Biochemistry

Article	Citations
The Impact of Disorder–Order Switching on Protein Sequence Evolution	175
AmorProt: Amino Acid Molecular Fingerprints Repurposing-Based Protein Fingerprint	119
Genome Engineering for Next-Generation Cellular Immunotherapies	108
Interaction of the Influenza A Virus NS1 Protein with the 5′-m7G-mRNA·eIF4E·eIF4G1 Complex	106
The Fascinating Intricacy of pSer/Thr-Specific Phosphatases and Their Higher-Order Complexes: Emerging Concepts	96
Molecular Insights into the Inhibition of Dialysis-Related β2m Amyloidosis Orchestrated by a Bispidine Peptidomimetic Analogue	79
Inside-Out Design of Zinc-Binding Proteins with Non-Native Backbones	73
Advancing the Biosynthetic and Chemical Understanding of the Carcinogenic Risk Factor Colibactin and Its Producers	61
RNA Polymerase Ribozyme That Recognizes the Template–Primer Complex through Tertiary Interactions	57
13C Electron Nuclear Double Resonance Spectroscopy-Guided Molecular Dynamics Computations Reveal the Structure of the Enzyme–Substrate Complex of an Active, N-Linked Glycosylated Lip	56
Human Translesion Synthesis Polymerases polκ and polη Perform Error-Free Replication across N2-dG Methyleugenol and Estragole DNA Adducts	51
Pseudouridimycin Biosynthesis: Biochemical Characterization of the Glucose–Methanol–Choline (GMC) Family Oxidoreductase, PumI	47
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C3- and C3/C5-Epimerases Required for the Biosynthesis of the Capsular Polysaccharides from Campylobacter jejuni	45
Modification of the 4Fe-4S Cluster Charge Transport Pathway Alters RNA Synthesis by Yeast DNA Primase	39
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Issue Editorial Masthead	30
Biochemical, Bioinformatic, and Structural Comparisons of Transketolases and Position of Human Transketolase in the Enzyme Evolution	30
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Multitasking Proteins: Exploring Noncanonical Functions of Proteins during Mitosis	29

Computational Approaches for Development of Engineered Therapeutics against SARS-CoV-2	29
Modifying the Basicity of the dNTP Leaving Group Modulates Precatalytic Conformational Changes of DNA Polymerase β	28
A High-Throughput Screening Pipeline to Identify Methyltransferase and Exonuclease Inhibitors of SARS-CoV-2 NSP14	27
Identification of Filamin A Mechanobinding Partner III: SAV1 Specifically Interacts with Filamin A Mechanosensitive Domain 21	27
Transient-State Kinetic Analysis of the RNA Polymerase II Nucleotide Incorporation Mechanism	26
Hysteresis in Hepatitis B Virus (HBV) Requires Assembly of Near-Perfect Capsids	25
Glycerol 3-Phosphate Dehydrogenase Catalyzed Hydride Transfer: Enzyme Activation by Cofactor Pieces	25
Parameterizing the Binding Properties of XNA Aptamers Isolated from a Low Stringency Selection	25
A Novel Gene Alignment in Dorea sp. AM58-8 Produces 7-Dehydroxy-3β Bile Acids from Primary Bile Acids	24
Putative Protein Interactome of the Rhomboid Protease RHBDL4	24
α-Helical Structure of Antimicrobial Peptides Enhances Their Activity through Molecular Surface Signatures	24
Two-Component System Sensor Kinase Inhibitors Target the ATP-Lid of PmrB to Disrupt Colistin Resistance in Acinetobacter baumannii	24
Electrostatic Interactions Dictate Bile Salt Hydrolase Substrate Preference	23
Structure and Mechanism of a Cold-Adapted Bacterial Lipase	22
Targeting Scaffolding Functions of Enzymes Using PROTAC Approaches	21
Contrasting Mechanisms of Aromatic and Aryl-Methyl Substituent Hydroxylation by the Rieske Monooxygenase Salicylate 5-Hydroxylase	21
Molecular Evolution and Origins of Antibiotic Resistance Genes	21
Determining the Sequence Dependency of Self-Assembly of Elastin-Like Peptides Using Short Peptide Analogues with Shuffled Repetitive Sequences	21
Distinguishing Different Hydrogen-Bonded Helices in Proteins by Efficient 1H-Detected Three-Dimensional Solid-State NMR	21
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The PqsE Active Site as a Target for Small Molecule Antimicrobial Agents against Pseudomonas aeruginosa	20
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Structural Insights into the Substrate Range of a Bacterial Monoamine Oxidase	20
Transient Prenyltransferase–Cyclase Association in Fusicoccadiene Synthase, an Assembly-Line Terpene Synthase	20
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CUP1 Metallothionein from HealthySaccharomyces cerevisiaeColocalizes to the Cytosol and Mitochondrial Intermembrane Space	20
Molecular Mechanism of Protein Arginine Deiminase 2: A Study Involving Multiple Microsecond Long Molecular Dynamics Simulations	19
Dehydrogenases in the Flavoprotein Amine Oxidoreductase Superfamily	19
Decoding Substrate Selectivity of an Archaeal RlmCD-like Methyltransferase Through Its Salient Traits	19
Identification of 2-Sulfonyl/Sulfonamide Pyrimidines as Covalent Inhibitors of WRN Using a Multiplexed High-Throughput Screening Assay	18
Anionic Lipids Confine Cytochrome c2 to the Surface of Bioenergetic Membranes without Compromising Its Interaction with Redox Partners	18
Biochemical Studies of Systemic Lupus Erythematosus-Associated Mutations in Nonreceptor Tyrosine Kinases Ack1 and Brk	18
Strong Protection by 4-Hydroxyestrone against Erastin-Induced Ferroptotic Cell Death in Estrogen Receptor-Negative Human Breast Cancer Cells: Evidence for Protein Disulfide Isomerase as a Mechanistic	18
MA’AT Analysis of Peptides: Conformational Equilibrium of Alanine Dipeptide in Aqueous Solution	18
Chemical Logic of Peptide Branching by Iterative Nonlinear Nonribosomal Peptide Synthetases	18
Drug–Membrane Interactions: Effects of Virus-Specific RNA-Dependent RNA Polymerase Inhibitors Remdesivir and Favipiravir on the Structure of Lipid Bilayers	18
Substrate Electronics Dominate the Rate of Reductive Dehalogenation Promoted by the Flavin-Dependent Iodotyrosine Deiodinase	18
A Highly Stable Engineered Disulfide Bond in the Dimer Interface of E. coli Orotate Phosphoribosyl Transferase Measures Cytosolic Redox Conditions in Yeast	18
Comparative Analysis of Corrinoid Profiles across Host-Associated and Environmental Samples	17
Pre-Steady-State Reactivity of Peptidylglycine Monooxygenase Implicates Ascorbate in Substrate Triggering of the Active Conformer	17
Mapping of Residues in Leishmanial Glyceraldehyde-3-phosphate Dehydrogenase Crucial for Binding to 3′-UTR of TNF-α mRNA	17
Collagen Alpha 1(XI) Amino-Terminal Domain Modulates Type I Collagen Fibril Assembly	17
Dihydropyrimidine Dehydrogenase from Escherichia coli: Evidence for the Catalytic Sequence	17
Conserved Residues at the Mtr4 C-Terminus Coordinate Helicase Activity and Exosome Interactions	17
Kinetic Regulation of the Mammalian Sterile 20-like Kinase 2 (MST2)	16
Identification and Characterization of a Bacterial Periplasmic Solute Binding Protein That Binds l -Amino Acid Amides	16
Activation of the Influenza B M2 Proton Channel (BM2)	16
Role of Ribosomal Protein bS1 in Orthogonal mRNA Start Codon Selection	16
What Drives Chorismate Mutase to Top Performance? Insights from a Combined In Silico and In Vitro Study	16

Structure–Function Analysis of the A1 Subunit of Shiga Toxin 2 with Peptides That Target the P-Stalk Binding Site and Inhibit Activity	16
Identification of an Intrinsically Disordered Region (IDR) in Arginyltransferase 1 (ATE1)	16
Energetic Diversity in the Electron-Transfer Pathways of Type I Photosynthetic Reaction Centers	15
Conformational Selection Governs Carrier Domain Positioning in Staphylococcus aureus Pyruvate Carboxylase	15
Determination of the Structure and Dynamics of the Fuzzy Coat of an Amyloid Fibril of IAPP Using Cryo-Electron Microscopy	15
Serine-Carboxyl Peptidases, Sedolisins: From Discovery to Evolution	15
Viral Dark Matter: Illuminating Protein Function, Ecology, and Biotechnological Promises	15
Structural Dynamics of the Methyl-Coenzyme M Reductase Active Site Are Influenced by Coenzyme F430 Modifications	15
Importance of Asparagine 202 in Manipulating Active Site Structure and Substrate Preference for Human CYP17A1	15
Human Protein-l-isoaspartate O-Methyltransferase Domain-Containing Protein 1 (PCMTD1) Associates with Cullin-RING Ligase Proteins	15
Glycerol-3-Phosphate Dehydrogenase: The K120 and K204 Side Chains Define an Oxyanion Hole at the Enzyme Active Site	15
How Sugars Protect Dry Protein Structure	15
Membrane-Catalyzed Aggregation of Islet Amyloid Polypeptide Is Dominated by Secondary Nucleation	15
RNA–Ligand Interactions Quantified by Surface Plasmon Resonance with Reference Subtraction	14
Structural Basis of Stereospecific Vanadium-Dependent Haloperoxidase Family Enzymes in Napyradiomycin Biosynthesis	14
Kinetic and Mechanistic Studies of Human Oligoadenylate Synthetase 1	14
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Inhibition of Mandelate Racemase by Boron-Based Inhibitors: Different Binding Modes for Benzoxaboroles Versus Boronic Acids	14
2′-Deoxy Guanosine Nucleotides Alter the Biochemical Properties of Ras	14
Genome Editing: The Future Begins!	14
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Antimalarial Delivery with a Ferritin-Based Protein Cage: A Step toward Developing Smart Therapeutics against Malaria	14
Phosphonoacetate Modifications Enhance the Stability and Editing Yields of Guide RNAs for Cas9 Editors	14
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ssDNA and ssRNA Promote Phase Condensation of SAMHD1	14
Bioinformatic, Enzymatic, and Structural Characterization of Trichuris suis Hexosaminidase HEX-2	13
Sad from Proteobacteria is a Structurally Distinct ALDH3 Enzyme Specialized for the Oxidation of Steroidal Aldehydes	13
Activation of Dithiolopyrrolone Antibiotics by Cellular Reductants	13
The Fragile X Protein Disordered Regions Bind a Novel RNA Target	13
Contrasting Effects of Temperature on Human Arylamine N-Acetyltransferase and Acetyl Coenzyme A Hydrolase Activities	13
Evidence for Stepwise Disruption of E. coli RNA Polymerase: λPR Promoter Contacts and Duplex Formation in Transcription Initiation	13
Role of Hydration and Amino Acid Interactions on the Ion Permeation Mechanism in the hNaV1.5 Channel	13
Defining Requirements for Heme Binding in PGRMC1 and Identifying Key Elements that Influence Protein Dimerization	13
Chemical Identification of [Fe(III)(OH)(H2O)]2+ Complex Ion at the Ferroxidase Active Site in Cryo-EM Maps	13
Correlating Conformational Equilibria with Catalysis in the Electron Bifurcating EtfABCX of Thermotoga maritima	13
A Tight-Knit Family: The Medium-Chain Dehydrogenase/Reductases of Monoterpene Indole Alkaloid Biosynthesis	13
Biochemical Analysis of the Regulatory Role of Gαo in the Conformational Transitions of Drosophila Pins	13
Insights into the Activation and Self-Association of Arrestin-1	13
Bifunctional Epimerase/Reductase Enzymes Facilitate the Modulation of 6-Deoxy-Heptoses Found in the Capsular Polysaccharides of Campylobacter jejuni	13
Role of the Palmitoyl Group and of the Amphipathic α Helix in the Membrane Binding of the C-Terminus of G-Protein Receptor Kinase 4α/β	13
Inter-domain Flexibility of Human Ser/Arg-Rich Splicing Factor 1 Allows Variable Spacer Length in Cognate RNA’s Bipartite Motifs	13
Targeting Polymeric Nanoparticles to Specific Cell Populations in the Liver	12
Human Archaea and Associated Metabolites in Health and Disease	12
Structure of the LarB–Substrate Complex and Identification of a Reaction Intermediate during Nickel-Pincer Nucleotide Cofactor Biosynthesis	12
Electrostatic Contribution to 19F Chemical Shifts in Fluorotryptophans in Proteins	12
Slow Dissociation from the PARP1–HPF1 Complex Drives Inhibitor Potency	12
A Soluble, Minimalistic Glycosylphosphatidylinositol Transamidase (GPI-T) Retains Transamidation Activity	12
Kinetic and Structural Characterization of a Flavin-Dependent Putrescine N-Hydroxylase from Acinetobacter baumannii	12
Structural, Spectroscopic, and Computational Insights from Canavanine-Bound and Two Catalytically Compromised Variants of the Ethylene-Forming Enzyme	12
Revisiting the Burden Borne by Fumarase: Enzymatic Hydration of an Olefin	12
Mitochondrial Dynamics of Bcl-2 Family Proteins during 17-β-Estradiol-Induced Apoptosis Correlate with the Malignancy of Endometrial Cancer Cells	12
Functional Role of an Unusual Transmembrane Acidic Residue in the Calcium Pump Regulator Myoregulin	12
Structural Framework for Analysis of CD4+ T-Cell Epitope Dominance in Viral Fusion Proteins	12
Structural Motifs at the Telomeres and Their Role in Regulatory Pathways	12
Adenylate Kinase-Catalyzed Reactions of AMP in Pieces: Specificity for Catalysis at the Nucleoside Activator and Dianion Catalytic Sites	12
Mechanisms of Peptide Agonist Dissociation and Deactivation of Adhesion G-Protein-Coupled Receptors	12
C-Terminal Basic Region of Troponin T Alters the Ca2+-Dependent Changes in Troponin I Interactions	12
Defining Factors that Influence the Stability of Tetrameric EgtB from Chloracidobacterium thermophilum: From pH Modulation to Affinity Tag Retention	11
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An Alkaliphilic Chitinase Unveils Environment-Dependent Variation in the Canonical Catalytic Machinery of Family-18 Glycoside Hydrolases	11
The Biochemical Impact of Extracting an Embedded Adenylate Kinase Domain Using Circular Permutation	11
More Pieces of the Puzzle: Transient State Analysis of Dihydroorotate Dehydrogenase B from Lactoccocus lactis	11
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Peptide-Based Strategies: Combating Alzheimer’s Amyloid β Aggregation through Ergonomic Design and Fibril Disruption	11
Cosolvent Dimethyl Sulfoxide Influences Protein–Ligand Binding Kinetics via Solvent Viscosity Effects: Revealing the Success Rate of Complex Formation Following Diffusive Protein–Ligand Encounter	11
Biochemical Characterization of GacI, a Bifunctional Glycosyltransferase–Phosphatase Enzyme Involved in Acarbose Biosynthesis in Streptomyces glaucescens GLA.O	11
Catalytic Activity of the Archetype from Group 4 of the FTR-like Ferredoxin:Thioredoxin Reductase Family Is Regulated by Unique S = 7/2 and S = 1/2 [4Fe–4S] Clusters	11
Structural Plasticity Allows Calumenin-1 to Moonlight as a Ca2+-Independent Chaperone: Pb2+ Enables Probing Alternate Inhibitory Conformation	11
Evaluation of Cooperative Binding of Histone Post-Translational Modifications and the Surrounding Sequence by Trimethyllysine Reader Proteins	11
Negative Cooperativity in the Mechanism of Prenylated-Flavin-Dependent Ferulic Acid Decarboxylase: A Proposal for a “Two-Stroke” Decarboxylation Cycle	11
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Ancestral Sequence Reconstruction of the Ethylene-Forming Enzyme	11
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The Chaperone-Active State of HdeB at pH 4 Arises from Its Conformational Rearrangement and Enhanced Stability Instead of Surface Hydrophobicity	11
AQP4-DARPin1: A Chimeric Antigen Based on Scaffold Protein DARPin for Efficient Detection of AQP4-IgG in NMOSD	11
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Predicting Antiviral Resistance Mutations in SARS-CoV-2 Main Protease with Computational and Experimental Screening	10
Structural Insights into the Advances and Mechanistic Understanding of Human Dicer	10
4,4-Difluoroproline as a Unique 19 F NMR Probe of Proline Conformation	10
Reaction Mechanism of the Terminal Plastoquinone QB in Photosystem II as Revealed by Time-Resolved Infrared Spectroscopy	10
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Design of Diverse Asymmetric Pockets in De Novo Homo-oligomeric Proteins	10
HUG Domain Is Responsible for Active Dimer Stabilization in an NrdJd Ribonucleotide Reductase	10
New Insights into the Mechanism of Action of L-681,217, a Medicinally Promising Polyketide Inhibitor of Bacterial Protein Translation	10
Protein Condensate Formation via Controlled Multimerization of Intrinsically Disordered Sequences	10
Alternative Role of B/b Knob–Hole Interactions in the Fibrin Assembly	10
LC3B Binds to the Autophagy Protease ATG4b with High Affinity Using a Bipartite Interface	10
DNA Sequence Specificity Reveals a Role of the HLTF HIRAN Domain in the Recognition of Trinucleotide Repeats	10
Post-Transcriptional Modifications of the Large Ribosome Subunit Assembly Intermediates in E. coli Expressing a Helicase-Inactive DbpA Variant	10
Atomistic Insights into Sequence-Mediated Spontaneous Association of Short RNA Chains	10
Phosphonate and α-Fluorophosphonate Analogues of d-Glucose 6-Phosphate as Active-Site Probes of 1l-myo-Inositol 1-Phosphate Synthase	10
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Insights into the Structure and Dynamics of Proteins from 19F Solution NMR Spectroscopy	10
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Biochemical Applications of Microbial Rare Glycan Biosynthesis, Recognition, and Sequencing	10
Parkinsonism-Associated Protein DJ-1 Is an Antagonist, Not an Eraser, for Protein Glycation	10
Bisubstrate Analog Inhibitors of DXP Synthase Show Species Specificity	10
The Engineered Hexosaminidase Tt OGA-D120N Is an Efficient O -/ N	10
Differential Interactions of the Proteasome Inhibitor PI31 with Constitutive and Immuno-20S Proteasomes	10
The RNA-Binding Domain of hnRNP U Extends beyond the RGG/RG Motifs	10
Sortase-Mediated Fluorescent Labeling of eIF4E for Investigating Translation Initiation Mechanisms	10
Discovery of a Potent Tat-Binding Antiretroviral Compound Using a Two-Step Screening Approach	10
Enzyme-Mediated Proximity Labeling Identifies Small RNAs in the Endoplasmic Reticulum Lumen	10
Mutational Analysis of (+)-Limonene Synthase	9
Exploring the Heterogeneous Structural Dynamics of Class II Lanthipeptide Synthetases with Hydrogen–Deuterium Exchange Mass Spectrometry (HDX-MS)	9
Single-Molecule Force Spectroscopy Reveals the Mechanical Role of p47 in Protein Stabilization	9
Identification and Functional Characterization of the Polymerizing Glycosyltransferase Required for the Transfer of d-Ribose to the d-GalfNAc Moiety of the Capsular Polysa	9
Time-Resolved Infrared Evidence for Protein Conformational Changes During the Dark-Rearrangement Process of Photosystem II Photoactivation: A Comparative Study of Solution and Crystal Samples	9
Dynamic Nuclear Polarization Illuminates Key Protein–Lipid Interactions in the Native Bacterial Cell Envelope	9
Structural Insights into Selectively Targeting Candida albicans Hsp90	9
Hypoxia Rewires Histone Methylation in Glioblastoma Cells via Enzyme Reprogramming Despite Disruption of One-Carbon Metabolism	9
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Hydrogen Bonding Compensation on the Convex Solvent-Exposed Helical Face of IA3, an Intrinsically Disordered Protein	9
Selenoprotein K Is a Peripheral ER Membrane Protein	9
Transcription Regulation of Flagellins: A Structural Perspective	9
Selective Inhibition of ADAR1 Using 8-Azanebularine-Modified RNA Duplexes	9
β2-Adrenergic Receptor Utilizes Distinct Interaction Interfaces to Selectively form Heterooligomers with a Subset of Bitter Taste Receptors	9
Glycerol 3-Phosphate Dehydrogenase: Role of the Protein Conformational Change in Activation of a Readily Reversible Enzyme-Catalyzed Hydride Transfer Reaction	9
Contribution of Proteorhodopsin to Light-Dependent Biological Responses in Hymenobacter nivis P3T Isolated from Red Snow in Antarctica	9
Structural Characteristics of Docosahexaenoic Acid and Eicosapentaenoic Acid Inhibiting Amyloid-β Fibrillation	9
Functional Validation of SAM Riboswitch Element A from Listeria monocytogenes	9
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Folding of Staphylococcal Nuclease Induced by Binding of Chemically Modified Substrate Analogues Sheds Light on Mechanisms of Coupled Folding/Binding Reactions	9
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Discovery and Characterization of a Novel Allosteric Small-Molecule Inhibitor of NADP+-Dependent Malic Enzyme 1	9
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Assessing Interferon Regulatory Factor 4 Complex Formation: Differential Behavior of Homocomplexes Versus Heterocomplexes Induced by Mutations	9
Biochemistry of Heat Shock Proteins From Human Intracellular Protozoan Parasites as Diagnostic and Therapeutic Biomarkers	9
18-Crown-6-ether Utilizes Distinct Allosteric Interactions to Uncouple Transport by the Multidrug Efflux Pump EmrE	9
Comparative Biochemical Studies of Disease-Associated Human Dicer Mutations on Processing of a Pre-microRNA and snoRNA	9
Pathway Specific Unbinding Free Energy Profiles of Ritonavir Dissociation from HIV-1 Protease	9
Sequence Divergence in the Arginase Domain of Ornithine Decarboxylase/Arginase in Fusobacteriacea Leads to Loss of Function in Oral Associated Species	9
Mammalian Commensal Streptococci Utilize a Rare Family of Class VI Lanthipeptide Synthetases to Synthesize Miniature Lanthipeptide-type Ribosomal Peptide Natural Products	9
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Deciphering the Regulatory Role and Molecular Interactions That Drive the Competence Regulon Quorum Sensing Circuitry in Streptococcus constellatus	9
Oxidative Activation of the Heme Nitric Oxide/Oxygen-Binding Protein (H-NOX) from Caulobacter crescentus	9
Biosynthesis of UDP-β-l-Arabinofuranoside for the Capsular Polysaccharides of Campylobacter jejuni	8
Alanine Scanning to Define Membrane Protein–Lipid Interaction Sites Using Native Mass Spectrometry	8
CD4+ T-Cell Epitope Prediction by Combined Analysis of Antigen Conformational Flexibility and Peptide-MHCII Binding Affinity	8
Aldol Cleavage in Water and the Power of Citrate Lyase as a Catalyst	8
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Extraction of In-Cell β-Amyloid Fibrillar Aggregates for Studying Molecular-Level Structural Propagations Using Solid-State NMR Spectroscopy	8
Cryo-Electron Microscopy Provides Mechanistic Insights into Solution-Dependent Polymorphism and Cross-Aggregation Phenomena of the Human and Rat Islet Amyloid Polypeptides	8
Biochemical Characterization and NMR Study of a PET-Hydrolyzing Cutinase from Fusarium solani pisi	8
Connected Chromatin Amplifies Acetylation-Modulated Nucleosome Interactions	8
Structure of the CD33 Receptor and Implications for the Siglec Family	8
Dissecting the Interaction between Cryptochrome and Timeless Reveals Underpinnings of Light-Dependent Recognition	8
Peroxiredoxins: Antioxidant Activity, Redox Relays, and Redox Signaling	8
Effects of Dimerization on the Deacylase Activities of Human SIRT2	8
Proteomics-Based Trapping to Study Substrates of Histone Deacetylase 6 Catalytic Domain 1	8
Recent Advances in Double-Strand Break-Free Kilobase-Scale Genome Editing Technologies	8
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CRDSAT under Heat: Balancing Stability, Affinity, and Functional Utility of Computationally Designed Tag Variants	8
Coupling Subunit-Specific States to Allosteric Regulation in Homodimeric Cyclooxygenase-2	8
Characterization of a Cleavable Fusion of Human CYP24A1 with Adrenodoxin Reveals the Variable Role of Hydrophobics in Redox Partner Binding	8
Identification of Kazal Inhibitor Scaffolds with Identical Canonical Binding Loops and Their Effects on Binding Properties	8
Slow Conformational Exchange between Partially Folded and Near-Native States of Ubiquitin: Evidence for a Multistate Folding Model	8
A Biparatopic Intrabody Renders Vero Cells Impervious to Ricin Intoxication	8
Fluorescence Light-Up of G4 DNA Structures Using Azlactone-Based Probes	8
Membrane Binding and Cholesterol Sensing Motif in Mycoplasma genitalium FtsZ: A Novel Mode of Membrane Recruitment for Bacterial FtsZ	8
Crystal Structure of Caryolan-1-ol Synthase, a Sesquiterpene Synthase Catalyzing an Initial Anti-Markovnikov Cyclization Reaction	8
Prion Protein Octarepeat Domain Forms Transient β-Sheet Structures upon Residue-Specific Binding to Cu(II) and Zn(II) Ions	8
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Cooperative Mismatch Discrimination by PNA and DNAzyme Enables High-Fidelity Cleavage of Plasmid DNA	8
Precision Interdiction of α-Synuclein Folding Pathways by Molecular Tweezers	8
Engineered Chimeras Unveil Swappable Modular Features of Fatty Acid and Polyketide Synthase Acyl Carrier Proteins	8
Insertions and Deletions (Indels): A Missing Piece of the Protein Engineering Jigsaw	8
Aromatic Ring Fluorination Patterns Modulate Inhibitory Potency of Fluorophenylhydroxamates Complexed with Histone Deacetylase 6	8
Targeting Bacterial RNA Polymerase: Harnessing Simulations and Machine Learning to Design Inhibitors for Drug-Resistant Pathogens	8
Lipids and EGCG Affect α-Synuclein Association and Disruption of Nanodiscs	8