OOIR: Observatory of International Research

Papers

(The H4-Index of Biotechnology and Bioengineering is 30. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-03-01 to 2025-03-01.)

Article	Citations
Biotechnology and Bioengineering: Volume 121, Number 1, January 2024	117
Concentration‐dependent diffusion of unlabeled protein within an in vitro hyaluronic acid matrix	96
Biotechnology and Bioengineering: Volume 120, Number 8, August 2023	95
In‐silico media optimization for continuous cultures using genome scale metabolic networks: The case of CHO‐K1	90
	60
	59
Biotechnology and Bioengineering: Volume 119, Number 2, February 2022	50
	46
Biotechnology and Bioengineering: Volume 120, Number 4, April 2023	45
High‐Efficiency CRISPR‐Cas9 Genome Editing Unveils Biofilm Insights and Enhances Antimicrobial Activity in Bacillus velezensis FZB42	44
Modeling the Performance of an Anaerobic Moving Bed Biofilm Reactor	43
Machine Learning‐Powered Optimization of a CHO Cell Cultivation Process	43
pH Threshold Impacts Chalcopyrite Bioleaching Dynamics for the Extreme Thermoacidophile Sulfurisphaera ohwakuensis	42
Alterations in Protein Phosphorylation and Arginine Biosynthesis Metabolism Confer β‐Phenylethanol Tolerance in Saccharomyces cerevisiae	41
Online monitoring of methane transfer rates unveils nitrogen fixation dynamics in Methylococcus capsulatus	38
Rational design of short‐chain dehydrogenase/reductase for enantio‐complementary synthesis of chiral 1,2‐diols by successive hydroxymethylation and reduction of aldehydes	38
Miniature auto‐perfusion bioreactor system with spiral microfluidic cell retention device	37
Rational design of disulfide bonds to increase thermostability of Rhodococcus opacus catechol 1,2 dioxygenase	35
Advancements in nanobody generation: Integrating conventional, in silico, and machine learning approaches	35
Exploiting heterologous and endogenous CRISPR‐Cas systems for genome editing in the probiotic Clostridium butyricum	34
Magnetoelastic sensors for real‐time tracking of cell growth	34
Physics‐informed neural networks for biopharmaceutical cultivation processes: Consideration of varying process parameter settings	34
Peptide ligands for the universal purification of exosomes by affinity chromatography	34
High‐Efficiency Genome Editing in Naturally Isolated Aeromonas hydrophila and Edwardsiella Piscicida Using the CRISPR‐Cas9 System	33
Process analytical technology for on‐line monitoring of quality attributes during single‐use ultrafiltration/diafiltration	33

Application and progress of 3D tumor models in breast cancer	32
End‐to‐end continuous bioprocessing: Impact on facility design, cost of goods, and cost of development for monoclonal antibodies	32
Lactoyl leucine and isoleucine are bioavailable alternatives for canonical amino acids in cell culture media	31
Bioinformatics‐driven discovery of novel Clostridioides difficile lysins and experimental comparison with highly active benchmarks	31
Monitoring of the Biotechnological Production of Dihydroxyacetone Using a Low‐Field ¹H NMR Spectrometer	30