Biochemical Pharmacology

Article	Citations
ALKBH7 mediates the mitigative effect of bismuth drug against cisplatin-induced acute kidney injury	264
Editorial Board	220
Corrigendum to “Targeting AhR suppresses hepatocyte ferroptosis in MASH by regulating the Pten/Akt/β catenin axis” [Biochem. Pharmacol. 232 (2025) 116711]	190
Editorial Board	154
CircDUSP16 mediates the effect of triple-negative breast cancer in pirarubicin via the miR-1224-3p/TFDP2 axis	138
Inhibition of circular RNA ASPH reduces the proliferation and promotes the apoptosis of hepatic stellate cells in hepatic fibrosis	132
Effects of heme oxygenase 1 in the molecular changes and neuropathy associated with type 2 diabetes in mice	131
Metformin exhibits inhibitory effects on ferroptosis and alleviates chondrocyte metabolic imbalance in osteoarthritis models, as well as Erastin-induced ferroptosis, through the modulation of the P53/	124
A novel L-shaped ortho-quinone analog as PLK1 inhibitor blocks prostate cancer cells in G2 phase	113
Alisol A 24-Acetate combats Methicillin-Resistant Staphylococcus aureus infection by targeting the mevalonate biosynthesis	112
Unveiling ODP4: A breakthrough in PCOS treatment via BAT transplantation	106
HDAC6 is involved in diabetic nephropathy by regulating TGFβ/Smads and NF-κB signaling pathways	98
AMPK-activation by catecholamines induces autophagy and cell proliferation in cardiac fibroblasts	91
MICAL1 inhibits colorectal cancer cell migration and proliferation by regulating the EGR1/β-catenin signaling pathway	89
Neuroanatomical distribution of fluorophores within adult RXFP3 Cre-tdTomato/YFP mouse brain	86
Modulation of contextual fear acquisition and extinction by acute and chronic relaxin-3 receptor (RXFP3) activation in the rat retrosplenial cortex	82
Anti-inflammatory, but not osteoprotective, effect of the TRAF6/CD40 inhibitor 6877002 in rodent models of local and systemic osteolysis	80
Hydroquinone destabilizes BIM mRNA through upregulation of p62 in chronic myeloid leukemia cells	79
Diabetes and the fabkin complex: A dual-edged sword	78
Corrigendum to “Dose-dependent regulation of mitochondrial function and cell death pathway by sorafenib in liver cancer cells” [Biochem. Pharmacol. 176 (2020) 113902]	78
Identification of a dual JAK3/TEC family kinase inhibitor for atopic dermatitis therapy	76
Interplay between the renin angiotensin system and oxidative stress contributes to alcohol addiction by stimulating dopamine accumulation in the mesolimbic pathway	76
Melatonin protects vascular homeostasis by restoring PVAT redox balance in arterial hypertension	75
PLK-3-mediated phosphorylation of BAP1 prevents diabetic retinopathy	74
Evidence for the contribution of vasopressin V1B receptors in the pathophysiology of depression	72

Butyrolactone I from Aspergillus fungi blocks neutrophil FPR1 to alleviate acute respiratory distress syndrome	71
IP3R-dependent Ca2+ signaling in the endoplasmic reticulum is required for deoxynivalenol-induced intestinal stem cell injury	70
Decreased HMGB1 expression contributed to cutaneous toxicity caused by lapatinib	70
The potent role of Src kinase-regulating glucose metabolism in cancer	65
An organogold compound impairs Leishmania amazonensis amastigotes survival and delays lesion progression in murine cutaneous leishmaniasis: Mechanistic insights	63
Drug-oxidizing and conjugating non-cytochrome P450 (non-P450) enzymes in cynomolgus monkeys and common marmosets as preclinical models for humans	60
Investigation of the role and mechanism of dapagliflozin in mitigating renal injury in rats afflicted with diabetic kidney disease	60
LINC00324 promotes cell proliferation and metastasis of esophageal squamous cell carcinoma through sponging miR-493-5p via MAPK signaling pathway	58
Bromodomain containing protein 4 (BRD4) and cancer therapy: A glimpse at dual-target drug development	57
Indole selectively suppresses aldosterone overproduction via binding to the catalytic site of CYP11B2	57
Methionine cycle in nonalcoholic fatty liver disease and its potential applications	55
Renoprotective effect of Nesfatin-1 in Adenine-Induced Chronic kidney Disease: An in vitro and in vivo study	55
CDP-choline modulates cholinergic signaling and gut microbiota to alleviate DSS-induced inflammatory bowel disease	54
RNA-binding protein GIGYF2 promotes colorectal cancer progression through activation of the METTL3/SERP1/STAT3 axis in an m6A-IGF2BP2-dependent manner	53
SEMA7A orchestrates the colorectal cancer tumor microenvironment via PlexinC1: coordinating angiogenesis and macrophage M2 polarization	53
Peptide GLP-1 receptor agonists: From injection to oral delivery strategies	53
Dual roles of Makorin ring finger protein 1 in ubiquitination and RNA biology: regulatory mechanisms and therapeutic implications in human diseases	52
Ammonium tetrathiomolybdate attenuates acetaminophen-induced acute liver failure by inhibiting the TRPV4/Calcium/NF-κB signaling pathway	51
Restoring mitochondria–endoplasmic reticulum–synapse axis: a proteomic dissection of Rhein’s multi-pathway antidepressant mechanism	50
Histone deacetylase 6 modulates autophagy through HIF-1α/BNIP3 signaling in lung cancer	50
Influence of tumor microenvironment on the different breast cancer subtypes and applied therapies	48
Excess glucocorticoid exposure contributes to adipose tissue fibrosis which involves macrophage interaction with adipose precursor cells	48
ALDH1A1 confers resistance to RAF/MEK inhibitors in melanoma cells by maintaining stemness phenotype and activating PI3K/AKT signaling	48
CD73 mitigates hepatic damage in alcoholic steatohepatitis by regulating PI3K/AKT-mediated hepatocyte pyroptosis	48
A variety of cytochrome P450 enzymes and flavin-containing monooxygenases in dogs and pigs commonly used as preclinical animal models	47
Luteolin binds Src, promotes STAT3 protein ubiquitination and exerts anti-melanoma effects in cell and mouse models	47
Ultraviolet-treated riboflavin alleviates atopic dermatitis by inhibiting NLRP3 inflammasome activation and M1 macrophage polarization via histone lactylation	46
Cytochrome P450 2E1 gene knockout or inhibition prevents obesity induced by high-fat diet via regulating energy expenditure	46
Bile acids and bile acid activated receptors in the treatment of Covid-19	46
ALA-PDT augments intense inflammation in the treatment of acne vulgaris by COX2/TREM1 mediated M1 macrophage polarization	45
Exploring tryptophan metabolism: The transition from disturbed balance to diagnostic and therapeutic potential in metabolic diseases	45
Emerging role of m6A modification in fibrotic diseases and its potential therapeutic effect	45
PXR as the tipping point between innate immune response, microbial infections, and drug metabolism	44
Design, synthesis and anti-tumor activity of novel benzothiophenonaphthalimide derivatives targeting mitochondrial DNA (mtDNA) G-quadruplex	43
The relationship between tumor metabolism and 5-fluorouracil resistance	43
Pharmacological inhibition of HDAC6 suppresses NLRP3 inflammasome-mediated IL-1β release	43
Recent trends in fragment-based anticancer drug design strategies against different targets: A mini-review	42
Editorial Board	41
Serum-derived extracellular vesicles mediate acquired multidrug resistance of MCF-7 breast cancer cells induced by chemotherapeutic drugs	41
PGC‐1α activation ameliorates cancer-induced bone pain via inhibiting apoptosis of GABAergic interneurons	41
Identifying inhibitors of Trypanosoma cruzi nucleoside diphosphate kinase 1 as potential repurposed drugs for Chagas’ disease	41
Potential small effector molecules restoring cellular defects due to sialic acid biosynthetic enzyme deficiency: Pathological relevance to GNE myopathy	40
Editorial Board	40
Mast cell activation induced by tamoxifen citrate via MRGPRX2 plays a potential adverse role in breast cancer treatment	40
PPARα/δ dual agonist H11 alleviates diabetic kidney injury by improving the metabolic disorders of tubular epithelial cells	40
Isoflavone glucoside genistin, an inhibitor targeting Sortase A and Listeriolysin O, attenuates the virulence of Listeria monocytogenes in vivo and in vitro	40
ACE1-targeting peptide Acein ameliorates UV-induced skin damage and aging in vivo and in vitro via downregulation of the pro-aging factor CLEC4G	40
Effect of pharmacological heart failure drugs and gene therapy on Danon's cardiomyopathy	40
Targeting non-coding RNAs and N6-methyladenosine modification in hepatocellular carcinoma	39
Recent advances in studies on FtsZ inhibitors	38

Tumor Cells-derived exosomal CircRNAs: Novel cancer drivers, molecular mechanisms, and clinical opportunities	38
Dexmedetomidine alleviates anxiety-like behavior in mice following peripheral nerve injury by reducing the hyperactivity of glutamatergic neurons in the anterior cingulate cortex	38
Understanding resistance acquisition by Pseudomonas aeruginosa and possible pharmacological approaches in palliating its pathogenesis	38
Treatment with S-adenosylmethionine ameliorates irinotecan-induced intestinal barrier dysfunction and intestinal microbial disorder in mice	38
The value of neck adipose tissue as a predictor for metabolic risk in health and type 2 diabetes	38
Rosavidin protects against PM2.5-induced lung toxicity via inhibition of NLRP3 inflammasome-mediated pyroptosis by activating the PI3K/AKT pathway	38
Exploring the glycation association with dyslipidaemia: Novel approach for diabetic nephropathy	37
Epigallocatechin gallate relieves asthmatic symptoms in mice by suppressing HIF-1α/VEGFA-mediated M2 skewing of macrophages	36
Circadian oscillator NPAS2 regulates diurnal expression and activity of CYP1A2 in mouse liver	36
DEC1 deficiency promotes osteoclastic activity by augmenting NFATc1 signaling via transactivation and the Ca2+/calcineurin pathway	36
Inhibition of γ-secretase/Notch pathway as a potential therapy for reversing cancer drug resistance	36
Torachrysone-8-O-β-d-glucoside mediates anti-inflammatory effects by blocking aldose reductase-catalyzed metabolism of lipid peroxidation products	36
Decoding the roles of CCL11 in human malignancies and clinical implications	35
Activation of the Nrf2/HO-1/GPX4 pathway by cGAMP Mitigates oxidative stress and ferroptosis in ischaemic stroke	35
SMURF1 leads to the β-catenin signaling-mediated progression of esophageal squamous carcinoma by losing PATZ1-induced CCNG2 transcription	35
A modern approach to glioblastoma using temozolomide and nanoparticles carrier drug: a standard care of combination therapy and treatment	35
Itaconate alleviates β2-microglobulin-induced cognitive impairment by enhancing the hippocampal amino-β-carboxymuconate-semialdehyde-decarboxylase/picolinic acid pathway	35
Combining Sorafenib, Se-methylselenocysteine, and α-Ketoacid for synergistic cytotoxicity in Hepatocellular carcinoma cell lines	35
Sonic Hedgehog pathway: molecular mechanisms and therapeutic potentials in ischemic stroke recovery	35
Otilonium Bromide acts as a selective USP28 inhibitor and exhibits cytotoxic activity against multiple human cancer cell lines	35
Macrophage scavenger receptor A1 antagonizes abdominal aortic aneurysm via upregulating IRG1	34
FGF2 drives osteosarcoma metastasis through activating FGFR1-4 receptor pathway-mediated ICAM-1 expression	34
6-O-angeloylplenolin inhibits osteoclastogenesis in vitro via suppressing c-Src/NF-κB/NFATc1 pathways and ameliorates bone resorption in collagen-induced arthritis mouse model	34
Peroxisome proliferator-activated receptor (PPAR) agonists as a potential therapy for inherited metabolic disorders	34
Nodosin alleviates cholestatic liver injury by activation of SIRT1/FXR signaling pathway and inhibition of hepatic inflammation	34
Physiological and pharmacological overview of the gonadotropin releasing hormone	33
Venom composition and bioactive RF-amide peptide toxins of the saddleback caterpillar, Acharia stimulea (Lepidoptera: Limacodidae)	33
Translational potential of targeting Anoctamin-1-Encoded Calcium-Activated chloride channels in hypertension	33
Knockdown of Galectin-9 alleviates rheumatoid arthritis through suppressing TNF-α-induced activation of fibroblast-like synoviocytes	33
KDM6B knockdown alleviates sleep deprivation-induced cerebrovascular lesions in APP/PS1 mice by inhibiting PARP16 expression	33
GRHL3 drives radiotherapy resistance and blocks the anti-tumor response of NK and CD4+ T cells in lung squamous cell carcinoma via RNF2	33
Dual-specificity tyrosine phosphorylation-regulated kinase 1A promotes the inclusion of amyloid precursor protein exon 7	32
Sleep deprivation exacerbates experimental colitis via down-regulating the clock gene Per2	32
Astragaloside IV as a potent vWbp inhibitor: An innovative strategy to mitigate foodborne Staphylococcus aureus infections	32
GPR55: Physiological functions and therapeutic potential in depression	32
Reynoutrin targets EphB4 to ameliorate hepatic glucose and lipid metabolic disorders in type 2 diabetes mellitus	32
The dual targeting effects of KD025 on casein kinase 2 and ROCK2 in a mouse model of diet-induced obesity	32
Melatonin alleviates brain injury in copper-laden rats: Underlying benefits for Wilson’s disease	32
SIS3 suppresses osteoclastogenesis and ameliorates bone loss in ovariectomized mice by modulating Nox4-dependent reactive oxygen species	32
Uremic toxins activate CREB/ATF1 in endothelial cells related to chronic kidney disease	31
The role of metabolic reprogramming in inflammatory bone diseases	31
Chrysophanol prevents IL-1β-Induced inflammation and ECM degradation in osteoarthritis via the Sirt6/NF-κB and Nrf2/NF-κB axis	31
Natural product Eriocalyxin B suppressed triple negative breast cancer metastasis both in vitro and in vivo	31
Carbon monoxide in cell signaling and potential therapeutics	31
ALOX5 promotes autophagy-dependent ferroptosis by activating the AMPK/mTOR pathway in melanoma	31
Viral Vectors, Exosomes, and Vexosomes: Potential armamentarium for delivering CRISPR/Cas to cancer cells	31
Sirtuin1-p53: A potential axis for cancer therapy	31
LILRB4 as a novel immunotherapeutic target for multiple diseases	31
Oleoylethanolamide alleviates hyperlipidaemia-mediated vascular calcification via attenuating mitochondrial DNA stress triggered autophagy-dependent ferroptosis by activating PPARα	30
Acyclovir resistance in herpes simplex viruses: Prevalence and therapeutic alternatives	30
Immunomodulatory effects of antiangiogenic tyrosine kinase inhibitors in renal cell carcinoma models: Impact on following anti-PD-1 treatments	30
Immunometabolic attributes and mitochondria-associated signaling of Tumor-Associated Macrophages in tumor microenvironment modulate cancer progression	30
Ursolic acid augments the chemosensitivity of drug-resistant breast cancer cells to doxorubicin by AMPK-mediated mitochondrial dysfunction	30
Targeting fuel pocket of cancer cell metabolism: A focus on glutaminolysis	30
The short-chain fatty acid acetate modulates orexin/hypocretin neurons: A novel mechanism in gut-brain axis regulation of energy homeostasis and feeding	29
Development of bile acid activated receptors hybrid molecules for the treatment of inflammatory and metabolic disorders	29
Corrigendum to “DOCK2 contributes to endotoxemia-induced acute lung injury in mice by activating proinflammatory macrophages” [Biochem. Pharmacol. 184 (2021) 114399]	29
Mitomycin induced the senescence of alveolar epithelial cells by targeting peroxiredoxin I	29
Maladaptive regeneration and metabolic dysfunction associated steatotic liver disease: Common mechanisms and potential therapeutic targets	29
Corrigendum to “Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase, in a rodent model of lung injury“ [Biochem. Pharmacol. 63(1) (2002)	29
Methyl-oxazolomycin A: A novel oxazolomycin analog with potent selective estrogen receptor degrading activity in breast cancer cells	29
Emerging roles of senolytics/senomorphics in HIV-related co-morbidities	29
A review on the effect of COX-2-mediated mechanisms on development and progression of gastric cancer induced by nicotine	29
Cytarabine-induced destabilization of MCL1 mRNA and protein triggers apoptosis in leukemia cells	28
Detailed resume of S-methyltransferases: Categories, structures, biological functions and research advancements in related pathophysiology and pharmacotherapy	28
Leptin impairs the therapeutic efficacy of adipose-derived mesenchymal stem cells by inducing apoptosis through NLRP3 inflammasomes activation	28
Differential contribution of renal cytochrome P450 enzymes to kidney endothelial dysfunction and vascular oxidative stress in obesity	28
Circadian rhythm disturbance induces osteoarthritis in mice: Involvement of Clock and Bmal1 dysregulation and Pdgfa inhibition	28
Pharmacological inhibition of JNK-MAPK disrupts cigarette smoke-induced RUNX2/Galectin-3 -driven EMT and cancer stemness in lung adenocarcinoma cells	28
Editorial Board	28
Corrigendum to “Geraniol ameliorates acute liver failure induced by lipopolysaccharide/D-galactosamine via regulating macrophage polarization and NLRP3 inflammasome activation by PPAR-γ methylation Ge	28
Ifosfamide alleviates autoimmune toxicity and enhances antitumor efficacy in melanoma immunotherapy	28
Protein prenylation in islet β-cell function in health and metabolic stress	27
Targeting regulated chondrocyte death in osteoarthritis therapy	27
Mithramycin suppresses tumor growth by regulating CD47 and PD-L1 expression	27
Structure and function of the highly homologous deubiquitinases ubiquitin specific peptidase 25 and 28: Insights into their pathophysiological and therapeutic roles	27
Non-covalent mTOR inhibition suppresses NLRP3-GSDMD inflammasome-mediated pyroptosis	27
CEMIP promotes small cell lung cancer proliferation by activation of glutamine metabolism via FBXW7/c-Myc-dependent axis	27
Recent progress in developing ATR inhibitors as anticancer agents	27
Targeting PIM1 ameliorates sepsis-associated acute kidney injury through inhibiting ferroptosis	27

Mefunidone ameliorates acute liver failure in mice by inhibiting MKK4-JNK pathway	27
IOX-1 suppresses metastasis of osteosarcoma by upregulating histone H3 lysine trimethylation	27
xCT/Slc7a11 promotes pulmonary arterial hypertension by disrupting AMPKα suppression of mTOR activation	27
Targeting hematopoietic progenitor kinase 1 (HPK1) for tumor immunotherapy: advances in small molecule inhibitors	26
Ponatinib exacerbate renal injury in systemic lupus erythematosus mouse model through PDGFR-PI3K/AKT pathway	26
PCSK9 regulates myofibroblast transformation through the JAK2/STAT3 pathway to regulate fibrosis after myocardial infarction	26
Positive programming of the GC-IGF1 axis mediates adult osteoporosis susceptibility in male offspring rats induced by prenatal dexamethasone exposure	26
A rational foundation for micheliolide-based combination strategy by targeting redox and metabolic circuit in cancer cells	26
Possibility of averting cytokine storm in SARS-COV 2 patients using specialized pro-resolving lipid mediators	26
Inhibiting Cytosine-Adenine-Guanine (CAG) repeat expansions as a therapeutic strategy for Huntington’s disease	26
Preclinical evaluation of new drug-drug interactions of lomitapide: A proposal for novel mechanism of interaction associated with lipid metabolic changes	26
Novel DCPIB analogs as dual inhibitors of VRAC/TREK1 channels reduced cGAS-STING mediated interferon responses	25
Targeting fibroblast activation protein with chimeric antigen receptor macrophages	25
BMAL1 plays a crucial role in immune homeostasis during sepsis-induced acute lung injury	25
P4HA3 depletion induces ferroptosis and inhibits colorectal cancer growth by stabilizing ACSL4 mRNA	25
SIRT6 regulates endothelium-dependent relaxation by modulating nitric oxide synthase 3 (NOS3)	25
MiR-466b-3p/HDAC7 meditates transgenerational inheritance of testicular testosterone synthesis inhibition induced by prenatal dexamethasone exposure	25
Macrophage-derived human resistin promotes perivascular adipose tissue dysfunction in experimental inflammatory arthritis	25
Overview of the therapeutic strategies for ER positive breast cancer	25
The critical roles of STING in mitochondrial homeostasis	25
A review on tumor-targeting liposomes: Fabrication, mechanism and applications	25
Chronic kidney disease-induced muscle atrophy: Molecular mechanisms and promising therapies	25
Mitochondrial elongation confers protection against doxorubicin-induced cardiotoxicity	25
Rational two-round modification for developing isopeptide bond-containing antimicrobial peptide with enhanced stability and potent activity against multidrug-resistant gram-negative bacteria	25
Role of sodium taurocholate cotransporting polypeptide (NTCP) in HBV-induced hepatitis: Opportunities for developing novel therapeutics	25
Therapeutic of a white adipose tissue-specific bivalent aptamer in obesity	25
Discovery of a novel selective small molecule interleukin-36 receptor antagonist for inflammation and cancer	25
Engineering a long acting, non-biased relaxin agonist using Protein-in-Protein technology	25
Editorial Board	24
miR-486-5p-rich extracellular vesicles derived from patients with olanzapine-induced insulin resistance negatively affect glucose-regulating function	24
Finding new analgesics: Computational pharmacology faces drug discovery challenges	24
Editorial Board	24
Extracellular nucleotides in smooth muscle contraction	24
Piezo1 promotes colitis progression by modulating the Nrf2/NF-κB/NLRP3 signaling pathway	24
Antibody-drug conjugates for non-small cell lung cancer: Advantages and challenges in clinical translation	24
Editorial Board	24
Polo-like kinase 1 (PLK1) is a novel CARD14-binding protein in keratinocytes	24
Corrigendum to “Cardioprotective effects of melatonin and metformin against doxorubicin-induced cardiotoxicity in rats are through preserving mitochondrial function and dynamics” [Biochem. Pharmacol.	24
LncRNA SNHG14 drives angiotensin-induced abdominal aortic aneurysm progression by regulating autophagy via the miR-27b-3p/Wnt/β-catenin/c-Myc axis	24
Role of sirtuins in hepatocellular carcinoma progression and multidrug resistance: Mechanistical and pharmacological perspectives	24
Citrulline activates adenosine receptors: New insight into metabolic pathways interaction	24
Eicosatrienoic acid inhibits estradiol synthesis through the CD36/FOXO1/CYP19A1 signaling pathway to improve PCOS in mice	24
Cardiac human bitter taste receptors contain naturally occurring variants that alter function	23
Harmine suppresses pancreatic cancer through DYRK1A-mediated hyper-activated RAS/MAPK inhibition	23
Inhibition of soluble epoxide hydrolase relieves adipose inflammation via modulating M1/M2 macrophage polarization to alleviate airway inflammation and hyperresponsiveness in obese asthma	23
Structure-based optimization of Toddacoumalone as highly potent and selective PDE4 inhibitors with anti-inflammatory effects	23
Mst1 inhibition mitigates steroid-induced femoral head osteonecrosis by modulating autophagy in bone microvascular endothelial cells	23
Therapeutic targeting of Wnt antagonists by small molecules for treatment of osteoporosis	23
Circ_0057582 inhibits breast cancer progression via hnRNPF/YAP/SOX9 axis and M2 polarization in TAMs by autophagic degradation of ISG15	23
Biology and pharmacology of platelet-type 12-lipoxygenase in platelets, cancer cells, and their crosstalk	23
Enterogastric and enterohepatic recycling of dendrobine in rats: a novel disposition mechanism responsible for pharmacokinetic multiple peaks	23
Curing childhood cancer the “Natural” Way: Nature as the source of chemotherapy agents	23
Targeting TDP-43-activated GRP78/endoplasmic reticulum stress axis suppresses triple-negative breast cancer progression	23
Animal models of acute lymphoblastic leukemia: Recapitulating the human disease to evaluate drug efficacy and discover therapeutic targets	23
Integrated metabolomics and transcriptomics reveal the neuroprotective effect of nervonic acid on LPS-induced AD model mice	23
A novel GSH depletor for simultaneous ferroptosis and cuproptosis Activation in hepatocellular carcinoma	23
Novel pharmacological inhibition of JMJD3 improves necrotizing enterocolitis by attenuating the inflammatory response and ameliorating intestinal injury	23
Enhanced thermogenesis in PAS Kinase-deficient male mice	23
Design and characterization of a triazole-based growth hormone secretagogue receptor modulator inhibiting the glucoregulatory and feeding actions of ghrelin	23
Omega-3 polyunsaturated fatty acids alleviate hyperuricemic nephropathy by inhibiting renal pyroptosis through GPR120	23
Iron supplementation protects against renal ischemia–reperfusion injury by enhancing mitochondrial respiratory complex assembly	23
G-protein coupled receptors in neuroinflammation, neuropharmacology, and therapeutics	23
Calcium saccharate/DUSP6 suppresses renal cell carcinoma glycolytic metabolism and boosts sunitinib efficacy via the ERK-AKT pathway	23
Ubiquitin ligase TRIM63 regulates HOXA10 expression to mediate fatty acid β-oxidation and suppress lung adenocarcinoma metastasis	23
Targeted delivery of a colchicine analogue provides synergy with ATR inhibition in cancer cells	23
FXR agonists for colorectal and liver cancers, as a stand-alone or in combination therapy	22
AdipoRon and ADP355, adiponectin receptor agonists, in Metabolic-associated Fatty Liver Disease (MAFLD) and Nonalcoholic Steatohepatitis (NASH): A systematic review	22
1,2,4-Trimethoxybenzene alleviates cognitive dysfunction in type 2 diabetes model rats by inhibiting NLRP3 inflammasome and restoring gut microbiota disorders	22
Selpercatinib attenuates bleomycin-induced pulmonary fibrosis by inhibiting the TGF-β1 signaling pathway	22
Sterol regulation of developmental and oncogenic Hedgehog signaling	22
Quassinoid analogs exert potent antitumor activity via reversible protein biosynthesis inhibition in human colorectal cancer	22
Novel molecular insights into the role of CRH type 1 receptor in the pathophysiology of depression	22
Canonical DDR activation by EMT inducing agent 5-Fluorouracil is modulated by a cannabinoid based combinatorial approach via inducing autophagy and suppression of vimentin expression	22
Discovery of novel carboxylesterase 2 inhibitors for the treatment of delayed diarrhea and ulcerative colitis	22
Selective activation of cannabinoid receptors by cannabis terpenes	22
Activated microglia secretome and proinflammatory cytokines increase neuronal mu-opioid receptor signalling and expression	22
5-O-Methylvisammioside, a novel inhibitor of CNT2, improves hyperuricemia by inhibiting intestinal purine nucleoside absorption with a safe profile	22
Coffee for the liver: a mechanistic approach	22
Triflupromazine and tranylcypromine alleviate primary cisplatin resistance in lung adenocarcinoma by promoting LDHA-mediated AMBRA1 ubiquitination	22
Corrigendum to “TTI-101: A competitive inhibitor of STAT3 that spares oxidative phosphorylation and reverses mechanical allodynia in mouse models of neuropathic pain” [Biochem. Pharmacol. 192 (2021) 1	22
Anti-inflammatory mechanism of the MLKL inhibitor necrosulfonamide in LPS- or poly(I:C)-induced neuroinflammation and necroptosis	22
Resolvin D3 improves the impairment of insulin signaling in skeletal muscle and nonalcoholic fatty liver disease through AMPK/autophagy-associated attenuation of ER stress	22
Development of an UPLC-MS/MS method for quantification of donafenib and its metabolite in rat plasma: application to drug–drug interaction	22
Metabolic activation of drugs by cytochrome P450 enzymes: Biochemical insights into mechanism-based inactivation by fibroblast growth factor receptor inhibitors and chemical approaches to attenuate re	22
AMPK activation attenuates HER3 upregulation and Neuregulin-Mediated rescue of cell proliferation in HER2-Overexpressing breast cancer cell lines exposed to lapatinib	21
Estrogen dampens central cannabinoid receptor 1-mediated neuroexcitation and pressor response in conscious female rats	21
Corrigendum to “Obesity II: Establishing causal links between chemical exposures and obesity” [Biochem. Pharmacol. 199 (2022) 115015]	21
Vesicular monoamine transporter-2 inhibitor JPC-141 prevents methamphetamine-induced dopamine toxicity and blocks methamphetamine self-administration in rats	21
Activation of aryl hydrocarbon receptor by azatyrosine-phenylbutyric hydroxamide inhibits progression of diabetic retinopathy mice	21
A high affinity Sybody blocks Cofilin-1 binding to F-actin in vitro and in cancer cells	21
The blockade of neddylation alleviates ventilator-induced lung injury by reducing stretch-induced damage to pulmonary epithelial cells	21
DNA methylation as an oncogenic driver in breast cancer: Therapeutic targeting via epigenetic reprogramming of DNA methyltransferases	21
Relaxin as a treatment for musculoskeletal fibrosis: What we know and future directions	21
Potential role of modulating autophagy levels in sensorineural hearing loss	21
PPARγ activation by fisetin mitigates vascular smooth muscle cell senescence via the mTORC2-FoxO3a-autophagy signaling pathway	21