Cell Reports

Papers
(The TQCC of Cell Reports is 20. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)
ArticleCitations
Tyzzerella nexilis strains enriched in mobile genetic elements are involved in progressive multiple sclerosis358
The architecture of silk-secreting organs during the final larval stage of silkworms revealed by single-nucleus and spatial transcriptomics310
PIX is an N-terminal delivery domain that defines a class of polymorphic T6SS effectors in Enterobacterales287
Cellular Importin-α3 Expression Dynamics in the Lung Regulate Antiviral Response Pathways against Influenza A Virus Infection251
Santa-maria is a glial phagocytic receptor that acts with SIMU to recognize and engulf apoptotic neurons251
CPSF1 inhibition promotes widespread use of intergenic polyadenylation sites and impairs glycolysis in prostate cancer cells227
Auditory discrimination learning differentially modulates neural representation in auditory cortex subregions and inter-areal connectivity216
Distinct TAM subset with cross-dressing capability determines the bifurcation of tumor immunity212
Sugar detection in 3D: Structure of an insect gustatory receptor175
Q&A with Hao Gu168
A synthetic chlorophagy receptor promotes plant fitness by mediating chloroplast microautophagy167
CD4+ T cells regulate sickness-induced anorexia and fat wasting during a chronic parasitic infection164
Deep ancestry of Bornean hunter-gatherers supports long-term local ancestry dynamics161
β1 integrin signaling governs necroptosis via the chromatin-remodeling factor CHD4158
MOF-mediated acetylation of SIRT6 disrupts SIRT6-FOXA2 interaction and represses SIRT6 tumor-suppressive function by upregulating ZEB2 in NSCLC149
Regionally defined proteomic profiles of human cerebral tissue and organoids reveal conserved molecular modules of neurodevelopment147
Chemical-induced epigenome resetting for regeneration program activation in human cells145
Atg15 is a vacuolar phospholipase that disintegrates organelle membranes143
Sugar-responsive inhibition of Myc-dependent ribosome biogenesis by Clockwork orange141
Pain hypersensitivity is dependent on autophagy protein Beclin 1 in males but not females140
Combinatorial Developmental Controls on Striatonigral Circuits139
Deneddylation of ribosomal proteins promotes synergy between MLN4924 and chemotherapy to elicit complete therapeutic responses134
Leave no sister behind134
Cdc48 influence on separase levels is independent of mitosis and suggests translational sensitivity of separase133
Distinct changes to hippocampal and medial entorhinal circuits emerge across the progression of cognitive deficits in epilepsy130
Regulation of RNA localization during oocyte maturation by dynamic RNA-ER association and remodeling of the ER130
Stereotyped goal-directed manifold dynamics in the insular cortex129
Secretory IgA in breast milk protects against asthma through modulation of the gut microbiota128
Genome-wide fetalization of enhancer architecture in heart disease122
DRD1 signaling modulates TrkB turnover and BDNF sensitivity in direct pathway striatal medium spiny neurons122
Rigid, bivalent CTLA-4 binding to CD80 is required to disrupt the cis CD80/PD-L1 interaction120
HuR promotes triglyceride synthesis and intestinal fat absorption119
In vivo partial cellular reprogramming enhances liver plasticity and regeneration119
Critical roles of the miR-17∼92 family in thymocyte development, leukemogenesis, and autoimmunity119
Cytoskeletal activation of NHE1 regulates mechanosensitive cell volume adaptation and proliferation118
The balance between IFN-γ and ERK/MAPK signaling activities ensures lifelong maintenance of intestinal stem cells117
Coordinated expression of retained introns and poison exons in renal cell carcinoma116
Structure of a SARS-CoV-2 spike S2 subunit in a pre-fusion, open conformation115
A trans-kingdom T6SS RNase effector targeting both prokaryotic and host cells for pathogenesis114
Genome restructuring and lineage diversification of Cryptococcus neoformans during chronic infection of human hosts112
Progenitor-like cells contributing to cellular heterogeneity in the nucleus pulposus are lost in intervertebral disc degeneration111
PFKFB3 activates CAD to enhance de novo pyrimidine synthesis for cell growth111
Extracellular vesicle-mediated trafficking of molecular cues during human brain development109
Exploring the pan-cancer landscape of posttranscriptional regulation109
Very-long-chain fatty acids are crucial to neuronal polarity by providing sphingolipids to lipid rafts105
Activity-dependent PI4P synthesis by PI4KIIIα regulates long-term synaptic potentiation104
CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistance103
The m C methyltransferase NSUN2 promotes progression of acute myeloid leukemia by regulating serine metabolism103
Structural basis of ligand specificity and channel activation in an insect gustatory receptor103
Q&A with Bin Cao103
The histone chaperone ANP32B regulates chromatin incorporation of the atypical human histone variant macroH2A102
Motile cilia modulate neuronal and astroglial activity in the zebrafish larval brain101
Unique potential of immature adult-born neurons for the remodeling of CA3 spatial maps101
The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression100
MYB68 regulates radial endodermal differentiation and suberin patterning99
Chlorophyll biosynthesis under the control of arginine metabolism99
Mechanosensitive Notch-Dll4 and Klf2-Wnt9 signaling pathways intersect in guiding valvulogenesis in zebrafish98
The CD27/CD70 pathway negatively regulates visceral adipose tissue-resident Th2 cells and controls metabolic homeostasis97
An ERK5-PFKFB3 axis regulates glycolysis and represents a therapeutic vulnerability in pediatric diffuse midline glioma96
Axonal mRNA binding of hnRNP A/B is crucial for axon targeting and maturation of olfactory sensory neurons96
HNF4A modulates glucocorticoid action in the liver96
Mapping the evolution of T cell states during response and resistance to adoptive cellular therapy96
The medial entorhinal cortex encodes multisensory spatial information94
Chronic hypoxia stabilizes 3βHSD1 via autophagy suppression93
A cell-type-specific alternative splicing regulator shapes synapse properties in a trans-synaptic manner93
Optogenetic silencing of medial septal GABAergic neurons disrupts grid cell spatial and temporal coding in the medial entorhinal cortex93
Synergistic hyperactivation of both mTORC1 and mTORC2 underlies the neural abnormalities of PTEN-deficient human neurons and cortical organoids93
A cancer-associated METTL14 mutation induces aberrant m6A modification, affecting tumor growth92
TGF-β Determines the Pro-migratory Potential of bFGF Signaling in Medulloblastoma91
Association of B cell profile and receptor repertoire with the progression of Alzheimer’s disease91
PAMless SpRY exhibits a preference for the seed region for efficient targeting91
Single-cell RNA-seq analysis identifies the atlas of lymph fluid and reveals a sepsis-related T cell subset90
Gamma synchronization between the medial temporal lobe and medial frontal cortex for goal-directed visual attention in humans90
EKLF/Klf1 regulates erythroid transcription by its pioneering activity and selective control of RNA Pol II pause-release89
Rhabdomyosarcoma fusion oncoprotein initially pioneers a neural signature in vivo89
Cortical mechanisms of visual brightness89
Multimodal CRISPR screens uncover DDX39B as a global repressor of A-to-I RNA editing89
Single-cell analysis reveals changes in BCG vaccine-injected mice modeling tuberculous meningitis brain infection88
Gestationally dependent immune organization at the maternal-fetal interface88
Direct type I interferon signaling in hepatocytes controls malaria88
MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis88
Acetylation-dependent regulation of BRAF oncogenic function88
A conserved switch to less catalytically active Polycomb repressive complexes in non-dividing cells87
Length-dependent poleward flux of sister kinetochore fibers promotes chromosome alignment87
53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication86
Endophytic mycobiont provides growth benefits via a phenylpropanoid-auxin axis in host plants86
A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors86
A type III-Dv CRISPR-Cas system is controlled by the transcription factor RpaB and interacts with the DEAD-box RNA helicase CrhR85
Gasdermin D restricts anti-tumor immunity during PD-L1 checkpoint blockade85
Salmonella enterica serovar Typhimurium uses anaerobic respiration to overcome propionate-mediated colonization resistance85
Potentiation of cholinergic and corticofugal inputs to the lateral amygdala in threat learning85
SoxD genes are required for adult neural stem cell activation85
Identifying genetic determinants of Streptococcus pyogenes-host interactions in a murine intact skin infection model84
Compartmentalized PGRP expression along the dipteran Bactrocera dorsalis gut forms a zone of protection for symbiotic bacteria84
Mitophagy antagonism by ZIKV reveals Ajuba as a regulator of PINK1 signaling, PKR-dependent inflammation, and viral invasion of tissues84
SLC38A5 aggravates DC-mediated psoriasiform skin inflammation via potentiating lysosomal acidification84
A molecular pathway for cancer cachexia-induced muscle atrophy revealed at single-nucleus resolution83
Mitochondrial cristae architecture protects against mtDNA release and inflammation83
AMPK-PERK axis represses oxidative metabolism and enhances apoptotic priming of mitochondria in acute myeloid leukemia83
Organization of hippocampal CA3 into correlated cell assemblies supports a stable spatial code83
The T cell receptor sequence influences the likelihood of T cell memory formation82
Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins82
LKB1 prevents ILC2 exhaustion to enhance antitumor immunity82
The OsbHLH002/OsICE1-OSH1 module orchestrates secondary cell wall formation in rice82
PCDH12 loss results in premature neuronal differentiation and impeded migration in a cortical organoid model81
The Parkinson’s-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F181
APOE4 drives inflammation in human astrocytes via TAGLN3 repression and NF-κB activation81
Phosphoproteomic profiling of influenza virus entry reveals infection-triggered filopodia induction counteracted by dynamic cortactin phosphorylation80
The human placenta shapes the phenotype of decidual macrophages80
Single-cell transcriptome profiling and chromatin accessibility reveal an exhausted regulatory CD4+ T cell subset in systemic lupus erythematosus80
Modification of histidine repeat proteins by inorganic polyphosphate80
Spatiotemporal patterns of neuronal subtype genesis suggest hierarchical development of retinal diversity79
EZH2 inhibition mitigates HIV immune evasion, reduces reservoir formation, and promotes skewing of CD8+ T cells toward less-exhausted phenotypes79
Hierarchical behavioral analysis framework as a platform for standardized quantitative identification of behaviors79
Control of Foxp3 induction and maintenance by sequential histone acetylation and DNA demethylation79
Engineering of dendritic cell bispecific extracellular vesicles for tumor-targeting immunotherapy79
Food-induced dopamine signaling in AgRP neurons promotes feeding79
Long-lasting antibody B-cell responses to SARS-CoV-2 three years after the onset of the pandemic78
An Aurora kinase A-BOD1L1-PP2A B56 axis promotes chromosome segregation fidelity78
The nuclear Argonaute HRDE-1 directs target gene re-localization and shuttles to nuage to promote small RNA-mediated inherited silencing78
Modulation of central synapse remodeling after remote peripheral injuries by the CCL2-CCR2 axis and microglia78
DNA replication is highly resilient and persistent under the challenge of mild replication stress77
Direction selectivity of inhibitory interneurons in mouse barrel cortex differs between interneuron subtypes77
An unconventional VH1-2 antibody tolerates escape mutations and shows an antigenic hotspot on SARS-CoV-2 spike77
Supercoiling-mediated feedback rapidly couples and tunes transcription77
SRSF3-mediated regulation of N6-methyladenosine modification-related lncRNA ANRIL splicing promotes resistance of pancreatic cancer to gemcitabine77
Multi-level functional genomics reveals molecular and cellular oncogenicity of patient-based 3′ untranslated region mutations76
Cross-species communication via agr controls phage susceptibility in Staphylococcus aureus76
CD84 as a therapeutic target for breaking immune tolerance in triple-negative breast cancer76
PRRC2B modulates oligodendrocyte progenitor cell development and myelination by stabilizing Sox2 mRNA76
Intercellular extrachromosomal DNA copy-number heterogeneity drives neuroblastoma cell state diversity75
Tumor-derived Jagged1 promotes cancer progression through immune evasion75
Piezo1 senses hyphae and initiates host defense against pathogenic fungi74
FTY720 requires vitamin B12-TCN2-CD320 signaling in astrocytes to reduce disease in an animal model of multiple sclerosis74
Single cell approaches define neural stem cell niches and identify microglial ligands that can enhance precursor-mediated oligodendrogenesis74
Vibrio parahaemolyticus prey targeting requires autoproteolysis-triggered dimerization of the type VI secretion system effector RhsP73
Systematic analysis of human antibody response to ebolavirus glycoprotein shows high prevalence of neutralizing public clonotypes73
FoxM1 coordinates cell division, protein synthesis, and mitochondrial activity in a subset of β cells during acute metabolic stress73
The absence of telomerase leads to immune response and tumor regression in zebrafish melanoma73
Structural basis for high-order complex of SARNP and DDX39B to facilitate mRNP assembly73
Fibroblast diversification is an embryonic process dependent on muscle contraction72
Angiogenesis in the mature mouse cortex is governed in a regional- and Notch1-dependent manner72
Organization of Purkinje cell development by neuronal MEGF11 in cerebellar granule cells72
Loss of neuronal heterogeneity in epileptogenic human tissue impairs network resilience to sudden changes in synchrony72
Enforced activation of the CREB/KDM2B axis prevents alcohol-induced embryonic developmental delay71
A synaptic molecular dependency network in knockdown of autism- and schizophrenia-associated genes revealed by multiplexed imaging71
Failure of digit tip regeneration in the absence of Lmx1b suggests Lmx1b functions disparate from dorsoventral polarity71
Development of pial collaterals by extension of pre-existing artery tips71
High plasticity of ribosomal DNA organization in budding yeast70
OCIAD1 and prohibitins regulate the stability of the TIM23 protein translocase70
Periostin deficiency reduces PD-1+ tumor-associated macrophage infiltration and enhances anti-PD-1 efficacy in colorectal cancer70
Memory trace imbalance in reinforcement and punishment systems can reinforce implicit choices leading to obsessive-compulsive behavior69
Protein nanoparticle vaccines induce potent neutralizing antibody responses against MERS-CoV69
Neutralization fingerprinting technology for characterizing polyclonal antibody responses to dengue vaccines69
A robot-rodent interaction arena with adjustable spatial complexity for ethologically relevant behavioral studies69
Actin-dependent astrocytic infiltration is a key step for axon defasciculation during remodeling69
Laminar mechanisms of saccadic suppression in primate visual cortex68
Cell context-dependent CFI-1/ARID3 functions control neuronal terminal differentiation68
piRNA-guided intron removal from pre-mRNAs regulates density-dependent reproductive strategy68
Defects in CYB5A and CYB5B impact sterol-C4 oxidation in cholesterol biosynthesis and demonstrate regulatory roles of dimethyl sterols68
Coupling to Pam16 differentially controls the dual role of Pam18 in protein import and respiratory chain formation67
Amino acids in cancer: Understanding metabolic plasticity and divergence for better therapeutic approaches67
Mitochondrial fusion and cristae reorganization facilitate acquisition of cardiomyocyte identity during reprogramming of murine fibroblasts67
Single-cell atlas of craniogenesis uncovers SOXC-dependent, highly proliferative, and myofibroblast-like osteodermal progenitors67
Upregulation of exosome secretion from tumor-associated macrophages plays a key role in the suppression of anti-tumor immunity66
Synaptic vesicle binding of α-synuclein is modulated by β- and γ-synucleins66
Insulin and serine metabolism as sex-specific hallmarks of Alzheimer’s disease in the human hippocampus66
PKM2 diverts glycolytic flux in dependence on mitochondrial one-carbon cycle66
FABP5 in skin macrophages mediates saturated fat-induced IL-1β signaling in psoriatic inflammation66
YTHDF2 suppresses the plasmablast genetic program and promotes germinal center formation66
SPT16 ubiquitylation by DCAF14-CRL4 regulates FACT binding to histones66
Evaluating the impact of age on immune checkpoint therapy biomarkers66
A vascular-associated fibroblastic cell controls pancreatic islet immunity66
NKp44/HLA-DP-dependent regulation of CD8 effector T cells by NK cells65
EWSR1 maintains centromere identity65
Epitopes in the capsular polysaccharide and the porin OmpK36 receptors are required for bacteriophage infection of Klebsiella pneumoniae65
HSPA8 dampens SCAP/INSIG split and SREBP activation by reducing PKR-mediated INSIG phosphorylation65
A secondary metabolite of Limosilactobacillus reuteri R2lc drives strain-specific pathology in a spontaneous mouse model of multiple sclerosis65
Elevating PLK1 overcomes BETi resistance in prostate cancer via triggering BRD4 phosphorylation-dependent degradation in mitosis65
Prenatal inflammation perturbs murine fetal hematopoietic development and causes persistent changes to postnatal immunity65
Accumulation of branched-chain amino acids reprograms glucose metabolism in CD8+ T cells with enhanced effector function and anti-tumor response65
Optogenetic activation of cortical microglia promotes neuronal activity and pain hypersensitivity64
Adenosine metabolized from extracellular ATP promotes type 2 immunity through triggering A2BAR signaling in intestinal epithelial cells64
Corticospinal neuron subpopulation-specific developmental genes prospectively indicate mature segmentally specific axon projection targeting64
Limiting Mrs2-dependent mitochondrial Mg2+ uptake induces metabolic programming in prolonged dietary stress64
EPH receptor tyrosine kinases phosphorylate the PAR-3 scaffold protein to modulate downstream signaling networks64
METTL3 regulates cartilage development and homeostasis by affecting Lats1 mRNA stability in an m6A-YTHDF2-dependent manner64
Metabolite-dependent m6A methylation driven by mechanotransduction-metabolism-epitranscriptomics axis promotes bone development and regeneration64
The histone deacetylase HDAC1 controls dendritic cell development and anti-tumor immunity64
RNF13 mediates pH- and Ca2+-dependent regulation of lysosomal positioning63
Highly mutated antibodies capable of neutralizing N276 glycan-deficient HIV after a single immunization with an Env trimer63
The mitotic ATR-Chk1 pathway promotes CDK1 activity for faithful chromosome segregation63
Transformation of an early-established motor circuit during maturation in zebrafish63
Identification of CNOT1-CCR4-NOT as a suppressor of 53BP1-p53-p21 signaling63
The spliceosome component Usp39 controls B cell development by regulating immunoglobulin gene rearrangement63
Automated live-cell single-molecule tracking in enteroid monolayers reveals transcription factor dynamics probing lineage-determining function62
Single-cell multiomics reveals the oscillatory dynamics of mRNA metabolism and chromatin accessibility during the cell cycle62
Structural insights into ligand recognition, selectivity, and activation of bombesin receptor subtype-362
Divergent sex-specific effects on a ketogenic diet: Male, but not female, mice exhibit oxidative stress and cellular senescence62
Histone acetyltransferase HAF2 associates with pyruvate dehydrogenase complex to control H3K14ac and H3K23ac in ethylene response62
A rice protein modulates endoplasmic reticulum homeostasis and coordinates with a transcription factor to initiate blast disease resistance62
Downregulation of nutrition sensor GCN2 in macrophages contributes to poor wound healing in diabetes62
Molecular landscape of sex- and modality-specific exercise adaptation in human skeletal muscle through large-scale multi-omics integration61
The soil microbiome modulates the sorghum root metabolome and cellular traits with a concomitant reduction of Striga infection61
The Chlamydia effector IncE employs two short linear motifs to reprogram host vesicle trafficking61
Mammalian milk glycomes: Connecting the dots between evolutionary conservation and biosynthetic pathways61
Astrocytes produce nitric oxide via nitrite reduction in mitochondria to regulate cerebral blood flow during brain hypoxia61
Laminar and dorsoventral organization of layer 1 interneuronal microcircuitry in superficial layers of the medial entorhinal cortex61
PGE2-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment61
Midbrain dopamine neurons signal phasic and ramping reward prediction error during goal-directed navigation61
Mitochondrial transplantation rescues Ca2+ homeostasis imbalance and myocardial hypertrophy in SLC25A3-related hypertrophic cardiomyopathy60
Molecular, metabolic, and functional CD4 T cell paralysis in the lymph node impedes tumor control60
Loss of the proton-activated chloride channel in neurons impairs AMPA receptor endocytosis and LTD via endosomal hyper-acidification60
Active APPL1 sequestration by Plasmodium favors liver-stage development60
Differential DNA damage repair and PARP inhibitor vulnerability of the mammary epithelial lineages60
SARS-CoV-2 3CLpro (main protease) regulates caspase activation of gasdermin-D/E pores leading to secretion and extracellular activity of 3CLpro60
Bioengineering for robust tolerance against cold and drought stresses via co-overexpressing three Cu-miRNAs in major food crops60
Serum- and glucocorticoid-induced kinase drives hepatic insulin resistance by directly inhibiting AMP-activated protein kinase59
Dietary restriction induces a sexually dimorphic type I interferon response in mice with gene-environment interactions59
Bodies in motion: Unraveling the distinct roles of motion and shape in dynamic body responses in the temporal cortex59
p120 RasGAP and ZO-2 are essential for Hippo signaling and tumor-suppressor function mediated by p190A RhoGAP59
A neural circuit integrates pharyngeal sensation to control feeding59
Stromal cell and B cell dialogue potentiates IL-33-enriched lymphoid niches to support eosinophil recruitment and function during type 2 immunity59
T-bet deficiency and Hic1 induction override TGF-β-dependency in the formation of CD103+ intestine-resident memory CD8+ T cells59
CYLD deubiquitinates plakoglobin to promote Cx43 membrane targeting and gap junction assembly in the heart59
Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA ubiquitination59
The cellular basis of mechanosensation in mammalian tongue59
A tug of war between DCC and ROBO1 signaling during commissural axon guidance59
Documenting the diversity of the Namibian Ju|’hoansi intestinal microbiome58
T-type Ca2+ and persistent Na+ currents synergistically elevate ventral, not dorsal, entorhinal cortical stellate cell excitability58
ERK activation dynamics in maturing oocyte controls embryonic nuclear divisions in Caenorhabditis elegans58
Autocleavage of separase suppresses its premature activation by promoting binding to cyclin B158
Redefining sensorimotor mismatch selectivity in the visual cortex58
CRISPR screening identifies PRMT1 as a key pro-ferroptotic gene via a two-layer regulatory mechanism58
Hippocampal and medial prefrontal ensemble spiking represents episodes and rules in similar task spaces58
Human antibodies in Mexico and Brazil neutralizing tick-borne flaviviruses58
A ribosome-bound tRNA half stimulates mitochondrial translation during stress recovery in Trypanosoma brucei58
Pak2-mediated phosphorylation promotes RORγt ubiquitination and inhibits colonic inflammation58
Cd99l2 regulates excitatory synapse development and restrains immediate-early gene activation57
Bordetella spp. block eosinophil recruitment to suppress the generation of early mucosal protection57
C9ORF72 poly-PR induces TDP-43 nuclear condensation via NEAT1 and is modulated by HSP70 activity57
Newly synthesized AIFM1 determines the hypersensitivity of T lymphocytes to STING activation-induced cell apoptosis57
miRNA-mediated inhibition of an actomyosin network in hippocampal pyramidal neurons restricts sociability in adult male mice57
Crimean-Congo hemorrhagic fever survivors elicit protective non-neutralizing antibodies that target 11 overlapping regions on glycoprotein GP3856
Landscape and regulation of mRNA translation in the early C. elegans embryo56
Probing the functional constraints of influenza A virus NEP by deep mutational scanning56
Critical contribution of 3′ non-seed base pairing to the in vivo function of the evolutionarily conserved let-7a microRNA56
ERK1/2 interaction with DHPS regulates eIF5A deoxyhypusination independently of ERK kinase activity56
Targeting WEE1 in tumor-associated dendritic cells potentiates antitumor immunity via the cGAS/STING pathway56
SETDB1 promotes mammalian liver regeneration by stimulating cytokine CSF3 in hepatocytes56
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