OOIR: Observatory of International Research

Papers

(The H4-Index of Biotechnology and Bioengineering is 31. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Scale‐up economics for cultured meat	117
The role of extracellular DNA in the formation, architecture, stability, and treatment of bacterial biofilms	78
“High‐risk” host cell proteins (HCPs): A multi‐company collaborative view	76
Biogenesis and mechanisms of microRNA‐mediated gene regulation	70
Overview on immobilization of enzymes on synthetic polymeric nanofibers fabricated by electrospinning	52
Ultrahigh‐cell‐density heterotrophic cultivation of the unicellular green alga Chlorella sorokiniana for biomass production	50
A review of manufacturing capabilities of cell spheroid generation technologies and future development	49
A genome‐scale metabolic network model and machine learning predict amino acid concentrations in Chinese Hamster Ovary cell cultures	43
A common framework for integrated and continuous biomanufacturing	42
Modeling of photosynthesis and respiration rate for microalgae–bacteria consortia	41
End‐to‐end continuous bioprocessing: Impact on facility design, cost of goods, and cost of development for monoclonal antibodies	41
Manufacturing a chimpanzee adenovirus‐vectored SARS‐CoV‐2 vaccine to meet global needs	39
Production of β‐carotene in Saccharomyces cerevisiae through altering yeast lipid metabolism	39
Advances in mapping the epigenetic modifications of 5‐methylcytosine (5mC), N6‐methyladenine (6mA), and N4‐methylcytosine (4mC)	39
A CRISPR‐Cas12a‐derived biosensor enabling portable personal glucose meter readout for quantitative detection of SARS‐CoV‐2	39
Pilot‐scale demonstration of an end‐to‐end integrated and continuous biomanufacturing process	36
Construction of ajmalicine and sanguinarine de novo biosynthetic pathways using stable integration sites in yeast	35
Extraction, isolation, purification, derivatization, bioactivity, structure–activity relationship, and application of polysaccharides from White jellyfungus	35
Autofluorescence of blood and its application in biomedical and clinical research	35
Effect of alginate matrix engineered to mimic the pancreatic microenvironment on encapsulated islet function	34
Flux redistribution of central carbon metabolism for efficient production of l‐tryptophan in Escherichia coli	34
3D bioprinting and microscale organization of vascularized tissue constructs using collagen‐based bioink	33
Outer membrane vesicles (OMVs) enabled bio‐applications: A critical review	33
Production of trimeric SARS‐CoV‐2 spike protein by CHO cells for serological COVID‐19 testing	32
Dual cytoplasmic‐peroxisomal engineering for high‐yield production of sesquiterpene α‐humulene in Yarrowia lipolytica	32

The usage of composite nanomaterials in biomedical engineering applications	32
End‐to‐end collaboration to transform biopharmaceutical development and manufacturing	32
Functional expression of eukaryotic cytochrome P450s in yeast	32
Exploiting heterologous and endogenous CRISPR‐Cas systems for genome editing in the probiotic Clostridium butyricum	32
Miniaturized electrochemical biosensor based on whole‐cell for heavy metal ions detection in water	31
A transfer learning approach for predictive modeling of bioprocesses using small data	31
Microbial fatty acid transport proteins and their biotechnological potential	31
Maximizing mRNA vaccine production with Bayesian optimization	31