixtures via enhanced Glk activity and a cAMP‐independent CRP mutation	27
Enhancing cell‐based therapies with synthetic gene circuits responsive to molecular stimuli	27
A robust multinutrient kinetic model for enhanced lutein and biomass yields in mixotrophic microalgae cultivation: A step towards successful large‐scale productions	27
Affinity Peptides With pH Sensitivity for the Enrichment of CD38 ⁺ Cells	27
Culture system for longitudinal monitoring of bone dynamics ex vivo	27
Continuous polyhydroxybutyrate production from biogas in an innovative two‐stage bioreactor configuration	26
Reviewing the process intensification landscape through the introduction of a novel, multitiered classification for downstream processing	26
Machine learning approaches to root cause analysis, characterization, and monitoring of subvisible particles in monoclonal antibody formulations	26
Biocatalytic role of cytochrome P450s to produce antibiotics: A review	25
Transferrin Purification, Biophysical Characterization, and Lung Biodistribution in Sickle Cell Disease Mice	24
Microbial production of odd‐chain fatty acids	24
Bringing a scalable adaptive hybrid modeling framework closer to industrial use: Application on a multiscale fungal fermentation	24
Development of generic metabolic Raman calibration models using solution titration in aqueous phase and data augmentation for in‐line cell culture analysis	24
Mediated Electrochemical Probing and Machine Learning for Cysteine and Reduced Monoclonal Antibody Quantification	24
Fine and combinatorial regulation of key metabolic pathway for enhanced β‐alanine biosynthesis with non‐inducible Escherichia coli	24
Establishment of low‐cost production platforms of polyhydroxyalkanoate bioplastics from Halomonas cupida J9	24
Engineering an Overflow‐Responsive Regulation System for Balancing Cellular Redox and Optimizing Microbial Production	24
Analyzing protein conjugation reactions for antibody‐drug conjugate synthesis using polarized excitation emission matrix spectroscopy	24
Investigation of Oxidative Damage Mechanism of Chlorella sorokiniana by Gas–Liquid Phase Plasma	24
Biotechnological production of polyphosphate from industrial wash water	23
Bead to Bead Transfer, an Efficient Strategy to Scale‐up the Mesenchymal Stromal Cells‐Derived Secretome Bioproduction	23
Biotechnology and Bioengineering: Volume 123, Number 2, February 2026	23
Marine biological macromolecules as matrix material for biosensor fabrication	23
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Metal cofactor regulation combined with rational genetic engineering of Schizochytrium sp. for high‐yield production of squalene	22

Biotechnology and Bioengineering: Volume 122, Number 7, July 2025	22
Fabrication and in vitro evaluation of 3D printed porous silicate substituted calcium phosphate scaffolds for bone tissue engineering	22
Tissue‐Specific Differential Flux Analysis Reveals Metabolic Insights Into Pancreatic β‐Cell Dysfunction in Type 2 Diabetes	22
Dynamic optimization of an integrated cultivation‐aggregation model for mAb production	22
Influence of circadian rhythm on drug metabolism in 3D hepatic spheroids	22
Commitment of human mesenchymal stromal cells towards ACL fibroblast differentiation upon rAAV‐mediated FGF‐2 and TGF‐β overexpression using pNaSS‐grafted PCL films	22
Rapid spectrophotometric detection for optimized production of landomycins and characterization of their therapeutic potential	22
Artificial induction of chromosome aneuploidy in CHO cells alters their function as host cells	22
PCR‐ and wash‐free detection of serum miRNA via signaling probe hybridization	22
Biotechnology and Bioengineering: Volume 121, Number 2, February 2024	22
Structural variability, implementational irregularities in mathematical modelling of polyhydroxyalkanoates (PHAs) production—A state‐of‐the‐art review	22
Efficient biosynthesis of α‐aminoadipic acid via lysine catabolism in Escherichia coli	22
Evaluating Isochoric Freezing as a Strategy for Storage of Red Blood Cells	22
Enhancing real‐time cell culture monitoring: Automated Raman model optimization with Taguchi method	21
On‐column capping of poly dT media‐tethered mRNA accomplishes high capping efficiency, enhanced mRNA recovery, and improved stability against RNase	21
Protein Diffusion in Electroporation‐Based Biopsy: Quantifying Protein Transport From Human Skin for Skin Liquid Sampling With Electroporation	21
Increasing yield of in vitro transcription reaction with at‐line high pressure liquid chromatography monitoring	21
Oxygen Consumption in Filamentous Pellets of Aspergillus niger: Microelectrode Measurements and Modeling	21
Advancing Malic Acid Production of Aspergillus oryzae : Combined Process Optimization and Application of Various Substrates	21
Substrate and nutrient manipulation during continuous cultivation of extremophilic algae, Galdieria spp. RTK 37.1, substantially impacts biomass productivity and composition	21
Recent Research on Chondrocyte Dedifferentiation and Insights for Regenerative Medicine	21
Engineered Bacterial Ligand From Streptococcus pneumoniae on Macroporous Resins for Selective Affinity Capture of Secretory IgA	21
Elucidating the effects of microbubble pinch‐off dynamics on mammalian cell viability	21
Open‐Source Anaerobic Digestion Modeling Platform, Anaerobic Digestion Model No. 1 Fast (ADM1F)	20
Effect of protein fouling on filtrate flux and virus breakthrough behaviors during virus filtration process	20
Multi‐cell‐line learning for the data‐driven construction of mechanistic metabolic models	20
Streamlined Clarification and Capture Process for Monoclonal Antibodies Using Fluidized Bed Centrifugation and Multi‐Column Chromatography With Membrane Adsorbers	20
A Label‐Free Rapid Fluorescence Screening Approach for Identifying Cell‐Penetrating Peptides Using ANS as an Extrinsic Probe	20
Single Cell Protein Production From Ethanol: Model‐Based Bioreactor Operation at Industrial Scale	20
Lactic acid bacteria as a tool for biovanillin production: A review	19
Development of a novel purification method for AAV vectors using tangential flow filtration	19
Efficient and precise control of gene expression in Geobacter sulfurreducens through new genetic elements and tools for pollutant conversion	19
Biotechnology and Bioengineering: Volume 122, Number 9, September 2025	19
Platform development for high‐throughput optimization of perfusion processes: Part I: Implementation of cell bleeds in microwell plates	19
Techno‐Economic Analysis of Membrane‐Based Purification Platforms for AAV Vector Production	19
Covalent organic frameworks (COFs) as carrier for improved drug delivery and biosensing applications	19
Enhanced harvest performance predictability through advanced multivariate data analysis of mammalian cell culture particle size distribution	19
Engineering dense tumor constructs via cellular contraction of extracellular matrix hydrogels	19
Continuous monitoring of IgG using immobilized fluorescent reporters	19
Characterization of Sterilizing‐Grade Membranes/Prefilters and Application to mRNA‐LNP Process Development	19
A proteomics approach to decipher a sticky CHO situation	19
Cover Image, Volume 121, Number 8, August 2024	19
Development of Raman Spectroscopy and Machine Learning Methods for Protein Aggregate Quantification: Application to BSA in Chromatographic Processes	19
H₂O₂ feeding enables LPMO‐assisted cellulose saccharification during simultaneous fermentative production of lactic acid	18
Optimized Biosynthetic Pathway for Nonnatural Amino Acids: An Efficient Approach for L‐2‐Aminobutyric Acid Production	18
Impact of Hormone on Growth and GA ₃ Regulation of Anthocyanin Biosynthesis in Suspension‐Culture Cells of Cyclocarya paliurus	18
Engineering Escherichia coli asymmetry distribution‐based synthetic consortium for shikimate production	18
One‐Pot Hetero‐Di‐C‐Glycosylation of the Natural Polyphenol Phloretin by a Single C‐Glycosyltransferase With Broad Sugar Substrate Specificity	18
Model‐based control system design to manage process parameters in mammalian cell culture for biopharmaceutical manufacturing	18
Corrigendum to “High‐Throughput Investigation of Endothelial‐to‐Mesenchymal Transformation (EndMT) With Combinatorial Cellular Microarrays”	18
Engineering Yarrowia lipolytica for Efficient Production of Erythritol by Decoding and Harnessing Osmotic‐Stress‐Responsive Genetic Targets	18
A Paradigm of Computer Vision and Deep Learning Empowers the Strain Screening and Bioprocess Detection	18
Automated calibration and in‐line measurement of product quality during therapeutic monoclonal antibody purification using Raman spectroscopy	17
Validation and scalability of homemade polycaprolactone macrobeads grafted with thermo‐responsive poly(N‐isopropylacrylamide) for mesenchymal stem cell expansion and harvesting	17
Advanced cell technologies: Making protein, cell, and gene therapies a reality	17
Real‐Time Auto Controlling of Viable Cell Density in Perfusion Cultivation Aided by In‐Line Dielectric Spectroscopy With Segmented Adaptive PLS Model	17
Establishment of a Single‐Cell Minimal Medium: A Case Study for Microfluidic Cultivation of Corynebacterium glutamicum	17
Plant Cell Organoids of Catharanthus roseus : A Novel Biotechnological Platform for Vinblastine and Indole‐Derived Alkaloids	17
Deep hybrid modeling of a HEK293 process: Combining long short‐term memory networks with first principles equations	17
Resistive Method for Bacterial Detection Employing a Silicon Nanowire Electrical Chip	17
Cast‐Molded Channelized Hydrogel Scaffolds With Stereolithography‐Printed Templates	17
Fungal assisted bio‐treatment of environmental pollutants with comprehensive emphasis on noxious heavy metals: Recent updates	17
Monitoring and control of the release of soluble O₂ from H₂O₂ inside porous enzyme carrier for O₂ supply to an immobilized d‐amino acid oxidase	17
Biotechnology and Bioengineering: Volume 120, Number 10, October 2023	17
Effects of Air Temperature on Transient Expression of Influenza Hemagglutinin in Nicotiana benthamiana: Analysis of Transgene Transcription and Plant Stress Responses	17
Higher efficiency of vanadate iron in heterogeneous Fenton‐like systems to pretreat sugarcane bagasse and its enzymatic saccharification	16
An adaptive soft‐sensor for advanced real‐time monitoring of an antibody‐drug conjugation reaction	16
Engineering an Escherichia coli based in vivo mRNA manufacturing platform	16
Design an Energy‐Conserving Pathway for Efficient Biosynthesis of 1,5‐Pentanediol and 5‐Amino‐1‐Pentanol	16
Cover Image, Volume 121, Number 2, February 2024	16
Mesenchymal Stem Cells‐Derived Small Extracellular Vesicles and Their Validation as a Promising Treatment for Chondrosarcoma in a 3D Model in Vitro	16
Genome‐scale metabolic modeling of Thraustochytrium sp. RT2316‐16: Effects of nutrients on metabolism	16
Biotechnology and Bioengineering: Volume 120, Number 5, May 2023	16
Biotechnology and Bioengineering: Volume 121, Number 11, November 2024	16
Role of carbon nanotubes (CNTs) in transgenic plant development	16
Identification of yttrium oxide‐specific peptides for future recycling of rare earth elements from electronic scrap	16
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Modeling large‐scale bioreactors with diffusion equations. Part II: Characterizing substrate, oxygen, temperature, carbon dioxide, and pH profiles	16
A computational model for single cell Lamin‐A structural organization after microfluidic compression	16
Engineering a Perfusion Bioreactor System for hiPSC‐Derived Progenitor Co‐Culture Capturing Microglial Features in CNS Development	16

Perfusion Process Intensification for Lentivirus Production Using a Novel Scale‐Down Model	16
Biointerface engineering through amalgamation of gene technology and site‐specific growth factor conjugation for efficient osteodifferentiation	16
Biosynthesis of allantoin in Escherichia coli via screening a highly effective urate oxidase	16
Manipulation of mRNA translation elongation influences the fragmentation of a biotherapeutic Fc‐fusion protein produced in CHO cells	15
Hierarchical dynamic regulation of Saccharomyces cerevisiae for enhanced lutein biosynthesis	15
Succinic Acid Production by Engineered Mannheimia succiniciproducens and Its Use in Chemoenzymatic Poly(Butylene Succinate) Synthesis	15
Structure‐Guided Engineering of Alcohol Dehydrogenase for the Stereodivergent Synthesis of Amino Alcohols via Desymmetrization of Cyclic Diketones	15
Harnessing Cellular Feeling: Epigenetic to Mechanical Memory as a Framework for Stem Cell Manufacturing	15
Construction of a CRISPR‐Cas9‐Based Genetic Editing Tool for Serratia marcescens Using a Stationary Phase Promoter and Its Application in Putrescine Production	15
N₂‐fixation can sustain wastewater treatment performance of photogranules under nitrogen‐limiting conditions	15
Sensitivity analysis and adaptive mutation strategy differential evolution algorithm for optimizing enzymes' turnover numbers in metabolic models	15
Designer probiotics: Opening the new horizon in diagnosis and prevention of human diseases	15
Systems engineering Escherichia coli for efficient production p‐coumaric acid from glucose	15
Enzyme‐functionalized alginate microparticles enable anaerobic culture under ambient oxygen	15
Physiological metabolic topology analysis of Halomonas elongata DSM 2581^T in response to sodium chloride stress	15
Meso‐ and thermophilic posttreatment of press water coming from a thermophilic municipal solid waste digester	15
In Situ Microscopy for Real‐Time Visualization of Microcarrier Cell Cultures for Live Virus Vaccine Process Development	15
Interpretable‐AI‐Based Model Structural Transfer Learning to Accelerate Bioprocess Model Construction	15
Design space determination to optimize DNA complexation and full capsid formation in transient rAAV manufacturing	15
Less Is More: Practical Insights Into Multivariate Regression Models for Raman Spectroscopy in Bioprocess Monitoring	15
Plant extract‐based synthesis of metallic nanomaterials, their applications, and safety concerns	15
Scalable manufacturing platform for the production of PEGylated heme albumin	14
Exploring the potential of CRISPR/Cas genome editing for vegetable crop improvement: An overview of challenges and approaches	14
A multiscale modeling method for therapeutic antibodies in ion exchange chromatography	14
Transfer learning Bayesian optimization for competitor DNA molecule design for use in diagnostic assays	14
Fibrin gel enhanced trilayer structure in cell‐cultured constructs	14
Reducing Structural Nonidentifiabilities in Upstream Bioprocess Models Using Profile‐Likelihood	14
Integrated continuous biomanufacturing on pilot scale for acid‐sensitive monoclonal antibodies	14
Assessment of Anticancer Effects of Aloe vera on 3D Liver Tumor Spheroids in a Microfluidic Platform	14
Quorum sensing unveils the sludge floccule‐assisted stabilization of aerobic granules in granule‐dominated sequencing batch reactors	14
High‐level production of wild‐type and oxidation‐resistant recombinant alpha‐1‐antitrypsin in glycoengineered CHO cells	14
A New Aerosol‐Based Photobioreactor for the Cultivation of Cyanobacteria on Luffa	14
Adjustment of the main biosynthesis modules to enhance the production of l‐homoserine in Escherichia coli W3110	14
CFD‐based bioreactor model with proportional–integral–derivative controller functionality for dissolved oxygen and pH	14
Back Cover Image, Volume 120, Number 4, April 2023	14
Development of growth selection system and pocket engineering of d‐amino acid oxidase to enhance selective deamination activity toward d‐phosphinothricin	13
Recent advancements in enzyme‐incorporated nanomaterials: Synthesis, mechanistic formation, and applications	13
Fabrication of oxygen‐carrying microparticles functionalized with liver ECM‐proteins to improve phenotypic three‐dimensional in vitro liver assembly, function, and responses	13
Bayesian Optimization in Bioprocess Engineering—Where Do We Stand Today?	13
Cover Image, Volume 120, Number 3, March 2023	13
Controlling Enantioselectivity of Halohydrin Dehalogenase for Asymmetric Synthesis of Chiral Epichlorohydrin	13
Enhancing CHO cell productivity through a dual selection system using Aspg and Gs in glutamine free medium	13
Dual cytoplasmic‐peroxisomal engineering for high‐yield production of sesquiterpene α‐humulene in Yarrowia lipolytica	13
Impact of dual‐baculovirus infection on the Sf9 insect cell transcriptome during rAAV production using single‐cell RNA‐seq	13
Coevolving stability and activity of LsCR by a single point mutation and constructing neat substrate bioreaction system	13
Robust platform for inline Raman monitoring and control of perfusion cell culture	13
Modeling Analysis of Oxygen Transfer Efficiency in Rest Cell Catalysis for Extra High‐Titer Xylonic Acid Bioproduction	13
Inside Front Cover Image, Volume 122, Number 8, August 2025	13
A fluidized‐bed‐riser adsorption system for continuous bioproduct recovery from crude feedstock	13
Biotechnology and Bioengineering: Volume 120, Number 4, April 2023	13
Multiplexed Metabolic and Protein Engineering for D‐Limonene Overproduction in Saccharomyces cerevisiae	13
Early dynamic changes in iPSC oxygen consumption rate predict future cardiomyocyte differentiation	13
Directed Evolution of an (R)‐Selective Transaminase Toward Higher Efficiency of Sitagliptin Analog Biosynthesis	13
The Missing Link: Connecting Cultivation Conditions and Refolding Performance via Inclusion Body Biophysical Properties	13
Unsupervised Machine Learning‐Based Process Analytical Tools for Near Real‐Time Cell Morphology Analysis During CAR‐T Cell Manufacturing	13
Modular RNAi Pathway Engineering Enhances Plasmid Copy Number Control in Yeast Bioproduction System	13
Real‐time monitoring of biomass during Escherichia coli high‐cell‐density cultivations by in‐line photon density wave spectroscopy	13
Recent advances in biomedical applications of carbon and graphene quantum dots: A review	13
Biotechnology and Bioengineering: Volume 122, Number 1, January 2025	13
Real‐Time Monitoring of In Vitro Transcription for Production of mRNA Using Raman Spectroscopy	13
Insights into product and process related challenges of lentiviral vector bioprocessing	13
Constraint‐Based Metabolic Modeling of Synechococcus elongatus PCC 11801 and PCC 11802 for Photosynthetic Biomanufacturing	13
Protein fouling during constant‐flux virus filtration: Mechanisms and modeling	13
Physics‐informed neural networks for biopharmaceutical cultivation processes: Consideration of varying process parameter settings	13
Bioengineered 3D microfibrous‐matrix modulates osteopontin release from MSCs and facilitates the expansion of hematopoietic stem cells	12
Challenges and opportunities in downstream separation processes for mesenchymal stromal cells cultured in microcarrier‐based stirred suspension bioreactors	12
Predictive scaling of fiber‐based protein A capture chromatography using mechanistic modeling	12
Systematic review: External carbon source for biological denitrification for wastewater	12
Engineering Escherichia coli BL21 (DE3) for high‐yield production of germacrene A, a precursor of β‐elemene via combinatorial metabolic engineering strategies	12
Modeling the Performance of an Anaerobic Moving Bed Biofilm Reactor	12
Design and development of opto‐electrochemical biosensing devices for diagnosing chronic kidney disease	12
Psilocybin Production With Genetically Modified Aspergillus nidulans Under Pressurized Conditions	12
Enhanced acetate utilization for value‐added chemicals production in Yarrowia lipolytica by integration of metabolic engineering and microbial electrosynthesis	12
3D imaging and analysis to unveil the impact of microparticles on the pellet morphology of filamentous fungi	12
Enrichment of adeno‐associated virus serotype 5 full capsids by anion exchange chromatography with dual salt elution gradients	12
2,6‐diaminopurine (Z)‐containing toehold probes improve genotyping sensitivity	12
Technological advances in ocular trabecular meshwork in vitro models for glaucoma research	12
A kinetic framework for modeling oleochemical biosynthesis in Escherichia coli	12
Engineering of the Lrp/AsnC‐type transcriptional regulator DecR as a genetically encoded biosensor for multilevel optimization of L‐cysteine biosynthesis pathway in Escherichia coli	12
Engineering of reaction specificity, enantioselectivity, and catalytic activity of nitrilase for highly efficient synthesis of pregabalin precursor	11
Engineering of CoA‐Acylating Butyraldehyde Dehydrogenase for Enhanced 1,3‐Butanediol Production in Escherichia coli	11
Computational framework to understand the clinical stages of COVID‐19 and visualization of time course for various treatment strategies	11
Efficient One‐Step Production of 7S,17S‐ and 10S,17S‐Dihydroxydocosahexaenoic Acids by a Double‐Oxygenating 15S‐Lipoxygenase From Chlamydomonas incerta	11
Proteo‐Transcriptomic Analysis Reveals the Mechanisms Underlying Escherichia coli Phenotypic Shifts Under Blue Light	11
Sequential delivery of photosensitizers and checkpoint inhibitors by engineered bacteria for enhanced cancer photodynamic immunotherapy	11
Modeling large‐scale bioreactors with diffusion equations. Part I: Predicting axial dispersion coefficient and mixing times	11
Biotechnology and Bioengineering: Volume 119, Number 11, November 2022	11
Brain organoids: A revolutionary tool for modeling neurological disorders and development of therapeutics	11
Multi‐lipase gene knockdown in Chinese hamster ovary cells using artificial microRNAs to reduce host cell protein mediated polysorbate degradation	11
In situ biological particle analyzer based on digital inline holography	11
Identification and characterization of CHO host‐cell proteins in monoclonal antibody bioprocessing	11
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Plasmid‐Free CRISPR/Cpf1 Genome Editing With In Vivo T7 RNA Polymerase‐Transcribed CRISPR RNA From Short Double‐Stranded DNA	11
Production of zinc protoporphyrin IX by metabolically engineered Escherichia coli	11
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