Analytical Biochemistry

Article	Citations
Lateral flow assay using aptamer-based sensing for on-site detection of dopamine in urine	74
Biosensor-based diagnostic approaches for various cellular biomarkers of breast cancer: A comprehensive review	68
Determination of carcinoembryonic antigen as a tumor marker using a novel graphene-based label-free electrochemical immunosensor	61
Innovation in the food industry using microbial transglutaminase: Keys to success and future prospects	61
A low-cost paper-based aptasensor for simultaneous trace-level monitoring of mercury (II) and silver (I) ions	50
Optimization of serine phosphorylation prediction in proteins by comparing human engineered features and deep representations	50
Optimization and application of MTT assay in determining density of suspension cells	49
Advances of aptamers screened by Cell-SELEX in selection procedure, cancer diagnostics and therapeutics	49
Various types of electrochemical biosensors for leukemia detection and therapeutic approaches	48
Radical-based photoinactivation of fatty acid photodecarboxylases	48
Prediction of protein crotonylation sites through LightGBM classifier based on SMOTE and elastic net	48
Protein quantification by bicinchoninic acid (BCA) assay follows complex kinetics and can be performed at short incubation times	43
Recent advances in FRET-Based biosensors for biomedical applications	42
Molecularly imprinted polymers-based DNA biosensors	41
Recent progress in transglutaminase-mediated assembly of antibody-drug conjugates	40
iTTCA-Hybrid: Improved and robust identification of tumor T cell antigens by utilizing hybrid feature representation	39
Development of a lateral flow aptamer assay strip for facile identification of theranostic exosomes isolated from human lung carcinoma cells	38
Biomolecular condensates in cell biology and virology: Phase-separated membraneless organelles (MLOs)	37
Ultrasensitive aptamer-functionalized Cu-MOF fluorescent nanozyme as an optical biosensor for detection of C-reactive protein	37
Non-enzymatic glucose sensor based on a g-C3N4/NiO/CuO nanocomposite	37
Dual Aptamer-DNAzyme based colorimetric assay for the detection of AFB1 from food and environmental samples	35
Green synthesis of silver nanoparticles using pollen extract: Characterization, assessment of their electrochemical and antioxidant activities	35
Electrochemical immunosensor based on self-assembled gold nanorods for label-free and sensitive determination of Staphylococcus aureus	34
A suspension-based assay and comparative detection methods for characterization of polyethylene terephthalate hydrolases	34
Optical characterization and tunable antibacterial properties of gold nanoparticles with common proteins	33

A colorimetric aptamer-based method for detection of cadmium using the enhanced peroxidase-like activity of Au–MoS2 nanocomposites	31
Bioactive compounds guided diversity of endophytic fungi from Baliospermum montanum and their potential extracellular enzymes	30
Aptasensors for mycotoxin detection: A review	30
An immunosensor for the determination of carcinoembryonic antigen by Surface Plasmon Resonance imaging	29
Advances in amplification-free detection of nucleic acid: CRISPR/Cas system as a powerful tool	29
Recent advances in fluorescent probes for extracellular pH detection and imaging	28
LPI-CNNCP: Prediction of lncRNA-protein interactions by using convolutional neural network with the copy-padding trick	28
Development of a label-free electrochemical aptasensor based on diazonium electrodeposition: Application to cadmium detection in water	27
Gene selection using hybrid dragonfly black hole algorithm: A case study on RNA-seq COVID-19 data	26
Enhancing enzymatic activity of Mn@Co3O4 nanosheets as mimetic nanozyme for colorimetric assay of ascorbic acid	26
Validation of LC-MS/MS methods for determination of remdesivir and its metabolites GS-441524 and GS-704277 in acidified human plasma and their application in COVID-19 related clinical studies	26
Novel approaches for rapid detection of COVID-19 during the pandemic: A review	25
Electrochemical biosensor for miRNA-21 based on gold-platinum bimetallic nanoparticles coated 3-aminopropyltriethoxy silane	25
Advances in diagnosis of Helicobacter pylori through biosensors: Point of care devices	25
An aptamer biosensor based dual signal amplification system for the detection of salmonella typhimurium	25
Mechanism of antibodies purification by protein A	25
DeepPPSite: A deep learning-based model for analysis and prediction of phosphorylation sites using efficient sequence information	24
DeepACTION: A deep learning-based method for predicting novel drug-target interactions	23
Synergetic performance of isothermal amplification techniques and lateral flow approach for nucleic acid diagnostics	23
Pipette-tip SPE based on Graphene/ZnCr LDH for Pb(II) analysis in hair samples followed by GFAAS	23
Fast room temperature cloud point extraction procedure for spectrophotometric determination of phosphate in water samples	23
An overview of recent analysis and detection of acetylcholine	23
Electrochemical immunosensor based on AuNPs/Zn/Ni-ZIF-8-800@graphene for rapid detection of aflatoxin B1 in peanut oil	22
Analysis of multiple mycotoxins-contaminated wheat by a smart analysis platform	22
Application of the catalytic activity of gold nanoparticles for development of optical aptasensors	22
Pandora box of BCA assay. Investigation of the accuracy and linearity of the microplate bicinchoninic protein assay: Analytical challenges and method modifications to minimize systematic errors	22
HPLC methods for quantifying anticancer drugs in human samples: A systematic review	21
Resazurin rapid screening for antibacterial activities of organic and inorganic nanoparticles: Potential, limitations and precautions	21
Advances in fluorescent probes for detection and imaging of endogenous tyrosinase activity	21
Chaetomium globosum extract mediated gold nanoparticle synthesis and potent anti-inflammatory activity	21
The mechanism and improvements to the isothermal amplification of nucleic acids, at a glance	21
α-Glucosidase immobilization on polydopamine-coated cellulose filter paper and enzyme inhibitor screening	21
Label-free liquid crystal-based biosensor for detection of dopamine using DNA aptamer as a recognition probe	20
Global analysis of protein stability by temperature and chemical denaturation	19
Determination of homocysteine thiolactone in human urine by capillary zone electrophoresis and single drop microextraction	19
Recent advances on protein-based quantification of extracellular vesicles	19
Conventional and nanotechnology based sensors for creatinine (A kidney biomarker) detection: A consolidated review	19
Biosensors, microfluidics systems and lateral flow assays for circulating microRNA detection: A review	19
Rapid simultaneous detection of fumonisin B1 and deoxynivalenol in grain by immunochromatographic test strip	19
Glycopeptide variable window SWATH for improved data independent acquisition glycoprotein analysis	18
Outlook of therapeutic and diagnostic competency of nanobodies against SARS-CoV-2: A systematic review	18
Rapid and sensitive recombinase polymerase amplification combined with lateral flow strips for detecting Candida albicans	18
deepMDDI: A deep graph convolutional network framework for multi-label prediction of drug-drug interactions	18
Simultaneous detection of three zoonotic pathogens based on phage display peptide and multicolor quantum dots	18
Cross-priming isothermal amplification combined with nucleic acid test strips for detection of meat species	17
A high affinity modified DNA aptamer containing base-appended bases for human β-defensin	17
m7GPredictor: An improved machine learning-based model for predicting internal m7G modifications using sequence properties	17
1H-NMR-based urinary metabolomic analysis for the preventive effects of gushudan on glucocorticoid-induced osteoporosis rats	17
Optical-based biosensor for detection of oncomarker CA 125, recent progress and current status	17
Gold nanoparticles plated porous silicon nanopowder for nonenzymatic voltammetric detection of hydrogen peroxide	17

Molecularly imprinted nanofilms for endotoxin detection using an surface plasmon resonance sensor	17
Colorimetric method for Salmonella spp. detection based on peroxidase-like activity of Cu(II)-rGO nanoparticles and PCR	17
Quantitative analysis of protein in thermosensitive hydroxypropyl chitin for biomedical applications	16
KD-KLNMF: Identification of lncRNAs subcellular localization with multiple features and nonnegative matrix factorization	16
Development of DNA methylation markers for sperm, saliva and blood identification using pyrosequencing and qPCR/HRM	16
4mC-RF: Improving the prediction of 4mC sites using composition and position relative features and statistical moment	16
Lateral flow immunoassay based on gold magnetic nanoparticles for the protein quantitative detection: Prostate-specific antigen	16
Enzyme immobilization on glass fiber membrane for detection of halogenated compounds	16
Multiple fluorescence immunoassay for the simultaneous detection of Zearalenone and Ochratoxin A	16
A high-resolution multi-attribute method for product characterization, process characterization, and quality control of therapeutic proteins	16
Potential anticarcinogenic effect of goat milk-derived bioactive peptides on HCT-116 human colorectal carcinoma cell line	15
A new 1,2,3-triazole and its rhodamine B derivatives as a fluorescence probe for mercury ions	15
Detection system of the intracellular nitric oxide in yeast by HPLC with a fluorescence detector	15
Improved host cell protein analysis in monoclonal antibody products through ProteoMiner	15
Development of fluorescence polarization-based competition assay for nicotinamide N-methyltransferase	15
Ligand binding to natural and modified human serum albumin	15
Inhibitors of blood coagulation factor XIII	15
Recent advances in aptamer applications for analytical biochemistry	15
Mathematical approaches in estimating aptamer-target binding affinity	14
A critical review of bile acids and their receptors in hepatic encephalopathy	14
ES-ARCNN: Predicting enhancer strength by using data augmentation and residual convolutional neural network	14
RPA-SYBR Green I based instrument-free visual detection for pathogenic Yersinia enterocolitica in meat	14
Propofol suppresses colorectal cancer development by the circ-PABPN1/miR-638/SRSF1 axis	14
A novel fluorescent probe with extremely low background fluorescence for sensing hypochlorite in zebrafish	14
Ultrasensitive colorimetric detection of amoxicillin based on Tris-HCl-induced aggregation of gold nanoparticles	13
A dicyanoisophorone-based, near-infrared, lysosome-targeting pH sensor with an extremely large Stokes shift	13
Utility of 5-(2′,4′-dimethylphenylazo)-6-hydroxy-pyrimidine-2,4-dione in PVC membrane for a novel green optical chemical sensor to detect zinc ion in environmental samples	13
A user's guide to multicolor flow cytometry panels for comprehensive immune profiling	13
iEnhancer-RD: Identification of enhancers and their strength using RKPK features and deep neural networks	13
Selective chemiluminescent TURN-ON quantitative bioassay and imaging of intracellular hydrogen peroxide in human living cells	13
Spectral analysis combined with nonlinear optical measurement of laser printed biopolymer composites comprising chitosan/SWCNT	13
Advantages of formate dehydrogenase reaction for efficient NAD+ quantification in biological samples	13
Ligand binding constants for human serum albumin evaluated by ratiometric analysis of DSC thermograms	13
Recent developments of aptamer-based lateral flow assays for point-of-care (POC) diagnostics	13
A four-channel paper microfluidic device with gold nanoparticles and aptamers for seized drugs	13
A novel rapid detection of Senecavirus A using recombinase polymerase amplification (RPA) coupled with lateral flow (LF) dipstrip	12
DNA aptamer selection for SARS-CoV-2 spike glycoprotein detection	12
Identification of new biomarkers of pyridoxine-dependent epilepsy by GC/MS-based urine metabolomics	12
Determination of proteinaceous free amino acids by gas chromatography	12
Development of a LAMP method for detecting the N75S mutant in SDHI-resistant Corynespora cassiicola	12
Rapid detection of norovirus genogroup II in clinical and environmental samples using recombinase polymerase amplification	12
Reversibility and irreversibility in the temperature denaturation of monoclonal antibodies	12
High throughput quantification of short nucleic acid samples by capillary electrophoresis with automated data processing	12
Cutting-edge mass spectrometry strategy based on imaged capillary isoelectric focusing (icIEF) technology for characterizing charge heterogeneity of monoclonal antibody	12
Imaging of the ex vivo transglutaminase activity in liver macrophages of sepsis mice	12
Fluorescent contact lens for continuous non-invasive measurements of sodium and chloride ion concentrations in tears	12
Recombinant expression of ecto-nucleotide pyrophosphatase/phosphodiesterase 4 (NPP4) and development of a luminescence-based assay to identify inhibitors	12
Rapid and convenient biotransformation procedure for human drug metabolizing enzymes using permeabilized fission yeast cells	12
Fast and cost-effective preparation of plant cells for scanning electron microscopy (SEM) analysis	12
Cerebrovascular alterations in NAFLD: Is it increasing our risk of Alzheimer's disease?	12
Simple kinetics, assay, and trends for soil microbial catalases	12
Overexpression and characterization of TnCel12B, a hyperthermophilic GH12 endo-1,4-β-glucanase cloned from Thermotoga naphthophila RKU-10T	12
Overview of oxidative stress findings in hepatic encephalopathy: From cellular and ammonium-based animal models to human data	11
Determination of miRNA derived from exosomes of prostate cancer via toehold-aided cyclic amplification combined with HRP enzyme catalysis and magnetic nanoparticles	11
Mutual effects of protein corona formation on CdTe quantum dots	11
Determination of free fatty acids in plasma by gas chromatography	11
LINC01116 regulates proliferation, migration, and apoptosis of keloid fibroblasts by the TGF-β1/SMAD3 signaling via targeting miR-3141	11
Measurement of the tripeptides glutathione and ophthalmic acid by gas chromatography-mass spectrometry	11
Simultaneous determination of flavonoids and anthraquinones in honey by using SPE-CE-LIF	11
An ultrasensitive electrochemical DNA biosensor for monitoring Human papillomavirus-16 (HPV-16) using graphene oxide/Ag/Au nano-biohybrids	11
Some novel rare earth metal ions complexes: Synthesis, characterization, luminescence and biocidal efficiency	11
Surface analysis of ancient parchments via the EVA film: The Aleppo Codex	11
Development of peptide aptamers as alternatives for antibody in the detection of amyloid-beta 42 aggregates	11
Improving the detection limit of Salmonella colorimetry using long ssDNA of asymmetric-PCR and non-functionalized AuNPs	11
iPromoter-ET: Identifying promoters and their strength by extremely randomized trees-based feature selection	11
Characterization and monitoring of charge variants of a recombinant monoclonal antibody using microfluidic capillary electrophoresis-mass spectrometry	11
Combining two optimized and affordable methods to assign chemoreceptors to a specific signal	11
Nanomaterials and metal-organic frameworks for biosensing applications of mutations of the emerging viruses	11
Comparative metabolism of schaftoside in healthy and calcium oxalate kidney stone rats by UHPLC-Q-TOF-MS/MS method	11
Ratiometric electrochemical aptasensor for the sensitive detection of carcinoembryonic antigen based on a hairpin DNA probe and exonuclease I-assisted target recycling	11
Split-luciferase complementary assay of NLRP3 PYD-PYD interaction indicates inflammasome formation during inflammation	11
Nucleotide binding kinetics and conformational change analysis of tissue transglutaminase with switchSENSE	11
Ultra-fast, high throughput and inexpensive detection of SARS-CoV-2 seroconversion using Ni2+ magnetic beads	11
A simplified method for the quantitation of short-chain fatty acids in human stool	11
Emerging methods and applications of ultra-high field MR spectroscopic imaging in the human brain	11
The status of proteomics as we enter the 2020s: Towards personalised/precision medicine	11
Electrochemiluminescence immunosensor based on the quenching effect of CuO@GO on m-CNNS for cTnI detection	11
Nucleic acid extraction without electrical equipment via magnetic nanoparticles in Pasteur pipettes for pathogen detection	11
Multi-wavelength analytical ultracentrifugation of biopolymer mixtures and interactions	10
Carbon dots and graphene oxide based FRET immunosensor for sensitive detection of Helicobacter pylori	10

New insight into G-quadruplexes; diagnosis application in cancer	10
2-Phenoxyethanol: A novel reagent for improved sensitivity of carbohydrate quantification	10
Amino acids, ammonia, and hepatic encephalopathy	10
Sensitive and reversible perylene derivative-based fluorescent probe for acetylcholinesterase activity monitoring and its inhibitor	10
Analysis of the expression of transglutaminases in the reconstructed human epidermis using a three-dimensional cell culture	10
Fifteen years of urea cycle disorders brain research: Looking back, looking forward	10
Gamma-irradiated fenugreek extracts mediates resistance to rice blast disease through modulating histochemical and biochemical changes	10
A dual-signaling electrochemical ratiometric strategy combining “signal-off” and “signal-on” approaches for detection of MicroRNAs	10
A comprehensive guide to MEGA-PRESS for GABA measurement	10
Improving the stability of the malachite green method for the determination of phosphate using Pluronic F68	10
Real-time monitoring and effector screening of APE1 based on rGO assisted DNA nanoprobe	10
Accurate prediction of species-specific 2-hydroxyisobutyrylation sites based on machine learning frameworks	10
Colorimetric biosensing of nopaline synthase terminator using Fe3O4@Au and hemin-functionalized reduced graphene oxide	10
Green synthesized Ag-nanoparticles using Scutellaria multicaulis stem extract and their selective cytotoxicity against breast cancer	10
Monitoring polysorbate hydrolysis in therapeutic proteins using an ultrasensitive extraction-free fatty acid quantitation method	10
Determination of copper by AAS in tear fluid of patients with keratoconus	10
Determination of polycyclic aromatic hydrocarbons (PAHs) in smoking cessation aids by using high-performance liquid chromatography	10
A magainin-2 like bacteriocin BpSl14 with anticancer action from fish gut Bacillus safensis SDG14	10
The metabolic importance of the glutaminase II pathway in normal and cancerous cells	10
Investigation of the Hg(II) biosorption from wastewater by using garlic plant and differential pulse voltammetry	10
Recent advances in morphology, aperture control, functional control and electrochemical sensors applications of carbon nanofibers	10
An effective method for saliva stabilization and magnetic nanoparticles based DNA extraction for genomic applications	9
An immobilized invertase enzyme for the selective determination of sucrose in fruit juices	9
Evaluating the interplay among stationary phases/ion-pairing reagents/sequences for liquid chromatography mass spectrometry analysis of oligonucleotides	9
The development of a colorimetric biosensing assay for the detection of Helicobacter pylori in feces	9
Evaluating line-broadening factors on a reference spectrum as a bucketing method for NMR based metabolomics	9
A new fluorescence probe for detection of Cu+2 in blood samples: Circuit logic gate	9
Detection of Acinetobacter baumannii in fresh produce using modified magnetic nanoparticles and PCR	9
Bona fide gene expression analysis of samples from the bovine reproductive system by microfluidic platform	9
Intermittent fasting-induced biomolecular modifications in rat tissues detected by ATR-FTIR spectroscopy and machine learning algorithms	9
Nanozyme based on ZIF-8 for the colorimetric detection of sulfonamides in cow milk	9
A new ELISA assay demonstrates sex differences in the concentration of serum polysialic acid	9
Advancing secondary structure characterization of monoclonal antibodies using Microfluidic Modulation Spectroscopy	9
Resolving interactions of miglitol with normal and glycated human serum albumin by multivariate methods	9
Improved dual luciferase reporter (DLR) assay to determine the protein stability	9
PET CMRglc mapping and 1H-MRS show altered glucose uptake and neurometabolic profiles in BDL rats	9
An electrochemical biosensor for direct detection of hepatitis C virus	9
Quick and convenient construction of lambda-cyhalothrin antigen for the generation of specific antibody	9
Discriminative electrochemical biosensing of wildtype and omicron variant of SARS-CoV-2 nucleocapsid protein with single platform	9
Development of a sensitive sandwich-ELISA assay for reliable detection of fish residues in foods	9
Comparison of spermatozoal RNA extraction methods in goats	9
Polydimethylsiloxane/ZIF-8@GO sponge headspace solid-phase extraction followed by GC-MS for the analysis of lavender essential oil	9
PolyTag: A peptide tag that affords scaffold-less covalent protein assembly catalyzed by microbial transglutaminase	9
Impact of transposable elements on genome size variation between two closely related crustacean species	9
Porphyrin NanoMOFs as a catalytic label in nanozyme-linked immunosorbent assay for Aflatoxin B1 detection	9
1H NMR serum metabolomics and its endogenous network pharmacological analysis of Gushudan on kidney-yang-deficiency-syndrome rats	8
TMPpred: A support vector machine-based thermophilic protein identifier	8
Using differential scanning calorimetry for the development of non-reduced capillary electrophoresis sodium dodecyl sulfate methods for monoclonal antibodies	8
Insights into the heparan sulphate-dependent externalisation of transglutaminase-2 (TG2) in glucose-stimulated proximal-like tubular epithelial cells	8
Detecting Mycobacterium tuberculosis complex and rifampicin resistance via a new rapid multienzyme isothermal point mutation assay	8
Normalizing polydiacetylene colorimetric assays of vesicle binding across lipid systems	8
Early detection of Huanglongbing with EESI-MS indicates a role of phenylpropanoid pathway in citrus	8
Determination of certain urinary microRNAs as promising biomarkers in diabetic nephropathy patients using gold nanoparticles	8
Stain-Free total-protein normalization enhances the reproducibility of Western blot data	8
High-throughput and high-sensitivity N-Glycan profiling: A platform for biopharmaceutical development and disease biomarker discovery	8
Establishment and clinical application of time-resolved immunofluorescence assay of lipoprotein-associated phospholipase A2	8
Very long-term stability of lipid biomarkers in human serum	8
Cryopreservation without dry ice-induced acidification during sample transport	8
Detection of bladder cancer with aberrantly fucosylated ITGA3	8
Enantioselective determination of econazole in rat plasma and its application to a pharmacokinetic study	8
Protection function of 18β-glycyrrhetinic acid on rats with high-altitude pulmonary hypertension based on 1H NMR metabonomics technology	8
Sarcopenia in liver cirrhosis: Prevalence, pathophysiology and therapeutic strategies	8
Quantitative MALDI-MS assay of steroid hormones in plasma based on hydroxylamine derivatization	8
A rapid responsive coumarin-naphthalene derivative for the detection of cyanide ions in cell culture	8
Single-stranded and double-stranded DNA-binding protein prediction using HMM profiles	8
Optimizations of a novel fluorescence polarization-based high-throughput screening assay for β-catenin/LEF1 interaction inhibitors	8
A miniature CuO nanoarray sensor for noninvasive detection of trace salivary glucose	8
Coumarin-based fluorescent probes toward viscosity in mitochondrion/lysosome	8
Application of Natural Deep Eutectic Solvents for the metal nanoparticles extraction from plant tissue	8
Colorimetric detection of homocysteine by a pyridylazo dye-based Cu2+ complex via indicator displacement mechanism	8
Single probe PCR melting curve analysis MTHFR C677T SNP sites	8
Inhibition of cell migration and invasion by ICAM-1 binding DNA aptamers	8
A microplate screen to estimate metal-binding affinities of metalloproteins	8
Raman spectroscopy combined with comprehensive gas chromatography for label-free characterization of plasma-derived extracellular vesicle subpopulations	8
Recent progress in electrochemical sensors for detection and quantification of malaria	8
A novel DNA tweezers-based nanobiosensor for multiple detections of circulating exosomal microRNAs in breast cancer	8
Kinetic analyses of two-steps oxidation from l-tyrosine to l-dopaquinone with tyrosinase by capillary electrophoresis/dynamic frontal analysis	8
Ultrasensitive ELISA detection of proteins in separated lumen and membrane fractions of cancer cell exosomes	8
Blood ammonia in patients with chronic liver diseases: A better defined role in clinical practice	8
Mechanistic insights into the pathophysiology of cirrhotic cardiomyopathy	8
A fluorescence quenching-recovery sensor based on RCA for the specific analysis of Fusobacterium nucleatum. nucleatum	8
Polydopamine nanospheres-assisted direct PCR for rapid detection of Escherichia coli O157:H7	7
Development of a HPLC-MS/MS method for assessment of thiol redox status in human tear fluids	7
Bovine serum albumin determination based on methylene blue detection by photothermal lens spectroscopy	7
Quantification of monosaccharide enantiomers using optical properties of hydrogen-bonded tryptophan	7
Development of a fluorescence-based assay for screening of urate transporter 1 inhibitors using 6-carboxyfluorescein	7
Mitochondrial DNA methylation misleads global DNA methylation detected by antibody-based methods	7
Development of a noncompetitive magnetic-phage anti-immunocomplex assay for detecting of organophosphorus pesticides with a thiophosphate group	7
Lateral flow immunoassay with peptide-functionalized gold nanoparticles for rapid detection of protein tyrosine phosphatase 1B	7
LC-MS/MS quantification of fat soluble vitamers – A systematic review	7
Flow cytometric determination of cell cycle progression via direct labeling of replicated DNA	7
A novel electrochemical immunosensor based on SnS2/NiCo metal-organic frameworks loaded with gold nanoparticles for cortisol detection	7
Metabolomics in liver injury induced by dietary cadmium exposure and protective effect of calcium supplementation	7
Direct electrochemical detection of enzyme labelled, isothermally amplified DNA	7
Detection of small DNA fragments by biolayer interferometry	7