OOIR: Observatory of International Research

Papers

(The H4-Index of Biochemical Pharmacology is 49. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Corrigendum to “Dose-dependent regulation of mitochondrial function and cell death pathway by sorafenib in liver cancer cells” [Biochem. Pharmacol. 176 (2020) 113902]	219
Hydroquinone destabilizes BIM mRNA through upregulation of p62 in chronic myeloid leukemia cells	193
A novel L-shaped ortho-quinone analog as PLK1 inhibitor blocks prostate cancer cells in G2 phase	163
Editorial Board	162
Inhibition of circular RNA ASPH reduces the proliferation and promotes the apoptosis of hepatic stellate cells in hepatic fibrosis	155
CircDUSP16 mediates the effect of triple-negative breast cancer in pirarubicin via the miR-1224-3p/TFDP2 axis	139
The potent role of Src kinase-regulating glucose metabolism in cancer	135
Identification of a dual JAK3/TEC family kinase inhibitor for atopic dermatitis therapy	127
Evidence for the contribution of vasopressin V1B receptors in the pathophysiology of depression	126
LINC00324 promotes cell proliferation and metastasis of esophageal squamous cell carcinoma through sponging miR-493-5p via MAPK signaling pathway	121
Neuroanatomical distribution of fluorophores within adult RXFP3 Cre-tdTomato/YFP mouse brain	119
Modulation of contextual fear acquisition and extinction by acute and chronic relaxin-3 receptor (RXFP3) activation in the rat retrosplenial cortex	114
Alisol A 24-Acetate combats Methicillin-Resistant Staphylococcus aureus infection by targeting the mevalonate biosynthesis	105
Anti-inflammatory, but not osteoprotective, effect of the TRAF6/CD40 inhibitor 6877002 in rodent models of local and systemic osteolysis	100
PLK-3-mediated phosphorylation of BAP1 prevents diabetic retinopathy	98
Effects of heme oxygenase 1 in the molecular changes and neuropathy associated with type 2 diabetes in mice	97
Metformin exhibits inhibitory effects on ferroptosis and alleviates chondrocyte metabolic imbalance in osteoarthritis models, as well as Erastin-induced ferroptosis, through the modulation of the P53/	93
Diabetes and the fabkin complex: A dual-edged sword	92
Luteolin binds Src, promotes STAT3 protein ubiquitination and exerts anti-melanoma effects in cell and mouse models	91
An organogold compound impairs Leishmania amazonensis amastigotes survival and delays lesion progression in murine cutaneous leishmaniasis: Mechanistic insights	80
Excess glucocorticoid exposure contributes to adipose tissue fibrosis which involves macrophage interaction with adipose precursor cells	75
MICAL1 inhibits colorectal cancer cell migration and proliferation by regulating the EGR1/β-catenin signaling pathway	74
Exploring tryptophan metabolism: The transition from disturbed balance to diagnostic and therapeutic potential in metabolic diseases	74
Unveiling ODP4: A breakthrough in PCOS treatment via BAT transplantation	72
Bile acids and bile acid activated receptors in the treatment of Covid-19	71

Design, synthesis and anti-tumor activity of novel benzothiophenonaphthalimide derivatives targeting mitochondrial DNA (mtDNA) G-quadruplex	70
Provirus reactivation is impaired in HIV-1 infected individuals on treatment with dasatinib and antiretroviral therapy	70
Renoprotective effect of Nesfatin-1 in Adenine-Induced Chronic kidney Disease: An in vitro and in vivo study	69
Sleep during COVID-19 lockdown: A cross-cultural study investigating job system relevance	68
Peptide GLP-1 receptor agonists: From injection to oral delivery strategies	68
Ultraviolet-treated riboflavin alleviates atopic dermatitis by inhibiting NLRP3 inflammasome activation and M1 macrophage polarization via histone lactylation	68
PGC‐1α activation ameliorates cancer-induced bone pain via inhibiting apoptosis of GABAergic interneurons	67
Methionine cycle in nonalcoholic fatty liver disease and its potential applications	63
Cytochrome P450 2E1 gene knockout or inhibition prevents obesity induced by high-fat diet via regulating energy expenditure	63
Editorial Board	62
ALKBH7 mediates the mitigative effect of bismuth drug against cisplatin-induced acute kidney injury	61
AMPK-activation by catecholamines induces autophagy and cell proliferation in cardiac fibroblasts	61
HDAC6 is involved in diabetic nephropathy by regulating TGFβ/Smads and NF-κB signaling pathways	59
Corrigendum to “Targeting AhR suppresses hepatocyte ferroptosis in MASH by regulating the Pten/Akt/β catenin axis” [Biochem. Pharmacol. 232 (2025) 116711]	57
CD73 mitigates hepatic damage in alcoholic steatohepatitis by regulating PI3K/AKT-mediated hepatocyte pyroptosis	56
CDP-choline modulates cholinergic signaling and gut microbiota to alleviate DSS-induced inflammatory bowel disease	55
A variety of cytochrome P450 enzymes and flavin-containing monooxygenases in dogs and pigs commonly used as preclinical animal models	54
PXR as the tipping point between innate immune response, microbial infections, and drug metabolism	53
Investigation of the role and mechanism of dapagliflozin in mitigating renal injury in rats afflicted with diabetic kidney disease	53
Recent trends in fragment-based anticancer drug design strategies against different targets: A mini-review	51
Decreased HMGB1 expression contributed to cutaneous toxicity caused by lapatinib	51
Influence of tumor microenvironment on the different breast cancer subtypes and applied therapies	51
Ammonium tetrathiomolybdate attenuates acetaminophen-induced acute liver failure by inhibiting the TRPV4/Calcium/NF-κB signaling pathway	50
Pharmacological inhibition of HDAC6 suppresses NLRP3 inflammasome-mediated IL-1β release	50
Roles of microglia in Alzheimer’s disease and impact of new findings on microglial heterogeneity as a target for therapeutic intervention	49