OOIR: Observatory of International Research

Papers

(The H4-Index of Biochemistry is 28. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Kinetic and Structural Characterization of the Self-Labeling Protein Tags HaloTag7, SNAP-tag, and CLIP-tag	95
Modulating α-Synuclein Liquid–Liquid Phase Separation	93
Genetic Code Expansion: A Brief History and Perspective	81
Clustering of Aromatic Residues in Prion-like Domains Can Tune the Formation, State, and Organization of Biomolecular Condensates	72
Molecular Glues: The Adhesive Connecting Targeted Protein Degradation to the Clinic	70
Comparative Perturbation-Based Modeling of the SARS-CoV-2 Spike Protein Binding with Host Receptor and Neutralizing Antibodies: Structurally Adaptable Allosteric Communication Hotspots Define Spike Si	68
The Biochemical Landscape of Riboswitch Ligands	61
Ligandability of E3 Ligases for Targeted Protein Degradation Applications	59
Cysteine Oxidation in Proteins: Structure, Biophysics, and Simulation	56
Principles Governing the Phase Separation of Multidomain Proteins	56
Biochemical Mechanisms Underlying Psychedelic-Induced Neuroplasticity	54
Site-Specific Steric Control of SARS-CoV-2 Spike Glycosylation	52
Exploring the Mechanism of Covalent Inhibition: Simulating the Binding Free Energy of α-Ketoamide Inhibitors of the Main Protease of SARS-CoV-2	50
Topoisomerase II Poisons: Converting Essential Enzymes into Molecular Scissors	49
Cryo-EM Structure of the Rhodobacter sphaeroides Light-Harvesting 2 Complex at 2.1 Å	44
Biochemical Validation of a Fourth Guanidine Riboswitch Class in Bacteria	40
Liquid–Liquid Phase Separation in Biology: Specific Stoichiometric Molecular Interactions vs Promiscuous Interactions Mediated by Disordered Sequences	36
Ancestral Sequence Reconstruction Identifies Structural Changes Underlying the Evolution of Ideonella sakaiensis PETase and Variants with Improved Stability and Activity	36
Modeling Immunity with Rosetta: Methods for Antibody and Antigen Design	33
Fast and Specific Peroxygenase Reactions Catalyzed by Fungal Mono-Copper Enzymes	32
Dynamic Connection between Enzymatic Catalysis and Collective Protein Motions	31
Glycine-Rich Peptides from FUS Have an Intrinsic Ability to Self-Assemble into Fibers and Networked Fibrils	31
Functional Roles of Chelated Magnesium Ions in RNA Folding and Function	31
The Origin of Lipid Rafts	30
Predicting Antiviral Resistance Mutations in SARS-CoV-2 Main Protease with Computational and Experimental Screening	30

Mechanisms of O₂ Activation by Mononuclear Non-Heme Iron Enzymes	29
Improved Bst DNA Polymerase Variants Derived via a Machine Learning Approach	29
Enabling Role of Ligand-Driven Conformational Changes in Enzyme Evolution	29
Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to GalNAc and the Tumor-Associated Tn Antigen	28
Low Intrinsic Efficacy Alone Cannot Explain the Improved Side Effect Profiles of New Opioid Agonists	28
Targeted Degradation of the Oncogenic Phosphatase SHP2	28