OOIR: Observatory of International Research

Papers

(The H4-Index of Biotechnology and Bioengineering is 33. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
	122
Super7 passaging method to improve Chinese hamster ovary cell fed‐batch performance	73
Optical discrimination of pathological red blood cells	54
An engineered ultrahigh affinity bi‐paratopic uPAR targeting agent confers enhanced tumor targeting	53
Back Cover Image, Volume 118, Number 11, November 2021	52
Continuous low pH viral inactivation: Operation and scaling strategy informs viral clearance study	51
Harnessing metabolic plasticity in CHO cells for enhanced perfusion cultivation	50
	48
Expression of filaments of theGeobacterextracellular cytochrome OmcS inShewanella oneidensis	46
	45
Heterologous Expression of Candida antarctica Lipase B in Aspergillus niger Using CRISPR/Cas9‐mediated Multi‐Gene Editing	44
Repressing expression of difficult‐to‐express recombinant proteins during the selection process increases productivity of CHO stable pools	43
Concentration‐dependent diffusion of unlabeled protein within an in vitro hyaluronic acid matrix	42
pH Threshold Impacts Chalcopyrite Bioleaching Dynamics for the Extreme Thermoacidophile Sulfurisphaera ohwakuensis	42
Computational fluid dynamics based digital twins of fixed bed bioreactors validate scaling principles for recombinant adeno‐associated virus gene therapy manufacturing	42
RSEA: A Web Server for Pathway Enrichment Analysis of Metabolic Reaction Sets	42
Constructing multi‐enzymatic cascade reactions for selective production of 6‐bromoindirubin from tryptophan in Escherichia coli	42
Dual‐targeting multifunctional hyaluronic acid ligand‐capped gold nanorods with enhanced endo‐lysosomal escape ability for synergetic photodynamic–photothermal therapy of cancer	41
Effects of biofilm heterogeneity on the apparent mechanical properties obtained by shear rheometry	41
Dual‐Stage Cross‐Flow Filtration: Integrated Capture and Purification of Virus‐Like Particles	40
Application and progress of 3D tumor models in breast cancer	39
Biotechnology and Bioengineering: Volume 122, Number 5, May 2025	36
Double‐reporter‐guided targeted activation of the oxytetracycline silent gene cluster in Streptomyces rimosus M527	36
Elucidating the Interplay Between Resin Media, Feed Constituents, and Process Conditions in AAV Affinity Column Fouling With Confocal Microscopy	35
Iron in blood cells: Function, relation to disease, and potential for magnetic separation	35

Application of gas diffusion electrodes in bioeconomy: An update	34
Evaluating potential of tissue‐engineered cryogels and chondrocyte derived exosomes in articular cartilage repair	34
Enhanced bioprocess control to advance the manufacture of mesenchymal stromal cell‐derived extracellular vesicles in stirred‐tank bioreactors	34
High‐throughput screening of optimal process conditions using model predictive control	34
Current Advances and Future Prospects of Bulk and Microfluidic‐Enabled Electroporation Systems	33
Concentration of clarified pool by single‐pass tangential flow filtration to improve productivity of protein A capture step: Impact of clarification strategies	33
Analyzing protein conjugation reactions for antibody‐drug conjugate synthesis using polarized excitation emission matrix spectroscopy	33
Continuous polyhydroxybutyrate production from biogas in an innovative two‐stage bioreactor configuration	33