Acta Dermato-Venereologica

Article	Citations
Pruritus in Keloid Scars: Mechanisms and Treatments	41
Long-term Safety of Secukinumab Over Five Years in Patients with Moderate-to-severe Plaque Psoriasis, Psoriatic Arthritis and Ankylosing Spondylitis: Update on Integrated Pooled Clinical Trial and Pos	40
Common Fundamentals of Psoriasis and Depression	32
Real-life Effectiveness and Safety of Risankizumab in Moderate-to-severe Plaque Psoriasis: A 40-week Multicentric Retrospective Study	29
Predictors of Response to Biologics in Patients with Moderate-to-severe Psoriasis: A Danish Nationwide Cohort Study	24
Perceived Stigmatization among Dermatological Outpatients Compared with Controls: An Observational Multicentre Study in 17 European Countries	24
Sleep Disorders and Psoriasis: An Update	21
Itch and Janus Kinase Inhibitors	20
Prevalence and Odds of Anxiety Disorders and Anxiety Symptoms in Children and Adults with Psoriasis: Systematic Review and Meta-analysi	17
Treatment of Atopic Dermatitis with Baricitinib: First Real-life Experience	17
Prevalence and Severity of Hand Eczema in the Dutch General Population: A Cross-sectional, Questionnaire Study within the Lifelines Cohort Study	17
Quality of Life and Psychopathology in Lichen Planus: A Neglected Disease Burden	17
Systematic Review and Meta-analysis of the Association Between Metabolic Syndrome and Androgenetic Alopecia	16
Comparative Efficacy and Safety of Monoclonal Antibodies and Janus Kinase Inhibitors in Moderate-to-severe Atopic Dermatitis: A Systematic Review and Meta-analysis	16
Factors Associated with Affective Symptoms and Quality of Life in Patients with Atopic Dermatitis	15
Guselkumab Treatment Outcomes and Persistence in a Nationwide Real-world Cohort of Patients with Plaque Psoriasis	14
Itching in Atopic Dermatitis: Patient- and Physician-reported Outcomes in the German Atopic Dermatitis Registry TREATgermany	14
Risk of Reactivation of Latent Tuberculosis in Psoriasis Patients on Biologic Therapies: A Retrospective Cohort from a Tertiary Care Centre in Northern Italy	14
Safety of Brodalumab in Plaque Psoriasis: Integrated Pooled Data from Five Clinical Trials	13
Comparative Efficacy and Safety of Janus Kinase Inhibitors Used in Alopecia Areata: A Systematic Review and Meta-analysis	13
Lichen Simplex Chronicus Itch: An Update	13
Physician-reported Clinical Unmet Needs, Burden and Treatment Patterns of Paediatric Psoriasis Patients: A US and EU Real-world Evidence Study	12
Risk Factors and Rate of Recurrence after Mohs Surgery in Basal Cell and Squamous Cell Carcinomas: A Nationwide Prospective Cohort (REGESMOHS, Spanish Registry of Mohs Surgery)	12
Incidence Rate of Hand Eczema in Different Occupations: A Systematic Review and Meta-analysis	11
Chronic Use of Hydrochlorothiazide and Risk of Skin Cancer in Caucasian Adults: A PharmLines Initiative Inception Cohort Study	10

Development of Nodular Lesions after Dupilumab Therapy in Erythrodermic Mycosis Fungoides with Interleukin-13 Receptor alpha2 Expression	10
Chronic Urticaria: A Swedish Registry-based Cohort Study on Population, Comorbidities and Treatment Characteristics	10
Rapid Enlargement of Vitiligo Vulgaris after Initiation of Dupilumab for Atopic Dermatitis: A Case Report	10
Association of Chronic Urticaria with Psychological Distress: A Multicentre Cross-sectional Study	10
Efficacy and Safety of Risankizumab in Hidradenitis Suppurativa: A Case Series	10
Leukaemia Cutis: Clinical Features and Outcomes of 56 Patients	10
Daily Practice Experience of Baricitinib Treatment for Patients with Difficult-to-Treat Atopic Dermatitis: Results from the BioDay Registry	10
Involvement of Sensory Neurone-TRPV4 in Acute and Chronic Itch Behaviours	10
Diagnostic Accuracy of Trichoscopy in Trichotillomania: A Systematic Review	10
Activation of NLRP3 Inflammasome in the Skin of Patients with Systemic and Cutaneous Lupus Erythematosus	10
Effectiveness of Upadacitinib in Patients with Atopic Dermatitis including those with Inadequate Response to Dupilumab and/or Baricitinib: Results from the BioDay Registry	10
Dupilumab Provides Rapid and Sustained Clinically Meaningful Responses in Adults with Moderate-to-severe Atopic Dermatitis	9
The Treat-to-Target Project in Atopic Dermatitis: One Year On	9
Use of Large Language Models: Editorial Comments	9
Direct Comparison of Real-world Effectiveness of Biologics for Psoriasis using Absolute and Relative Psoriasis Area and Severity Index Scores in a Prospective Multicentre Cohort	9
Type D Personality Is Associated with Poorer Quality of Life in Patients with Chronic Spontaneous Urticaria: A Cross-sectional Study	9
Identification of Risk Factors for Dupilumab-associated Ocular Surface Disease in Patients with Atopic Dermatitis	9
Real-World Treatment Patterns and Treatment Benefits among Adult Patients with Atopic Dermatitis: Results from the Atopic Dermatitis Patient Satisfaction and Unmet Need Survey	9
Safety and Efficacy of Topical Calcineurin Inhibitors in the Treatment of Facial and Genital Psoriasis: A Systematic Review	8
Adjuvant Anti-PD-1 Antibody Therapy for Advanced Melanoma: A Multicentre Study of 78 Japanese Cases	8
Body Composition, Cardiometabolic Risk Factors and Comorbidities in Psoriasis and the Effect of HLA-C*06:02 Status: The HUNT Study, Norway	8
Dupilumab Significantly Reduces Symptoms of Prurigo Nodularis and Depression: A Case Series	8
Local Hyperthermia Versus Cryotherapy for Treatment of Plantar Warts: A Prospective Multi-centre Non-randomized Concurrent Controlled Clinical Trial	8
Relationship Between Pemphigus Vulgaris Severity and PCR-positive Herpes Simplex Virus	8
Hidradenitis Suppurativa Prevalence in Nuuk, Greenland: Physician Validation of a Hidradenitis Suppurativa Questionnaire in a Greenlandic Setting	8
Alopecia Areata as a Proximal Risk Factor for the Development of Comorbid Depression: A Population-based Study	8
Toxic Epidermal Necrolysis Caused by Apalutamide: A Case Report of Treatment Using Etanercept with Conventional Steroid Therapy	8
Age-dependent Distribution of Atopic Dermatitis in Primary Care: A Nationwide Population-based Study from Finland	8
Burden of Sensitive Skin (BoSS) Questionnaire and Current Perception Threshold: Use as Diagnostic Tools for Sensitive Skin Syndrome	8
Increased Risk of Dementia in Patients with Atopic Dermatitis: A Nationwide Population-Based Cohort Study	7
Effect of Disease Severity on Comorbid Conditions in Atopic Dermatitis: Nationwide Registry-Based Investigation in Finnish Adults	7
Tofacitinib for Treatment of Alopecia Areata: Real-world Evidence and Factors Associated with Therapeutic Response	7
Sustained Resolution of Nail Psoriasis Through 5 Years with Ixekizumab: A Post-Hoc analysis from UNCOVER-3	7
Patch Testing with Propolis of Different Geographical Origins in a Baseline Series	7
Long-term Remission of Atopic Dermatitis after Discontinuation of Dupilumab	7
Chitinase-3-like Protein 1 (YKL-40): A New Biomarker of Inflammation in Pyoderma Gangrenosum	7
Systemic Sarcoidosis with Cutaneous Tattoo Involvement Following COVID-19 Vaccination	7
Effects of Early Emollient Use in Children at High Risk of Atopic Dermatitis: A German Pilot Study	7
Global Risk of Bacterial Skin Infections and Herpesviridae Infections with Ustekinumab, Secukinumab, and Tumour Necrosis Factor-alpha Inhibitors: Spontaneous Reports of Adverse Drug Reactions from the	7
Comorbidity of Dermal and Cardiovascular Disorders with Lichen Sclerosus: A Case-control Study	7
Differentiation Between Benign and Malignant Pigmented Skin Tumours Using Bedside Diagnostic Imaging Technologies: A Pilot Study	7
Pleomorphic Onychomatricoma: A Mimicker of Malignancy	7
Effect of Stabilized Hypochlorous Acid on Re-epithelialization and Bacterial Bioburden in Acute Wounds: A Randomized Controlled Trial in Healthy Volunteers	7
Smoking is an Independent Marker of Poor Prognosis in Cutaneous Melanoma	7
Epidemiology, Comorbidity and Risk Factors for Psoriatic Arthritis: A Health Insurance Claims Database Analysis	7
Dupilumab-induced Acute Generalized Exanthematous Pustulosis in a 17-year-old Female Chinese Patient with Atopic Dermatitis	6
Interobserver Agreement on Dermoscopic Features and their Associations with In Situ and Invasive Cutaneous Melanomas	6
Biomarkers of Skin Graft Healing in Venous Leg Ulcers	6
Rapid and Sustained Effect of Dupilumab on Work Productivity in Patients with Difficult-to-treat Atopic Dermatitis: Results from the Dutch BioDay Registry	6
Sonidegib in the Treatment of Locally Advanced Basal Cell Carcinoma: A Retrospective Study	6

The Potential of Instagram to Reduce Stigmatization of People with Psoriasis: A Randomized Controlled Pilot Study	6
Differences in Occurrence, Risk Factors and Severity of Early-onset Atopic Dermatitis among Preterm and Term Children	6
Acute Generalized Exanthematous Pustulosis in Close Temporal Association with mRNA-1273 Vaccine	6
Updated Role of High-frequency Ultrasound in Assessing Dermatological Manifestations in Autoimmune Skin Diseases	6
Severe and ChRonic Atopic dermatitis Treatment CoHort (SCRATCH): A Danish Real-world Evidence Atopic Dermatitis Treatment Registry	6
Psychological Stress in Parents of Children with Atopic Dermatitis: A Cross-sectional Study from the Korea National Health and Nutrition Examination Survey	6
Impact of Etanercept on Vitamin D Status and Vitamin D-binding Protein in Bio-naïve Patients with Psoriasis	6
Incidence, Prevalence, and Mortality of People with Psoriasis and Psoriatic Arthritis in Taiwan: A Nationwide Cohort Study	6
Real-world Methotrexate Use in a Prospective Cohort of Paediatric Patients with Plaque Psoriasis: Effectiveness, Adverse Events and Folic Acid Regimen	6
Real-world Experience of Abrocitinib Treatment in Patients with Atopic Dermatitis and Hand Eczema: Up to 28-week Results from the BioDay Registry	6
Age-related Differences in Tumour Characteristics and Prognostic Factors for Disease Progression in Cutaneous Squamous Cell Carcinoma of the Head and Neck	6
The Atopic Dermatitis Control Tool: A High-Performance Tool for Optimal Support	6
Secukinumab Exhibits Sustained and Stable Response in Patients with Moderate-to-Severe Psoriasis: Results from the SUPREME Study	6
Drug Survival of Anti Interleukin-17 and Interleukin -23 Agents after Adalimumab Failure in Hidradenitis Suppurativa: A Pilot Study	6
Neuroimmune Mediators of Pruritus in Hispanic Scalp Psoriatic Itch	6
Association between Pruritus and Psychosocial Well-being: A Population-based Study among 6,809 Subjects	6
Bone Metabolism in Patients with Hidradenitis Suppurativa: A Case-control Study	5
Ruxolitinib, a JAK1/2 Inhibitor as Treatment for Paraneoplastic Pemphigus: A Case Report	5
Capillary Malformation-arteriovenous Malformation Type 2: A Case Report and Review	5
Real-World Treatment Patterns among Patients with Alopecia Areata in the USA: A Retrospective Claims Analysis	5
Serum Interleukin-13 and Caspase 8 are Elevated in Prurigo Nodularis	5
Drug-induced Delusional Infestation	5
Long-term Outcome of Chilblains Associated with SARS-CoV-2	5
Psoriasis/Psoriatic Arthritis Patients’ Long-term Treatment Patterns and Adherence to Systemic Treatments Monitoring Recommendations	5
Use of Pegylated Interferon Alpha-2a in Cutaneous T-cell Lymphoma: A Retrospective Case Collection	5
Discovery of Psoriatic Arthritis in Psoriasis Patients for Early Rheumatological Referral (DAPPER) Study: A Prospective Observational Cohort	5
Skin Microbiome in Patients with Hand Eczema and Healthy Controls: A Three-week Prospective Study	5
Incidence and Prevalence of 73 Different Genodermatoses: A Nationwide Study in Sweden	5
Successful Treatment of Paediatric Morphea with Tofacitinib	5
Prevalence and Associated Factors of Alexithymia in Patients with Hidradenitis Suppurativa: A Cross-sectional Study	5
Severe Scabies: A French Multi-centre Study Involving 95 Patients with Crusted and Profuse Disease and Review of the Literature	5
Ablative Fractional Laser-assisted Low-irradiance Photodynamic Therapy for Treatment of Actinic Keratoses in Organ Transplant Recipients: A Prospective, Randomized, Intraindividual Controlled Trial	5
The Importance of Assessing Burning and Stinging when Managing Rosacea: A Review	5
Changes in Infection Prevention Practices and Occurrence of Skin Symptoms among Healthcare Workers, Cleaners and Day-care Workers in Norway during the COVID-19 Pandemic	5
Serum Cytokeratin 18 as a Metastatic and Therapeutic Marker for Extramammary Paget’s Disease	5
Efficacy of Treatments for Cholestatic Pruritus: A Systemic Review and Meta-analysis	5
Cardiovascular Screening Practices and Statin Prescription Habits in Patients with Psoriasis among Dermatologists, Rheumatologists and Primary Care Physicians	5
A Structured Intervention for Medical Students Significantly Improves Awareness of Stigmatisation in Visible Chronic Skin Diseases: A Randomised Controlled Trial	5
A Comparative Analysis of the Predictors, Extent and Impacts of Self-stigma in Patients with Psoriasis and Atopic Dermatitis	5
Upadacitinib for Successful Treatment of Alopecia Universalis in a Child: A Case Report and Literature Review	5
Dupilumab Provides Rapid and Sustained Improvement in SCORing Atopic Dermatitis Outcomes in Paediatric Patients with Atopic Dermatitis	5
Diagnostic Value of Optical Coherence Tomography Image Features for Diagnosis of Basal Cell Carcinoma	5
Chlormethine Gel is Efficient and Safe in Mycosis Fungoides Skin Lesions	5
Determinants of 25-hydroxyvitamin D Status in a Cutaneous Melanoma Population	5
Suicide and Suicidality in Children and Adolescents with Chronic Skin Disorders: A Systematic Review	5
The Impact of Systemic Treatment of Atopic Dermatitis on Depressive Symptoms: A Prospective Clinical Cohort Study	5
Longitudinal Evaluation of Biomarkers in Wound Fluids from Venous Leg Ulcers and Split-thickness Skin Graft Donor Site Wounds Treated with a Protease-modulating Wound Dressing	5
A Retrospective Study of 105 Patients with Elastolytic Giant Cell Granuloma and a Proposal for a New Clinical Classification	5
Impact of COVID-19 Pandemic on the Incidence of Sexually Transmitted Infections in Northern Finland in 2019 to 2022	5
Psychopathology Associated with Chronic Pruritus: A Systematic Review	5
Successful Treatment of Atopic Dermatitis with Dupilumab in a Patient with Non-Hodgkin’s Lymphoma	5
Evaluating the Effectiveness of Intranasal Butorphanol in Reducing Chronic Itch	5
Evolution of Drug Survival with Biological Agents and Apremilast Between 2012 and 2018 in Patients with Psoriasis from the PsoBioTeq Cohort	4
Nonsense Suppression Therapy: An Emerging Treatment for Hereditary Skin Diseases	4
YAP1-NUTM1 Gene Fusion in Eccrine Porocarcinoma with Late Metastatic Recurrence: A Case Report	4
Antipruritic Effect of Topical Acetaminophen Gel in Histaminergic and Non-histaminergic Itch Provocation: A Double-blind, Vehicle-controlled Pilot Study	4
Risk of Non-cutaneous Cancers in Individuals with Basal Cell Carcinoma: A Population-based Cohort Study	4
Real-world Data Reveal Long Drug Survival for Guselkumab in Patients with Plaque Psoriasis	4
Variable Outcome of Immunotherapy in Advanced Multiple Cutaneous Squamous Cell Carcinomas in Two Patients with Recessive Dystrophic Epidermolysis Bullosa	4
Characteristics of Patients with Generalized Pustular Psoriasis and Psoriatic Arthritis: A Retrospective Cohort Study	4
Hidradenitis Suppurativa International Online Community: Patient Characteristics and a Novel Model of Treatment Effectiveness	4
Scarring Alopecia Under Immune Checkpoint Blockade: a Report of Three Cases	4
Out-of-Pocket Costs in Alopecia Areata: A Cross-Sectional Study in German-speaking Countries	4
Dermatological Conditions Inducing Acute and Chronic Pain	4
Beyond Anxiety and Depression: Loneliness and Psychiatric Disorders in Adults with Atopic Dermatitis	4
Similar Levels of Disease Severity Correspond to a Greater Burden of Illness in Women Compared with Men with Hidradenitis Suppurativa	4
Prevalence, Spectrum and Clinical Implications of Malignancies in Patients with Bullous Pemphigoid	4
Psoriatic Insomnia: A Subjective and Objective Sleep Evaluation	4
Truncal Acne in Adolescents and Young Adults: Self-reported Perception	4
Impact of Atopic Dermatitis on Patients and their Partners	4
Real-life Use of Bexarotene for T-cell Cutaneous Lymphoma Management: Efficacy and Tolerance with Low Doses	4
Unmet Needs in the Management of Moderate-to-Severe Psoriasis in Spain: A Multidimensional Evaluation	4
Malassezia restricta-mediated Lipoperoxidation: A Novel Trigger in Dandruff	4
Overall Impairment of Quality of Life in Japanese Patients with Hidradenitis Suppurativa: Comparison with National Standard	4
Impact of Type 1 Versus Type 2 Diabetes on Developing Herpes Zoster and Post-herpetic Neuralgia: A Population-based Cohort Study	4
Acute Itch Induces Attentional Avoidance of Itch-related Information	4
Living with Atopic Dermatitis as a Young Adult in Relation to Health-related Quality of Life and Healthcare Contacts: A Population-based Study	4
miRNA Signature in Early-stage Mycosis Fungoides	4
Real-world Treatment Patterns and Outcomes with Systemic Therapies in Unresectable Locally Advanced and Metastatic Cutaneous Squamous Cell Carcinoma in Germany	4
Acneiform Lesions but not Acne after Treatment with Janus Kinase Inhibitors: Diagnosis and Management of Janus Kinase-acne	4

Type I Interferon Signature in Chilblains Following SARS-CoV-2 mRNA Vaccine: A Case Report	4
Clinically Meaningful Responses to Dupilumab Among Children Aged 6 Months to 5 Years with Moderate-to-severe Atopic Dermatitis who did Not Achieve Clear or Almost Clear Skin According to the Investiga	3
Differential Immunoexpression of BRAF/V600E, Senescence Markers, PTEN, and T-type Calcium Channels in Acquired Naevi According to their Histopathological and Dermoscopic Classification	3
Characteristics, Natural Course and Treatment of Intramuscular Capillary-type Haemangioma: A Systematic Literature Review	3
Eczema-related Web Search Data in Sweden: Investigating Search Patterns and the Influence of Weather	3
Correlation between Dermatology Life Quality Index and Psoriasis Area and Severity Index in Patients with Psoriasis: A Cross-sectional Global Healthcare Study on Psoriasis	3
Dermato-neuro Syndrome after COVID-19 Vaccination in a Patient with Scleromyxoedema Previously Controlled with Bortezomib and Intravenous Immunoglobulins	3
Artificial Nails and Long-lasting Nail Polish in Danish Hairdressers: Self-use, Occupational Exposure and Related Eczema	3
Quality of Life in Danish Blood Donors Treated for Superficial Fungal Infections	3
Impact of Chronic Kidney Disease Severity on the Risk of Prurigo Nodularis: A Population-Based Cohort Study	3
Characterization of Classical Flexural and Nummular Forms of Atopic Dermatitis in Childhood with Regard to Anamnestic, Clinical and Epidermal Barrier Aspects	3
Self-reported Versus Physician-reported Severity of Chronic Hand Eczema: Concordance Analysis Based on Data from the German Chronic Hand Eczema Patient Long-Term Management Registry	3
Economic and Humanistic Burden in Paediatric Patients with Atopic Dermatitis	3
Efficacy and Safety of Tildrakizumab in Older Patients: Pooled Analyses of Two Randomized Phase III Clinical Trials (reSURFACE 1 and reSURFACE 2) Through 244 Weeks	3
High Expression of IKZF2 in Malignant T Cells Promotes Disease Progression in Cutaneous T Cell Lymphoma	3
Risk of Skin Cancer and Actinic Keratosis in Patients with Rosacea: A Nationwide Population-based Cohort Study	3
Association Between Diet and Acne Severity: A Cross-sectional Study in Thai Adolescents and Adults	3
Evaluation of Melanoma Thickness with Clinical Close-up and Dermoscopic Images Using a Convolutional Neural Network	3
Non-pegylated and Pegylated Interferon Alpha-2a in Cutaneous T-cell Lymphoma and the Risk of Severe Ocular Side-effects	3
Recurrent Alterations in the MAPK pathway in Sporadic Pyogenic Granuloma of Childhood	3
Frontal Fibrosing Alopecia and Sunscreen Use: A Cross-sectional Study of Actinic Damage	3
Deep Learning-based Trichoscopic Image Analysis and Quantitative Model for Predicting Basic and Specific Classification in Male Androgenetic Alopecia	3
A New Pathogenic Variant of the RTEL1 Gene and Dyskeratosis Congenita: A Dermatological View	3
Sex-differences in Gluten-free Dietary Adherence and Clinical Symptoms in Patients with Long-term Treated Dermatitis Herpetiformis	3
Psoriatic Skin Lesions after Apalutamide Treatment	3
Expert Recommendations on Facilitating Personalized Approaches to Long-term Management of Actinic Keratosis: The Personalizing Actinic Keratosis Treatment (PAKT) Project	3
A Case Series of 18 Congenital Haemangiomas: Clinical, Histological and Ultrasound Features, and their Relationship with Complications and Atypical Behaviour	3
Effectiveness of Tofacitinib in Pre-adolescent Alopecia Areata: A Retrospective Case Series and Literature Review	3
Safety Assessment of Conventional and Biological Systemic Therapy in Older Adults with Psoriasis, a Real-world Multicentre Cohort Study	3
Altered Maturation of the Skin Microbiome in Infants with Atopic Dermatitis	3
Treatment of Digital Ulcers and Reflux Oesophagitis in a Patient with Systemic Sclerosis: Increased Risk of Hepatotoxicity due to a Potential Drug-drug Interaction Between Bosentan and Vonoprazan	3
Prolonged Sick Leave Before and After Diagnosis of Generalized Pustular Psoriasis: A Swedish Population-based Register Study	3
Role of Mast Cells in the Pathogenesis of Pruritus in Mastocytosis	3
Aesthetic Outcome of Propranolol vs Atenolol Treatment of Children with Infantile Haemangioma	3
A Nationwide Observational Study of Chlamydia trachomatis Infections in Denmark during the COVID-19 Pandemic	3
Blistering Papulosquamous Erythema with Arthralgia: A Quiz	3
Hyperhidrosis Comorbidities and Treatments: A Register-based Study among 511 Subjects	3
Treatment Patterns and Clinical Outcomes of Chronic Urticaria: Two-year Follow-up Results from the Scandinavian AWARE Study	3
Prevalence and Increase over Time of Twelve Self-reported Skin Symptoms: Data from Two Representative Samples from 1998 and 2015	3
Atezolizumab Plus Bevacizumab-induced Recalcitrant Pyoderma Gangrenosum Treated with Baricitinib: A Case Report	3
Development of a Conceptual Framework for a Patient-Reported Impact of Dermatological Diseases (PRIDD) Measure: A Qualitative Concept Elicitation Study	3
Chilblain-like Lesions after COVID-19 Vaccination: A Case Series	3
Risk of Melanoma in Patients with Basal Cell Carcinoma: A Population-based Cohort Study	3
Type D Personality as a Marker of Poorer Quality of Life and Mood Status Disturbances in Patients with Skin Diseases: A Systematic Review	3
Purpuric Drug Eruption in a Patient with Atopic Dermatitis Treated with Dupilumab	3
Treatment Patterns among Patients with Atopic Dermatitis in Secondary Care: A National, Observational, Non-interventional, Retrospective Study in Sweden	3