Acta Neuropathologica

Article	Citations
Plasma p-tau231: a new biomarker for incipient Alzheimer’s disease pathology	336
Distinct amyloid-β and tau-associated microglia profiles in Alzheimer’s disease	195
Periphery and brain, innate and adaptive immunity in Parkinson’s disease	160
Neuropathological consensus criteria for the evaluation of Lewy pathology in post-mortem brains: a multi-centre study	134
Plasma biomarkers for Alzheimer’s Disease in relation to neuropathology and cognitive change	120
Cryo-EM structures of tau filaments from Alzheimer’s disease with PET ligand APN-1607	119
Microglia and monocytes in inflammatory CNS disease: integrating phenotype and function	113
Diverse human astrocyte and microglial transcriptional responses to Alzheimer’s pathology	102
The olfactory nerve is not a likely route to brain infection in COVID-19: a critical review of data from humans and animal models	99
α-Synuclein in blood exosomes immunoprecipitated using neuronal and oligodendroglial markers distinguishes Parkinson’s disease from multiple system atrophy	90
Tau strains shape disease	89
Mitochondrial bioenergetic deficits in C9orf72 amyotrophic lateral sclerosis motor neurons cause dysfunctional axonal homeostasis	86
The mechanistic link between selective vulnerability of the locus coeruleus and neurodegeneration in Alzheimer’s disease	86
Frequency of LATE neuropathologic change across the spectrum of Alzheimer’s disease neuropathology: combined data from 13 community-based or population-based autopsy cohorts	81
The subcellular arrangement of alpha-synuclein proteoforms in the Parkinson’s disease brain as revealed by multicolor STED microscopy	78
Exosomes induce endolysosomal permeabilization as a gateway by which exosomal tau seeds escape into the cytosol	75
Pyroptosis in Alzheimer’s disease: cell type-specific activation in microglia, astrocytes and neurons	75
Analyzing microglial phenotypes across neuropathologies: a practical guide	74
TERT promoter mutation status is necessary and sufficient to diagnose IDH-wildtype diffuse astrocytic glioma with molecular features of glioblastoma	65
Perivascular space dilation is associated with vascular amyloid-β accumulation in the overlying cortex	64
Chronic traumatic encephalopathy (CTE): criteria for neuropathological diagnosis and relationship to repetitive head impacts	63
Neuron-specific activation of necroptosis signaling in multiple sclerosis cortical grey matter	62
Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential	60
Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis	60
Physiological and pathological functions of TMEM106B: a gene associated with brain aging and multiple brain disorders	59

LATE-NC staging in routine neuropathologic diagnosis: an update	59
White matter microglia heterogeneity in the CNS	56
Genome-wide meta-analysis for Alzheimer’s disease cerebrospinal fluid biomarkers	56
Atypical teratoid/rhabdoid tumors (ATRTs) with SMARCA4 mutation are molecularly distinct from SMARCB1-deficient cases	55
Meningeal inflammation in multiple sclerosis induces phenotypic changes in cortical microglia that differentially associate with neurodegeneration	54
Lewy pathology of the esophagus correlates with the progression of Lewy body disease: a Japanese cohort study of autopsy cases	53
Frontal white matter lesions in Alzheimer’s disease are associated with both small vessel disease and AD-associated cortical pathology	52
Structure of Tau filaments in Prion protein amyloidoses	52
Complement component 3 from astrocytes mediates retinal ganglion cell loss during neuroinflammation	50
Profiling the neurovascular unit unveils detrimental effects of osteopontin on the blood–brain barrier in acute ischemic stroke	50
Rainwater Charitable Foundation criteria for the neuropathologic diagnosis of progressive supranuclear palsy	50
R1441G but not G2019S mutation enhances LRRK2 mediated Rab10 phosphorylation in human peripheral blood neutrophils	49
Clinical and molecular heterogeneity of pineal parenchymal tumors: a consensus study	47
Selective vulnerability of inhibitory networks in multiple sclerosis	46
Retinal pathological features and proteome signatures of Alzheimer’s disease	45
Distinct tau neuropathology and cellular profiles of an APOE3 Christchurch homozygote protected against autosomal dominant Alzheimer’s dementia	45
Integrated molecular and clinical analysis of low-grade gliomas in children with neurofibromatosis type 1 (NF1)	43
Subgroup and subtype-specific outcomes in adult medulloblastoma	41
Supratentorial ependymoma in childhood: more than just RELA or YAP	40
Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors	39
Cryo-EM structures of prion protein filaments from Gerstmann–Sträussler–Scheinker disease	39
PATZ1 fusions define a novel molecularly distinct neuroepithelial tumor entity with a broad histological spectrum	39
Upstream open reading frame with NOTCH2NLC GGC expansion generates polyglycine aggregates and disrupts nucleocytoplasmic transport: implications for polyglycine diseases	38
BTK inhibition limits B-cell–T-cell interaction through modulation of B-cell metabolism: implications for multiple sclerosis therapy	38
Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites	38
Maturation of neuronal AD-tau pathology involves site-specific phosphorylation of cytoplasmic and synaptic tau preceding conformational change and fibril formation	38
Cross-platform transcriptional profiling identifies common and distinct molecular pathologies in Lewy body diseases	38
Making sense of missense variants in TTN-related congenital myopathies	37
Seizure-mediated iron accumulation and dysregulated iron metabolism after status epilepticus and in temporal lobe epilepsy	37
Lipids, lysosomes and mitochondria: insights into Lewy body formation from rare monogenic disorders	36
Cryo-EM structures of amyloid-β filaments with the Arctic mutation (E22G) from human and mouse brains	35
In vitro amplification of pathogenic tau conserves disease-specific bioactive characteristics	35
Clear cell meningiomas are defined by a highly distinct DNA methylation profile and mutations in SMARCE1	35
Necrotic reshaping of the glioma microenvironment drives disease progression	34
Non-IDH1-R132H IDH1/2 mutations are associated with increased DNA methylation and improved survival in astrocytomas, compared to IDH1-R132H mutations	34
A multifactorial model of pathology for age of onset heterogeneity in familial Alzheimer’s disease	34
The proteome of granulovacuolar degeneration and neurofibrillary tangles in Alzheimer’s disease	34
Complement-associated loss of CA2 inhibitory synapses in the demyelinated hippocampus impairs memory	34
Altered ceramide metabolism is a feature in the extracellular vesicle-mediated spread of alpha-synuclein in Lewy body disorders	33
APOE4 exacerbates α-synuclein seeding activity and contributes to neurotoxicity in Alzheimer’s disease with Lewy body pathology	33
Physiological β-amyloid clearance by the liver and its therapeutic potential for Alzheimer’s disease	32
Single-cell profiling of myasthenia gravis identifies a pathogenic T cell signature	32
Ultrastructural and biochemical classification of pathogenic tau, α-synuclein and TDP-43	32
Distinct characteristics of limbic-predominant age-related TDP-43 encephalopathy in Lewy body disease	31
Spatiotemporal characterization of cellular tau pathology in the human locus coeruleus–pericoerulear complex by three-dimensional imaging	31
Accumulation of TMEM106B C-terminal fragments in neurodegenerative disease and aging	31
Malignant transformation of a polymorphous low grade neuroepithelial tumor of the young (PLNTY)	30
Trafficking of the glutamate transporter is impaired in LRRK2-related Parkinson’s disease	30
New SNCA mutation and structures of α-synuclein filaments from juvenile-onset synucleinopathy	30
Apolipoprotein E regulates lipid metabolism and α-synuclein pathology in human iPSC-derived cerebral organoids	29

Altered oligodendroglia and astroglia in chronic traumatic encephalopathy	29
Glioblastomas with primitive neuronal component harbor a distinct methylation and copy-number profile with inactivation of TP53, PTEN, and RB1	29
Multi-omic molecular profiling reveals potentially targetable abnormalities shared across multiple histologies of brain metastasis	29
Rapid-CNS2: rapid comprehensive adaptive nanopore-sequencing of CNS tumors, a proof-of-concept study	28
Heterogeneity in α-synuclein fibril activity correlates to disease phenotypes in Lewy body dementia	28
Skeletal muscle provides the immunological micro-milieu for specific plasma cells in anti-synthetase syndrome-associated myositis	28
HnRNP K mislocalisation is a novel protein pathology of frontotemporal lobar degeneration and ageing and leads to cryptic splicing	28
Oligodendroglia heterogeneity in the human central nervous system	28
ApoE4 inhibition of VMAT2 in the locus coeruleus exacerbates Tau pathology in Alzheimer’s disease	27
CSF p-tau increase in response to Aβ-type and Danish-type cerebral amyloidosis and in the absence of neurofibrillary tangles	27
Tau immunotherapy is associated with glial responses in FTLD-tau	27
Biomarkers for parkinsonian disorders in CNS-originating EVs: promise and challenges	27
Patterns of amygdala region pathology in LATE-NC: subtypes that differ with regard to TDP-43 histopathology, genetic risk factors, and comorbid pathologies	27
Transmission of cervid prions to humanized mice demonstrates the zoonotic potential of CWD	27
Targeting cancer stem cells in medulloblastoma by inhibiting AMBRA1 dual function in autophagy and STAT3 signalling	27
Heterogeneity of white matter astrocytes in the human brain	26
Increased pyroptosis activation in white matter microglia is associated with neuronal loss in ALS motor cortex	26
FMNL2 regulates gliovascular interactions and is associated with vascular risk factors and cerebrovascular pathology in Alzheimer’s disease	26
Phenotypic diversity of genetic Creutzfeldt–Jakob disease: a histo-molecular-based classification	26
Mutations within FGFR1 are associated with superior outcome in a series of 83 diffuse midline gliomas with H3F3A K27M mutations	26
Wolframin is a novel regulator of tau pathology and neurodegeneration	26
TDP-43 drives synaptic and cognitive deterioration following traumatic brain injury	25
Developmental malformations in Huntington disease: neuropathologic evidence of focal neuronal migration defects in a subset of adult brains	25
The oncogenic fusion landscape in pediatric CNS neoplasms	25
Alzheimer disease neuropathology in a patient previously treated with aducanumab	24
Association of small vessel disease with tau pathology	24
Vagus nerve inflammation contributes to dysautonomia in COVID-19	24
Dominant-acting CSF1R variants cause microglial depletion and altered astrocytic phenotype in zebrafish and adult-onset leukodystrophy	24
Systemic sclerosis-associated myositis features minimal inflammation and characteristic capillary pathology	24
Intellectual disability: dendritic anomalies and emerging genetic perspectives	23
Galectin-3 is elevated in CSF and is associated with Aβ deposits and tau aggregates in brain tissue in Alzheimer’s disease	23
Transcriptomic analysis of frontotemporal lobar degeneration with TDP-43 pathology reveals cellular alterations across multiple brain regions	22
A new non-aggregative splicing isoform of human Tau is decreased in Alzheimer’s disease	22
Oligosarcomas, IDH-mutant are distinct and aggressive	22
Genome-wide association study and functional validation implicates JADE1 in tauopathy	22
Cross-regional homeostatic and reactive glial signatures in multiple sclerosis	22
TREM2 expression in the brain and biological fluids in prion diseases	22
Limbic-predominant age-related TDP-43 encephalopathy neuropathological change (LATE-NC) is independently associated with dementia and strongly associated with arteriolosclerosis in the oldest-old	21
DNA methylation-based classification of malformations of cortical development in the human brain	21
An interaction between synapsin and C9orf72 regulates excitatory synapses and is impaired in ALS/FTD	21
Adaptive structural changes in the motor cortex and white matter in Parkinson’s disease	21
Transmissible α-synuclein seeding activity in brain and stomach of patients with Parkinson’s disease	21
Consequences of variability in α-synuclein fibril structure on strain biology	21
TERT promoter mutation and chromosome 6 loss define a high-risk subtype of ependymoma evolving from posterior fossa subependymoma	21
DDX17 is involved in DNA damage repair and modifies FUS toxicity in an RGG-domain dependent manner	21
Alzheimer’s disease neuropathological change three decades after iatrogenic amyloid-β transmission	21
EZHIP: a new piece of the puzzle towards understanding pediatric posterior fossa ependymoma	21
Histopathology of the cerebellar cortex in essential tremor and other neurodegenerative motor disorders: comparative analysis of 320 brains	20
Identification of TMEM106B amyloid fibrils provides an updated view of TMEM106B biology in health and disease	20
PSD-93 up-regulates the synaptic activity of corticotropin-releasing hormone neurons in the paraventricular nucleus in depression	20
TDP-43 interacts with pathological τ protein in Alzheimer’s disease	20
Immunisation with UB-312 in the Thy1SNCA mouse prevents motor performance deficits and oligomeric α-synuclein accumulation in the brain and gut	20
Phosphorylated tau in the retina correlates with tau pathology in the brain in Alzheimer’s disease and primary tauopathies	20
Neuronal spreading and plaque induction of intracellular Aβ and its disruption of Aβ homeostasis	20
Loss of LAMP5 interneurons drives neuronal network dysfunction in Alzheimer’s disease	19
Plasma p-tau181 and p-tau217 in discriminating PART, AD and other key neuropathologies in older adults	19
Comparing amyloid-β plaque burden with antemortem PiB PET in autosomal dominant and late-onset Alzheimer disease	19
Selective vulnerability of tripartite synapses in amyotrophic lateral sclerosis	19
Evidence of disrupted rhombic lip development in the pathogenesis of Dandy–Walker malformation	18
More than meets the eye in Parkinson’s disease and other synucleinopathies: from proteinopathy to lipidopathy	18
Molecular profiling of pediatric meningiomas shows tumor characteristics distinct from adult meningiomas	18
GOPC:ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types	18
Associations of psychiatric disease and ageing with FKBP5 expression converge on superficial layer neurons of the neocortex	18
Low-grade glioneuronal tumors with FGFR2 fusion resolve into a single epigenetic group corresponding to ‘Polymorphous low-grade neuroepithelial tumor of the young’	18
LRP10 interacts with SORL1 in the intracellular vesicle trafficking pathway in non-neuronal brain cells and localises to Lewy bodies in Parkinson’s disease and dementia with Lewy bodies	18
Multiplatform molecular analyses refine classification of gliomas arising in patients with neurofibromatosis type 1	18
Functional excitatory to inhibitory synaptic imbalance and loss of cognitive performance in people with Alzheimer’s disease neuropathologic change	17
Expanded analysis of high-grade astrocytoma with piloid features identifies an epigenetically and clinically distinct subtype associated with neurofibromatosis type 1	17
The proteomic landscape of glioblastoma recurrence reveals novel and targetable immunoregulatory drivers	17
Dysregulated coordination of MAPT exon 2 and exon 10 splicing underlies different tau pathologies in PSP and AD	17
Signature laminar distributions of pathology in frontotemporal lobar degeneration	17
Photodynamic studies reveal rapid formation and appreciable turnover of tau inclusions	17
Brain region-specific susceptibility of Lewy body pathology in synucleinopathies is governed by α-synuclein conformations	17
A network of core and subtype-specific gene expression programs in myositis	17
Receptor clustering and pathogenic complement activation in myasthenia gravis depend on synergy between antibodies with multiple subunit specificities	17
α-Synuclein molecular behavior and nigral proteomic profiling distinguish subtypes of Lewy body disorders	17
Tau seeding and spreading in vivo is supported by both AD-derived fibrillar and oligomeric tau	17
A glutaminyl cyclase-catalyzed α-synuclein modification identified in human synucleinopathies	17
ATRT–SHH comprises three molecular subgroups with characteristic clinical and histopathological features and prognostic significance	16
A novel ATXN1-DUX4 fusion expands the spectrum of ‘CIC-rearranged sarcoma’ of the CNS to include non-CIC alterations	16

Cryptic exon detection and transcriptomic changes revealed in single-nuclei RNA sequencing of C9ORF72 patients spanning the ALS-FTD spectrum	16
Targeting fibroblast growth factor receptors to combat aggressive ependymoma	16
Repetitive head impacts and chronic traumatic encephalopathy are associated with TDP-43 inclusions and hippocampal sclerosis	16
High-grade glioma with pleomorphic and pseudopapillary features (HPAP): a proposed type of circumscribed glioma in adults harboring frequent TP53 mutations and recurrent monosomy 13	16
Aminopeptidase A contributes to biochemical, anatomical and cognitive defects in Alzheimer’s disease (AD) mouse model and is increased at early stage in sporadic AD brain	16
Wide distribution of prion infectivity in the peripheral tissues of vCJD and sCJD patients	16
Antibodies to MOG in CSF only: pathological findings support the diagnostic value	16
Inflammation and the pathological progression of Alzheimer’s disease are associated with low circulating choline levels	16
Transcriptomic profiling of Parkinson's disease brains reveals disease stage specific gene expression changes	16
Defects in lysosomal function and lipid metabolism in human microglia harboring a TREM2 loss of function mutation	16
Concussion leads to widespread axonal sodium channel loss and disruption of the node of Ranvier	16
TMEM106B modifies TDP-43 pathology in human ALS brain and cell-based models of TDP-43 proteinopathy	16
Oncostatin M triggers brain inflammation by compromising blood–brain barrier integrity	15
Even heterozygous loss of CDKN2A/B greatly accelerates recurrence in aggressive meningioma	15
EWSR1-BEND2 fusion defines an epigenetically distinct subtype of astroblastoma	15
Frequency and distribution of TAR DNA-binding protein 43 (TDP-43) pathology increase linearly with age in a large cohort of older adults with and without dementia	15
Stress-inducible phosphoprotein 1 (HOP/STI1/STIP1) regulates the accumulation and toxicity of α-synuclein in vivo	15
Neurofibromatosis type 2 predisposes to ependymomas of various localization, histology, and molecular subtype	15
Genetic alterations of TP53 and OTX2 indicate increased risk of relapse in WNT medulloblastomas	15
Molecular characterization of DICER1-mutated pituitary blastoma	15
Multiple system atrophy prions transmit neurological disease to mice expressing wild-type human α-synuclein	15
Enhancer reprogramming in PRC2-deficient malignant peripheral nerve sheath tumors induces a targetable de-differentiated state	15
Oncohistone interactome profiling uncovers contrasting oncogenic mechanisms and identifies potential therapeutic targets in high grade glioma	15
Heteroplasmic mitochondrial DNA mutations in frontotemporal lobar degeneration	14
Intratumor and informatic heterogeneity influence meningioma molecular classification	14
Unique seeding profiles and prion-like propagation of synucleinopathies are highly dependent on the host in human α-synuclein transgenic mice	14
TREM2 gene expression associations with Alzheimer’s disease neuropathology are region-specific: implications for cortical versus subcortical microglia	14
Environmental and host factors that contribute to prion strain evolution	14
Nuclear depletion of RNA-binding protein ELAVL3 (HuC) in sporadic and familial amyotrophic lateral sclerosis	14
A recurrent homozygous ACTN2 variant associated with core myopathy	13
Neuropathological associations of limbic-predominant age-related TDP-43 encephalopathy neuropathological change (LATE-NC) differ between the oldest-old and younger-old	13
Donanemab detects a minor fraction of amyloid-β plaques in post-mortem brain tissue of patients with Alzheimer’s disease and Down syndrome	13
Analysis of inflammatory markers and tau deposits in an autopsy series of nine patients with anti-IgLON5 disease	13
Aberrant NOVA1 function disrupts alternative splicing in early stages of amyotrophic lateral sclerosis	13
Improved prognostic stratification of patients with isocitrate dehydrogenase-mutant astrocytoma	13
Identification of retinoblastoma binding protein 7 (Rbbp7) as a mediator against tau acetylation and subsequent neuronal loss in Alzheimer’s disease and related tauopathies	13
Cell-specific MAPT gene expression is preserved in neuronal and glial tau cytopathologies in progressive supranuclear palsy	13
Huntington’s disease brain-derived small RNAs recapitulate associated neuropathology in mice	13
Amplification of the PLAG-family genes—PLAGL1 and PLAGL2—is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification	13
DNA methylation analysis of glioblastomas harboring FGFR3-TACC3 fusions identifies a methylation subclass with better patient survival	13
Early white matter pathology in the fornix of the limbic system in Huntington disease	13
Performance of a seed amplification assay for misfolded alpha-synuclein in cerebrospinal fluid and brain tissue in relation to Lewy body disease stage and pathology burden	13
Amyotrophic lateral sclerosis is over-represented in two Huntington’s disease brain bank cohorts: further evidence to support genetic pleiotropy of pathogenic HTT gene expansion	12
Neuropathology of central nervous system involvement in TTR amyloidosis	12
PolyGA targets the ER stress-adaptive response by impairing GRP75 function at the MAM in C9ORF72-ALS/FTD	12
Mutant LRRK2 exacerbates immune response and neurodegeneration in a chronic model of experimental colitis	12
Mutation ∆K281 in MAPT causes Pick’s disease	12
Increased mRNA expression of CDKN2A is a transcriptomic marker of clinically aggressive meningiomas	12
Glioneuronal tumor with ATRX alteration, kinase fusion and anaplastic features (GTAKA): a molecularly distinct brain tumor type with recurrent NTRK gene fusions	12
Clinical, genomic, and epigenomic analyses of H3K27M-mutant diffuse midline glioma long-term survivors reveal a distinct group of tumors with MAPK pathway alterations	12
Clinical and neuropathological diversity of tauopathy in MAPT duplication carriers	12
Two predominant molecular subtypes of spinal meningioma: thoracic NF2-mutant tumors strongly associated with female sex, and cervical AKT1-mutant tumors originating ventral to the spinal cord	12
Microglial contribution to the pathology of neurodevelopmental disorders in humans	12
Plasma biomarkers for prediction of Alzheimer’s disease neuropathologic change	12
Circular RNA profiling distinguishes medulloblastoma groups and shows aberrant RMST overexpression in WNT medulloblastoma	12
A new subtype of diffuse midline glioma, H3 K27 and BRAF/FGFR1 co-altered: a clinico-radiological and histomolecular characterisation	11
DTYMK is essential for genome integrity and neuronal survival	11
Phosphatidylinositol-3,4,5-trisphosphate interacts with alpha-synuclein and initiates its aggregation and formation of Parkinson’s disease-related fibril polymorphism	11
Evidence of traumatic brain injury in headbutting bovids	11
X-linked myotubular myopathy is associated with epigenetic alterations and is ameliorated by HDAC inhibition	11
C-terminal frameshift variant of TDP-43 with pronounced aggregation-propensity causes rimmed vacuole myopathy but not ALS/FTD	11
Cryptic splicing of stathmin-2 and UNC13A mRNAs is a pathological hallmark of TDP-43-associated Alzheimer’s disease	11
Neuropathologic scales of cerebrovascular disease associated with diffusion changes on MRI	11
Validation of the new pathology staging system for progressive supranuclear palsy	11
Loss of TDP-43 splicing repression occurs early in the aging population and is associated with Alzheimer’s disease neuropathologic changes and cognitive decline	11
HNRNPK alleviates RNA toxicity by counteracting DNA damage in C9orf72 ALS	10
A comprehensive genomic study of 390 H3F3A-mutant pediatric and adult diffuse high-grade gliomas, CNS WHO grade 4	10
Isoform-specific patterns of tau burden and neuronal degeneration in MAPT-associated frontotemporal lobar degeneration	10
Brain and spinal cord arteriolosclerosis and its associations with cerebrovascular disease risk factors in community-dwelling older adults	10
Limbic-predominant age-related TDP-43 proteinopathy (LATE-NC) is associated with abundant TMEM106B pathology	10
Loss of p16 expression is a sensitive marker of CDKN2A homozygous deletion in malignant meningiomas	10
ATP10B variants in Parkinson’s disease: a large cohort study in Chinese mainland population	10
DGCR8 and the six hit, three-step model of schwannomatosis	10
DICER1 syndrome in a young adult with pituitary blastoma	10
Missense mutations in small muscle protein X-linked (SMPX) cause distal myopathy with protein inclusions	10
Loss of function variants in DNAJB4 cause a myopathy with early respiratory failure	10
Risk of chronic traumatic encephalopathy in rugby union is associated with length of playing career	10
LRRK2 is reduced in Parkinson’s disease gut	9
Individual myasthenia gravis autoantibody clones can efficiently mediate multiple mechanisms of pathology	9
Characterization of hippocampal sclerosis of aging and its association with other neuropathologic changes and cognitive deficits in the oldest-old	9
p-tau Ser356 is associated with Alzheimer’s disease pathology and is lowered in brain slice cultures using the NUAK inhibitor WZ4003	9
Pituitary neuroendocrine tumors with PIT1/SF1 co-expression show distinct clinicopathological and molecular features	9
Molecular classification and outcome of children with rare CNS embryonal tumors: results from St. Jude Children’s Research Hospital including the multi-center SJYC07 and SJMB03 clinical trials	9
Proteomic identification of select protein variants of the SNARE interactome associated with cognitive reserve in a large community sample	9
Loss of the heterogeneous expression of flippase ATP11B leads to cerebral small vessel disease in a normotensive rat model	9
Genetic and epigenetic characterization of posterior pituitary tumors	9
Strain diversity in neurodegenerative disease: an argument for a personalized medicine approach to diagnosis and treatment	9
Comprehensive proteomics of CSF, plasma, and urine identify DDC and other biomarkers of early Parkinson’s disease	9
TREM2 risk variants are associated with atypical Alzheimer’s disease	9
The contribution of β-amyloid, Tau and α-synuclein to blood–brain barrier damage in neurodegenerative disorders	9
Galectin-3 shapes toxic alpha-synuclein strains in Parkinson’s disease	9
Fatal encephalitis caused by Newcastle disease virus in a child	9
AMFR dysfunction causes autosomal recessive spastic paraplegia in human that is amenable to statin treatment in a preclinical model	8
Blood-based Aβ42 increases in the earliest pre-pathological stage before decreasing with progressive amyloid pathology in preclinical models and human subjects: opening new avenues for prevention	8
Dysregulation of astrocytic Ca2+ signaling and gliotransmitter release in mouse models of α-synucleinopathies	8