OOIR: Observatory of International Research

Papers

(The TQCC of Physiological Genomics is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Prolonged obesity alters males’ adipose profile: implications for disease?	30
Investigative power of genomic informational field theory relative to genome-wide association studies for genotype-phenotype mapping	28
Identification of shared and disease-specific intratumoral microbiome-host gene associations in gastrointestinal tumors	23
Analysis of a genetic region affecting mouse body weight	23
Impact of stress phenotype, elevated temperature, and bacterin exposure on male Atlantic salmon (Salmo salar) growth, stress, and immune biomarker gene expression	20
Kidney cell type-specific changes in the chromatin and transcriptome landscapes following epithelial Hdac1 and Hdac2 knockdown	19
Lysine demethylase KDM6B regulates HIF-1α-mediated systemic and cellular responses to intermittent hypoxia	18
Assessing the impact of boldine on the gastrocnemius using multiomics profiling at 7 and 28 days post-complete spinal cord injury in young male mice	18
A long-term high-fat diet induces differential gene expression changes in spatially distinct adipose tissue of male mice	17
Maternal and fetal mitochondrial gene dysregulation in hypertensive disorders of pregnancy	16
Dose-dependent progression of multiple low-dose streptozotocin-induced diabetes in mice	16
The expression profile of 79 genes from 107 viruses revealed new insights into disease susceptibility in rats, mice, and muskrats	15
Transcriptomic responses of equine skeletal muscle to acute exercise in a hot environment	14
Mapping cardiac electrical abnormalities in rodents	14
Genetic background determines renal response to chronic lithium treatment in female mice	14
Deciphering taxonomic and functional patterns of microbial communities associated with the tiger tail seahorse (Hippocampus comes)	14
Changes in environmental stress over COVID-19 pandemic likely contributed to failure to replicate adiposity phenotype associated with Krtcap3	13
Systems genetics analysis defines importance of TMEM43/LUMA for cardiac- and metabolic-related pathways	12
Global phosphoproteomic profiling of skeletal muscle in ovarian hormone-deficient mice	12
Cardiac biomarker responses following high-intensity interval and continuous exercise: the influence of ACE-I/D gene polymorphism and training status in men	12
Integrated analysis of transcriptome profiling of lncRNAs and mRNAs in livers of type 2 diabetes mellitus	12
Knockout of Hsp70 genes significantly affects locomotion speed and gene expression in leg skeletal muscles of Drosophila melanogaster	11
Gene expression profile and injury sites in mice treated with Shiga toxin 2 and lipopolysaccharide as a Shiga toxin-associated hemolytic uremic syndrome model	11
Physiological, biochemical, and genome-wide expression patterns during graded normobaric hypoxia in healthy individuals	11
MicroRNA-499-5p promotes vascular smooth muscle cell proliferation and migration via inhibiting SOX6	11

Platelet proteome dynamics in hibernating 13-lined ground squirrels	10
Fecal dysbiosis and inflammation in intestinal-specific Cftr knockout mice on regimens preventing intestinal obstruction	10
Single-cell profiling of the peripheral blood immune landscape during mid- and late-stage pregnancy	9
Kidney cell response to acute cardiorenal and isolated kidney ischemia-reperfusion injury	9
Gut microbiome and host interactions in catfish: hybridization structures bacterial communities along catfish intestinal tract	9
Transcriptomics and proteomics revealed sex differences in human pulmonary microvascular endothelial cells	9
RNA sequencing indicates age-dependent shifts in the cardiac fibroblast transcriptome between fetal, neonatal, and adult developmental ages	9
Host-microbiota interactions contributing to the heterogeneous tumor microenvironment in colorectal cancer	8
Off the shelf: Regulation of fish blood pH through ionocyte membrane remodelling and protein translocation without additional synthesis	8
Associations between circulating microRNAs and coronary plaque characteristics: potential impact from physical exercise	8
Gut microbiota of wild fish as reporters of compromised aquatic environments sleuthed through machine learning	8
Metabolomic pattern associated with physical sequelae in patients presenting with respiratory symptoms validates the aestivation concept in dehydrated patients	7
Retraction for Huang et al., PEA15-HKII, stabilized by U2AF2, form a molecular switch governing cellular fate after spinal cord injury via MAPK pathway	7
The genetic regulation of the gastric transcriptome is associated with metabolic and obesity-related traits and diseases	7
Alternative splicing of CADM1 is associated with endothelial progenitor cell dysfunction in preeclampsia	7
Lost in translation? Evidence for a muted proteomic response to thermal stress in a stenothermal Antarctic fish and possible evolutionary mechanisms	7
Lung proinflammatory microRNA and cytokine expression in a mouse model of allergic inflammation: role of sex chromosome complement and gonadal hormones	7
Gut microbial composition and diversity varies by CREBRF genotype among Samoan infants	6
Low carbohydrate availability promotes a distinct circulating microRNA profile 24 h following aerobic exercise	6
Sex and molecular differences in cardiovascular parameters at peak influenza disease in mice	6
Vacuole membrane protein 1 and miRNA-21: are they reliable partners to rescue acute kidney injury?	6
Maternal-fetal interfaces transcriptome changes associated with placental insufficiency and a novel gene therapy intervention	6
Blood pressure and the kidney cortex transcriptome response to high-sodium diet challenge in female nonhuman primates	6
Immune and metabolic challenges induce changes in pain sensation and related pathways in the hypothalamus	6
Differences in the bacterial communities along the intestinal tract of juvenile channel (Ictalurus punctatus) and hybrid (I. punctatus× I. furcatus) catfish	6
Podocyte cell-specific Npr1 is required for blood pressure and renal homeostasis in male and female mice: role of sex-specific differences	6
Epigenetic fluctuations underlie gene expression timescales and variability	6
Extracellular vesicle-mediated transfer of lncRNA CLDN10-AS1 aggravates low-density lipoprotein-induced vascular endothelial injury	6
The skeletal muscle of aged male mice exhibits sustained growth regulatory transcriptional profile following glucocorticoid exposure compared to young males	5
A genetic variant associated with aquaporin 3 expression is correlated to in-hospital death in COVID-19 patients with extracellular hyperosmolality	5
Resistance exercise differentially alters extracellular vesicle size and subpopulation characteristics in healthy men and women: an observational cohort study	5
Myocardial transcriptomic and proteomic landscapes across the menopausal continuum in a murine model of chemically induced accelerated ovarian failure	5
Drivers of transcriptional variance in human intestinal epithelial organoids	5
DNA methylation dynamics in the small intestine of egg-selected laying hens along egg production stages	5
Computational modeling of the synergistic role of GCN2 and the HPA axis in regulating the integrated stress response in the central circadian timing system	5
Knockdown of deoxythymidylate kinase suppresses progression and epithelial-mesenchymal-transition of lung adenocarcinoma via STAT3 signaling	5