Journal of Cell Science

Article	Citations
Functional residuomics – analyzing how missense mutations impact cellular systems	95
First person – Francisca Vitorino	89
PI31 is a positive regulator of 20S immunoproteasome assembly	78
Approaches to reduce succinate accumulation by restoration of succinate dehydrogenase activity in cultured adrenal cells	73
Reprogramming macrophages with R848-loaded artificial protocells to modulate skin and skeletal wound healing	69
First person – Neža Vadnjal	66
First person – Syed Qaaifah Gillani	66
The roles of dynein and myosin VI motor proteins in endocytosis	65
Estimation of microtubule-generated forces using a DNA origami nanospring	63
Interview with FocalPlane Scientific Advisory Board member Jennifer Waters	56
First person – Aude Pascal	55
First person – Celia Segui-Perez	54
Interview with the Guest Editor – James Olzmann	54
First person – Akruti Shah	53
The worst	52
Mitochondrial antiviral-signalling protein is a client of the BAG6 protein quality control complex	50
The system III – the workplace	48
First person – Abhishek Shinde	46
Apolipoprotein A1 deficiency in mice primes bone marrow stem cells for T cell lymphopoiesis	46
Live-imaging studies reveal how microclots and the associated inflammatory response enhance cancer cell extravasation	44
Let's review I	43
TC10 on endosomes regulates the local balance between microtubule stability and dynamics through the PAK2-JNK pathway and promotes axon outgrowth	41
PCTAIRE1 promotes mitotic progression and resistance against antimitotic and apoptotic signals	40
α- and β-tubulin C-terminal tails with distinct modifications are crucial for ciliary motility and assembly	39
Polo-like kinase 1 regulates immune synapse assembly and cytotoxic T cell function by driving microtubule dynamics	39

First person – Olivera Mitevska	39
Altered cohesin dynamics and H3K9 modifications contribute to mitotic defects in thecbf11Δlipid metabolism mutant	38
First person – François Tyckaert	37
First person – M. H. D. Fouad Zakaria	36
The dual Ras-association domains of Drosophila Canoe have differential roles in linking cell junctions to the cytoskeleton during morphogenesis	35
Near-infrared imaging in fission yeast using a genetically encoded phycocyanobilin biosynthesis system	34
LCN2 promotes focal adhesion formation and invasion by stimulating c-Src activation	34
Expression of Concern: RyR1 and RyR3 isoforms provide distinct intracellular Ca2+ signals in HEK 293 cells	33
Correction: Actin remodeling requires ERM function to facilitate AQP2 apical targeting	33
Spatiotemporal regulation of organelle transport by spindle position checkpoint kinase Kin4	32
Confinement plus myosin-II suppression maximizes heritable loss of chromosomes, as revealed by live-cell ChReporters	32
First person – Gianna Fote	32
First person – Alice Dupont Juhl	32
Metformin inactivates the cGAS-STING pathway through autophagy and suppresses senescence in nucleus pulposus cells	32
Glucocorticoids enhance chemotherapy-driven stress granule assembly and impair granule dynamics, leading to cell death	31
Interview with Journal of Cell Science Editor Rob Parton	31
The AHR target gene scinderin activates the WNT pathway by facilitating the nuclear translocation of β-catenin	30
UMAD1 contributes to ESCRT-III dynamic subunit turnover during cytokinetic abscission	30
The insect perspective on Z-disc structure and biology	30
First person – Carolina Camelo	29
Cell volume regulates terminal differentiation of cultured human epidermal keratinocytes	29
The role of mitochondrial mRNA translation in cellular communication	29
SUN4 is a spermatid type II inner nuclear membrane protein that forms heteromeric assemblies with SUN3 and interacts with lamin B3	28
Microtubules under mechanical pressure can breach dense actin networks	27
Culture substrate stiffness impacts human myoblast contractility-dependent proliferation and nuclear envelope wrinkling	27
Augmin complex activity finetunes dendrite morphology through non-centrosomal microtubule nucleation in vivo	27
Cell cycle-dependent palmitoylation of protocadherin 7 by ZDHHC5 promotes successful cytokinesis	27
Preferential recruitment and stabilization of Myosin II at compartment boundaries in Drosophila	26
First person – Aaron Fountain and Mélanie Mansat	26
ER–mitochondria encounter structure connections determine drug sensitivity and virulence of Cryptococcus neoformans	26
Cellular effects of NAT-mediated histone N-terminal acetylation	26
Three-dimensional beating pattern of ciliary tip in the live ciliate Tetrahymena	26
MITOL-mediated DRP1 ubiquitylation and degradation promotes mitochondrial hyperfusion in a CMT2A-linked MFN2 mutant	26
Beyond cysts: Organization of epithelial networks in the murine thymus	26
Affimers and nanobodies as molecular probes and their applications in imaging	25
Nuclear speckles – a driving force in gene expression	25
ARF6 plays a general role in targeting palmitoylated proteins from the Golgi to the plasma membrane	25
The microtubule-associated protein She1 coordinates directional spindle positioning by spatially restricting dynein activity	25
Histone deacetylase 7 mediates lipopolysaccharide-inducible mitochondrial fission in macrophages	25
Comparative analysis of vertebrates reveals that mouse primordial oocytes do not contain a Balbiani body	25
Dynamics of intracellular cGMP during chemotaxis in Dictyostelium cells	25
MitoRUSH as a tool to study the efficiency of mitochondrial import in complex I-deficient cells	25
Nucleophagy contributes to genome stability through degradation of type II topoisomerases A and B and nucleolar components	25
The role of mitochondrial dynamics in mtDNA maintenance	24
First person – Aranya Pal and Prabin Bawali	24
Local DNA synthesis is critical for DNA repair during oocyte maturation	24
First person – Hatwan Nadir	24
Trophoblast organoids with physiological polarity model placental structure and function	24
First person – Rebeka Tomasin	23
The histone variant macroH2A1.1 regulates RNA polymerase II-paused genes within defined chromatin interaction landscapes	23

Rerouting trafficking circuits through posttranslational SNARE modifications	23
Schwann cells are axo-protective after injury irrespective of myelination status in mouse Schwann cell–neuron cocultures	23
The scaffold protein CasL restrains membrane blebbing and promotes T cell migration	23
A WDR47 homolog facilitates ciliogenesis by modulating intraflagellar transport	23
Evolving circuitries in plant signaling cascades	23
Lipid-driven CFTR clustering is impaired in cystic fibrosis and restored by corrector drugs	22
ALFY localizes to early endosomes and cellular protrusions to facilitate directional cell migration	22
First person – Shekhar Saha	22
Interview with Associate Editor Pedro Carvalho	22
First person – Chia-Li Liao	22
Mitochondrial respiration promotes Cdc37-dependent stability of the Cdk1 homolog Cdc28	22
First person – Kenrick Waite	22
First person – Kristina Ehring	22
First person – Franziska Lehne	22
Functions of neuronal Synaptobrevin in the post-Golgi transport of Rhodopsin in Drosophila photoreceptors	21
Cooperation of membrane-translocated syntaxin4 and basement membrane for dynamic mammary epithelial morphogenesis	21
First person – Aimee Uyehara	21
First person – Ana Popović	21
Corona XLVI – Oh my, Omicron!	21
EPLIN-β is a novel substrate of ornithine decarboxylase antizyme 1 and mediates cellular migration	21
STAT3 signaling induced by IL-6 family cytokines modulates angiogenesis	21
First person – Pablo Sánchez and Franziska Kriegenburg	21
Interview with Florence Niedergang – President of the French Society for Cell Biology	21
Rac1 and Rac3 GTPases and TPC2 are required for axonal outgrowth and migration of cortical interneurons	20
Incorporation of 53BP1 into phase-separated bodies in cancer cells during aberrant mitosis	20
Transendothelial migration induces differential migration dynamics of leukocytes in tissue matrix	20
Links between autophagy and tissue mechanics	20
30 years of nanobodies – an ongoing success story of small binders in biological research	20
Myosin-X recruits lamellipodin to filopodia tips	20
Cristae shaping and dynamics in mitochondrial function	20
New insights into FAK structure and function in focal adhesions	20
SART3 associates with a post-splicing complex	20
First person – Marta Grifell-Junyent	20
Impaired biogenesis of renin granules in the juxtaglomerular cells of Vps33a (D251E) murine mutant	20
Meeting report – Desmosome dysfunction and disease: Alpine desmosome disease meeting	20
Cell scientist to watch – Angelika Harbauer	20
First person – Daniel Lagunas-Gomez	20
Phosphorylation of the Aly3 C-terminus impedes aberrant endocytosis of Schizosaccharomyces pombe hexose transporter Ght5	19
Disordered hinge regions of the AP-3 adaptor complex promote vesicle budding from the late Golgi in yeast	19
First person – Mira Kuzmić	19
First person – Harini Iyer	19
Dynamic mechanisms for membrane skeleton transitions	19
First person – Alex van Vliet	19
First person – Jiwon Lee	19
First person – Rinka Hata	19
Toxoplasma gondiiscavenges mammalian host organelles through the usurpation of host ESCRT-III and Vps4A	19
SAF-A promotes origin licensing and replication fork progression to ensure robust DNA replication	19
Membrane tethers at a glance	18
First person – Kazuhiro Kajiwara	18
PIKFYVE inhibition induces endosome- and lysosome-derived vacuole enlargement via ammonium accumulation	18
Complexity and self-organization in the evolution of cell polarization	18
Say hello, wave goodbye	18
Label2label: training a neural network to selectively restore cellular structures in fluorescence microscopy	18
Qui(e)t	18
First person – Tadayuki Komori	17
Neutral sphingomyelinase 2 controls exosome secretion by counteracting V-ATPase-mediated endosome acidification	17
Emerging roles of lipid transfer protein dimerization	17
Emerging roles of p300/CBP in autophagy and autophagy-related human disorders	17
Pyruvate plus uridine augments mitochondrial respiration and prevents cardiac hypertrophy in zebrafish and H9c2 cells	17
Angiomotin isoform 2 promotes binding of PALS1 to KIF13B at primary cilia and regulates ciliary length and signaling	17
Epithelial cell extrusion at a glance	17
An evolutionary perspective on the relationship between kinetochore size and CENP-E dependence for chromosome alignment	17
First person – Chandra Ramakrishnan	17
ISG20L1 acts as a co-activator of DAPK1 in the activation of the p53-dependent cell death pathway	17
Urinary renal epithelial cells for NPHP1 phenotyping and personalized therapeutic response	17
Src- and Abl-family kinases activate spleen tyrosine kinase to maximize phagocytosis and Leishmania infection	16
Low kindlin-3 levels in osteoclasts of kindlin-3 hypomorphic mice result in osteopetrosis due to leaky sealing zones	16
Necroptosis at a glance	16
Distinct nuclear and cytoplasmic assemblies and interactomes of the mammalian CTLH E3 ligase complex	16
First person – Emily McParland and Noah Gurley	16
Peroxisomal support of mitochondrial respiratory efficiency promotes ER stress survival	16
First person – Inga Mohr	16
A novel homeostatic mechanism tunes PI(4,5)P2-dependent signaling at the plasma membrane	16
AMPK promotes Arf6 activation in a kinase-independent manner upon glucose starvation	16
Interview with the 2025 BSCB Women in Cell Biology Early Career Medal Winner Helen Weavers	16
Ezrin knockdown reduces procaterol-stimulated ciliary beating without morphological changes in mouse airway cilia	16
Fetuin-A secretion from β-cells leads to accumulation of macrophages in islets, aggravates inflammation and impairs insulin secretion	16
Deep learning ­– promises for 3D nuclear imaging: a guide for biologists	16
First person – Harini Krishnan	16
Lipophagy at a glance	16

Smaug1 membrane-less organelles respond to AMPK and mTOR and affect mitochondrial function	16
Correction: An evolutionarily distinct chaperone promotes 20S proteasome α-ring assembly in plants	16
First person – Vartika Sharma	16
Interview with Jennifer Lippincott-Schwartz	15
Quantitative proteomics reveals insights into the assembly of IFT trains and ciliary assembly	15
Ankyrin-B is required for the establishment and maintenance of lens cytoarchitecture, mechanics and clarity	15
Filopodial protrusion driven by density-dependent Ena–TOCA-1 interactions	15
First person – Keira L. Rice	15
The SARS-CoV-2 protein NSP2 enhances microRNA-mediated translational repression	15
Radial spoke protein 9 is necessary for axoneme assembly in Plasmodium but not in trypanosomatid parasites	15
Substrate adhesion determines migration during mesenchymal cell condensation in chondrogenesis	15
AMG232 inhibits angiogenesis in glioma through the p53–RBM4–VEGFR2 pathway	15
Correction: An SR protein is essential for activating DNA repair in malaria parasites	15
Nuclear F-actin and Lamin A antagonistically modulate nuclear shape	15
First person – Joe Tyler	15
Actin assembly requirements of the formin Fus1 to build the fusion focus	15
Localized TPC1-mediated Ca2+ release from endolysosomes contributes to myoseptal junction development in zebrafish	15
Evidence of 14-3-3 proteins contributing to kinetochore integrity and chromosome congression during mitosis	15
Multiple regions within junctin drive its interaction with calsequestrin-1 and its localization to triads in skeletal muscle	15
Structured RhoGEF recruitment drives myosin II organization on large exocytic vesicles	15
The Dilute domain in Canoe is not essential for linking cell junctions to the cytoskeleton but supports morphogenesis robustness	14
cellPLATO – an unsupervised method for identifying cell behaviour in heterogeneous cell trajectory data	14
Dishevelled coordinates phosphoinositide kinases PI4KIIIα and PIP5KIγ for efficient PtdInsP2 synthesis	14
A single-molecule localization microscopy method for tissues reveals nonrandom nuclear pore distribution in Drosophila	14
Visualizing endogenous Rho activity with an improved localization-based, genetically encoded biosensor	14
Human sperm rotate with a conserved direction during free swimming in four dimensions	14
Renal tissue-resident macrophages promote cystogenesis in early polycystic kidney disease	14
THSC/TREX-2 deficiency causes replication stress and genome instability in Caenorhabditis elegans	14
Artificial tethering of constitutive centromere-associated network proteins induces CENP-A deposition without Knl2 in DT40 cells	14
The worst II – eight days a week	14
Go with the flow – bulk transport by molecular motors	14
Correction: Defining the dynamin-based ring organizing center on the peroxisome-dividing machinery isolated from Cyanidioschyzon merolae	14
Expression of Concern: Caspase-dependent initiation of apoptosis and necrosis by the Fas receptor in lymphoid cells: onset of necrosis is associated with delayed ceramide increase	14
Single-chromosome dynamics reveals locus-dependent dynamics and chromosome territory orientation	14
First person – Guan Chen	14
MAPK activation drives male and female mouse teratocarcinomas from late primordial germ cells	14
The Cdc42 GTPase-activating protein Rga6 promotes the cortical localization of septin	14
Arsenic binds to nuclear transport factors and disrupts nucleocytoplasmic transport	14
First person – Masashi Nambu	13
First person – Mitchell Leih	13
First person – Anthony Dornan	13
First person – Keiichiro Sakai	13
First person – Julia Romano	13
First person – Marc Severin	13
SGIP1 binding to the α-helical H9 domain of cannabinoid receptor 1 promotes axonal surface expression	13
First person – Yuan Gao	13
Nuclear segmentation facilitates neutrophil migration	13
Nuclear translocation of the tagged endogenous MAPK MPK-1 denotes a subset of activation events in C. elegans development	13
ADAD2 regulates heterochromatin in meiotic and post-meiotic male germ cells via translation of MDC1	13
Coilin and SUMOylation influence PARP1 dynamics and the DNA damage response	13
First person – Laura Quirion	13
First person – Caroline König	13
Quality control of un-imported mitochondrial proteins at a glance	13
Endosomal vesicle fusion machinery is involved with the contractile vacuole in Dictyostelium discoideum	13
The small ARF-like 2 GTPase TITAN5 is linked with the dynamic regulation of IRON-REGULATED TRANSPORTER 1	13
Believing is seeing – the deceptive influence of bias in quantitative microscopy	13
First person – Clara Mutschler	13
The laminin-binding integrins regulate nuclear factor κB-dependent epithelial cell polarity and inflammation	13
First person – Mohima Mukherjee	13
First person – Nima Taefehshokr	13
filoVision – using deep learning and tip markers to automate filopodia analysis	13
First person – Zhong-Qiu Yu	13
Vertebrate lonesome kinase modulates the hepatocyte secretome to prevent perivascular liver fibrosis and inflammation	13
N-acetylation of secreted proteins in Apicomplexa is widespread and is independent of the ER acetyl-CoA transporter AT1	13
KRAP regulates mitochondrial Ca2+ uptake by licensing IP3 receptor activity and stabilizing ER–mitochondrial junctions	13
First person – Sarah Barger	13
The system II – getting to bed	13
Shock drives a STAT3 and JunB-mediated coordinated transcriptional and DNA methylation response in the endothelium	13
Skeletal ciliopathy variants of the dynein-2 DYNC2LI1 subunit impair osteogenic differentiation of mesenchymal stem cells	12
B cell receptor-induced protein dynamics and the emerging role of SUMOylation revealed by proximity proteomics	12
HDLs extract lipophilic drugs from cells	12
First person – Poulomi Das	12
Evolutionary conservation of systemic and reversible amyloid aggregation	12
The APC/C targets the Cep152–Cep63 complex at the centrosome to regulate mitotic spindle assembly	12
StARD9 is a novel lysosomal kinesin required for membrane tubulation, cholesterol transport and Purkinje cell survival	12
The E2 ubiquitin-conjugating enzymes UBE2D1 and UBE2D2 regulate VEGFR2 dynamics and endothelial function	12
First person – Agostina Di Pizio	12
Correction: TPL2-mediated activation of ERK1 and ERK2 regulates the processing of pre-TNFα in LPS-stimulated macrophages	12
Myosin II tension sensors visualize force generation within the actin cytoskeleton in living cells	12
Localization of the tubby domain, a PI(4,5)P2 biosensor, to E-Syt3-rich endoplasmic reticulum–plasma membrane junctions	12
First person – Marielle Saclier	12
First person – Ezgi Odabasi	12
Salinomycin disturbs Golgi function and specifically affects cells in epithelial-to-mesenchymal transition	12
First person – Sean Gombart	12
Phospholipase C-related but catalytically inactive protein acts as a positive regulator of insulin signalling in adipocytes	12
PLK1 controls centriole distal appendage formation and centrobin removal via independent pathways	12
Cellular and molecular functions of SETD2 in the central nervous system	12
Regulation of Wnt distribution and function by Drosophila glypicans	12
Stem cell expression of CXCR4 regulates tissue composition in the vomeronasal organ	12
A genome-wide genetic screen identifies CYRI-B as a negative regulator of CEACAM3-mediated phagocytosis	12
A WNT4- and DKK3-driven canonical to noncanonical Wnt signaling switch controls multiciliogenesis	12
Centrosome amplification promotes cell invasion via cell–cell contact disruption and Rap-1 activation	12
The UbiB family member Cqd1 forms a novel membrane contact site in mitochondria	12
Vimentin intermediate filaments provide structural stability to the mammalian Golgi complex	12
Perspectives in collective cell migration – moving forward	12