Biochemical Pharmacology

Article	Citations
Editorial Board	338
Editorial Board	304
Diabetes and the fabkin complex: A dual-edged sword	276
Identification of a dual JAK3/TEC family kinase inhibitor for atopic dermatitis therapy	176
PGC‐1α activation ameliorates cancer-induced bone pain via inhibiting apoptosis of GABAergic interneurons	142
Unveiling ODP4: A breakthrough in PCOS treatment via BAT transplantation	131
A novel L-shaped ortho-quinone analog as PLK1 inhibitor blocks prostate cancer cells in G2 phase	122
Corrigendum to “Dose-dependent regulation of mitochondrial function and cell death pathway by sorafenib in liver cancer cells” [Biochem. Pharmacol. 176 (2020) 113902]	118
Corrigendum to “Targeting AhR suppresses hepatocyte ferroptosis in MASH by regulating the Pten/Akt/β catenin axis” [Biochem. Pharmacol. 232 (2025) 116711]	112
Influence of tumor microenvironment on the different breast cancer subtypes and applied therapies	111
Dual roles of Makorin ring finger protein 1 in ubiquitination and RNA biology: regulatory mechanisms and therapeutic implications in human diseases	107
Histone deacetylase 6 modulates autophagy through HIF-1α/BNIP3 signaling in lung cancer	106
AMPK-activation by catecholamines induces autophagy and cell proliferation in cardiac fibroblasts	103
Corrigendum to “Inhibition of CISD1 attenuates cisplatin-induced hearing loss in mice via the PI3K and MAPK pathways” [Biochem. Pharmacol. 223 (2024) 116132]	99
HDAC6 is involved in diabetic nephropathy by regulating TGFβ/Smads and NF-κB signaling pathways	98
Neuroanatomical distribution of fluorophores within adult RXFP3 Cre-tdTomato/YFP mouse brain	86
RNA-binding protein GIGYF2 promotes colorectal cancer progression through activation of the METTL3/SERP1/STAT3 axis in an m6A-IGF2BP2-dependent manner	82
Modulation of contextual fear acquisition and extinction by acute and chronic relaxin-3 receptor (RXFP3) activation in the rat retrosplenial cortex	82
LINC00324 promotes cell proliferation and metastasis of esophageal squamous cell carcinoma through sponging miR-493-5p via MAPK signaling pathway	80
Melatonin protects vascular homeostasis by restoring PVAT redox balance in arterial hypertension	76
Renoprotective effect of Nesfatin-1 in Adenine-Induced Chronic kidney Disease: An in vitro and in vivo study	75
CircDUSP16 mediates the effect of triple-negative breast cancer in pirarubicin via the miR-1224-3p/TFDP2 axis	71
IP3R-dependent Ca2+ signaling in the endoplasmic reticulum is required for deoxynivalenol-induced intestinal stem cell injury	71
Indole selectively suppresses aldosterone overproduction via binding to the catalytic site of CYP11B2	67
Tspan4+ fibroblasts facilitate the development of NECSO in myocardial ischemia reperfusion through migrasomes-mediated Tnf-α autocrine and cardiomyocytes aldosterone generation	66

CD73 mitigates hepatic damage in alcoholic steatohepatitis by regulating PI3K/AKT-mediated hepatocyte pyroptosis	66
KLF2-Mediated Modulation of oxidative stress and pyroptosis by Vanillic acid in intervertebral disc degeneration	66
An organogold compound impairs Leishmania amazonensis amastigotes survival and delays lesion progression in murine cutaneous leishmaniasis: Mechanistic insights	66
ALKBH7 mediates the mitigative effect of bismuth drug against cisplatin-induced acute kidney injury	66
Butyrolactone I from Aspergillus fungi blocks neutrophil FPR1 to alleviate acute respiratory distress syndrome	65
Investigation of the role and mechanism of dapagliflozin in mitigating renal injury in rats afflicted with diabetic kidney disease	63
Growth factor receptor-bound protein 2-mediated corneal epithelial injury drives depression-associated dry eye disease	62
Fangchinoline derivative LYY-34 suppresses TNBC by inhibiting BLM DNA helicase from unfolding of c-MYC promoter G-quadruplex DNA	61
Tucatinib alleviates postmenopausal osteoporosis by suppressing osteoclast differentiation via regulating the DRP1/NFATc1/CTSK signaling pathway	60
The rare bile acid isoallolithocholic acid (IALCA) is an EphA2 antagonist sparing FXR and TGR5 receptors	59
Exploring the mechanism of nonylphenol-induced myocardial fibrosis based on TGF-β1/Smads signaling pathway	59
Recent trends in fragment-based anticancer drug design strategies against different targets: A mini-review	58
Interplay between the renin angiotensin system and oxidative stress contributes to alcohol addiction by stimulating dopamine accumulation in the mesolimbic pathway	58
Inhibition of circular RNA ASPH reduces the proliferation and promotes the apoptosis of hepatic stellate cells in hepatic fibrosis	58
Sodium aescinate induces renal cell ferroptosis through the ATF4/CTH/SQOR axis	57
Cytochrome P450 2E1 gene knockout or inhibition prevents obesity induced by high-fat diet via regulating energy expenditure	57
Restoring mitochondria–endoplasmic reticulum–synapse axis: a proteomic dissection of Rhein’s multi-pathway antidepressant mechanism	57
Diving into AA9-mediated transglutaminase 2 inhibition reveals ferroptosis as driver of anticancer effects	56
Targeting purinergic signaling and MTAP-associated metabolism in cancer: A functional immunometabolic convergence framework	56
Cellular crosstalk in doxorubicin-induced cardiotoxicity: underlying mechanisms and therapeutic strategies	54
PLK-3-mediated phosphorylation of BAP1 prevents diabetic retinopathy	54
Bromodomain containing protein 4 (BRD4) and cancer therapy: A glimpse at dual-target drug development	54
ALA-PDT augments intense inflammation in the treatment of acne vulgaris by COX2/TREM1 mediated M1 macrophage polarization	54
Evidence for the contribution of vasopressin V1B receptors in the pathophysiology of depression	54
The relationship between tumor metabolism and 5-fluorouracil resistance	52
The potent role of Src kinase-regulating glucose metabolism in cancer	52
Alisol A 24-Acetate combats Methicillin-Resistant Staphylococcus aureus infection by targeting the mevalonate biosynthesis	52
ALDH1A1 confers resistance to RAF/MEK inhibitors in melanoma cells by maintaining stemness phenotype and activating PI3K/AKT signaling	51
Exploring tryptophan metabolism: The transition from disturbed balance to diagnostic and therapeutic potential in metabolic diseases	51
Peptide GLP-1 receptor agonists: From injection to oral delivery strategies	51
Pharmacological inhibition of HDAC6 suppresses NLRP3 inflammasome-mediated IL-1β release	51
Ultraviolet-treated riboflavin alleviates atopic dermatitis by inhibiting NLRP3 inflammasome activation and M1 macrophage polarization via histone lactylation	50
Ammonium tetrathiomolybdate attenuates acetaminophen-induced acute liver failure by inhibiting the TRPV4/Calcium/NF-κB signaling pathway	50
PXR as the tipping point between innate immune response, microbial infections, and drug metabolism	49
Bile acids and bile acid activated receptors in the treatment of Covid-19	49
A variety of cytochrome P450 enzymes and flavin-containing monooxygenases in dogs and pigs commonly used as preclinical animal models	48
CDP-choline modulates cholinergic signaling and gut microbiota to alleviate DSS-induced inflammatory bowel disease	48
SEMA7A orchestrates the colorectal cancer tumor microenvironment via PlexinC1: coordinating angiogenesis and macrophage M2 polarization	48
Niclosamide reprograms macrophages and improves muscle integrity in Duchenne muscular dystrophy models	47
Emerging role of m6A modification in fibrotic diseases and its potential therapeutic effect	47
Metformin exhibits inhibitory effects on ferroptosis and alleviates chondrocyte metabolic imbalance in osteoarthritis models, as well as Erastin-induced ferroptosis, through the modulation of the P53/	46
EP3 promotes macrophage M1-polarization to play a critical role in diabetic renal injury	46
Editorial Board	45
Systematic review and synthesis without meta-analysis (SWiM) reveals lack of clinical studies and weak preclinical evidence for interaction between glucose regulating drugs and environmental contamina	44
Targeting non-coding RNAs and N6-methyladenosine modification in hepatocellular carcinoma	44
Editorial Board	44
GRHL3 drives radiotherapy resistance and blocks the anti-tumor response of NK and CD4+ T cells in lung squamous cell carcinoma via RNF2	44
SMURF1 leads to the β-catenin signaling-mediated progression of esophageal squamous carcinoma by losing PATZ1-induced CCNG2 transcription	43
Understanding resistance acquisition by Pseudomonas aeruginosa and possible pharmacological approaches in palliating its pathogenesis	43
Torachrysone-8-O-β-d-glucoside mediates anti-inflammatory effects by blocking aldose reductase-catalyzed metabolism of lipid peroxidation products	43

Viral Vectors, Exosomes, and Vexosomes: Potential armamentarium for delivering CRISPR/Cas to cancer cells	41
Itaconate alleviates β2-microglobulin-induced cognitive impairment by enhancing the hippocampal amino-β-carboxymuconate-semialdehyde-decarboxylase/picolinic acid pathway	41
Translational potential of targeting Anoctamin-1-Encoded Calcium-Activated chloride channels in hypertension	41
6-O-angeloylplenolin inhibits osteoclastogenesis in vitro via suppressing c-Src/NF-κB/NFATc1 pathways and ameliorates bone resorption in collagen-induced arthritis mouse model	41
Ursolic acid augments the chemosensitivity of drug-resistant breast cancer cells to doxorubicin by AMPK-mediated mitochondrial dysfunction	41
Corrigendum to “Almonertinib inhibits liver cancer progression by triggering autophagy-dependent ferroptosis through inhibition of the PI3K/Akt1/mTOR pathway”. [Biochem. Pharmacol. 245 (2026) 117628]	41
Epigallocatechin gallate relieves asthmatic symptoms in mice by suppressing HIF-1α/VEGFA-mediated M2 skewing of macrophages	41
FGF2 drives osteosarcoma metastasis through activating FGFR1-4 receptor pathway-mediated ICAM-1 expression	40
KDM6B knockdown alleviates sleep deprivation-induced cerebrovascular lesions in APP/PS1 mice by inhibiting PARP16 expression	40
Melatonin alleviates brain injury in copper-laden rats: Underlying benefits for Wilson’s disease	39
Combining Sorafenib, Se-methylselenocysteine, and α-Ketoacid for synergistic cytotoxicity in Hepatocellular carcinoma cell lines	39
Identifying inhibitors of Trypanosoma cruzi nucleoside diphosphate kinase 1 as potential repurposed drugs for Chagas’ disease	39
The dual targeting effects of KD025 on casein kinase 2 and ROCK2 in a mouse model of diet-induced obesity	39
Development of bile acid activated receptors hybrid molecules for the treatment of inflammatory and metabolic disorders	38
Rosavidin protects against PM2.5-induced lung toxicity via inhibition of NLRP3 inflammasome-mediated pyroptosis by activating the PI3K/AKT pathway	37
Pyroptosis as a molecular bridge: linking gasdermin activation to enhanced anti-tumor immunity in immunotherapy	37
Mast cell activation induced by tamoxifen citrate via MRGPRX2 plays a potential adverse role in breast cancer treatment	37
DEC1 deficiency promotes osteoclastic activity by augmenting NFATc1 signaling via transactivation and the Ca2+/calcineurin pathway	36
Astragaloside IV as a potent vWbp inhibitor: An innovative strategy to mitigate foodborne Staphylococcus aureus infections	36
Pharmacological and neurobehavioral evaluation of the bifunctional opioid peptide Gluten exorphin B5	36
Potential small effector molecules restoring cellular defects due to sialic acid biosynthetic enzyme deficiency: Pathological relevance to GNE myopathy	36
Icaritin enhances the antitumor efficacy of irinotecan by dual-targeting carboxylesterase 2 and p53 in vitro and in vivo	36
ACE1-targeting peptide Acein ameliorates UV-induced skin damage and aging in vivo and in vitro via downregulation of the pro-aging factor CLEC4G	36
Serum-derived extracellular vesicles mediate acquired multidrug resistance of MCF-7 breast cancer cells induced by chemotherapeutic drugs	36
Isoflavone glucoside genistin, an inhibitor targeting Sortase A and Listeriolysin O, attenuates the virulence of Listeria monocytogenes in vivo and in vitro	35
Treatment with anti-Hsp90 antibody mitigates fibronectin-related cardiac fibrosis induced by pressure overload in mice	35
PPARα/δ dual agonist H11 alleviates diabetic kidney injury by improving the metabolic disorders of tubular epithelial cells	34
Immunomodulatory effects of antiangiogenic tyrosine kinase inhibitors in renal cell carcinoma models: Impact on following anti-PD-1 treatments	34
Dexmedetomidine alleviates anxiety-like behavior in mice following peripheral nerve injury by reducing the hyperactivity of glutamatergic neurons in the anterior cingulate cortex	34
Macrophages at the Core: Metabolic shifts and renal cell cross-talk as key mediators in diabetic nephropathy	34
Exploring the glycation association with dyslipidaemia: Novel approach for diabetic nephropathy	34
Peroxisome proliferator-activated receptor (PPAR) agonists as a potential therapy for inherited metabolic disorders	34
Carbon monoxide in cell signaling and potential therapeutics	34
ALOX5 promotes autophagy-dependent ferroptosis by activating the AMPK/mTOR pathway in melanoma	33
Combination of two Na+ channel-inhibiting anticonvulsants lacosamide and phenytoin: An additive, synergistic, or antagonistic effect?	33
Natural product Eriocalyxin B suppressed triple negative breast cancer metastasis both in vitro and in vivo	33
Sonic Hedgehog pathway: molecular mechanisms and therapeutic potentials in ischemic stroke recovery	33
Inhibition of γ-secretase/Notch pathway as a potential therapy for reversing cancer drug resistance	33
The value of neck adipose tissue as a predictor for metabolic risk in health and type 2 diabetes	33
Sleep deprivation exacerbates experimental colitis via down-regulating the clock gene Per2	33
Nodosin alleviates cholestatic liver injury by activation of SIRT1/FXR signaling pathway and inhibition of hepatic inflammation	33
Immunometabolic attributes and mitochondria-associated signaling of Tumor-Associated Macrophages in tumor microenvironment modulate cancer progression	32
Dual-specificity tyrosine phosphorylation-regulated kinase 1A promotes the inclusion of amyloid precursor protein exon 7	32
The short-chain fatty acid acetate modulates orexin/hypocretin neurons: A novel mechanism in gut-brain axis regulation of energy homeostasis and feeding	32
Sirtuin1-p53: A potential axis for cancer therapy	32
GPR55: Physiological functions and therapeutic potential in depression	32
A modern approach to glioblastoma using temozolomide and nanoparticles carrier drug: a standard care of combination therapy and treatment	32
Unravelling the multi-faceted roles of microRNAs in non-apoptotic regulated cell death (RCD) to improve cancer therapy	32
LILRB4 as a novel immunotherapeutic target for multiple diseases	31
Regulation of OTULIN ubiquitination by RNF6 alleviates asthma via mitigating epithelial-mesenchymal transition‑like phenotypic changes	31
Recent advances in studies on FtsZ inhibitors	31
Circadian oscillator NPAS2 regulates diurnal expression and activity of CYP1A2 in mouse liver	31
Inhibition of CXCR2 improves motor coordination through attenuating white matter lesions in Parkinson’s disease models	31
Effect of pharmacological heart failure drugs and gene therapy on Danon's cardiomyopathy	30
Decoding the roles of CCL11 in human malignancies and clinical implications	30
Venom composition and bioactive RF-amide peptide toxins of the saddleback caterpillar, Acharia stimulea (Lepidoptera: Limacodidae)	30
Targeting HDAC6 mitigates diabetic nephropathy through modulation of oxidative stress, inflammatory pathways, and apoptotic signaling	30
Macrophage scavenger receptor A1 antagonizes abdominal aortic aneurysm via upregulating IRG1	30
Knockdown of Galectin-9 alleviates rheumatoid arthritis through suppressing TNF-α-induced activation of fibroblast-like synoviocytes	30
Activation of the Nrf2/HO-1/GPX4 pathway by cGAMP Mitigates oxidative stress and ferroptosis in ischaemic stroke	30
Modulating UNC-51-like kinase 1 (ULK1) to treat diseases: A perspective from autophagic initiator to druggable target	30
Reynoutrin targets EphB4 to ameliorate hepatic glucose and lipid metabolic disorders in type 2 diabetes mellitus	30
Otilonium Bromide acts as a selective USP28 inhibitor and exhibits cytotoxic activity against multiple human cancer cell lines	30
Treatment with S-adenosylmethionine ameliorates irinotecan-induced intestinal barrier dysfunction and intestinal microbial disorder in mice	30
Methyl-oxazolomycin A: A novel oxazolomycin analog with potent selective estrogen receptor degrading activity in breast cancer cells	30
Acyclovir resistance in herpes simplex viruses: Prevalence and therapeutic alternatives	30
Chrysophanol prevents IL-1β-Induced inflammation and ECM degradation in osteoarthritis via the Sirt6/NF-κB and Nrf2/NF-κB axis	30
The role of metabolic reprogramming in inflammatory bone diseases	30
Physiological and pharmacological overview of the gonadotropin releasing hormone	30
Oleoylethanolamide alleviates hyperlipidaemia-mediated vascular calcification via attenuating mitochondrial DNA stress triggered autophagy-dependent ferroptosis by activating PPARα	30
Ifosfamide alleviates autoimmune toxicity and enhances antitumor efficacy in melanoma immunotherapy	29
Targeting fibroblast activation protein with chimeric antigen receptor macrophages	29
Immunometabolism: Is cyanide a missing link between metabolic pathways and immune function?	29
Emerging roles of senolytics/senomorphics in HIV-related co-morbidities	29
Discovery of a novel selective small molecule interleukin-36 receptor antagonist for inflammation and cancer	29
Pharmacological inhibition of JNK-MAPK disrupts cigarette smoke-induced RUNX2/Galectin-3 -driven EMT and cancer stemness in lung adenocarcinoma cells	29
Therapeutic of a white adipose tissue-specific bivalent aptamer in obesity	29
Editorial Board	29
Overview of the therapeutic strategies for ER positive breast cancer	29
Maladaptive regeneration and metabolic dysfunction associated steatotic liver disease: Common mechanisms and potential therapeutic targets	29

A review on the effect of COX-2-mediated mechanisms on development and progression of gastric cancer induced by nicotine	29
xCT/Slc7a11 promotes pulmonary arterial hypertension by disrupting AMPKα suppression of mTOR activation	28
Mefunidone ameliorates acute liver failure in mice by inhibiting MKK4-JNK pathway	28
Inhibiting Cytosine-Adenine-Guanine (CAG) repeat expansions as a therapeutic strategy for Huntington’s disease	28
Engineering a long acting, non-biased relaxin agonist using Protein-in-Protein technology	28
Rational two-round modification for developing isopeptide bond-containing antimicrobial peptide with enhanced stability and potent activity against multidrug-resistant gram-negative bacteria	28
CEMIP promotes small cell lung cancer proliferation by activation of glutamine metabolism via FBXW7/c-Myc-dependent axis	28
Circadian rhythm disturbance induces osteoarthritis in mice: Involvement of Clock and Bmal1 dysregulation and Pdgfa inhibition	28
Leptin impairs the therapeutic efficacy of adipose-derived mesenchymal stem cells by inducing apoptosis through NLRP3 inflammasomes activation	28
Preclinical evaluation of new drug-drug interactions of lomitapide: A proposal for novel mechanism of interaction associated with lipid metabolic changes	28
Corrigendum to “Geraniol ameliorates acute liver failure induced by lipopolysaccharide/D-galactosamine via regulating macrophage polarization and NLRP3 inflammasome activation by PPAR-γ methylation Ge	28
P4HA3 depletion induces ferroptosis and inhibits colorectal cancer growth by stabilizing ACSL4 mRNA	28
Corrigendum to “Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase, in a rodent model of lung injury“ [Biochem. Pharmacol. 63(1) (2002)	27
Targeting hematopoietic progenitor kinase 1 (HPK1) for tumor immunotherapy: advances in small molecule inhibitors	27
Ailanthone targets the EGR3-SOCS2 regulatory pathway to suppress vasculogenic mimicry in prostate cancer	27
Corrigendum to “Niacin accelerates skeletal muscle regeneration and enhances C2C12 differentiation by activating the PI3K/Akt signaling pathway” [Biochem. Pharmacol. 250 (2026) 118016]	27
Positive programming of the GC-IGF1 axis mediates adult osteoporosis susceptibility in male offspring rats induced by prenatal dexamethasone exposure	27
Endogenous α-Klotho is a common target in atherosclerosis and calcific aortic valve disease	27
Antibody-drug conjugates for non-small cell lung cancer: Advantages and challenges in clinical translation	27
Role of sodium taurocholate cotransporting polypeptide (NTCP) in HBV-induced hepatitis: Opportunities for developing novel therapeutics	27
Corrigendum to “DOCK2 contributes to endotoxemia-induced acute lung injury in mice by activating proinflammatory macrophages” [Biochem. Pharmacol. 184 (2021) 114399]	27
Non-covalent mTOR inhibition suppresses NLRP3-GSDMD inflammasome-mediated pyroptosis	27
Ubiquitin-specific peptidase 51: A potential target in cancer progression and therapy	27
Mitomycin induced the senescence of alveolar epithelial cells by targeting peroxiredoxin I	27
Chronic kidney disease-induced muscle atrophy: Molecular mechanisms and promising therapies	26
PACS2 deficiency ameliorates hepatic steatosis via inhibition of the JNK signaling pathway in diabetic mice	26
Cytarabine-induced destabilization of MCL1 mRNA and protein triggers apoptosis in leukemia cells	26
Unraveling the glioblastoma (GBM) tumor microenvironment: future perspective on targeted immunotherapy	26
Finding new analgesics: Computational pharmacology faces drug discovery challenges	26
Nigakinone enhances FXR expression to synergize with irinotecan in suppressing colorectal cancer cells and xenografts	26
Targeting PIM1 ameliorates sepsis-associated acute kidney injury through inhibiting ferroptosis	26
The antihypertensive and cardiovascular effects of lawsone methyl ether in high salt-induced hypertensive rats are mediated through multiple pathways	26
Role of sirtuins in hepatocellular carcinoma progression and multidrug resistance: Mechanistical and pharmacological perspectives	26
IOX-1 suppresses metastasis of osteosarcoma by upregulating histone H3 lysine trimethylation	26
Recent progress in developing ATR inhibitors as anticancer agents	26
Targeting regulated chondrocyte death in osteoarthritis therapy	26
Ponatinib exacerbate renal injury in systemic lupus erythematosus mouse model through PDGFR-PI3K/AKT pathway	25
Possibility of averting cytokine storm in SARS-COV 2 patients using specialized pro-resolving lipid mediators	25
Lactylation in colorectal cancer: From mechanism to clinical application	25
Structure and function of the highly homologous deubiquitinases ubiquitin specific peptidase 25 and 28: Insights into their pathophysiological and therapeutic roles	25
Pharmacological targeting of cholesterol biosynthesis in cancer: Sterol intermediates, oxysterols, and sterol flux rewiring	25
Citrulline activates adenosine receptors: New insight into metabolic pathways interaction	25
PCSK9 regulates myofibroblast transformation through the JAK2/STAT3 pathway to regulate fibrosis after myocardial infarction	25
The critical roles of STING in mitochondrial homeostasis	25
Mitochondrial elongation confers protection against doxorubicin-induced cardiotoxicity	25
BMAL1 plays a crucial role in immune homeostasis during sepsis-induced acute lung injury	25
Macrophage-derived human resistin promotes perivascular adipose tissue dysfunction in experimental inflammatory arthritis	25
Protein prenylation in islet β-cell function in health and metabolic stress	25
Editorial Board	25
A review on tumor-targeting liposomes: Fabrication, mechanism and applications	25
Eicosanoids and Inflammation: A delicate balance of Pro-Inflammatory and Pro-Resolving mediators	25
Detailed resume of S-methyltransferases: Categories, structures, biological functions and research advancements in related pathophysiology and pharmacotherapy	25
SIRT6 regulates endothelium-dependent relaxation by modulating nitric oxide synthase 3 (NOS3)	25
Editorial Board	25
Polo-like kinase 1 (PLK1) is a novel CARD14-binding protein in keratinocytes	25
5-O-Methylvisammioside, a novel inhibitor of CNT2, improves hyperuricemia by inhibiting intestinal purine nucleoside absorption with a safe profile	24
Omega-3 polyunsaturated fatty acids alleviate hyperuricemic nephropathy by inhibiting renal pyroptosis through GPR120	24
Editorial Board	24
Resolvin D3 improves the impairment of insulin signaling in skeletal muscle and nonalcoholic fatty liver disease through AMPK/autophagy-associated attenuation of ER stress	24
Activated microglia secretome and proinflammatory cytokines increase neuronal mu-opioid receptor signalling and expression	24
Pharmacologic modulation of the SAT1–N1-acetylspermidine axis is associated with enhanced chemotherapy cytotoxicity in T-LBL/ALL cells	24
FXR agonists for colorectal and liver cancers, as a stand-alone or in combination therapy	24
Extracellular nucleotides in smooth muscle contraction	24
Triflupromazine and tranylcypromine alleviate primary cisplatin resistance in lung adenocarcinoma by promoting LDHA-mediated AMBRA1 ubiquitination	24
Mst1 inhibition mitigates steroid-induced femoral head osteonecrosis by modulating autophagy in bone microvascular endothelial cells	24
Canonical DDR activation by EMT inducing agent 5-Fluorouracil is modulated by a cannabinoid based combinatorial approach via inducing autophagy and suppression of vimentin expression	24
Enhanced thermogenesis in PAS Kinase-deficient male mice	24
Cardiac human bitter taste receptors contain naturally occurring variants that alter function	24
Ubiquitin ligase TRIM63 regulates HOXA10 expression to mediate fatty acid β-oxidation and suppress lung adenocarcinoma metastasis	24
Harmine suppresses pancreatic cancer through DYRK1A-mediated hyper-activated RAS/MAPK inhibition	24
Corrigendum to “Cardioprotective effects of melatonin and metformin against doxorubicin-induced cardiotoxicity in rats are through preserving mitochondrial function and dynamics” [Biochem. Pharmacol.	24
LncRNA SNHG14 drives angiotensin-induced abdominal aortic aneurysm progression by regulating autophagy via the miR-27b-3p/Wnt/β-catenin/c-Myc axis	24
A systematic review and meta-analysis of environmental contaminant exposure impacts on weight loss and glucose regulation during calorie-restricted diets in preclinical studies: Persistent organic pol	24
Pharmacological inhibition of the MST2/Hippo signaling pathway mitigates Toxoplasma gondii-induced apoptosis and immunopathology in macrophage and mice liver	24
Circ_0057582 inhibits breast cancer progression via hnRNPF/YAP/SOX9 axis and M2 polarization in TAMs by autophagic degradation of ISG15	24
Design and characterization of a triazole-based growth hormone secretagogue receptor modulator inhibiting the glucoregulatory and feeding actions of ghrelin	23
Calcium saccharate/DUSP6 suppresses renal cell carcinoma glycolytic metabolism and boosts sunitinib efficacy via the ERK-AKT pathway	23
Inhibition of soluble epoxide hydrolase relieves adipose inflammation via modulating M1/M2 macrophage polarization to alleviate airway inflammation and hyperresponsiveness in obese asthma	23
Selective activation of cannabinoid receptors by cannabis terpenes	23
Development of 6-methyl-4,5-dihydropyrazolo[3,4-d]pyrimidin-4-one derivatives as lead sigma-1 receptor inhibitor: synthesis and biological evaluation via MSI	23
Curing childhood cancer the “Natural” Way: Nature as the source of chemotherapy agents	23
Delineating the tumour-regulatory roles of EYA4	23
miR-486-5p-rich extracellular vesicles derived from patients with olanzapine-induced insulin resistance negatively affect glucose-regulating function	23
DNMT1 and DNMT3A drive hepatocellular carcinoma progression via epigenetic regulation and are inhibited by 5-azacytidine	23
Carbamazepine disrupts the hypothalamic-pituitary-testicular axis and induces hormonal imbalances and sperm damage through activating GABBR2 to inhibit AC/cAMP/PKA pathway	23
Coffee for the liver: a mechanistic approach	23
Structure-based optimization of Toddacoumalone as highly potent and selective PDE4 inhibitors with anti-inflammatory effects	23
Evaluation of small molecule PD-1/PD-L1 inhibitors in a T cell reporter system	23
Role of long non-coding RNAs in adipose tissue metabolism and associated pathologies	23
Development of an UPLC-MS/MS method for quantification of donafenib and its metabolite in rat plasma: application to drug–drug interaction	23
Oridonin combined with cisplatin synergistically induces apoptosis by activating the NOXA-BCL2 axis in esophageal squamous cell carcinoma	23
Celastrol induces liver cancer cell death via TFEB-mediated lysosome activation and ROS-dependent ferroptosis	23
Enterogastric and enterohepatic recycling of dendrobine in rats: a novel disposition mechanism responsible for pharmacokinetic multiple peaks	23
Metabolic activation of drugs by cytochrome P450 enzymes: Biochemical insights into mechanism-based inactivation by fibroblast growth factor receptor inhibitors and chemical approaches to attenuate re	22
Targeting the DYNLL2-PAK1 axis inhibits caspase-11-dependent pyroptosis to alleviate sepsis	22