American Journal of Psychiatry

Article	Citations
The American Psychiatric Association Practice Guideline for the Treatment of Patients With Schizophrenia	370
Synthesizing the Evidence for Ketamine and Esketamine in Treatment-Resistant Depression: An International Expert Opinion on the Available Evidence and Implementation	339
Stanford Neuromodulation Therapy (SNT): A Double-Blind Randomized Controlled Trial	296
Improving Suicide Prevention Through Evidence-Based Strategies: A Systematic Review	250
A Randomized Controlled Trial of Repeated Ketamine Administration for Chronic Posttraumatic Stress Disorder	141
From Womb to Neighborhood: A Racial Analysis of Social Determinants of Psychosis in the United States	139
Neuroimaging Biomarkers in Schizophrenia	137
An Exposure-Wide and Mendelian Randomization Approach to Identifying Modifiable Factors for the Prevention of Depression	135
Variable Patterns of Remission From ADHD in the Multimodal Treatment Study of ADHD	133
Subcortical Brain Volume, Regional Cortical Thickness, and Cortical Surface Area Across Disorders: Findings From the ENIGMA ADHD, ASD, and OCD Working Groups	131
Elevated C-Reactive Protein in Patients With Depression, Independent of Genetic, Health, and Psychosocial Factors: Results From the UK Biobank	121
The Overlapping Neurobiology of Induced and Pathological Anxiety: A Meta-Analysis of Functional Neural Activation	114
Addiction as a Coping Response: Hyperkatifeia, Deaths of Despair, and COVID-19	106
Harmonizing the Neurobiology and Treatment of Obsessive-Compulsive Disorder	104
A Brain-Centric Model of Suicidal Behavior	103
Dismantling Structural Racism in Psychiatry: A Path to Mental Health Equity	98
Association of Prenatal Alcohol Exposure With Psychological, Behavioral, and Neurodevelopmental Outcomes in Children From the Adolescent Brain Cognitive Development Study	97
Anticholinergic Medication Burden–Associated Cognitive Impairment in Schizophrenia	96
Association Between Systemic Inflammation and Individual Symptoms of Depression: A Pooled Analysis of 15 Population-Based Cohort Studies	90
Psychotherapy at a Distance	83
The Impact of COVID-19 on Individuals With Intellectual and Developmental Disabilities: Clinical and Scientific Priorities	76
Autism Spectrum Disorder Genetics and the Search for Pathological Mechanisms	74
Effects of Olanzapine Combined With Samidorphan on Weight Gain in Schizophrenia: A 24-Week Phase 3 Study	74
Genome-Wide Association Study of Suicide Death and Polygenic Prediction of Clinical Antecedents	73
Efficacy of Intravenous Ketamine in Adolescent Treatment-Resistant Depression: A Randomized Midazolam-Controlled Trial	72

Defining Recovery From Alcohol Use Disorder: Development of an NIAAA Research Definition	71
Adjunctive Ketamine With Relapse Prevention–Based Psychological Therapy in the Treatment of Alcohol Use Disorder	66
A Genetics-First Approach to Dissecting the Heterogeneity of Autism: Phenotypic Comparison of Autism Risk Copy Number Variants	66
Large-Scale Functional Brain Network Architecture Changes Associated With Trauma-Related Dissociation	64
Effect of AXS-05 (Dextromethorphan-Bupropion) in Major Depressive Disorder: A Randomized Double-Blind Controlled Trial	64
Early Adversity and Development: Parsing Heterogeneity and Identifying Pathways of Risk and Resilience	64
Identification of a Signaling Mechanism by Which the Microbiome Regulates Th17 Cell-Mediated Depressive-Like Behaviors in Mice	63
Item-Level Genome-Wide Association Study of the Alcohol Use Disorders Identification Test in Three Population-Based Cohorts	63
Efficacy and Safety of Lumateperone for Major Depressive Episodes Associated With Bipolar I or Bipolar II Disorder: A Phase 3 Randomized Placebo-Controlled Trial	61
Toward a Better Understanding of the Mechanisms and Pathophysiology of Anhedonia: Are We Ready for Translation?	60
The Evolving Nexus of Sleep and Depression	60
Disparities in Screening and Treatment of Cardiovascular Diseases in Patients With Mental Disorders Across the World: Systematic Review and Meta-Analysis of 47 Observational Studies	59
Maintenance Treatment With Long-Acting Injectable Antipsychotics for People With Nonaffective Psychoses: A Network Meta-Analysis	57
The American Psychiatric Association Practice Guideline for the Treatment of Patients With Eating Disorders	57
Sleep Abnormalities in Schizophrenia: State of the Art and Next Steps	56
Incident Major Depressive Disorder Predicted by Three Measures of Insulin Resistance: A Dutch Cohort Study	56
Alcohol, Tobacco, and Comorbid Psychiatric Disorders and Associations With Sexual Identity and Stress-Related Correlates	56
Zuranolone for the Treatment of Postpartum Depression	55
Well-Being, Burnout, and Depression Among North American Psychiatrists: The State of Our Profession	55
Effect Sizes of Deletions and Duplications on Autism Risk Across the Genome	53
Pervasively Thinner Neocortex as a Transdiagnostic Feature of General Psychopathology	52
REL-1017 (Esmethadone) as Adjunctive Treatment in Patients With Major Depressive Disorder: A Phase 2a Randomized Double-Blind Trial	52
Childhood Maltreatment and Mental Health Problems: A Systematic Review and Meta-Analysis of Quasi-Experimental Studies	52
The Intergenerational Impact of Structural Racism and Cumulative Trauma on Depression	52
Disrupted Dorsal Mid-Insula Activation During Interoception Across Psychiatric Disorders	51
Antibodies From Children With PANDAS Bind Specifically to Striatal Cholinergic Interneurons and Alter Their Activity	49
Functional Connectome Prediction of Anxiety Related to the COVID-19 Pandemic	49
Subjective Responses to Alcohol in the Development and Maintenance of Alcohol Use Disorder	48
Charting the Landscape of Genetic Overlap Between Mental Disorders and Related Traits Beyond Genetic Correlation	48
Structural Racism and Suicide Prevention for Ethnoracially Minoritized Youth: A Conceptual Framework and Illustration Across Systems	48
Risks and Benefits of Cannabis and Cannabinoids in Psychiatry	47
Fifty Years of Research on Schizophrenia: The Ascendance of the Glutamatergic Synapse	47
Brain-Based Biotypes of Psychiatric Vulnerability in the Acute Aftermath of Trauma	47
Functional Neuroimaging in PTSD: From Discovery of Underlying Mechanisms to Addressing Diagnostic Heterogeneity	45
Muscarinic Acetylcholine Receptor Agonists as Novel Treatments for Schizophrenia	44
Must Psilocybin Always “Assist Psychotherapy”?	44
Association of Inflammatory Activity With Larger Neural Responses to Threat and Reward Among Children Living in Poverty	44
Ulipristal Acetate for Treatment of Premenstrual Dysphoric Disorder: A Proof-of-Concept Randomized Controlled Trial	44
Anxiety, Depression, and Suicide in Youth	44
Racial Disparities in Adversity During Childhood and the False Appearance of Race-Related Differences in Brain Structure	43
On the Genetic and Environmental Relationship Between Suicide Attempt and Death by Suicide	43
Impact of the KCNQ2/3 Channel Opener Ezogabine on Reward Circuit Activity and Clinical Symptoms in Depression: Results From a Randomized Controlled Trial	42
Electroconvulsive Therapy in Mania: A Review of 80 Years of Clinical Experience	42
Maternal Psychological Resilience During Pregnancy and Newborn Telomere Length: A Prospective Study	42
Functional Connectivity Mapping for rTMS Target Selection in Depression	42
Examining and Modulating Neural Circuits in Psychiatric Disorders With Transcranial Magnetic Stimulation and Electroencephalography: Present Practices and Future Developments	42
Whole Brain White Matter Tract Deviation and Idiosyncrasy From Normative Development in Autism and ADHD and Unaffected Siblings Link With Dimensions of Psychopathology and Cognition	41
Surging Racial Disparities in the U.S. Overdose Crisis	41
Association of Prefrontal-Striatal Functional Pathology With Alcohol Abstinence Days at Treatment Initiation and Heavy Drinking After Treatment Initiation	41
Contraception for Women With Psychiatric Disorders	41

Moderation of Prazosin’s Efficacy by Alcohol Withdrawal Symptoms	40
Coordinate-Based Network Mapping of Brain Structure in Major Depressive Disorder in Younger and Older Adults: A Systematic Review and Meta-Analysis	40
A Novel, Brief, Fully Automated Intervention to Extend the Antidepressant Effect of a Single Ketamine Infusion: A Randomized Clinical Trial	39
Early Parenting Intervention Effects on Brain Responses to Maternal Cues Among High-Risk Children	39
Long-Term Cannabis Use and Cognitive Reserves and Hippocampal Volume in Midlife	39
Diagnostic Classification for Human Autism and Obsessive-Compulsive Disorder Based on Machine Learning From a Primate Genetic Model	39
Polygenic Risk and Progression to Bipolar or Psychotic Disorders Among Individuals Diagnosed With Unipolar Depression in Early Life	39
Genes To Mental Health (G2MH): A Framework to Map the Combined Effects of Rare and Common Variants on Dimensions of Cognition and Psychopathology	38
Cell-Type-Specific Impact of Glucocorticoid Receptor Activation on the Developing Brain: A Cerebral Organoid Study	38
20-Year Prospective, Sequential Follow-Up Study of Heterogeneity in Associations of Duration of Untreated Psychosis With Symptoms, Functioning, and Quality of Life Following First-Episode Psychosis	37
Clozapine Intoxication in COVID-19	36
Interindividual Differences in Cortical Thickness and Their Genomic Underpinnings in Autism Spectrum Disorder	36
Association of ECT With Risks of All-Cause Mortality and Suicide in Older Medicare Patients	36
New Challenges in Addiction Medicine: COVID-19 Infection in Patients With Alcohol and Substance Use Disorders—The Perfect Storm	36
Trends in Outpatient Psychotherapy Provision by U.S. Psychiatrists: 1996–2016	35
Zuranolone for the Treatment of Adults With Major Depressive Disorder: A Randomized, Placebo‐Controlled Phase 3 Trial	34
Diagnosis- and Cell Type-Specific Mitochondrial Functional Pathway Signatures in Schizophrenia and Bipolar Disorder	34
Thalamic Nuclei Volumes in Psychotic Disorders and in Youths With Psychosis Spectrum Symptoms	34
Differential Patterns of Delayed Emotion Circuit Maturation in Abused Girls With and Without Internalizing Psychopathology	34
Evaluating the Machine Learning Literature: A Primer and User’s Guide for Psychiatrists	33
Subcortical Brain Development in Autism and Fragile X Syndrome: Evidence for Dynamic, Age- and Disorder-Specific Trajectories in Infancy	33
The Sources of Parent-Child Transmission of Risk for Suicide Attempt and Deaths by Suicide in Swedish National Samples	33
Telehealth During COVID-19—Does Everyone Have Equal Access?	32
The Amygdala and Depression: A Sober Reconsideration	32
Persistent Dissociation and Its Neural Correlates in Predicting Outcomes After Trauma Exposure	32
The Importance of Conduct Disorder in the Treatment of Violence in Schizophrenia: Efficacy of Clozapine Compared With Olanzapine and Haloperidol	32
In Search of Biomarkers to Guide Interventions in Autism Spectrum Disorder: A Systematic Review	31
Association of Missense Mutation in FOLH1 With Decreased NAAG Levels and Impaired Working Memory Circuitry and Cognition	31
The Autism Biomarkers Consortium for Clinical Trials: Initial Evaluation of a Battery of Candidate EEG Biomarkers	31
Two Decades of Anxiety Neuroimaging Research: New Insights and a Look to the Future	31
Flexible Buprenorphine/Naloxone Model of Care for Reducing Opioid Use in Individuals With Prescription-Type Opioid Use Disorder: An Open-Label, Pragmatic, Noninferiority Randomized Controlled Trial	31
Pharmacotherapies for Treatment-Resistant Depression: How Antipsychotics Fit in the Rapidly Evolving Therapeutic Landscape	31
Predictive Value of Acute Neuroplastic Response to rTMS in Treatment Outcome in Depression: A Concurrent TMS-fMRI Trial	30
From Rare Copy Number Variants to Biological Processes in ADHD	30
GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors	30
CBT for Prolonged Grief in Children and Adolescents: A Randomized Clinical Trial	30
Naltrexone-Bupropion and Behavior Therapy, Alone and Combined, for Binge-Eating Disorder: Randomized Double-Blind Placebo-Controlled Trial	29
Evidence for Dopamine Abnormalities in the Substantia Nigra in Cocaine Addiction Revealed by Neuromelanin-Sensitive MRI	28
Decoding Shared Versus Divergent Transcriptomic Signatures Across Cortico-Amygdala Circuitry in PTSD and Depressive Disorders	28
Psychiatry Diversity Leadership in Academic Medicine: Guidelines for Success	28
Time Course of Relapse Following Acute Treatment for Anorexia Nervosa	28
Sustained Effect of a Brief Video in Reducing Public Stigma Toward Individuals With Psychosis: A Randomized Controlled Trial of Young Adults	28
Reward Processing in Children With Disruptive Behavior Disorders and Callous-Unemotional Traits in the ABCD Study	27
Impact of COVID-19 Telehealth Policy Changes on Buprenorphine Treatment for Opioid Use Disorder	27
Multimodal Neuroimaging of Suicidal Thoughts and Behaviors in a U.S. Population-Based Sample of School-Age Children	27
Effect of Experimental Manipulation of the Orbitofrontal Cortex on Short-Term Markers of Compulsive Behavior: A Theta Burst Stimulation Study	27
Sublingual Buprenorphine-Naloxone Compared With Injection Naltrexone for Opioid Use Disorder: Potential Utility of Patient Characteristics in Guiding Choice of Treatment	27
The World Health Organization Risk Drinking Levels Measure of Alcohol Consumption: Prevalence and Health Correlates in Nationally Representative Surveys of U.S. Adults, 2001–2002 and 2012–2013	26
Dementia Is More Than Memory Loss: Neuropsychiatric Symptoms of Dementia and Their Nonpharmacological and Pharmacological Management	26
Evolution, Emotion, and Episodic Engagement	26
Shared and Unique Changes in Brain Connectivity Among Depressed Patients After Remission With Pharmacotherapy Versus Psychotherapy	25
Association Between Benzodiazepine or Z-Drug Prescriptions and Drug-Related Poisonings Among Patients Receiving Buprenorphine Maintenance: A Case-Crossover Analysis	25
Association of Neural Reward Circuitry Function With Response to Psychotherapy in Youths With Anxiety Disorders	25
Schizophrenia Imaging Signatures and Their Associations With Cognition, Psychopathology, and Genetics in the General Population	24
Variable Emergence of Autism Spectrum Disorder Symptoms From Childhood to Early Adulthood	24
The Neglected Role of Psychotherapy for Treatment-Resistant Depression	24
Treatment-Specific Associations Between Brain Activation and Symptom Reduction in OCD Following CBT: A Randomized fMRI Trial	24
Synaptic Variability and Cortical Gamma Oscillation Power in Schizophrenia	24
Let’s Be Clear That “Autism Spectrum Disorder Symptoms” Are Not Always Related to Autism Spectrum Disorder	24
Prevalence and Correlates of Cannabis Use and Cannabis Use Disorder Among U.S. Veterans: Results From the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC-III)	24
Learning About Safety: Conditioned Inhibition as a Novel Approach to Fear Reduction Targeting the Developing Brain	24
Genetics and Brain Transcriptomics of Completed Suicide	24
Trends in Cannabis Use Disorder Diagnoses in the U.S. Veterans Health Administration, 2005–2019	23
Project Harmony: A Meta-Analysis With Individual Patient Data on Behavioral and Pharmacologic Trials for Comorbid Posttraumatic Stress and Alcohol or Other Drug Use Disorders	23
Recent Advances on Social Determinants of Mental Health: Looking Fast Forward	23
Transforming Discoveries About Cortical Microcircuits and Gamma Oscillations Into New Treatments for Cognitive Deficits in Schizophrenia	22
Neuromodulation Strategies for the Treatment of Depression	22
Intrusive Traumatic Reexperiencing: Pathognomonic of the Psychological Response to Traumatic Stress	22
The Prehistory of Psychiatric Genetics: 1780–1910	22
A Case of Prolonged Mania, Psychosis, and Severe Depression After Psilocybin Use: Implications of Increased Psychedelic Drug Availability	22
Structural Racism as a Proximal Cause for Race-Related Differences in Psychiatric Disorders	21
Psychedelics as Transformative Therapeutics	21
Digital Intervention for Cognitive Deficits in Major Depression: A Randomized Controlled Trial to Assess Efficacy and Safety in Adults	21
Association of Cannabis Use–Related Predictor Variables and Self-Reported Psychotic Disorders: U.S. Adults, 2001–2002 and 2012–2013	21
Technology and Mental Health: State of the Art for Assessment and Treatment	21
The Nature of Prefrontal Cortical GABA Neuron Alterations in Schizophrenia: Markedly Lower Somatostatin and Parvalbumin Gene Expression Without Missing Neurons	21
Antidepressant Effects of Psilocybin in the Absence of Psychedelic Effects	21
Association of Medication Treatment for Opioid Use Disorder With Suicide Mortality	20
Office-Based Methadone Treatment for Opioid Use Disorder and Pharmacy Dispensing: A Scoping Review	20
Transdiagnostic Connectome-Based Prediction of Craving	20

From Awareness to Action: An Urgent Call to Address the Inadequacy of Treatment for Anorexia Nervosa	20
Cannabis and Psychosis: Recent Epidemiological Findings Continuing the “Causality Debate”	20
Efficacy of Combining Varenicline and Naltrexone for Smoking Cessation and Drinking Reduction: A Randomized Clinical Trial	19
Intentional Drug Overdose Deaths in the United States	19
Infant Visual Brain Development and Inherited Genetic Liability in Autism	19
Mortality Among Parkinson’s Disease Patients Treated With Pimavanserin or Atypical Antipsychotics: An Observational Study in Medicare Beneficiaries	19
Disruptive Behavior Disorders: The Challenge of Delineating Mechanisms in the Face of Heterogeneity	19
Low-Dose Testosterone Augmentation for Antidepressant-Resistant Major Depressive Disorder in Women: An 8-Week Randomized Placebo-Controlled Study	19
Aberrant Developmental Patterns of Gamma-Band Response and Long-Range Communication Disruption in Youths With 22q11.2 Deletion Syndrome	19
Neurobiological Correlates of Change in Adaptive Behavior in Autism	19
The Genetic Architecture of Obsessive-Compulsive Disorder: Contribution of Liability to OCD From Alleles Across the Frequency Spectrum	18
Adjunctive Cariprazine for the Treatment of Patients With Major Depressive Disorder: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study	18
Mood Disorders and Outcomes of COVID-19 Hospitalizations	18
A Longitudinal Study of Resting-State Connectivity and Response to Psychostimulant Treatment in ADHD	18
Leveraging Large-Scale Genetics of PTSD and Cardiovascular Disease to Demonstrate Robust Shared Risk and Improve Risk Prediction Accuracy	18
Effects of Gabapentin on Dorsal Anterior Cingulate Cortex GABA and Glutamate Levels and Their Associations With Abstinence in Alcohol Use Disorder: A Randomized Clinical Trial	18
Insights Into Suicide and Depression	18
Lyme Borreliosis and Associations With Mental Disorders and Suicidal Behavior: A Nationwide Danish Cohort Study	17
A Call to Protect the Health Care Workers Fighting COVID-19 in the United States	17
Genetic, Clinical, and Sociodemographic Factors Associated With Stimulant Treatment Outcomes in ADHD	17
The Link Between Autism and Sex-Related Neuroanatomy, and Associated Cognition and Gene Expression	17
The Impact of Alcohol and Other Substance Use Disorders on Mortality in Patients With Eating Disorders: A Nationwide Register-Based Retrospective Cohort Study	17
Neonatal Brain Response to Deviant Auditory Stimuli and Relation to Maternal Trait Anxiety	17