OOIR: Observatory of International Research

Papers

(The H4-Index of Biotechnology and Bioengineering is 32. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Concentration of clarified pool by single‐pass tangential flow filtration to improve productivity of protein A capture step: Impact of clarification strategies	70
	66
Optical discrimination of pathological red blood cells	62
	61
Continuous low pH viral inactivation: Operation and scaling strategy informs viral clearance study	55
	54
Computational fluid dynamics based digital twins of fixed bed bioreactors validate scaling principles for recombinant adeno‐associated virus gene therapy manufacturing	53
Elucidating the Interplay Between Resin Media, Feed Constituents, and Process Conditions in AAV Affinity Column Fouling With Confocal Microscopy	53
Biotechnology and Bioengineering: Volume 122, Number 12, December 2025	52
Application and progress of 3D tumor models in breast cancer	49
Genetically Programmed Control of Overflow Metabolism	48
Effects of biofilm heterogeneity on the apparent mechanical properties obtained by shear rheometry	44
Dynamic D‐Allose Monitoring Via a Toggle‐Programmed Microbial Fluorescent Biosensor	43
An engineered ultrahigh affinity bi‐paratopic uPAR targeting agent confers enhanced tumor targeting	43
Constructing multi‐enzymatic cascade reactions for selective production of 6‐bromoindirubin from tryptophan in Escherichia coli	43
Concentration‐dependent diffusion of unlabeled protein within an in vitro hyaluronic acid matrix	41
High‐throughput screening of optimal process conditions using model predictive control	39
Dual‐targeting multifunctional hyaluronic acid ligand‐capped gold nanorods with enhanced endo‐lysosomal escape ability for synergetic photodynamic–photothermal therapy of cancer	39
Engineered Stable, Antibiotic‐Free, High‐Level Protein Expression in the Probiotic Chassis Escherichia coli Nissle 1917	37
Dual‐Stage Cross‐Flow Filtration: Integrated Capture and Purification of Virus‐Like Particles	36
Designing the MyoFusion Media: A Serum‐Free Medium Optimized for Bovine Satellite Cell Differentiation	36
Engineering Plasmid‐Free Escherichia coli via Synergistic Metabolic Tuning and Fermentation Optimization for High‐Titer Salidroside Biosynthesis	35
Enhanced bioprocess control to advance the manufacture of mesenchymal stromal cell‐derived extracellular vesicles in stirred‐tank bioreactors	35
RSEA: A Web Server for Pathway Enrichment Analysis of Metabolic Reaction Sets	35
Current Advances and Future Prospects of Bulk and Microfluidic‐Enabled Electroporation Systems	35

Double‐reporter‐guided targeted activation of the oxytetracycline silent gene cluster in Streptomyces rimosus M527	35
Biotechnology and Bioengineering: Volume 122, Number 5, May 2025	34
Optimizing Pichia Pastoris Cell‐Free Protein Synthesis to Improve Economics	34
Heterologous Expression of Candida antarctica Lipase B in Aspergillus niger Using CRISPR/Cas9‐mediated Multi‐Gene Editing	34
Application of gas diffusion electrodes in bioeconomy: An update	33
Expression of filaments of the Geobacter extracellular cytochrome OmcS in Shewanella oneidensis	33
Iron in blood cells: Function, relation to disease, and potential for magnetic separation	33
Super7 passaging method to improve Chinese hamster ovary cell fed‐batch performance	32
Recent Advances in Laccase‐Based Nanobiocatalysts for Sustainable Bioremediation Applications	32