OOIR: Observatory of International Research

Papers

(The TQCC of Panminerva Medica is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
The effects of nutritional support on cellular immunity of the patient with multiple myeloma undergoing chemotherapy	39
Analysis of prenatal value of ultrasonography in diagnosis of fetal malformation in early pregnancy	32
Study on the cleaning effect of heavily polluted instrument cleaners on energy instruments in the manual brush-free cleaning process	28
Efficacy of hypofractionated radiotherapy combined with docetaxel in middle and advanced non-small cell lung cancer and its effects on serum MMP-9 and VEGF expressions	27
Thymosin α1 alleviates lung injury in sepsis rats via Notch signaling pathway	26
Left atrial appendage closure: a new strategy for cardioembolic events despite oral anticoagulation	24
An update on the pathophysiology of acute and recurrent pericarditis	23
The effect and mechanism of CDK11 in promoting breast cancer cell proliferation, migration, and doxorubicin resistance by regulating EGFR	23
The operation of carotid endarterectomy: is it an effective method of treatment of arterial hypertension?	21
Comparative study of efficacy of breast-conserving surgery and modified radical mastectomy in treating early breast cancer	21
Metabolically healthy obesity and chronic kidney disease risk: exploring the dynamics	20
MiR-379 relieves myocardial injury after acute myocardial infarction by regulating tumor necrosis factor-α-induced protein 8	19
The intergated approach to the management of arterial hypertension: The Campania Salute Network	18
Can selective serotonin reuptake inhibitors/serotonin and norepinephrine reuptake inhibitor antidepressants decrease the "cytokine storm" in the course of COVID-19 pneumonia?	18
Exploration on the recovery of lung function by fast track surgery in patients with radical resection of lung cancer	17
MiR-21 accelerates tibial fracture healing in rats by regulating TGF-β1/Smad signaling pathway	16
Analysis of the clinical effect of posterior focus debridement and interbody bone grafting in the treatment of spinal tuberculosis	16
Helicobacter pylori eradication in elderly patients: can we assume that a bismuth-based therapy is effective as in young people?	15
Effect of high-quality nursing intervention in obstetrics and gynecology nursing	15
Ethical issues surrounding appropriate care for older persons in the Intensive Care Unit	15
Application effect of humanized nursing in the treatment of ovarian cancer with paclitaxel and cisplatin	14
The art of ART: an editorial	14
Chronic venous insufficiency and microangiopathy: supplementation with Pycnogenol® reduces the progression of venous disease in women	14
Newer therapeutic approaches towards the management of diabetes mellitus: an update	14
Correlations of inflammation, oxidative stress and prognosis with expression of lncRNA H19 in rats with sepsis-evoked lung injury	13

Microbiota treatment: the future target to prevent cardiovascular disease?	13
Correlation between blood glucose changes and sleep quality in type 2 diabetes patients with sleep disorders	12
Poorly differentiated thyroid carcinoma: molecular, clinico-pathological hallmarks and therapeutic perspectives	12
Pharmacologic treatment of acute and recurrent pericarditis: a systematic review and meta-analysis of controlled clinical trials	11
The evaluation of meticulous and humanized nursing management mode on patient's physiology, psychology and comfort level as well as the incidence of adverse events in operating room	11
The URRAH study	11
The vaccine journey for COVID-19: a comprehensive systematic review of current clinical trials in humans	11
Analysis of incidence and influencing factors of hyperuricemia in elderly patients with hypertension	11
Application value of Doppler ultrasound in renal hemodynamic monitoring in patients with septic shock	10
Study on the cleaning effect of medical protective positive pressure air supply respirator during COVID-19	10
Effect of simvastatin on fracture healing of type 2 diabetic rats	10
LncRNA CASC7 inhibits myocardial apoptosis in myocardial ischemia-reperfusion rats by regulating MiR-21 expression	9
Microbiota restoration for recurrent Clostridioides difficile infection	9
Corrected and republished from: Metabolic associated liver disease	9
Perspectives on the profiling of renal risk in obesity	9
Study of febuxoat and allopurinol placebo in patients with high uric acid excretion and calcium stones	9
Correlation of MRI findings, pathological differentiation with GPC3, CD34, CK19, CK7 expression and prognosis in patients with hepatocellular carcinomas	9
One-year of pulmonologist-based teleconsultation between hospital and general practitioners: an Italian exploratory investigation	8
The PAMELA research project: a 25-year long journey	8
Impact of anabolic androgenic steroids on male sexual and reproductive function: a systematic review	8
Thymic stromal lymphopoietin alleviates fibrosis after myocardial infarction through regulating STAT3	8
The effect and exploration of continuous positive pressure ventilation combined with upper limb robot training on upper limb function in stroke patients with OSAHS	8
Implantation of one, two or multiple MitraClip™ for transcatheter mitral valve repair: insights from a 1824-patient multicenter study	8
A report on the Gubbio Study thirty-eight years after its inception	8
Vitamin D and non-Hodgkin lymphomas, trends from an Italian monocentric study	7
Effect of baicalin combined with adipose stem cells on promoting angiogenesis and improving wound healing in diabetes	7
A nutrigenetic tool for precision dietary management of non-alcoholic fatty liver disease deeming insulin resistance markers	7
Long non-coding RNA MALAT1 promotes cell proliferation, migration and invasion in cervical cancer by targeting miR-625-5p and AKT2	7
Clinical effect of urinary kallindinogenase in the treatment of acute cerebral infarction of different TOAST types	7
LncRNA CYTOR and MIR4435-2HG in ovarian cancer and its relationship with clinicopathological features	7
Preoperative management of medications for psychiatric disorders	7
Effect and mechanism of mir-574-5p regulating mpegs on drug resistance of pC9/h1993 cells	7
Prevalence of airflow obstruction in an apparently healthy population sample: a preliminary Italian study	7
MiR-29c-3p inhibits proliferation and migration in rat primary cardiac fibroblasts via interacting with STAT3	7
Clinical study of early intervention of brain-derived nerve growth factor on reducing the degree of brain injury in newborns with severe asphyxia	7
Analysis of changes in cardiac function parameters before and after surgery in OSAS patients	6
MiR-30d inhibits cardiomyocytes autophagy promoting ferroptosis after myocardial infarction	6
Application of comprehensive nursing intervention in nursing of patients with bronchial asthma and allergic rhinitis	6
Difficulty encountered in the early radiological diagnosis of atypical pancreatic duct stones compared to the typical type in Chinese patients	6
A recombinant adenovirus fiber knob protein sensitizes gastric cancer cells to trastuzumab	6
Effect of interferon-α-2b and interleukin-2 combined with chemotherapy in metastatic melanoma	6
Arthroscopic treatment for popliteal cysts	6
Acute leukemia diagnosis during the COVID-19 pandemic	6
Clinical efficacy analysis of rehabilitation therapy for patients with neurological dysfunction caused by cerebrovascular disease	6
Effect observation and satisfaction analysis of rehabilitation nursing intervention in rheumatoid arthritis nursing	6
Rosuvastatin reduces expression of tissue factor through inhibiting RhoA/ROCK pathway to ameliorate atherosclerosis	6
Exploring the relationship between the oral microbiota and fasting blood glucose level based on the analysis of NHANES data	6
Correlation analysis between ADRB1 gene polymorphism and eclampsia	6
Moving towards core antigen for the management of patients with overt and occult HBV infection	6
The value of oral contrast-enhanced ultrasonography in the diagnosis of gastric tumors in the elderly	5

Effect of N6 adenylate methylation on myocardial hypertrophy through METTL14 regulation	5
Meta-analysis of women's reproductive tract infection survey	5
Keep on tailoring CMV management in lung transplantation: 24 versus 12-month CMV hyperimmune globulins regimen effects in combined universal prophylaxis	5
Clinical features and risk factors in patients with acute myocardial infarction in different age groups	5
Novel insights on lymphoma and lymphomagenesis in primary Sjögren's Syndrome	5
Effect of cognitive dysfunction on the outcome of coronary artery bypass grafting in patients	5
The Vobarno Study	5
Effect analysis of recombinant human growth hormone therapy in short stature children	5
Observation on the effect of modified adhesive retained posterior implant denture on the tissue around the implant	5
MiR-21-5p reduces apoptosis and inflammation in rats with spinal cord injury through PI3K/AKT pathway	5
miR-30c inhibited cell migration and invasion via LGI1 in clear cell renal cell carcinoma	5
Alcohol dehydrogenase 2/aldehyde dehydrogenase 2 genetic polymorphisms in obstructive sleep apnea syndrome	5
LncRNA PVT1 participates in the development of oral squamous cell carcinomas through accelerating EMT and serves as a diagnostic biomarker	5
miR-495 inhibits fibroblast-like synoviocyte proliferation and inflammation in rheumatoid arthritis rats via Wnt signaling pathway	4
CA-074Me inhibits cathepsin-B and alleviates fibrosis after myocardial infarction	4
Correlation of MMP-2 gene polymorphism with neonatal hypoxic-ischemic encephalopathy	4
Effect of repetitive transcranial magnetic stimulation on quality of life and cortical excitability in patients with cerebral infarction	4
Experience summary of a COVID-19 designated community hospital and its operation model	4
Metabolic syndrome and andrological diseases	4
Effects of edaravone on cerebral ischemia-reperfusion in mice through the TLR4/NF-κB/TNF-α pathway	4
Effectiveness of tocilizumab in hospitalized moderate-to-severe COVID-19 patients: a real-life study	4
Protein kinase TBK1/IKKε inhibitor Amlexanox improves cardiac function after acute myocardial infarction in rats	4
Acquired hemophilia A induced by clopidogrel	4
Protective effect of anthocyanin B2 on traumatic optic nerve injury in rats	4
Therapeutic effects of 595-nm pulsed dye laser on children's nevus flammeus and incidence of adverse reactions	4
Analysis of the predictive value of real-time shear wave elastography in detecting the elastic hardness of liver and spleen in patients with portal hypertension of hepatitis B cirrhosis	4
Wernicke encephalopathy, myasthenia gravis, or both?	4
The Progetto Ipertensione Umbria Monitoraggio Ambulatoriale (PIUMA) Study	4
Efficacy and safety of long-term warfarin anticoagulation in elderly non-valvular atrial fibrillation patients	4
Efficacy analysis of continuous blood purification therapy for patients with severe acute pancreatitis and acute kidney injury	4
LncRNA CCAT2 promotes the proliferation and invasion of renal cell cancer by sponging miR-320a	4
MiR-181a reduces radiosensitivity of non-small-cell lung cancer via inhibiting PTEN	4
Recurrent pericarditis: an update on diagnosis and management	4
Study on the efficacy and safety of fallopian tube interventional recanalization in the treatment of tubal obstructive infertility	4
ICSI for non-male factor infertility: time to reappraise IVF?	4
LncRNA GHET1 promotes osteoblast proliferation and differentiation by inhibiting PTEN	4
Analysis of diagnostic efficacy and curative effect assessment value of computed tomography and magnetic resonance imaging for atherosclerosis	4
Rapid calcification after large area cerebral infarction	4
Pranoprofen inhibits endoplasmic reticulum stress-mediated apoptosis of chondrocytes	4
lncRNA-Gm4419 alleviates renal damage in rats with diabetic nephropathy through NF-κB pathway	3
tudy on the effect of heart-shaped tension-reducing cosmetic suture on reducing the formation of abdominal scar in cesarean section	3
Noninvasive biomarkers in predicting nonalcoholic steatohepatitis and assessing liver fibrosis: systematic review and meta-analysis	3
Metabolic syndrome and prostate cancer treatment	3
Sarcopenia increases mortality risk in liver transplantation: a systematic review and meta-analysis	3
Primary benign back pain: supplementation with Pycnogenol®	3
Sperm DNA fragmentation test: usefulness in assessing male fertility and assisted reproductive technology outcomes	3
Clinical decisions for appropriate management of patients with atrial fibrillation	3
Effect of transurethral resection of prostate combined with endocrine castration therapy in the treatment of advanced prostate cancer patients with urinary retention	3
Thromboembolism in COVID-19: the unsolved problem	3
Restless legs syndrome: prevention with Pycnogenol® and improvement of the venoarteriolar response	3
Parecoxib protects against myocardial ischemia/reperfusion via targeting PKA-CREB signaling pathway	3
Long non-coding RNA LINC00299 knockdown inhibits ox-LDL-induced T/G HA-VSMC injury by regulating miR-135a-5p/XBP1 axis in atherosclerosis	3
Complete versus culprit-only coronary revascularization in patients with myocardial infarction and multivessel disease undergoing percutaneous coronary intervention: an updated meta-analysis	3
ChatGPT: unlocking the potential of Artifical Intelligence in COVID-19 monitoring and prediction	3
Comparative observation on the effect of laparoscopic sleeve gastrectomy and routine weight loss in the treatment of obesity and the improvement of blood pressure	3
Oocyte quality and embryo selection strategies: a review for the embryologists, by the embryologists	3
Study on the effect of high-quality nursing intervention mode on the improvement of emotional status of breast cancer patients	3
Tracheo-esophageal fistula repair in a positive COVID-19 patient: use of intercostal muscle flap	3
Study on the effect of continuous nursing intervention model on promoting maternal and infant health after delivery	3
The expression of Nrf2-ARE signaling pathway combined with plasma platelet activating factor in elderly patients with respiratory failure and its correlation with lung function	3
Mantle cell lymphoma: from pathogenesis to treatment for 2024 and beyond	3
The expression of CT quantitative indicators in patients with chronic obstructive pulmonary disease and their correlation with lung function	3
Application effect of foreseeable nursing concept on patients postoperative acute pressure injury after spinal posterior approach surgery	3
The HARVEST: looking for optimal management of young people with stage 1 hypertension	3
HMGA1 promotes the development of esophageal squamous cell carcinoma by mediating miR-671-5p/lncRNA DLEU1	3
Diet as a possible influencing factor in thyroid cancer incidence: the point of view of the nutritionist	3
Tricuspid regurgitation: a contemporary review	3
MiR-132 represses sepsis-induced myocardial injury in rats by regulating SIRT1 expression	3
Thirty years of ICSI: quality assessment and selection of gametes and embryos. Where are we in 2023?	3
Efficacy observation and analysis of metoprolol combined with dopamine in patients with severe pneumonia complicated with heart failure	3
lncRNA SNHG16 in myocardial cell injury induced by acute myocardial infarction and the underlying functional regulation mechanism	3
Observation of effect of pulse debridement combined with prp in the healing of chronic ulcers of lower limbs	3
Impact of the first COVID-19 lockdown in Austria on laboratory and mental parameters in diabetic patients: a retrospective analysis highlighting the importance of regular medical consultations in a pa	3
Dizziness, psychological disorders and cognitive decline	3
The effect of frailty on in-hospital and medium-term mortality of patients with COronaVIrus Disease-19: the FRACOVID study	3
Analysis of the effect of multimedia-assisted psychological nursing in perioperative period of cardiac surgery with cardiopulmonary bypass	3
Efficacy of the combination Pycnogenol® and Centellicum® on preventing the progression of atherosclerotic plaques: a morphological study	3
An expert commentary on essential equipment, supplies and culture media in the assisted reproductive technology laboratory	3
Long-term physical activity modulates adipsin and ANGPTL4 serum levels, a potential link to exercise-induced metabolic changes	3
Diosgenin inhibits the proliferation and migration of MCF-7 breast cancer cells through the demethylation of miR-145 gene	3