Biochemical Pharmacology

Article	Citations
ALKBH7 mediates the mitigative effect of bismuth drug against cisplatin-induced acute kidney injury	316
Editorial Board	272
Editorial Board	243
Diabetes and the fabkin complex: A dual-edged sword	158
Identification of a dual JAK3/TEC family kinase inhibitor for atopic dermatitis therapy	155
PGC‐1α activation ameliorates cancer-induced bone pain via inhibiting apoptosis of GABAergic interneurons	133
Alisol A 24-Acetate combats Methicillin-Resistant Staphylococcus aureus infection by targeting the mevalonate biosynthesis	128
Unveiling ODP4: A breakthrough in PCOS treatment via BAT transplantation	125
Ammonium tetrathiomolybdate attenuates acetaminophen-induced acute liver failure by inhibiting the TRPV4/Calcium/NF-κB signaling pathway	112
PLK-3-mediated phosphorylation of BAP1 prevents diabetic retinopathy	105
A novel L-shaped ortho-quinone analog as PLK1 inhibitor blocks prostate cancer cells in G2 phase	102
Corrigendum to “Dose-dependent regulation of mitochondrial function and cell death pathway by sorafenib in liver cancer cells” [Biochem. Pharmacol. 176 (2020) 113902]	98
Corrigendum to “Targeting AhR suppresses hepatocyte ferroptosis in MASH by regulating the Pten/Akt/β catenin axis” [Biochem. Pharmacol. 232 (2025) 116711]	97
Decreased HMGB1 expression contributed to cutaneous toxicity caused by lapatinib	96
Influence of tumor microenvironment on the different breast cancer subtypes and applied therapies	95
Inhibition of circular RNA ASPH reduces the proliferation and promotes the apoptosis of hepatic stellate cells in hepatic fibrosis	86
Renoprotective effect of Nesfatin-1 in Adenine-Induced Chronic kidney Disease: An in vitro and in vivo study	85
CircDUSP16 mediates the effect of triple-negative breast cancer in pirarubicin via the miR-1224-3p/TFDP2 axis	81
IP3R-dependent Ca2+ signaling in the endoplasmic reticulum is required for deoxynivalenol-induced intestinal stem cell injury	79
ALDH1A1 confers resistance to RAF/MEK inhibitors in melanoma cells by maintaining stemness phenotype and activating PI3K/AKT signaling	73
Indole selectively suppresses aldosterone overproduction via binding to the catalytic site of CYP11B2	72
An organogold compound impairs Leishmania amazonensis amastigotes survival and delays lesion progression in murine cutaneous leishmaniasis: Mechanistic insights	70
Design, synthesis and anti-tumor activity of novel benzothiophenonaphthalimide derivatives targeting mitochondrial DNA (mtDNA) G-quadruplex	69
A variety of cytochrome P450 enzymes and flavin-containing monooxygenases in dogs and pigs commonly used as preclinical animal models	66
Emerging role of m6A modification in fibrotic diseases and its potential therapeutic effect	66

CD73 mitigates hepatic damage in alcoholic steatohepatitis by regulating PI3K/AKT-mediated hepatocyte pyroptosis	64
PXR as the tipping point between innate immune response, microbial infections, and drug metabolism	64
Metformin exhibits inhibitory effects on ferroptosis and alleviates chondrocyte metabolic imbalance in osteoarthritis models, as well as Erastin-induced ferroptosis, through the modulation of the P53/	63
Growth factor receptor-bound protein 2-mediated corneal epithelial injury drives depression-associated dry eye disease	62
Ultraviolet-treated riboflavin alleviates atopic dermatitis by inhibiting NLRP3 inflammasome activation and M1 macrophage polarization via histone lactylation	62
Peptide GLP-1 receptor agonists: From injection to oral delivery strategies	61
Histone deacetylase 6 modulates autophagy through HIF-1α/BNIP3 signaling in lung cancer	60
Dual roles of Makorin ring finger protein 1 in ubiquitination and RNA biology: regulatory mechanisms and therapeutic implications in human diseases	60
Luteolin binds Src, promotes STAT3 protein ubiquitination and exerts anti-melanoma effects in cell and mouse models	60
Cytochrome P450 2E1 gene knockout or inhibition prevents obesity induced by high-fat diet via regulating energy expenditure	59
AMPK-activation by catecholamines induces autophagy and cell proliferation in cardiac fibroblasts	58
Corrigendum to “Inhibition of CISD1 attenuates cisplatin-induced hearing loss in mice via the PI3K and MAPK pathways” [Biochem. Pharmacol. 223 (2024) 116132]	58
CDP-choline modulates cholinergic signaling and gut microbiota to alleviate DSS-induced inflammatory bowel disease	58
Bromodomain containing protein 4 (BRD4) and cancer therapy: A glimpse at dual-target drug development	57
Bile acids and bile acid activated receptors in the treatment of Covid-19	57
HDAC6 is involved in diabetic nephropathy by regulating TGFβ/Smads and NF-κB signaling pathways	56
Neuroanatomical distribution of fluorophores within adult RXFP3 Cre-tdTomato/YFP mouse brain	55
Restoring mitochondria–endoplasmic reticulum–synapse axis: a proteomic dissection of Rhein’s multi-pathway antidepressant mechanism	55
Methionine cycle in nonalcoholic fatty liver disease and its potential applications	54
Modulation of contextual fear acquisition and extinction by acute and chronic relaxin-3 receptor (RXFP3) activation in the rat retrosplenial cortex	54
RNA-binding protein GIGYF2 promotes colorectal cancer progression through activation of the METTL3/SERP1/STAT3 axis in an m6A-IGF2BP2-dependent manner	53
LINC00324 promotes cell proliferation and metastasis of esophageal squamous cell carcinoma through sponging miR-493-5p via MAPK signaling pathway	52
Melatonin protects vascular homeostasis by restoring PVAT redox balance in arterial hypertension	52
The potent role of Src kinase-regulating glucose metabolism in cancer	52
Investigation of the role and mechanism of dapagliflozin in mitigating renal injury in rats afflicted with diabetic kidney disease	51
SEMA7A orchestrates the colorectal cancer tumor microenvironment via PlexinC1: coordinating angiogenesis and macrophage M2 polarization	50
Pharmacological inhibition of HDAC6 suppresses NLRP3 inflammasome-mediated IL-1β release	50
Cellular crosstalk in doxorubicin-induced cardiotoxicity: underlying mechanisms and therapeutic strategies	49
Exploring the mechanism of nonylphenol-induced myocardial fibrosis based on TGF-β1/Smads signaling pathway	49
Sodium aescinate induces renal cell ferroptosis through the ATF4/CTH/SQOR axis	49
The rare bile acid isoallolithocholic acid (IALCA) is an EphA2 antagonist sparing FXR and TGR5 receptors	47
The relationship between tumor metabolism and 5-fluorouracil resistance	47
EP3 promotes macrophage M1-polarization to play a critical role in diabetic renal injury	47
Inflammation-induced promoter hypermethylation of GLP-1R limits the protective effect of GLP-1R agonists against acute lung injury	46
ALA-PDT augments intense inflammation in the treatment of acne vulgaris by COX2/TREM1 mediated M1 macrophage polarization	45
Exploring tryptophan metabolism: The transition from disturbed balance to diagnostic and therapeutic potential in metabolic diseases	45
Evidence for the contribution of vasopressin V1B receptors in the pathophysiology of depression	45
Interplay between the renin angiotensin system and oxidative stress contributes to alcohol addiction by stimulating dopamine accumulation in the mesolimbic pathway	45
Butyrolactone I from Aspergillus fungi blocks neutrophil FPR1 to alleviate acute respiratory distress syndrome	45
Recent trends in fragment-based anticancer drug design strategies against different targets: A mini-review	45
Natural product Eriocalyxin B suppressed triple negative breast cancer metastasis both in vitro and in vivo	44
Editorial Board	44
Exploring the glycation association with dyslipidaemia: Novel approach for diabetic nephropathy	44
Treatment with S-adenosylmethionine ameliorates irinotecan-induced intestinal barrier dysfunction and intestinal microbial disorder in mice	44
Sleep deprivation exacerbates experimental colitis via down-regulating the clock gene Per2	44
GRHL3 drives radiotherapy resistance and blocks the anti-tumor response of NK and CD4+ T cells in lung squamous cell carcinoma via RNF2	44
ACE1-targeting peptide Acein ameliorates UV-induced skin damage and aging in vivo and in vitro via downregulation of the pro-aging factor CLEC4G	43
Targeting non-coding RNAs and N6-methyladenosine modification in hepatocellular carcinoma	43
Systematic review and synthesis without meta-analysis (SWiM) reveals lack of clinical studies and weak preclinical evidence for interaction between glucose regulating drugs and environmental contamina	42
Immunometabolic attributes and mitochondria-associated signaling of Tumor-Associated Macrophages in tumor microenvironment modulate cancer progression	42

Decoding the roles of CCL11 in human malignancies and clinical implications	42
Tumor Cells-derived exosomal CircRNAs: Novel cancer drivers, molecular mechanisms, and clinical opportunities	41
Dexmedetomidine alleviates anxiety-like behavior in mice following peripheral nerve injury by reducing the hyperactivity of glutamatergic neurons in the anterior cingulate cortex	41
Understanding resistance acquisition by Pseudomonas aeruginosa and possible pharmacological approaches in palliating its pathogenesis	40
Editorial Board	40
Macrophage scavenger receptor A1 antagonizes abdominal aortic aneurysm via upregulating IRG1	39
SMURF1 leads to the β-catenin signaling-mediated progression of esophageal squamous carcinoma by losing PATZ1-induced CCNG2 transcription	39
Otilonium Bromide acts as a selective USP28 inhibitor and exhibits cytotoxic activity against multiple human cancer cell lines	39
A modern approach to glioblastoma using temozolomide and nanoparticles carrier drug: a standard care of combination therapy and treatment	39
Torachrysone-8-O-β-d-glucoside mediates anti-inflammatory effects by blocking aldose reductase-catalyzed metabolism of lipid peroxidation products	39
Viral Vectors, Exosomes, and Vexosomes: Potential armamentarium for delivering CRISPR/Cas to cancer cells	37
Methyl-oxazolomycin A: A novel oxazolomycin analog with potent selective estrogen receptor degrading activity in breast cancer cells	37
LILRB4 as a novel immunotherapeutic target for multiple diseases	37
Effect of pharmacological heart failure drugs and gene therapy on Danon's cardiomyopathy	37
Corrigendum to “Almonertinib inhibits liver cancer progression by triggering autophagy-dependent ferroptosis through inhibition of the PI3K/Akt1/mTOR pathway”. [Biochem. Pharmacol. 245 (2026) 117628]	36
Translational potential of targeting Anoctamin-1-Encoded Calcium-Activated chloride channels in hypertension	36
Inhibition of γ-secretase/Notch pathway as a potential therapy for reversing cancer drug resistance	36
Modulating UNC-51-like kinase 1 (ULK1) to treat diseases: A perspective from autophagic initiator to druggable target	36
Recent advances in studies on FtsZ inhibitors	36
Sirtuin1-p53: A potential axis for cancer therapy	36
6-O-angeloylplenolin inhibits osteoclastogenesis in vitro via suppressing c-Src/NF-κB/NFATc1 pathways and ameliorates bone resorption in collagen-induced arthritis mouse model	35
PPARα/δ dual agonist H11 alleviates diabetic kidney injury by improving the metabolic disorders of tubular epithelial cells	35
Physiological and pharmacological overview of the gonadotropin releasing hormone	35
The role of metabolic reprogramming in inflammatory bone diseases	35
Astragaloside IV as a potent vWbp inhibitor: An innovative strategy to mitigate foodborne Staphylococcus aureus infections	35
Sonic Hedgehog pathway: molecular mechanisms and therapeutic potentials in ischemic stroke recovery	35
Activation of the Nrf2/HO-1/GPX4 pathway by cGAMP Mitigates oxidative stress and ferroptosis in ischaemic stroke	34
FGF2 drives osteosarcoma metastasis through activating FGFR1-4 receptor pathway-mediated ICAM-1 expression	34
Venom composition and bioactive RF-amide peptide toxins of the saddleback caterpillar, Acharia stimulea (Lepidoptera: Limacodidae)	34
Nodosin alleviates cholestatic liver injury by activation of SIRT1/FXR signaling pathway and inhibition of hepatic inflammation	34
Reynoutrin targets EphB4 to ameliorate hepatic glucose and lipid metabolic disorders in type 2 diabetes mellitus	33
Isoflavone glucoside genistin, an inhibitor targeting Sortase A and Listeriolysin O, attenuates the virulence of Listeria monocytogenes in vivo and in vitro	33
The short-chain fatty acid acetate modulates orexin/hypocretin neurons: A novel mechanism in gut-brain axis regulation of energy homeostasis and feeding	33
Circadian oscillator NPAS2 regulates diurnal expression and activity of CYP1A2 in mouse liver	33
GPR55: Physiological functions and therapeutic potential in depression	33
Macrophages at the Core: Metabolic shifts and renal cell cross-talk as key mediators in diabetic nephropathy	33
KDM6B knockdown alleviates sleep deprivation-induced cerebrovascular lesions in APP/PS1 mice by inhibiting PARP16 expression	33
Ursolic acid augments the chemosensitivity of drug-resistant breast cancer cells to doxorubicin by AMPK-mediated mitochondrial dysfunction	33
Peroxisome proliferator-activated receptor (PPAR) agonists as a potential therapy for inherited metabolic disorders	32
Inhibition of CXCR2 improves motor coordination through attenuating white matter lesions in Parkinson’s disease models	32
Identifying inhibitors of Trypanosoma cruzi nucleoside diphosphate kinase 1 as potential repurposed drugs for Chagas’ disease	32
Chrysophanol prevents IL-1β-Induced inflammation and ECM degradation in osteoarthritis via the Sirt6/NF-κB and Nrf2/NF-κB axis	32
The dual targeting effects of KD025 on casein kinase 2 and ROCK2 in a mouse model of diet-induced obesity	31
The value of neck adipose tissue as a predictor for metabolic risk in health and type 2 diabetes	31
Combination of two Na+ channel-inhibiting anticonvulsants lacosamide and phenytoin: An additive, synergistic, or antagonistic effect?	31
Carbon monoxide in cell signaling and potential therapeutics	31
Rosavidin protects against PM2.5-induced lung toxicity via inhibition of NLRP3 inflammasome-mediated pyroptosis by activating the PI3K/AKT pathway	31
Combining Sorafenib, Se-methylselenocysteine, and α-Ketoacid for synergistic cytotoxicity in Hepatocellular carcinoma cell lines	31
Mast cell activation induced by tamoxifen citrate via MRGPRX2 plays a potential adverse role in breast cancer treatment	31
Pyroptosis as a molecular bridge: linking gasdermin activation to enhanced anti-tumor immunity in immunotherapy	31
Knockdown of Galectin-9 alleviates rheumatoid arthritis through suppressing TNF-α-induced activation of fibroblast-like synoviocytes	31
Melatonin alleviates brain injury in copper-laden rats: Underlying benefits for Wilson’s disease	31
Development of bile acid activated receptors hybrid molecules for the treatment of inflammatory and metabolic disorders	31
Potential small effector molecules restoring cellular defects due to sialic acid biosynthetic enzyme deficiency: Pathological relevance to GNE myopathy	31
Immunomodulatory effects of antiangiogenic tyrosine kinase inhibitors in renal cell carcinoma models: Impact on following anti-PD-1 treatments	31
Epigallocatechin gallate relieves asthmatic symptoms in mice by suppressing HIF-1α/VEGFA-mediated M2 skewing of macrophages	30
Serum-derived extracellular vesicles mediate acquired multidrug resistance of MCF-7 breast cancer cells induced by chemotherapeutic drugs	30
Itaconate alleviates β2-microglobulin-induced cognitive impairment by enhancing the hippocampal amino-β-carboxymuconate-semialdehyde-decarboxylase/picolinic acid pathway	30
Icaritin enhances the antitumor efficacy of irinotecan by dual-targeting carboxylesterase 2 and p53 in vitro and in vivo	30
Treatment with anti-Hsp90 antibody mitigates fibronectin-related cardiac fibrosis induced by pressure overload in mice	30
Oleoylethanolamide alleviates hyperlipidaemia-mediated vascular calcification via attenuating mitochondrial DNA stress triggered autophagy-dependent ferroptosis by activating PPARα	30
Acyclovir resistance in herpes simplex viruses: Prevalence and therapeutic alternatives	29
Cytarabine-induced destabilization of MCL1 mRNA and protein triggers apoptosis in leukemia cells	29
Editorial Board	29
ALOX5 promotes autophagy-dependent ferroptosis by activating the AMPK/mTOR pathway in melanoma	29
Emerging roles of senolytics/senomorphics in HIV-related co-morbidities	29
Immunometabolism: Is cyanide a missing link between metabolic pathways and immune function?	29
Dual-specificity tyrosine phosphorylation-regulated kinase 1A promotes the inclusion of amyloid precursor protein exon 7	29
DEC1 deficiency promotes osteoclastic activity by augmenting NFATc1 signaling via transactivation and the Ca2+/calcineurin pathway	29
Discovery of a novel selective small molecule interleukin-36 receptor antagonist for inflammation and cancer	29
A review on the effect of COX-2-mediated mechanisms on development and progression of gastric cancer induced by nicotine	28
Unraveling the glioblastoma (GBM) tumor microenvironment: future perspective on targeted immunotherapy	28
Targeting PIM1 ameliorates sepsis-associated acute kidney injury through inhibiting ferroptosis	28
Circadian rhythm disturbance induces osteoarthritis in mice: Involvement of Clock and Bmal1 dysregulation and Pdgfa inhibition	28
Therapeutic of a white adipose tissue-specific bivalent aptamer in obesity	28
Engineering a long acting, non-biased relaxin agonist using Protein-in-Protein technology	28
xCT/Slc7a11 promotes pulmonary arterial hypertension by disrupting AMPKα suppression of mTOR activation	28
Ifosfamide alleviates autoimmune toxicity and enhances antitumor efficacy in melanoma immunotherapy	28
Possibility of averting cytokine storm in SARS-COV 2 patients using specialized pro-resolving lipid mediators	28
P4HA3 depletion induces ferroptosis and inhibits colorectal cancer growth by stabilizing ACSL4 mRNA	28

Targeting hematopoietic progenitor kinase 1 (HPK1) for tumor immunotherapy: advances in small molecule inhibitors	28
Leptin impairs the therapeutic efficacy of adipose-derived mesenchymal stem cells by inducing apoptosis through NLRP3 inflammasomes activation	28
Pharmacological inhibition of JNK-MAPK disrupts cigarette smoke-induced RUNX2/Galectin-3 -driven EMT and cancer stemness in lung adenocarcinoma cells	27
PCSK9 regulates myofibroblast transformation through the JAK2/STAT3 pathway to regulate fibrosis after myocardial infarction	27
Preclinical evaluation of new drug-drug interactions of lomitapide: A proposal for novel mechanism of interaction associated with lipid metabolic changes	27
Corrigendum to “DOCK2 contributes to endotoxemia-induced acute lung injury in mice by activating proinflammatory macrophages” [Biochem. Pharmacol. 184 (2021) 114399]	27
Rational two-round modification for developing isopeptide bond-containing antimicrobial peptide with enhanced stability and potent activity against multidrug-resistant gram-negative bacteria	27
SIRT6 regulates endothelium-dependent relaxation by modulating nitric oxide synthase 3 (NOS3)	27
Mitochondrial elongation confers protection against doxorubicin-induced cardiotoxicity	27
Protein prenylation in islet β-cell function in health and metabolic stress	27
Corrigendum to “Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase, in a rodent model of lung injury“ [Biochem. Pharmacol. 63(1) (2002)	27
Inhibiting Cytosine-Adenine-Guanine (CAG) repeat expansions as a therapeutic strategy for Huntington’s disease	27
Recent progress in developing ATR inhibitors as anticancer agents	27
Mefunidone ameliorates acute liver failure in mice by inhibiting MKK4-JNK pathway	27
Corrigendum to “Geraniol ameliorates acute liver failure induced by lipopolysaccharide/D-galactosamine via regulating macrophage polarization and NLRP3 inflammasome activation by PPAR-γ methylation Ge	27
CEMIP promotes small cell lung cancer proliferation by activation of glutamine metabolism via FBXW7/c-Myc-dependent axis	27
Role of sirtuins in hepatocellular carcinoma progression and multidrug resistance: Mechanistical and pharmacological perspectives	26
Targeting regulated chondrocyte death in osteoarthritis therapy	26
Maladaptive regeneration and metabolic dysfunction associated steatotic liver disease: Common mechanisms and potential therapeutic targets	26
Endogenous α-Klotho is a common target in atherosclerosis and calcific aortic valve disease	26
Positive programming of the GC-IGF1 axis mediates adult osteoporosis susceptibility in male offspring rats induced by prenatal dexamethasone exposure	26
Macrophage-derived human resistin promotes perivascular adipose tissue dysfunction in experimental inflammatory arthritis	26
Ponatinib exacerbate renal injury in systemic lupus erythematosus mouse model through PDGFR-PI3K/AKT pathway	26
Structure and function of the highly homologous deubiquitinases ubiquitin specific peptidase 25 and 28: Insights into their pathophysiological and therapeutic roles	26
Finding new analgesics: Computational pharmacology faces drug discovery challenges	25
Lactylation in colorectal cancer: From mechanism to clinical application	25
The critical roles of STING in mitochondrial homeostasis	25
IOX-1 suppresses metastasis of osteosarcoma by upregulating histone H3 lysine trimethylation	25
Non-covalent mTOR inhibition suppresses NLRP3-GSDMD inflammasome-mediated pyroptosis	25
Eicosanoids and Inflammation: A delicate balance of Pro-Inflammatory and Pro-Resolving mediators	25
Targeting fibroblast activation protein with chimeric antigen receptor macrophages	25
A review on tumor-targeting liposomes: Fabrication, mechanism and applications	25
Antibody-drug conjugates for non-small cell lung cancer: Advantages and challenges in clinical translation	25
Detailed resume of S-methyltransferases: Categories, structures, biological functions and research advancements in related pathophysiology and pharmacotherapy	25
PACS2 deficiency ameliorates hepatic steatosis via inhibition of the JNK signaling pathway in diabetic mice	25
A rational foundation for micheliolide-based combination strategy by targeting redox and metabolic circuit in cancer cells	25
Editorial Board	24
BMAL1 plays a crucial role in immune homeostasis during sepsis-induced acute lung injury	24
Mitomycin induced the senescence of alveolar epithelial cells by targeting peroxiredoxin I	24
Enhanced thermogenesis in PAS Kinase-deficient male mice	24
Mst1 inhibition mitigates steroid-induced femoral head osteonecrosis by modulating autophagy in bone microvascular endothelial cells	24
Eicosatrienoic acid inhibits estradiol synthesis through the CD36/FOXO1/CYP19A1 signaling pathway to improve PCOS in mice	24
Overview of the therapeutic strategies for ER positive breast cancer	24
Role of sodium taurocholate cotransporting polypeptide (NTCP) in HBV-induced hepatitis: Opportunities for developing novel therapeutics	24
Polo-like kinase 1 (PLK1) is a novel CARD14-binding protein in keratinocytes	24
Harmine suppresses pancreatic cancer through DYRK1A-mediated hyper-activated RAS/MAPK inhibition	24
Selective activation of cannabinoid receptors by cannabis terpenes	24
Canonical DDR activation by EMT inducing agent 5-Fluorouracil is modulated by a cannabinoid based combinatorial approach via inducing autophagy and suppression of vimentin expression	24
Citrulline activates adenosine receptors: New insight into metabolic pathways interaction	24
Chronic kidney disease-induced muscle atrophy: Molecular mechanisms and promising therapies	24
Editorial Board	24
Corrigendum to “Niacin accelerates skeletal muscle regeneration and enhances C2C12 differentiation by activating the PI3K/Akt signaling pathway” [Biochem. Pharmacol. 250 (2026) 118016]	24
Resolvin D3 improves the impairment of insulin signaling in skeletal muscle and nonalcoholic fatty liver disease through AMPK/autophagy-associated attenuation of ER stress	24
Targeting TDP-43-activated GRP78/endoplasmic reticulum stress axis suppresses triple-negative breast cancer progression	24
Metabolic activation of drugs by cytochrome P450 enzymes: Biochemical insights into mechanism-based inactivation by fibroblast growth factor receptor inhibitors and chemical approaches to attenuate re	24
Editorial Board	23
Targeted delivery of a colchicine analogue provides synergy with ATR inhibition in cancer cells	23
Selpercatinib attenuates bleomycin-induced pulmonary fibrosis by inhibiting the TGF-β1 signaling pathway	23
Extracellular nucleotides in smooth muscle contraction	23
Triflupromazine and tranylcypromine alleviate primary cisplatin resistance in lung adenocarcinoma by promoting LDHA-mediated AMBRA1 ubiquitination	23
A systematic review and meta-analysis of environmental contaminant exposure impacts on weight loss and glucose regulation during calorie-restricted diets in preclinical studies: Persistent organic pol	23
1,2,4-Trimethoxybenzene alleviates cognitive dysfunction in type 2 diabetes model rats by inhibiting NLRP3 inflammasome and restoring gut microbiota disorders	23
Coffee for the liver: a mechanistic approach	23
Anti-inflammatory mechanism of the MLKL inhibitor necrosulfonamide in LPS- or poly(I:C)-induced neuroinflammation and necroptosis	23
Inhibition of soluble epoxide hydrolase relieves adipose inflammation via modulating M1/M2 macrophage polarization to alleviate airway inflammation and hyperresponsiveness in obese asthma	23
Omega-3 polyunsaturated fatty acids alleviate hyperuricemic nephropathy by inhibiting renal pyroptosis through GPR120	23
Corrigendum to “Cardioprotective effects of melatonin and metformin against doxorubicin-induced cardiotoxicity in rats are through preserving mitochondrial function and dynamics” [Biochem. Pharmacol.	23
FXR agonists for colorectal and liver cancers, as a stand-alone or in combination therapy	23
The V-ATPase a3 subunit deficiency affects osteoarthritis via mTOR-Mediated autophagy levels in subchondral bone	23
Ubiquitin ligase TRIM63 regulates HOXA10 expression to mediate fatty acid β-oxidation and suppress lung adenocarcinoma metastasis	23
5-O-Methylvisammioside, a novel inhibitor of CNT2, improves hyperuricemia by inhibiting intestinal purine nucleoside absorption with a safe profile	23
Targeting the DYNLL2-PAK1 axis inhibits caspase-11-dependent pyroptosis to alleviate sepsis	23
LncRNA SNHG14 drives angiotensin-induced abdominal aortic aneurysm progression by regulating autophagy via the miR-27b-3p/Wnt/β-catenin/c-Myc axis	23
Mechanotransduction and the extracellular matrix: Key drivers of lung pathologies and drug responsiveness	22
Development of 6-methyl-4,5-dihydropyrazolo[3,4-d]pyrimidin-4-one derivatives as lead sigma-1 receptor inhibitor: synthesis and biological evaluation via MSI	22
Piezo1 promotes colitis progression by modulating the Nrf2/NF-κB/NLRP3 signaling pathway	22
Novel molecular insights into the role of CRH type 1 receptor in the pathophysiology of depression	22
An A-ring substituted evodiamine derivative with potent anticancer activity against human non-small cell lung cancer cells by targeting heat shock protein 70	22
Oridonin combined with cisplatin synergistically induces apoptosis by activating the NOXA-BCL2 axis in esophageal squamous cell carcinoma	22
The role of taurine through endoplasmic reticulum in physiology and pathology	22
PPARγ activation by fisetin mitigates vascular smooth muscle cell senescence via the mTORC2-FoxO3a-autophagy signaling pathway	22
Calcium saccharate/DUSP6 suppresses renal cell carcinoma glycolytic metabolism and boosts sunitinib efficacy via the ERK-AKT pathway	22
Cardiac human bitter taste receptors contain naturally occurring variants that alter function	22
Role of long non-coding RNAs in adipose tissue metabolism and associated pathologies	22
Enterogastric and enterohepatic recycling of dendrobine in rats: a novel disposition mechanism responsible for pharmacokinetic multiple peaks	22
Novel pharmacological inhibition of JMJD3 improves necrotizing enterocolitis by attenuating the inflammatory response and ameliorating intestinal injury	22
miR-486-5p-rich extracellular vesicles derived from patients with olanzapine-induced insulin resistance negatively affect glucose-regulating function	22
Discovery of novel carboxylesterase 2 inhibitors for the treatment of delayed diarrhea and ulcerative colitis	22
Iron supplementation protects against renal ischemia–reperfusion injury by enhancing mitochondrial respiratory complex assembly	22
Celastrol induces liver cancer cell death via TFEB-mediated lysosome activation and ROS-dependent ferroptosis	22
Estrogen dampens central cannabinoid receptor 1-mediated neuroexcitation and pressor response in conscious female rats	21
Integrated metabolomics and transcriptomics reveal the neuroprotective effect of nervonic acid on LPS-induced AD model mice	21
Activated microglia secretome and proinflammatory cytokines increase neuronal mu-opioid receptor signalling and expression	21
Corrigendum to “Apoptotic effects of mahanine on human leukemic cells are mediated through crosstalk between Apo-1/Fas signaling and the Bid protein and via mitochondrial pathways” [Biochem. Pharmacol	21
AdipoRon and ADP355, adiponectin receptor agonists, in Metabolic-associated Fatty Liver Disease (MAFLD) and Nonalcoholic Steatohepatitis (NASH): A systematic review	21