Biochemical Pharmacology

Papers
(The median citation count of Biochemical Pharmacology is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
Anti-inflammatory, but not osteoprotective, effect of the TRAF6/CD40 inhibitor 6877002 in rodent models of local and systemic osteolysis364
Drug-oxidizing and conjugating non-cytochrome P450 (non-P450) enzymes in cynomolgus monkeys and common marmosets as preclinical models for humans173
PLK-3-mediated phosphorylation of BAP1 prevents diabetic retinopathy165
Effects of heme oxygenase 1 in the molecular changes and neuropathy associated with type 2 diabetes in mice142
The potent role of Src kinase-regulating glucose metabolism in cancer136
Diabetes and the fabkin complex: A dual-edged sword129
Evidence for the contribution of vasopressin V1B receptors in the pathophysiology of depression117
Corrigendum to “Dose-dependent regulation of mitochondrial function and cell death pathway by sorafenib in liver cancer cells” [Biochem. Pharmacol. 176 (2020) 113902]116
Hydroquinone destabilizes BIM mRNA through upregulation of p62 in chronic myeloid leukemia cells115
A novel L-shaped ortho-quinone analog as PLK1 inhibitor blocks prostate cancer cells in G2 phase109
Editorial Board105
Corrigendum to “Sulfasalazine alleviates neuropathic pain hypersensitivity in mice through inhibition of SGK-1 in the spinal cord” [Biochem. Pharmacol. 185 (2021) 114411]100
An organogold compound impairs Leishmania amazonensis amastigotes survival and delays lesion progression in murine cutaneous leishmaniasis: Mechanistic insights99
Bile acids and bile acid activated receptors in the treatment of Covid-1995
Influence of tumor microenvironment on the different breast cancer subtypes and applied therapies87
Sleep during COVID-19 lockdown: A cross-cultural study investigating job system relevance83
Renoprotective effect of Nesfatin-1 in Adenine-Induced Chronic kidney Disease: An in vitro and in vivo study82
Design, synthesis and anti-tumor activity of novel benzothiophenonaphthalimide derivatives targeting mitochondrial DNA (mtDNA) G-quadruplex82
Inhibition of circular RNA ASPH reduces the proliferation and promotes the apoptosis of hepatic stellate cells in hepatic fibrosis80
ALA-PDT augments intense inflammation in the treatment of acne vulgaris by COX2/TREM1 mediated M1 macrophage polarization78
Provirus reactivation is impaired in HIV-1 infected individuals on treatment with dasatinib and antiretroviral therapy75
ALDH1A1 confers resistance to RAF/MEK inhibitors in melanoma cells by maintaining stemness phenotype and activating PI3K/AKT signaling72
Excess glucocorticoid exposure contributes to adipose tissue fibrosis which involves macrophage interaction with adipose precursor cells69
CircDUSP16 mediates the effect of triple-negative breast cancer in pirarubicin via the miR-1224-3p/TFDP2 axis68
Recent trends in fragment-based anticancer drug design strategies against different targets: A mini-review66
Corrigendum to “Targeting AhR suppresses hepatocyte ferroptosis in MASH by regulating the Pten/Akt/β catenin axis” [Biochem. Pharmacol. 232 (2025) 116711]66
Interplay between the renin angiotensin system and oxidative stress contributes to alcohol addiction by stimulating dopamine accumulation in the mesolimbic pathway65
Identification of a dual JAK3/TEC family kinase inhibitor for atopic dermatitis therapy65
Peptide GLP-1 receptor agonists: From injection to oral delivery strategies64
Methionine cycle in nonalcoholic fatty liver disease and its potential applications63
Roles of microglia in Alzheimer’s disease and impact of new findings on microglial heterogeneity as a target for therapeutic intervention63
LINC00324 promotes cell proliferation and metastasis of esophageal squamous cell carcinoma through sponging miR-493-5p via MAPK signaling pathway62
PXR as the tipping point between innate immune response, microbial infections, and drug metabolism62
Pharmacological inhibition of HDAC6 suppresses NLRP3 inflammasome-mediated IL-1β release61
PGC‐1α activation ameliorates cancer-induced bone pain via inhibiting apoptosis of GABAergic interneurons59
CD73 mitigates hepatic damage in alcoholic steatohepatitis by regulating PI3K/AKT-mediated hepatocyte pyroptosis57
A variety of cytochrome P450 enzymes and flavin-containing monooxygenases in dogs and pigs commonly used as preclinical animal models56
MICAL1 inhibits colorectal cancer cell migration and proliferation by regulating the EGR1/β-catenin signaling pathway55
Exploring tryptophan metabolism: The transition from disturbed balance to diagnostic and therapeutic potential in metabolic diseases55
Decreased HMGB1 expression contributed to cutaneous toxicity caused by lapatinib55
The palladacycle, BTC2, exhibits anti-breast cancer and breast cancer stem cell activity54
Emerging role of m6A modification in fibrotic diseases and its potential therapeutic effect52
The relationship between tumor metabolism and 5-fluorouracil resistance52
Cytochrome P450 2E1 gene knockout or inhibition prevents obesity induced by high-fat diet via regulating energy expenditure52
Neuroanatomical distribution of fluorophores within adult RXFP3 Cre-tdTomato/YFP mouse brain51
Modulation of contextual fear acquisition and extinction by acute and chronic relaxin-3 receptor (RXFP3) activation in the rat retrosplenial cortex49
Alisol A 24-Acetate combats Methicillin-Resistant Staphylococcus aureus infection by targeting the mevalonate biosynthesis49
Luteolin binds Src, promotes STAT3 protein ubiquitination and exerts anti-melanoma effects in cell and mouse models48
Investigation of the role and mechanism of dapagliflozin in mitigating renal injury in rats afflicted with diabetic kidney disease48
Recent advances in studies on FtsZ inhibitors47
CDP-choline modulates cholinergic signaling and gut microbiota to alleviate DSS-induced inflammatory bowel disease47
Translational potential of targeting Anoctamin-1-Encoded Calcium-Activated chloride channels in hypertension47
Evaluation of efficacy- versus affinity-driven agonism with biased GLP-1R ligands P5 and exendin-F147
KDM6B knockdown alleviates sleep deprivation-induced cerebrovascular lesions in APP/PS1 mice by inhibiting PARP16 expression47
Natural product Eriocalyxin B suppressed triple negative breast cancer metastasis both in vitro and in vivo46
Peroxisome proliferator-activated receptor (PPAR) agonists as a potential therapy for inherited metabolic disorders46
Sirtuin1-p53: A potential axis for cancer therapy45
Extracellular adenosine 5′-triphosphate in pulmonary disorders45
Itaconate alleviates β2-microglobulin-induced cognitive impairment by enhancing the hippocampal amino-β-carboxymuconate-semialdehyde-decarboxylase/picolinic acid pathway44
Torachrysone-8-O-β-d-glucoside mediates anti-inflammatory effects by blocking aldose reductase-catalyzed metabolism of lipid peroxidation products44
Single bioengineered ncRNA molecule for dual-targeting toward the control of non-small cell lung cancer patient-derived xenograft tumor growth44
The value of neck adipose tissue as a predictor for metabolic risk in health and type 2 diabetes44
Potential small effector molecules restoring cellular defects due to sialic acid biosynthetic enzyme deficiency: Pathological relevance to GNE myopathy43
Venom composition and bioactive RF-amide peptide toxins of the saddleback caterpillar, Acharia stimulea (Lepidoptera: Limacodidae)43
The short-chain fatty acid acetate modulates orexin/hypocretin neurons: A novel mechanism in gut-brain axis regulation of energy homeostasis and feeding42
Identifying inhibitors of Trypanosoma cruzi nucleoside diphosphate kinase 1 as potential repurposed drugs for Chagas’ disease42
The role and regulation of Pnn in proliferative and non-dividing cells: Form embryogenesis to pathogenesis42
Carbon monoxide in cell signaling and potential therapeutics42
Exploring the glycation association with dyslipidaemia: Novel approach for diabetic nephropathy42
Viral Vectors, Exosomes, and Vexosomes: Potential armamentarium for delivering CRISPR/Cas to cancer cells41
Circadian oscillator NPAS2 regulates diurnal expression and activity of CYP1A2 in mouse liver41
6-O-angeloylplenolin inhibits osteoclastogenesis in vitro via suppressing c-Src/NF-κB/NFATc1 pathways and ameliorates bone resorption in collagen-induced arthritis mouse model40
Dexmedetomidine alleviates anxiety-like behavior in mice following peripheral nerve injury by reducing the hyperactivity of glutamatergic neurons in the anterior cingulate cortex40
Ursolic acid augments the chemosensitivity of drug-resistant breast cancer cells to doxorubicin by AMPK-mediated mitochondrial dysfunction39
Acyclovir resistance in herpes simplex viruses: Prevalence and therapeutic alternatives38
Rosavidin protects against PM2.5-induced lung toxicity via inhibition of NLRP3 inflammasome-mediated pyroptosis by activating the PI3K/AKT pathway38
Tumor Cells-derived exosomal CircRNAs: Novel cancer drivers, molecular mechanisms, and clinical opportunities38
SMURF1 leads to the β-catenin signaling-mediated progression of esophageal squamous carcinoma by losing PATZ1-induced CCNG2 transcription37
FGF2 drives osteosarcoma metastasis through activating FGFR1-4 receptor pathway-mediated ICAM-1 expression37
Melatonin alleviates brain injury in copper-laden rats: Underlying benefits for Wilson’s disease37
SIS3 suppresses osteoclastogenesis and ameliorates bone loss in ovariectomized mice by modulating Nox4-dependent reactive oxygen species37
Targeting non-coding RNAs and N6-methyladenosine modification in hepatocellular carcinoma37
Targeting fuel pocket of cancer cell metabolism: A focus on glutaminolysis37
Knockdown of Galectin-9 alleviates rheumatoid arthritis through suppressing TNF-α-induced activation of fibroblast-like synoviocytes36
Dual-specificity tyrosine phosphorylation-regulated kinase 1A promotes the inclusion of amyloid precursor protein exon 736
Human flavin-containing monooxygenase 1 and its long-sought hydroperoxyflavin intermediate36
Editorial Board36
Immunomodulatory effects of antiangiogenic tyrosine kinase inhibitors in renal cell carcinoma models: Impact on following anti-PD-1 treatments36
Understanding resistance acquisition by Pseudomonas aeruginosa and possible pharmacological approaches in palliating its pathogenesis35
Development of bile acid activated receptors hybrid molecules for the treatment of inflammatory and metabolic disorders35
Effect of pharmacological heart failure drugs and gene therapy on Danon's cardiomyopathy35
GRHL3 drives radiotherapy resistance and blocks the anti-tumor response of NK and CD4+ T cells in lung squamous cell carcinoma via RNF234
Mast cell activation induced by tamoxifen citrate via MRGPRX2 plays a potential adverse role in breast cancer treatment34
Physiological and pharmacological overview of the gonadotropin releasing hormone34
DEC1 deficiency promotes osteoclastic activity by augmenting NFATc1 signaling via transactivation and the Ca2+/calcineurin pathway34
Oleoylethanolamide alleviates hyperlipidaemia-mediated vascular calcification via attenuating mitochondrial DNA stress triggered autophagy-dependent ferroptosis by activating PPARα34
LILRB4 as a novel immunotherapeutic target for multiple diseases34
Epigallocatechin gallate relieves asthmatic symptoms in mice by suppressing HIF-1α/VEGFA-mediated M2 skewing of macrophages34
ALOX5 promotes autophagy-dependent ferroptosis by activating the AMPK/mTOR pathway in melanoma33
Chrysophanol prevents IL-1β-Induced inflammation and ECM degradation in osteoarthritis via the Sirt6/NF-κB and Nrf2/NF-κB axis33
Inhibition of γ-secretase/Notch pathway as a potential therapy for reversing cancer drug resistance33
Uremic toxins activate CREB/ATF1 in endothelial cells related to chronic kidney disease32
Berberine suppresses bladder cancer cell proliferation by inhibiting JAK1-STAT3 signaling via upregulation of miR-17-5p32
Otilonium Bromide acts as a selective USP28 inhibitor and exhibits cytotoxic activity against multiple human cancer cell lines32
Isoflavone glucoside genistin, an inhibitor targeting Sortase A and Listeriolysin O, attenuates the virulence of Listeria monocytogenes in vivo and in vitro32
Macrophage scavenger receptor A1 antagonizes abdominal aortic aneurysm via upregulating IRG132
UGT1A1 dysfunction increases liver burden and aggravates hepatocyte damage caused by long-term bilirubin metabolism disorder32
Treatment with S-adenosylmethionine ameliorates irinotecan-induced intestinal barrier dysfunction and intestinal microbial disorder in mice32
Immunometabolic attributes and mitochondria-associated signaling of Tumor-Associated Macrophages in tumor microenvironment modulate cancer progression32
PPARα/δ dual agonist H11 alleviates diabetic kidney injury by improving the metabolic disorders of tubular epithelial cells31
Role of sirtuins in hepatocellular carcinoma progression and multidrug resistance: Mechanistical and pharmacological perspectives31
Ponatinib exacerbate renal injury in systemic lupus erythematosus mouse model through PDGFR-PI3K/AKT pathway31
Targeting nucleolin by RNA G-quadruplex-forming motif31
BMAL1 plays a crucial role in immune homeostasis during sepsis-induced acute lung injury31
Methyl-oxazolomycin A: A novel oxazolomycin analog with potent selective estrogen receptor degrading activity in breast cancer cells31
Corrigendum to “Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase, in a rodent model of lung injury“ [Biochem. Pharmacol. 63(1) (2002)31
Positive programming of the GC-IGF1 axis mediates adult osteoporosis susceptibility in male offspring rats induced by prenatal dexamethasone exposure31
Brain-immune interactions in neuropsychiatric disorders: Lessons from transcriptome studies for molecular targeting30
Possibility of averting cytokine storm in SARS-COV 2 patients using specialized pro-resolving lipid mediators30
Adenosine kinase: A key regulator of purinergic physiology30
A rational foundation for micheliolide-based combination strategy by targeting redox and metabolic circuit in cancer cells30
CEMIP promotes small cell lung cancer proliferation by activation of glutamine metabolism via FBXW7/c-Myc-dependent axis30
Targeting fibroblast activation protein with chimeric antigen receptor macrophages30
FGFR3 phosphorylates EGFR to promote cisplatin-resistance in ovarian cancer29
Overexpression of retinoid X receptor beta provides protection against oxidized low-density lipoprotein-induced inflammation via regulating PGC1α-dependent mitochondrial homeostasis in endothelial cel29
m6A modification impacts hepatic drug and lipid metabolism properties by regulating carboxylesterase 229
Mitochondrial elongation confers protection against doxorubicin-induced cardiotoxicity29
Overview of the therapeutic strategies for ER positive breast cancer29
Engineering a long acting, non-biased relaxin agonist using Protein-in-Protein technology29
Chronic kidney disease-induced muscle atrophy: Molecular mechanisms and promising therapies28
PCSK9 regulates myofibroblast transformation through the JAK2/STAT3 pathway to regulate fibrosis after myocardial infarction28
SIRT6 regulates endothelium-dependent relaxation by modulating nitric oxide synthase 3 (NOS3)28
Targeting regulated chondrocyte death in osteoarthritis therapy28
MiR-466b-3p/HDAC7 meditates transgenerational inheritance of testicular testosterone synthesis inhibition induced by prenatal dexamethasone exposure28
Role of sodium taurocholate cotransporting polypeptide (NTCP) in HBV-induced hepatitis: Opportunities for developing novel therapeutics28
Differential contribution of renal cytochrome P450 enzymes to kidney endothelial dysfunction and vascular oxidative stress in obesity28
Emerging roles of senolytics/senomorphics in HIV-related co-morbidities28
TNFα blockade reverses vascular and uteroplacental matrix metalloproteinases imbalance and collagen accumulation in hypertensive pregnant rats28
Mithramycin suppresses tumor growth by regulating CD47 and PD-L1 expression27
Structure and function of the highly homologous deubiquitinases ubiquitin specific peptidase 25 and 28: Insights into their pathophysiological and therapeutic roles27
Therapeutic of a white adipose tissue-specific bivalent aptamer in obesity27
Novel DCPIB analogs as dual inhibitors of VRAC/TREK1 channels reduced cGAS-STING mediated interferon responses27
Finding new analgesics: Computational pharmacology faces drug discovery challenges27
Detailed resume of S-methyltransferases: Categories, structures, biological functions and research advancements in related pathophysiology and pharmacotherapy27
IOX-1 suppresses metastasis of osteosarcoma by upregulating histone H3 lysine trimethylation27
Corrigendum to “DOCK2 contributes to endotoxemia-induced acute lung injury in mice by activating proinflammatory macrophages” [Biochem. Pharmacol. 184 (2021) 114399]27
Editorial Board27
Cytarabine-induced destabilization of MCL1 mRNA and protein triggers apoptosis in leukemia cells27
Targeting ectonucleotidases to treat inflammation and halt cancer development in the gut27
Macrophage-derived human resistin promotes perivascular adipose tissue dysfunction in experimental inflammatory arthritis27
Corrigendum to “Geraniol ameliorates acute liver failure induced by lipopolysaccharide/D-galactosamine via regulating macrophage polarization and NLRP3 inflammasome activation by PPAR-γ methylation Ge27
P4HA3 depletion induces ferroptosis and inhibits colorectal cancer growth by stabilizing ACSL4 mRNA26
A review on the effect of COX-2-mediated mechanisms on development and progression of gastric cancer induced by nicotine26
Spectral sensitivity of circadian phase resetting, melatonin suppression and acute alerting effects of intermittent light exposure26
Preclinical evaluation of new drug-drug interactions of lomitapide: A proposal for novel mechanism of interaction associated with lipid metabolic changes26
The critical roles of STING in mitochondrial homeostasis26
Ganoderic acid A exerted antidepressant-like action through FXR modulated NLRP3 inflammasome and synaptic activity26
Mefunidone ameliorates acute liver failure in mice by inhibiting MKK4-JNK pathway26
Maladaptive regeneration and metabolic dysfunction associated steatotic liver disease: Common mechanisms and potential therapeutic targets26
Antibody-drug conjugates for non-small cell lung cancer: Advantages and challenges in clinical translation26
Editorial Board25
Cell-specific drug targeting in the lung25
Eicosatrienoic acid inhibits estradiol synthesis through the CD36/FOXO1/CYP19A1 signaling pathway to improve PCOS in mice25
Corrigendum to “TTI-101: A competitive inhibitor of STAT3 that spares oxidative phosphorylation and reverses mechanical allodynia in mouse models of neuropathic pain” [Biochem. Pharmacol. 192 (2021) 125
Editorial Board25
Structure-based optimization of Toddacoumalone as highly potent and selective PDE4 inhibitors with anti-inflammatory effects25
RNA therapeutics: From biochemical pharmacology to technology development and clinical applications25
Design and characterization of a triazole-based growth hormone secretagogue receptor modulator inhibiting the glucoregulatory and feeding actions of ghrelin25
Activated microglia secretome and proinflammatory cytokines increase neuronal mu-opioid receptor signalling and expression25
Citrulline activates adenosine receptors: New insight into metabolic pathways interaction25
Calcium saccharate/DUSP6 suppresses renal cell carcinoma glycolytic metabolism and boosts sunitinib efficacy via the ERK-AKT pathway25
Is REM sleep a paradoxical state?: Different neurons are activated in the cingulate cortices and the claustrum during wakefulness and paradoxical sleep hypersomnia24
Corrigendum to “Cardioprotective effects of melatonin and metformin against doxorubicin-induced cardiotoxicity in rats are through preserving mitochondrial function and dynamics” [Biochem. Pharmacol. 24
Redox regulation by carotenoids: Evidence and conflicts for their application in cancer24
FXR agonists for colorectal and liver cancers, as a stand-alone or in combination therapy24
Inhibition of soluble epoxide hydrolase relieves adipose inflammation via modulating M1/M2 macrophage polarization to alleviate airway inflammation and hyperresponsiveness in obese asthma24
Azithromycin modulates Teff/Treg balance in retinal inflammation via the mTOR signaling pathway24
Metabolic activation of drugs by cytochrome P450 enzymes: Biochemical insights into mechanism-based inactivation by fibroblast growth factor receptor inhibitors and chemical approaches to attenuate re24
Mechanotransduction and the extracellular matrix: Key drivers of lung pathologies and drug responsiveness24
Metallodrugs: Synthesis, mechanism of action and nanoencapsulation for targeted chemotherapy24
Cardiac human bitter taste receptors contain naturally occurring variants that alter function23
The increasing role of pigment epithelium-derived factor in metastasis: from biological importance to a promising target23
Extracellular nucleotides in smooth muscle contraction23
A systematic review and meta-analysis of environmental contaminant exposure impacts on weight loss and glucose regulation during calorie-restricted diets in preclinical studies: Persistent organic pol23
Neuroactive steroids, WIN-compounds and cholesterol share a common binding site on muscarinic acetylcholine receptors23
Novel pharmacological inhibition of JMJD3 improves necrotizing enterocolitis by attenuating the inflammatory response and ameliorating intestinal injury23
Sterol regulation of developmental and oncogenic Hedgehog signaling23
Polo-like kinase 1 (PLK1) is a novel CARD14-binding protein in keratinocytes23
Discovery of a AHR pelargonidin agonist that counter-regulates Ace2 expression and attenuates ACE2-SARS-CoV-2 interaction23
Resolvin D3 improves the impairment of insulin signaling in skeletal muscle and nonalcoholic fatty liver disease through AMPK/autophagy-associated attenuation of ER stress23
miR-486-5p-rich extracellular vesicles derived from patients with olanzapine-induced insulin resistance negatively affect glucose-regulating function23
An A-ring substituted evodiamine derivative with potent anticancer activity against human non-small cell lung cancer cells by targeting heat shock protein 7023
Curing childhood cancer the “Natural” Way: Nature as the source of chemotherapy agents23
Selpercatinib attenuates bleomycin-induced pulmonary fibrosis by inhibiting the TGF-β1 signaling pathway23
Anticancer potential of novel α,β-unsaturated γ-lactam derivatives targeting the PI3K/AKT signaling pathway23
The relevance of daylight for humans22
Role of long non-coding RNAs in adipose tissue metabolism and associated pathologies22
Pathogenic mitochondrial dysfunction and metabolic abnormalities22
Glucocorticoids and natural killer cells: A suppressive relationship22
Therapeutic targeting of Wnt antagonists by small molecules for treatment of osteoporosis22
Animal models of acute lymphoblastic leukemia: Recapitulating the human disease to evaluate drug efficacy and discover therapeutic targets22
Omega-3 polyunsaturated fatty acids alleviate hyperuricemic nephropathy by inhibiting renal pyroptosis through GPR12022
Quassinoid analogs exert potent antitumor activity via reversible protein biosynthesis inhibition in human colorectal cancer22
3-Hydroxybutyrate ameliorates sepsis-associated acute lung injury by promoting autophagy through the activation of GPR109α in macrophages22
Targeted delivery of a colchicine analogue provides synergy with ATR inhibition in cancer cells22
Cancer stem cells: Recent insights and therapies22
PPARγ activation by fisetin mitigates vascular smooth muscle cell senescence via the mTORC2-FoxO3a-autophagy signaling pathway22
CXCR2, a novel target to overcome tyrosine kinase inhibitor resistance in chronic myelogenous leukemia cells22
AdipoRon and ADP355, adiponectin receptor agonists, in Metabolic-associated Fatty Liver Disease (MAFLD) and Nonalcoholic Steatohepatitis (NASH): A systematic review22
Enhanced thermogenesis in PAS Kinase-deficient male mice22
Delineating the tumour-regulatory roles of EYA422
Integrated metabolomics and transcriptomics reveal the neuroprotective effect of nervonic acid on LPS-induced AD model mice22
The role of taurine through endoplasmic reticulum in physiology and pathology22
Implication of Let7b/AhR/ARNT/HMGB1/RAGE cascade in neuroplasticity disturbances induced by glucocorticoids and the promising reversible effect of 3,3 diindolymethane: Bidirectional crosstalk of Aryl 22
CD146+Mesenchymal stem cells treatment improves vascularization, muscle contraction and VEGF expression, and reduces apoptosis in rat ischemic hind limb22
Discovery of novel carboxylesterase 2 inhibitors for the treatment of delayed diarrhea and ulcerative colitis22
Biology and pharmacology of platelet-type 12-lipoxygenase in platelets, cancer cells, and their crosstalk22
Editorial Board21
Intestinal guard: Human CXCL17 modulates protective response against mycotoxins and CXCL17-mimetic peptides development21
Antiplatelet drug ticagrelor suppresses triple negative breast cancer metastasis by targeting PI3K21
Vesicular monoamine transporter-2 inhibitor JPC-141 prevents methamphetamine-induced dopamine toxicity and blocks methamphetamine self-administration in rats21
Estrogen dampens central cannabinoid receptor 1-mediated neuroexcitation and pressor response in conscious female rats21
AT1 receptors modulate ethanol-induced loss of anticontractile effect of perivascular adipose tissue21
Canonical DDR activation by EMT inducing agent 5-Fluorouracil is modulated by a cannabinoid based combinatorial approach via inducing autophagy and suppression of vimentin expression21
Acknowledgment21
Nicotinamide riboside alleviates brain dysfunction induced by chronic cerebral hypoperfusion via protecting mitochondria21
ASCT2-mediated glutamine uptake promotes Th1 differentiation via ROS-EGR1-PAC1 pathway in oral lichen planus21
Untargeted metabolomics analysis of serum and urine unveils the protective effect of cilastatin on altered metabolic pathways during cisplatin-induced acute kidney injury21
Selective stabilization of the intermediate inactivated Na+ channel by the new-generation anticonvulsant rufinamide21
Editorial Board21
Luxeptinib disables NLRP3 inflammasome-mediated IL-1β release and pathways required for secretion of inflammatory cytokines IL-6 and TNFα21
Sonidegib potentiates the cancer cells’ sensitivity to cytostatic agents by functional inhibition of ABCB1 and ABCG2 in vitro and ex vivo21
Heat shock protein 90 inhibitor 17-AAG down-regulates thymidine phosphorylase expression and potentiates the cytotoxic effect of tamoxifen and erlotinib in human lung squamous carcinoma cells21
Bisphenol-A analogs induce lower urinary tract dysfunction in male mice21
Inhibition of proteasome, but not lysosome, upregulates organic anion transporter 3 in vitro and in vivo21
Inhibition of FABP5 attenuates inflammatory bowel disease by modulating macrophage alternative activation21
Cardiometabolic effects of sacubitril/valsartan in a rat model of heart failure with preserved ejection fraction20
Corrigendum to “Resveratrol inhibits epithelial-mesenchymal transition and renal fibrosis by antagonizing the hedgehog signaling pathway” [Biochem. Pharmacol. 92 (2014) 484–493]20
Corrigendum to “Obesity II: Establishing causal links between chemical exposures and obesity” [Biochem. Pharmacol. 199 (2022) 115015]20
Regulatory roles of CARD9-BCL10-Rac1 (CBR) signalome in islet β-cell function in health and metabolic stress: Is there room for MALT1?20
Editorial Board20
Pharmacological characterization of prostaglandin E2 EP2 and EP4 receptors in male rat locus coeruleus neurons ex vivo20
Corrigendum to “Apoptotic effects of mahanine on human leukemic cells are mediated through crosstalk between Apo-1/Fas signaling and the Bid protein and via mitochondrial pathways” [Biochem. Pharmacol20
A small molecule compound that inhibits blue light-induced retinal damage via activation of autophagy20
The blockade of neddylation alleviates ventilator-induced lung injury by reducing stretch-induced damage to pulmonary epithelial cells20
AMPK activation attenuates HER3 upregulation and Neuregulin-Mediated rescue of cell proliferation in HER2-Overexpressing breast cancer cell lines exposed to lapatinib20
Activation of aryl hydrocarbon receptor by azatyrosine-phenylbutyric hydroxamide inhibits progression of diabetic retinopathy mice20
Detailed functional characterization of four nanobodies as positive allosteric modulators of the human calcium-sensing receptor20
Suppression MGP inhibits tumor proliferation and reverses oxaliplatin resistance in colorectal cancer20
Flavokawain B is an effective natural peroxisome proliferator-activated receptor γ-selective agonist with a strong glucose-lowering effect20
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