OOIR: Observatory of International Research

Papers

(The H4-Index of Molecular Cancer is 90. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Crosstalk between cancer-associated fibroblasts and immune cells in the tumor microenvironment: new findings and future perspectives	692
Circular RNA: metabolism, functions and interactions with proteins	522
The potential role of RNA N6-methyladenosine in Cancer progression	496
mRNA vaccine for cancer immunotherapy	443
Targeting STAT3 in Cancer Immunotherapy	416
Combination strategies with PD-1/PD-L1 blockade: current advances and future directions	398
The cancer metabolic reprogramming and immune response	380
Ferroptosis in cancer therapy: a novel approach to reversing drug resistance	356
Regulatory T cells in tumor microenvironment: new mechanisms, potential therapeutic strategies and future prospects	353
Natural killer cells in cancer biology and therapy	331
The role of long noncoding RNAs in hepatocellular carcinoma	293
Cancer cell-derived exosomal circUHRF1 induces natural killer cell exhaustion and may cause resistance to anti-PD1 therapy in hepatocellular carcinoma	279
RETRACTED ARTICLE: LncRNA BCRT1 promotes breast cancer progression by targeting miR-1303/PTBP3 axis	277
Glioma targeted therapy: insight into future of molecular approaches	275
Exosomes as a new frontier of cancer liquid biopsy	249
Exosomal circPACRGL promotes progression of colorectal cancer via the miR-142-3p/miR-506-3p- TGF-β1 axis	248
Epigenetic regulation in human cancer: the potential role of epi-drug in cancer therapy	246
The circRNA circSEPT9 mediated by E2F1 and EIF4A3 facilitates the carcinogenesis and development of triple-negative breast cancer	242
The role of m6A, m5C and Ψ RNA modifications in cancer: Novel therapeutic opportunities	240
Exosome-based immunotherapy: a promising approach for cancer treatment	239
G-quadruplexes: a promising target for cancer therapy	238
Targeting AURKA in Cancer: molecular mechanisms and opportunities for Cancer therapy	237
Exosomal circSHKBP1 promotes gastric cancer progression via regulating the miR-582-3p/HUR/VEGF axis and suppressing HSP90 degradation	235
m6A-dependent glycolysis enhances colorectal cancer progression	234
Targeting TGF-β signal transduction for fibrosis and cancer therapy	231

PARP inhibitor resistance: the underlying mechanisms and clinical implications	228
Liquid biopsy: a step closer to transform diagnosis, prognosis and future of cancer treatments	226
LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes	224
RNA demethylase ALKBH5 prevents pancreatic cancer progression by posttranscriptional activation of PER1 in an m6A-YTHDF2-dependent manner	221
Wnt signaling in breast cancer: biological mechanisms, challenges and opportunities	213
Wnt signaling in colorectal cancer: pathogenic role and therapeutic target	213
The role of m6A RNA methylation in cancer metabolism	196
CircRNA inhibits DNA damage repair by interacting with host gene	194
The role of ubiquitination and deubiquitination in cancer metabolism	191
Taking the Myc out of cancer: toward therapeutic strategies to directly inhibit c-Myc	186
mRNA vaccine: a potential therapeutic strategy	182
METTL14-mediated N6-methyladenosine modification of SOX4 mRNA inhibits tumor metastasis in colorectal cancer	179
Long non-coding RNAs towards precision medicine in gastric cancer: early diagnosis, treatment, and drug resistance	178
Circular RNAs in body fluids as cancer biomarkers: the new frontier of liquid biopsies	172
Mechanisms of vasculogenic mimicry in hypoxic tumor microenvironments	172
The role of N6-methyladenosine (m6A) modification in the regulation of circRNAs	170
Mechanism of RNA modification N6-methyladenosine in human cancer	168
Circular RNA circSATB2 promotes progression of non-small cell lung cancer cells	168
mRNA therapeutics in cancer immunotherapy	164
Long non-coding RNA NEAT1 promotes bone metastasis of prostate cancer through N6-methyladenosine	164
N6-methyladenosine-modified CircRNA-SORE sustains sorafenib resistance in hepatocellular carcinoma by regulating β-catenin signaling	163
Interaction between N6-methyladenosine (m6A) modification and noncoding RNAs in cancer	159
ALKBH5 suppresses malignancy of hepatocellular carcinoma via m6A-guided epigenetic inhibition of LYPD1	158
Long noncoding RNAs: functions and mechanisms in colon cancer	155
N6-methyladenosine-modified circIGF2BP3 inhibits CD8+ T-cell responses to facilitate tumor immune evasion by promoting the deubiquitination of PD-L1 in non-small cell lung cancer	147
YTHDF2 mediates the mRNA degradation of the tumor suppressors to induce AKT phosphorylation in N6-methyladenosine-dependent way in prostate cancer	146
Novel insights into the interplay between m6A modification and noncoding RNAs in cancer	143
m6A modification: recent advances, anticancer targeted drug discovery and beyond	138
Overcoming immunotherapy resistance in non-small cell lung cancer (NSCLC) - novel approaches and future outlook	136
Engineered exosomes as an in situ DC-primed vaccine to boost antitumor immunity in breast cancer	135
A novel protein encoded by circFNDC3B inhibits tumor progression and EMT through regulating Snail in colon cancer	134
Upregulation of METTL14 mediates the elevation of PERP mRNA N6 adenosine methylation promoting the growth and metastasis of pancreatic cancer	134
Circular RNA circMET drives immunosuppression and anti-PD1 therapy resistance in hepatocellular carcinoma via the miR-30-5p/snail/DPP4 axis	132
Cross-talk of four types of RNA modification writers defines tumor microenvironment and pharmacogenomic landscape in colorectal cancer	132
circCUL2 regulates gastric cancer malignant transformation and cisplatin resistance by modulating autophagy activation via miR-142-3p/ROCK2	128
Novel insight into the regulatory roles of diverse RNA modifications: Re-defining the bridge between transcription and translation	127
METTL3/IGF2BP3 axis inhibits tumor immune surveillance by upregulating N6-methyladenosine modification of PD-L1 mRNA in breast cancer	127
Comprehensive landscape of extracellular vesicle-derived RNAs in cancer initiation, progression, metastasis and cancer immunology	126
cGAS-STING pathway in cancer biotherapy	121
Cancer associated-fibroblast-derived exosomes in cancer progression	120
Circular RNA circCCDC9 acts as a miR-6792-3p sponge to suppress the progression of gastric cancer through regulating CAV1 expression	119
A novel protein encoded by circMAPK1 inhibits progression of gastric cancer by suppressing activation of MAPK signaling	118
EWSR1-induced circNEIL3 promotes glioma progression and exosome-mediated macrophage immunosuppressive polarization via stabilizing IGF2BP3	117
The circular RNA circ-ERBIN promotes growth and metastasis of colorectal cancer by miR-125a-5p and miR-138-5p/4EBP-1 mediated cap-independent HIF-1α translation	117
Role of oncogenic KRAS in the prognosis, diagnosis and treatment of colorectal cancer	116
Liquid biopsy in lung cancer: significance in diagnostics, prediction, and treatment monitoring	115
Exosome biogenesis: machinery, regulation, and therapeutic implications in cancer	114
Comprehensive elaboration of the cGAS-STING signaling axis in cancer development and immunotherapy	114
Cuproptosis: mechanisms and links with cancers	113
Circular RNA CDR1as disrupts the p53/MDM2 complex to inhibit Gliomagenesis	111

Lung cancer immunotherapy: progress, pitfalls, and promises	110
Epigenetic modulation of antitumor immunity for improved cancer immunotherapy	105
CircECE1 activates energy metabolism in osteosarcoma by stabilizing c-Myc	104
Circular RNA hsa_circ_0004872 inhibits gastric cancer progression via the miR-224/Smad4/ADAR1 successive regulatory circuit	103
circNFIB1 inhibits lymphangiogenesis and lymphatic metastasis via the miR-486-5p/PIK3R1/VEGF-C axis in pancreatic cancer	103
Expression profiles, biological functions and clinical significance of circRNAs in bladder cancer	99
Progress on pivotal role and application of exosome in lung cancer carcinogenesis, diagnosis, therapy and prognosis	98
RETRACTED ARTICLE: CircTLK1 promotes the proliferation and metastasis of renal cell carcinoma by sponging miR-136-5p	98
Circ3823 contributes to growth, metastasis and angiogenesis of colorectal cancer: involvement of miR-30c-5p/TCF7 axis	96
LncRNA CRNDE attenuates chemoresistance in gastric cancer via SRSF6-regulated alternative splicing of PICALM	94
Cancer cell-derived exosomal circUSP7 induces CD8+ T cell dysfunction and anti-PD1 resistance by regulating the miR-934/SHP2 axis in NSCLC	93
DDX3X: structure, physiologic functions and cancer	93
Circular RNA circ_0020710 drives tumor progression and immune evasion by regulating the miR-370-3p/CXCL12 axis in melanoma	93
Engineering the next-generation of CAR T-cells with CRISPR-Cas9 gene editing	91
Circular HER2 RNA positive triple negative breast cancer is sensitive to Pertuzumab	91
Identification of tumor antigens and immune subtypes of pancreatic adenocarcinoma for mRNA vaccine development	90