Annals of Clinical Biochemistry

Article	Citations
Best practice in statistics: The use of log transformation	73
Best practice in statistics: Use the Welch t-test when testing the difference between two groups	56
Elevated procalcitonin concentrations in severe Covid-19 may not reflect bacterial co-infection	39
Development of a high-throughput SARS-CoV-2 antibody testing pathway using dried blood spot specimens	32
Correlating arterial blood gas, acid–base and blood pressure abnormalities with outcomes in COVID-19 intensive care patients	32
Monocyte distribution width as a biomarker of sepsis in the intensive care unit: A pilot study	29
Serum biomarkers for prediction of mortality in patients with COVID-19	23
Identifying mislabelled samples: Machine learning models exceed human performance	18
Evaluation of the usability of various rapid antibody tests in the diagnostic application for COVID-19	17
Clinical adoption of Nephrocheck® in the early detection of acute kidney injury	17
Faecal haemoglobin concentration thresholds for reassurance and urgent investigation for colorectal cancer based on a faecal immunochemical test in symptomatic patients in primary care	17
Performance verification of anti-SARS-CoV-2-specific antibody detection by using four chemiluminescence immunoassay systems	16
Method-dependent variation in TSH and FT4 reference intervals in pregnancy: A systematic review	16
The use of whole blood capillary samples to measure 15 analytes for a home-collect biochemistry service during the SARS-CoV-2 pandemic: A proposed model from North West London Pathology	15
An LC-MS/MS assay for analysis of equilibrium angiotensin II in human serum	13
Reference values for C-reactive protein and procalcitonin at term pregnancy and in the early postnatal period	13
Plasma miR-193a-3p can be a potential biomarker for the diagnosis of diabetic nephropathy	13
Negative interference from immunoglobulin M paraproteinaemia on the Roche enzymatic creatinine method	10
Clinical and laboratory aspects of 3,3′,5′-triiodothyronine (reverse T3)	10
Machine learning predictive models of LDL-C in the population of eastern India and its comparison with directly measured and calculated LDL-C	10
Calculated globulin as a screening tool for hypogammaglobulinaemia or paraproteins in hospitalized patients	9
Drug dosing using estimated glomerular filtration rate: Misclassification due to metamizole interference in a creatinine assay	8
Co-analysis of pancreatic cyst fluid carcinoembryonic antigen and glucose with novel cut-off levels better distinguishes between mucinous and non-mucinous neoplastic pancreatic cystic lesions	8
Tumour markers in prostate cancer: The post-prostate-specific antigen era	8
Assessing bone formation in patients with chronic kidney disease using procollagen type I N-terminal propeptide (PINP): The choice of assay makes a difference	8

Reflex and reflective testing: progress, but much still to be done	7
Replicate and repeat faecal immunochemical tests in symptomatic patients: A systematic review	7
Clinical laboratory medicine measurements correlation analysis under uncertainty	7
Can artificial intelligence replace biochemists? A study comparing interpretation of thyroid function test results by ChatGPT and Google Bard to practising biochemists	7
The use of routine blood tests to assist the diagnosis of COVID-19 in symptomatic hospitalized patients	7
Biological sources of variations of tartrate-resistant acid phosphatase 5b in a healthy Japanese population	7
Comparison of high-sensitivity C-reactive protein vs. C-reactive protein for diagnostic accuracy and prediction of mortality in patients with acute myocardial infarction	6
The association between acid–base status and clinical outcome in critically ill COVID-19 patients admitted to intensive care unit with an emphasis on high anion gap metabolic acidosis	6
Expected values for gastrointestinal and pancreatic hormone concentrations in healthy volunteers in the fasting and postprandial state	6
Performance characteristics of five SARS-CoV-2 serological assays: Clinical utility in health-care workers	6
SARS-CoV-2 (Covid-19): A short update on molecular biochemistry, pathology, diagnosis and therapeutic strategies	6
SARS-CoV-2 immunochromatographic IgM/IgG rapid test in pregnancy: A false friend?	6
Comparison of ultra-performance liquid chromatography and ARK immunoassay for therapeutic drug monitoring of voriconazole	6
Development, validation, and application of an UPLC-MS/MS method for vancomycin, norvancomycin, methotrexate, paclitaxel, and imatinib analysis in human plasma	6
Pneumatic tube validation: Reducing the need for donor samples by integrating a vial-embedded data logger	6
The effect of haemolysis on the direct and indirect ion selective electrode measurement of sodium	5
Performance of commercially-available cholesterol self-tests	5
Case report: Interference from isatuximab on serum protein electrophoresis prevented demonstration of complete remission in a myeloma patient	5
A rapid LC-MS/MS assay for the measurement of serum methotrexate in patients who have received high doses for chemotherapy	5
Management of transgender patients in Laboratory Information Management Systems – Moving on from binary and ternary logic	5
Conflicting effects of haemolysis on plasma sodium and chloride are due to different haemolysis study protocols: A case for standardisation	4
Effects of bilirubin configurational photoisomers on the measurement of direct bilirubin by the vanadate oxidation method	4
Analytical characterization and clinical performance evaluation of a new point-of-care testing system for high-sensitivity cardiac troponin I assay	4
Do faecal test-based colorectal cancer screening pilots provide data that are reflected in subsequent programmes? Evidence from interval cancer proportions	4
Application of the sigma metrics to evaluate the analytical performance of cystatin C and design a quality control strategy	4
Alternative diagnoses and demographics associated with a raised quantitative faecal immunochemical test in symptomatic patients	4
Trimester-specific reference intervals for cystatin C and neutrophil gelatinase-associated lipocalin during pregnancy	4
Reference intervals of urinary kidney injury biomarkers for middle-aged men and women determined by quantitative protein mass spectrometry	4
Assessment of the analytical performance of point-of-care faecal immunochemical tests for haemoglobin	4
Survey of patient perception of pre-analytical requirements for blood testing in the UK and RoI	4
Multiple biomarkers measurement to estimate the duration of atrial fibrillation	4
Does the use of fish oil-based lipid emulsion in the clinical setting of total parenteral nutrition and lipid rescue therapy interfere with common laboratory analytes on Roche Cobas 6000?	4
Factors influencing the derivation and clinical application of blood calcium adjustment equations	4
Variation of eGFR reporting and CKD equations used in the United Kingdom	3
Can patients with mild post-operative hyponatraemia following elective arthroplasty be discharged safely? A large-scale service evaluation suggests they can	3
Novel cholesterol efflux assay using immobilized liposome-bound gel beads: Confirmation and improvement for application in clinical laboratory	3
Standardising the biochemical confirmation of adult male hypogonadism; a joint position statement by the Society for Endocrinology and Association of Clinical Biochemistry and Laboratory Medicine*	3
Falsely elevated thyroid hormone levels associated with fibrin interference in patients receiving oral anticoagulant therapy	3
A standard addition method to quantify serum lithium by inductively coupled plasma mass spectrometry	3
Lithium heparin interference in the Abbott enzymatic creatinine assay: the significance of under-filled tubes	3
National recommendations to standardise acute kidney injury detection and alerting	3
“Macro transcobalamin causing raised vitamin B12: Case-based laboratory investigation"	3
Repeat measurements on patient samples identifies unpredictable and poorly reproducible cardiac troponin results with a high-sensitivity cardiac troponin assay	3
MicroRNA in the diagnosis of lung cancer: An overview of ten systematic reviews	3
Correlation of serum myonectin concentrations with the presence and severity of obstructive sleep apnoea syndrome	3
Personalising laboratory medicine in the ‘real world’: Assessing clinical utility, by clinical indication, of serum total B12 and Active-B12® (holotranscobalamin) in the diagnosi	3
Determination of a Beckman Coulter AU turbidometric method-specific caeruloplasmin reference interval	3
Diagnostic performance of serum calprotectin in discriminating active from inactive ulcerative colitis in an outpatient setting	3
Serum cortisol assay performance following the 1 mg overnight dexamethasone suppression test	3
Predicting ionized hypocalcemia: External validation of an ionized calcium prediction model in patients with COVID-19 and renal failure	3

Time-resolved fluorescence immunoassay for urine retinol-binding protein is more sensitive than polyclonal and monoclonal assays	3
UK National audit of the measurement of ammonia	3
Reference intervals for clinical biochemistry and haematology tests during normal pregnancy	3
Establishment of reference intervals for plasma metanephrines in seated position measured by LC-MS/MS and assessment of diagnostic performance in pheochromocytoma/paraganglioma	3
Key methodological challenges in detecting circulating miRNAs in different biofluids	3
Implementing cardiovascular precision diagnostics: laboratory specialists as catalysts?	3
Routine use of natriuretic peptides: Lessons from a big data analysis	3
Closed analyser lids do not reduce the measurement uncertainty of serum total carbon dioxide	2
Vitamin D testing: Impact of changes to testing guidelines on detection of patients at risk of vitamin D deficiency	2
Hepcidin analysis in pneumonia: Comparison of immunoassay and LC-MS/MS	2
Quality control of total carbon dioxide (CO2) in serum or plasma using the Abbott Architect is affected by environmental pCO2 concentrations	2
Serum carbohydrate antigen 72-4 concentrations decrease with age in females but not in males in Beijing, China	2
Fibrin monomer complex as a potential thrombosis marker related to venous thromboembolism risk in pregnant women	2
The clinical and laboratory impact of reporting faecal elastase-1 in watery stool samples	2
Investigating the effects of endogenous lipaemia on the measurement of sodium by indirect ion specific electrode potentiometry	2
Reference intervals for biochemical analytes in transgender individuals on hormone therapy	2
The effectiveness of an automated algorithm as a tool for investigating the cause of anaemia in undiagnosed patients from general practitioners	2
Artefactually low creatinine by Beckman Coulter enzymatic method due to immunoglobulin M paraprotein interference	2
Reducing neonatal phlebotomy blood losses through the accurate calculation of minimum test volume requirements	2
An observational study of replicate faecal immunochemical tests in the urgently referred symptomatic cohort	2
Interferences in immunoassay: An estimate based on ‘real-world’ experience	2
Evaluation of the MP Rapid 2019-NCOV IgM/IgG combo POCT test vs. an established platform-based method	2
Reference intervals for thyroid-stimulating hormone, free thyroxine, free triiodothyronine, and total triiodothyronine in the Lebanese adult population	2
A comparison of two LC-MS/MS methods and one radioimmunoassay for the analysis of salivary melatonin	2
Monitoring motherhood: Monitoring and optimizing glycaemia in women with pre-existing diabetes in pregnancy	2
LC-MS/MS the First 20 years: A Personal View	2
Reducing the number of unnecessary laboratory tests within hospital through the use of educational interventions	2
Cross-sectional audit assessing the quality of dried bloodspot specimens received by UK metabolic biochemistry laboratories for the biochemical monitoring of individuals with Phenylketonuria	2
Analytical method comparisons do not consider the comparison of reference ranges which may lead to differences in diagnosis and patient management: A case for clinical discordance checks	2
Removal of ethnicity adjustment for creatinine-based estimated glomerular filtration rate equations	2
Explainability does not improve biochemistry staff trust in artificial intelligence-based decision support	2
Reference interval for serum concentration of small dense low-density lipoprotein cholesterol in the healthy Japanese population	2
Are point-of-care urine drug testing devices suitable for antenatal drug screening? A study verifying the Alere® Drug Screen Test Cup for the detection of six classes of drug in a pregnant population	2
Measurement of vitamin D in dried blood spots stored under different temperature conditions	2
Practical approaches to the detection of macrotroponin	2
Faecal haemoglobin examinations have come of age, but further maturation seems desirable	2
Use of faecal immunochemical testing as an alternative to faecal calprotectin in children	2
Clinical and molecular findings in children and young adults with persistent low alkaline phosphatase concentrations	2
Prognostic significance of serum alkaline phosphatase for all-cause mortality in patients with hypertrophic cardiomyopathy: A cohort of the hospitalized population	2
A survey of the reactivity of in vitro diagnostic bilirubin reagents developed in Japan using artificially prepared bilirubin materials: A comparison of synthetic delta, unconjugated, and tauri	2
A UK national audit of the laboratory investigation of phaeochromocytoma and paraganglioma	2
Biochip array technology for new psychoactive substances detection in biological samples: Evaluation of the specificity of the Randox Evidence Investigator®	2
Establishment of trimester-specific reference intervals for thyroid stimulating hormone and free thyroxine during pregnancy in southwest China by indirect method	2
Faecal haemoglobin concentration in adenoma, before and after polypectomy, approaches the ideal tumour marker	2
Assessing the cardiotoxicity of Epirubicin-based chemotherapy in patients with breast cancer using high-sensitivity cardiac troponin T, N-terminal pro b-type natriuretic peptide and soluble suppressio	2
The effect of paraprotein polymerisation on quantitation by capillary zone electrophoresis and Hevylite®	2
Assessment of humoral responses in COVID-19 using various quantitative antibody tests	2
Pregnancy-specific reference intervals: should we exclude women based on body mass index?	2
Validation of the Martin method to estimate low-density lipoprotein cholesterol concentrations in Japanese populations and a modified method for laboratory information system application	2
Plasma clearance and lipaemic index of lipid emulsion used for lipid emulsion treatment	2
Reportable range of quantitative assays for SARS-CoV-2 antibodies determination: An overlooked issue?	1
A survey of practice in the management of haemolysis, icterus and lipaemia in blood specimens in the United Kingdom and Republic of Ireland	1
The role of the laboratory in the diagnosis of an unusual case of Waldenstrom’s macroglobulinaemia that lacked the common clinical features: A case report	1
Concordance in COVID-19 serology, bone mineralization, and inflammatory analytes between venous and self-collected capillary blood samples exposed to various pre-analytical conditions	1
Different serum sodium assay, different model for end stage liver disease - sodium scores in patients awaiting liver transplant: A cross-sectional study	1
Developing and validating a highly sensitive platelet clump detection model for the Sysmex haematology analyser	1
Adjustment of calcium and Pathology Harmony	1
Samples spiked with pituitary-derived thyroid-stimulating hormone may disguise the extent of differences between thyroid-stimulating hormone assays	1
Comparison of faecal calprotectin using two collection and extraction strategies for the BÜHLMANN CALEX® Cap – possible implications for clinical cut-offs?	1
Preliminary evaluation of the diagnostic performance of Roche Elecsys® active vitamin B12 versus total vitamin B12 for vitamin B12 deficiency screening	1
Rapid diagnostic strategies using high sensitivity troponin assays: what is the evidence and how should they be implemented?	1
Finding the broken helix: The mainstreaming of genomic medicine into clinical biochemistry	1
A service evaluation of the use of faecal immunochemical tests in symptomatic patients aged under 50 years presenting to primary care	1
The laboratory investigation of pleural fluids: An update based on the available evidence	1
Age- and sex-related reference interval for free thyroxine: An indirect approach	1
Age-specific reference intervals of serum anti-Müllerian hormone in Chinese girls	1
Recent developments in the measurement and application of small dense LDL-cholesterol	1
Dataset dependency of low-density lipoprotein-cholesterol estimation by machine learning	1
Vascular endothelial growth factor (VEGF)-A and VEGF-A165b are associated with time to remission of granulomatosis with polyangiitis in a nationwide Japanese prospective cohort study	1
The preservation of synovial fluid using dimethyl sulfoxide	1
Serum human epididymis secretory protein 4 correlates with sepsis-associated acute respiratory distress syndrome and 28-day mortality in critically ill patients	1
Prevalence of paraprotein interference in three clinical chemistry analytes in a routine biochemistry laboratory	1
A composite risk model predicts disease progression in early stages of COVID-19: A propensity score-matched cohort study	1
Stability of Anti-thyroid Stimulating Hormone Receptor Antibody in Whole Blood and Serum: Caution Required for Reflective and Batch Testing	1
Determination and verification of reference intervals of serum immunoglobulin G at birth	1
Establishment of risk quality control charts based on risk management strategies	1
Is plasma concentration of coenzyme Q10 a predictive marker for left ventricular remodelling after revascularization for ST-segment elevation myocardial infarction?	1
Analytical validation of eight methods of thyroglobulin measurement in fine-needle aspiration washouts	1
Artificially raised creatinine concentrations due to analytical interference for samples contaminated with total parenteral nutrition fluid	1
Isoelectric focusing followed by affinity immunoblotting to detect monoclonal free light chains in monoclonal gammopathies: Comparison with immunofixation electrophoresis and free light chain ratio	1

Stability assessment of serum tumour markers: Calcitonin, chromogranin A, thyroglobulin and anti-thyroglobulin antibodies	1
Plasma cell-free DNA in patients with acute promyelocytic leukaemia treated with arsenic trioxide	1
Calculated small dense LDL-cholesterol and its correlation with the atherogenic index of plasma	1
Determination of in vitro stability of routine haematinics tests using EFLM standards and the CRESS checklist	1
Use of eGFR instead of creatinine in exclusion criteria for derivation of calcium adjustment equation	1
Stability of maternal serum free β-hCG following whole blood sample transit: First trimester Down’s syndrome screening in Scotland	1
Example of use of clock time-dependent targets for patient-based quality control	1
Testing for lactase non-persistence in a Dutch population: Genotyping versus the hydrogen breath test	1
Clinical performance of the Elecsys® anti-SARS-CoV-2 combined in an algorithm with two specific anti-IgG immunoassays for the evaluation of the serological response of patients with COVID-19 in a pop	1
‘A case of autoimmune hepatitis associated with the PCSK9 inhibitor alirocumab’	1
Verification of the Bühlmann fPELA turbo faecal elastase assay on the Binding Site Optilite benchtop analyser	1
Current practice and recommendations for managing transgender patient data in clinical laboratories in the United Kingdom and Republic of Ireland	1
Maintaining glucose integrity ex-vivo: Impact of preanalytical specimen handling	1
Comparison of two primer-probe sets of Fusobacterium nucleatum using droplet digital polymerase chain reaction for the detection of colorectal neoplasia from faecal samples	1
Turnaround times and modes of reporting critical results in Asian laboratories	1
Porphyria cutanea tarda precipitated by ovarian stimulation during oocyte retrieval in a genetically susceptible female	1
Covid-19 and hypokalaemia – A potential mechanism	1
Evaluation of the two-point calibration bromocresol green method, showing reduced deviation from the bromocresol purple method in sera from patients with hypoalbuminemia	1
EQA: There’s not a glitch in the matrix. Investigation of CRP bias on the Roche Cobas c701	1
An easy, fast, and efficient assay for the quantification of peptide Hepcidin-25 in serum and plasma with LC-MS/MS.	1
Air contamination of therapeutic drug monitoring assay reagents results in falsely high plasma ammonia levels	1
Cardiac troponin in hospitalized COVID-19 patients: Incidence, predictors, and outcomes	1
Comparison of four high-throughput, automated immunoassays for the detection of SARS-CoV-2 antibodies	1
Health economic evaluations of medical tests: Translating laboratory information into value – A case study example	1
Does visually over-loaded HM-JACKarc collection device impact faecal haemoglobin results?	1
Validation of the Randox colorimetric assays for serum copper and zinc	1
Serum GP88 as a predictive biomarker for hepatocellular carcinoma in patients with viral hepatitis C after direct-acting antiviral agents	1
Managing ethylenediaminetetraacetic acid (EDTA) interference in EDTA contaminated samples – selectivity in reporting analytes	1
A rare case of persistent hyperkalaemia	1